Published in J Biol Chem on February 22, 2010
TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem (2010) 2.66
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A (2012) 1.97
Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci U S A (2011) 1.79
Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion. Physiol Rev (2012) 1.71
International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels. Pharmacol Rev (2011) 1.67
Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels? Acta Pharmacol Sin (2011) 1.64
Dynamic modulation of ANO1/TMEM16A HCO3(-) permeability by Ca2+/calmodulin. Proc Natl Acad Sci U S A (2012) 1.63
Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A. J Biol Chem (2010) 1.58
Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron (2012) 1.50
Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. FASEB J (2011) 1.45
ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins. Am J Physiol Cell Physiol (2011) 1.43
Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon. J Clin Invest (2010) 1.29
Anoctamins. Pflugers Arch (2011) 1.29
Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin. J Gen Physiol (2014) 1.24
A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife (2014) 1.23
Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network. Proc Natl Acad Sci U S A (2012) 1.17
Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity. Mol Pain (2014) 1.16
Physiology of epithelial chloride and fluid secretion. Cold Spring Harb Perspect Med (2012) 1.16
Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1. Proc Natl Acad Sci U S A (2012) 1.13
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia. J Physiol (2012) 1.09
Pharmacological characterization of TMEM16A currents. Channels (Austin) (2014) 1.03
Location of release sites and calcium-activated chloride channels relative to calcium channels at the photoreceptor ribbon synapse. J Neurophysiol (2010) 1.02
Ca2+-activated Cl- channels at a glance. J Cell Sci (2012) 1.01
Inhibition of TMEM16A expression suppresses growth and invasion in human colorectal cancer cells. PLoS One (2014) 0.98
Epidermal growth factor chronically upregulates Ca(2+)-dependent Cl(-) conductance and TMEM16A expression in intestinal epithelial cells. J Physiol (2012) 0.94
Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels. Proc Natl Acad Sci U S A (2015) 0.92
New selective inhibitors of calcium-activated chloride channels - T16A(inh) -A01, CaCC(inh) -A01 and MONNA - what do they inhibit? Br J Pharmacol (2015) 0.92
Non-canonical translation start sites in the TMEM16A chloride channel. Biochim Biophys Acta (2013) 0.90
Cellular functions of TMEM16/anoctamin. Pflugers Arch (2016) 0.89
Subdued, a TMEM16 family Ca²⁺-activated Cl⁻channel in Drosophila melanogaster with an unexpected role in host defense. Elife (2013) 0.88
Apical Ca2+-activated potassium channels in mouse parotid acinar cells. J Gen Physiol (2012) 0.87
Severe defects in absorptive ion transport in distal colons of mice that lack ClC-2 channels. Gastroenterology (2011) 0.87
Anion permeation in calcium-activated chloride channels formed by TMEM16A from Xenopus tropicalis. Pflugers Arch (2013) 0.86
A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland. Proc Natl Acad Sci U S A (2015) 0.85
Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6). FASEB J (2014) 0.85
Presynaptic Localization and Possible Function of Calcium-Activated Chloride Channel Anoctamin 1 in the Mammalian Retina. PLoS One (2013) 0.84
Transepithelial bicarbonate secretion: lessons from the pancreas. Cold Spring Harb Perspect Med (2012) 0.84
Activation of the basolateral membrane Cl- conductance essential for electrogenic K+ secretion suppresses electrogenic Cl- secretion. Exp Physiol (2010) 0.83
The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis. Mol Biol Cell (2014) 0.83
Overexpression, crystallization and preliminary X-ray crystallographic analysis of the C-terminal cytosolic domain of mouse anoctamin 1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.83
Ca²⁺-dependent K⁺ channels in exocrine salivary glands. Cell Calcium (2014) 0.82
Ae4 (Slc4a9) Anion Exchanger Drives Cl- Uptake-dependent Fluid Secretion by Mouse Submandibular Gland Acinar Cells. J Biol Chem (2015) 0.81
Functional differences in the acinar cells of the murine major salivary glands. J Dent Res (2015) 0.80
Retrograde ductal administration of the adenovirus-mediated NDRG2 gene leads to improved sialaden hypofunction in estrogen-deficient rats. Mol Ther (2013) 0.80
Mechanism and synergism in epithelial fluid and electrolyte secretion. Pflugers Arch (2013) 0.80
Gating modes of calcium-activated chloride channels TMEM16A and TMEM16B. J Physiol (2015) 0.80
Two helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calcium. Pflugers Arch (2014) 0.79
Modulating Ca(2+) signals: a common theme for TMEM16, Ist2, and TMC. Pflugers Arch (2015) 0.79
Mechanism involved in Danshen-induced fluid secretion in salivary glands. World J Gastroenterol (2015) 0.78
Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels. Proc Natl Acad Sci U S A (2014) 0.78
A comprehensive strategy to identify stoichiometric membrane protein interactomes. Cell Logist (2012) 0.78
Regulation of Ca²⁺ release through inositol 1,4,5-trisphosphate receptors by adenine nucleotides in parotid acinar cells. Am J Physiol Gastrointest Liver Physiol (2011) 0.78
Hypoxia augments the calcium-activated chloride current carried by anoctamin-1 in cardiac vascular endothelial cells of neonatal mice. Br J Pharmacol (2014) 0.78
Selective serotonin reuptake inhibitors facilitate ANO6 (TMEM16F) current activation and phosphatidylserine exposure. Pflugers Arch (2015) 0.78
Characterization of Cardiac Anoctamin1 Ca²⁺-Activated Chloride Channels and Functional Role in Ischemia-Induced Arrhythmias. J Cell Physiol (2015) 0.77
Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. J Clin Invest (2016) 0.77
TRPC1 regulates calcium-activated chloride channels in salivary gland cells. J Cell Physiol (2015) 0.76
Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. PLoS One (2015) 0.75
Calmodulin regulation of TMEM16A and 16B Ca(2+)-activated chloride channels. Channels (Austin) (2015) 0.75
Multiple transcripts of anoctamin genes expressed in the mouse submandibular salivary gland. J Periodontal Implant Sci (2015) 0.75
HCO3- Transport through Anoctamin/Transmembrane Protein ANO1/TMEM16A in Pancreatic Acinar Cells Regulates Luminal pH. J Biol Chem (2016) 0.75
Extracellular protons enable activation of the Calcium-Dependent chloride Channel TMEM16A (ANO1). J Physiol (2016) 0.75
A mathematical model of calcium dynamics in HSY cells. PLoS Comput Biol (2017) 0.75
Coupling of TRPV6 and TMEM16A in epithelial principal cells of the rat epididymis. J Gen Physiol (2016) 0.75
EAVK "segment c" sequence confers Ca(2+)-dependent changes to the kinetics of full length human Ano1. Am J Physiol Gastrointest Liver Physiol (2017) 0.75
Comparative Effects of Chloride Channel Inhibitors on LRRC8/VRAC-Mediated Chloride Conductance. Front Pharmacol (2017) 0.75
Expression of anoctamin 1 is associated with advanced tumor stage in patients with non-small cell lung cancer and predicts recurrence after surgery. Clin Transl Oncol (2017) 0.75
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science (2008) 8.74
TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature (2008) 8.40
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell (2008) 7.79
Characteristics and physiological role of the Ca(2+)-activated Cl- conductance in smooth muscle. Am J Physiol (1996) 4.44
The vitelliform macular dystrophy protein defines a new family of chloride channels. Proc Natl Acad Sci U S A (2002) 3.73
Regulation of fluid and electrolyte secretion in salivary gland acinar cells. Annu Rev Physiol (2005) 2.94
Calcium-dependent chloride currents in isolated cells from rat lacrimal glands. J Physiol (1986) 2.85
Molecular physiology of bestrophins: multifunctional membrane proteins linked to best disease and other retinopathies. Physiol Rev (2008) 2.73
Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels. J Physiol (2008) 2.66
The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol (2008) 2.61
Structure-function analysis of the bestrophin family of anion channels. J Biol Chem (2003) 2.30
TMEM16B induces chloride currents activated by calcium in mammalian cells. Pflugers Arch (2009) 2.20
TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals. J Neurosci (2009) 2.19
The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1). J Gen Physiol (2006) 2.18
Neuronal Ca2+ -activated Cl- channels--homing in on an elusive channel species. Prog Neurobiol (2000) 2.11
Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem (2009) 2.07
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J Proteome Res (2009) 1.97
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A. J Biol Chem (2009) 1.89
Activation of calcium-dependent chloride channels in rat parotid acinar cells. J Gen Physiol (1996) 1.82
Mouse bestrophin-2 is a bona fide Cl(-) channel: identification of a residue important in anion binding and conduction. J Gen Physiol (2004) 1.79
Cystic fibrosis transmembrane conductance regulator regulates luminal Cl-/HCO3- exchange in mouse submandibular and pancreatic ducts. J Biol Chem (1999) 1.64
Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase. J Biol Chem (2001) 1.62
Immuno and functional characterization of CFTR in submandibular and pancreatic acinar and duct cells. Am J Physiol (1997) 1.56
Calcium-dependent chloride conductance in epithelia: is there a contribution by Bestrophin? Pflugers Arch (2007) 1.47
[Ca2+]i modulation of Cl- content controls cell volume in single salivary acinar cells during fluid secretion. Am J Physiol (1990) 1.44
Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland. Am J Physiol (1999) 1.37
Bestrophin Cl- channels are highly permeable to HCO3-. Am J Physiol Cell Physiol (2008) 1.35
Determinants of anion permeation in the second transmembrane domain of the mouse bestrophin-2 chloride channel. J Gen Physiol (2004) 1.33
Bestrophin-1 enables Ca2+-activated Cl- conductance in epithelia. J Biol Chem (2006) 1.31
Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn (2008) 1.30
A novel human Cl(-) channel family related to Drosophila flightless locus. J Biol Chem (2004) 1.29
The anion-selective pore of the bestrophins, a family of chloride channels associated with retinal degeneration. J Neurosci (2006) 1.27
Bestrophin-2 is involved in the generation of intraocular pressure. Invest Ophthalmol Vis Sci (2008) 1.22
Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family. Eur J Hum Genet (2002) 1.21
Membrane-specific regulation of Cl- channels by purinergic receptors in rat submandibular gland acinar and duct cells. J Biol Chem (1997) 1.21
Cloning and characterization of the murine Vmd2 RFP-TM gene family. Cytogenet Genome Res (2004) 1.20
Diversity of Cl(-) channels. Cell Mol Life Sci (2006) 1.15
A short motif in the C-terminus of mouse bestrophin 3 [corrected] inhibits its activation as a Cl channel. FEBS Lett (2006) 1.14
Purinergic P2X7 receptors mediate ATP-induced saliva secretion by the mouse submandibular gland. J Biol Chem (2008) 1.11
Cftr and ENaC ion channels mediate NaCl absorption in the mouse submandibular gland. J Physiol (2009) 1.11
Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands. Dev Biol (2008) 1.10
Regulation of membrane potential and fluid secretion by Ca2+-activated K+ channels in mouse submandibular glands. J Physiol (2007) 1.09
Activation of bestrophin Cl- channels is regulated by C-terminal domains. J Biol Chem (2007) 1.04
Data normalization before statistical analysis: keeping the horse before the cart. Trends Pharmacol Sci (1988) 1.00
Functional and molecular characterization of the fluid secretion mechanism in human parotid acinar cells. Am J Physiol Regul Integr Comp Physiol (2007) 1.00
Cellular function and control of volume-regulated anion channels. Cell Biochem Biophys (2001) 0.99
Apical maxi-K (KCa1.1) channels mediate K+ secretion by the mouse submandibular exocrine gland. Am J Physiol Cell Physiol (2008) 0.95
Protein kinase C regulation of P2X3 receptors is unlikely to involve direct receptor phosphorylation. Biochim Biophys Acta (2006) 0.95
Clcn2 encodes the hyperpolarization-activated chloride channel in the ducts of mouse salivary glands. Am J Physiol Gastrointest Liver Physiol (2008) 0.94
Sulphonic acid derivatives as probes of pore properties of volume-regulated anion channels in endothelial cells. Br J Pharmacol (1999) 0.89
A variant of the Ca2+-activated Cl channel Best3 is expressed in mouse exocrine glands. J Membr Biol (2008) 0.88
Regulation of basolateral Cl(-) channels in airway epithelial cells: the role of nitric oxide. J Membr Biol (2007) 0.87
The role of bestrophin in airway epithelial ion transport. FEBS Lett (2004) 0.86
A bicarbonate- and weak acid-permeable chloride conductance controlled by cytosolic Ca2+ and ATP in rat submandibular acinar cells. J Membr Biol (1996) 0.86
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet (2004) 6.11
Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A (2006) 4.87
Calcium-activated chloride channels. Annu Rev Physiol (2005) 4.67
Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nat Rev Neurosci (2005) 4.54
Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell (2005) 3.98
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet (2006) 3.79
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature (2005) 3.78
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci (2008) 3.33
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet (2006) 3.27
Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles. J Physiol (2009) 3.02
GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ Res (2006) 2.85
Epidermal stem cells arise from the hair follicle after wounding. FASEB J (2007) 2.81
MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes (2007) 2.80
Essential role for Dicer during skeletal muscle development. Dev Biol (2007) 2.76
Signaling microdomains define the specificity of receptor-mediated InsP(3) pathways in neurons. Neuron (2002) 2.75
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol (2008) 2.69
Effects of task-specific locomotor and strength training in adults who were ambulatory after stroke: results of the STEPS randomized clinical trial. Phys Ther (2007) 2.62
The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol (2008) 2.61
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways. J Biol Chem (2009) 2.59
The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res (2008) 2.53
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci (2008) 2.50
KCNQ/M currents in sensory neurons: significance for pain therapy. J Neurosci (2003) 2.40
Serum concentrations of macrophage inhibitory cytokine 1 (MIC 1) as a predictor of miscarriage. Lancet (2004) 2.39
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci U S A (2008) 2.32
Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum. Proc Natl Acad Sci U S A (2003) 2.31
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci (2012) 2.28
Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat Med (2007) 2.20
The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1). J Gen Physiol (2006) 2.18
AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists. Nat Neurosci (2003) 2.08
Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem (2009) 2.07
Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels. J Neurosci (2005) 2.05
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J (2009) 1.99
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J Proteome Res (2009) 1.97
Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice. Mol Cell Biol (2006) 1.97
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A (2012) 1.97
Chloride channels: often enigmatic, rarely predictable. Annu Rev Physiol (2010) 1.94
Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9. Clin Cancer Res (2006) 1.93
Evidence that SOX2 overexpression is oncogenic in the lung. PLoS One (2010) 1.93
Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation. Dev Dyn (2008) 1.91
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A. J Biol Chem (2009) 1.89
Calcineurin inhibitors decrease DNA repair and apoptosis in human keratinocytes following ultraviolet B irradiation. J Invest Dermatol (2005) 1.86
Probing the regulation of M (Kv7) potassium channels in intact neurons with membrane-targeted peptides. J Neurosci (2006) 1.83
The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans. J Clin Invest (2008) 1.82
ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity. Nat Neurosci (2010) 1.82
Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4. J Biol Chem (2004) 1.81
Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer. Cancer Res (2006) 1.79
Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci U S A (2011) 1.79
Two bestrophins cloned from Xenopus laevis oocytes express Ca(2+)-activated Cl(-) currents. J Biol Chem (2003) 1.76
Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity. J Invest Dermatol (2008) 1.76
Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers. Clin Cancer Res (2004) 1.74
Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons. Proc Natl Acad Sci U S A (2008) 1.74
Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma. Proc Natl Acad Sci U S A (2012) 1.73
A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery. J Biol Chem (2006) 1.70
Degeneration and regeneration of the intervertebral disc: lessons from development. Dis Model Mech (2010) 1.69
Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology. Circ Res (2012) 1.69
Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration. Proc Natl Acad Sci U S A (2002) 1.67
Chloride accumulation in mammalian olfactory sensory neurons. J Neurosci (2004) 1.66
Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels? Acta Pharmacol Sin (2011) 1.64
TREK-1 and Best1 channels mediate fast and slow glutamate release in astrocytes upon GPCR activation. Cell (2012) 1.60
The microRNA-processing enzyme dicer maintains juxtaglomerular cells. J Am Soc Nephrol (2010) 1.60
Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A. J Biol Chem (2010) 1.58
Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2. J Biol Chem (2002) 1.57
Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice. Dev Biol (2009) 1.55
Human retinal pigment epithelium cells as functional models for the RPE in vivo. Invest Ophthalmol Vis Sci (2011) 1.55
Formation and progression of sub-retinal pigment epithelium deposits in Efemp1 mutation knock-in mice: a model for the early pathogenic course of macular degeneration. Hum Mol Genet (2007) 1.54
Dicer1 is required for differentiation of the mouse male germline. Biol Reprod (2008) 1.52
Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum. Dev Biol (2008) 1.51
Systematic comparison of the human saliva and plasma proteomes. Proteomics Clin Appl (2009) 1.51
Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron (2012) 1.50
Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice. Hum Mol Genet (2007) 1.50
Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae. Mol Cell Biol (2002) 1.49
A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning. Dev Cell (2003) 1.48
Stoichiometry of expressed KCNQ2/KCNQ3 potassium channels and subunit composition of native ganglionic M channels deduced from block by tetraethylammonium. J Neurosci (2003) 1.47
The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism. Growth Factors (2011) 1.46
Expression and localization of bestrophin during normal mouse development. Invest Ophthalmol Vis Sci (2003) 1.45
ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins. Am J Physiol Cell Physiol (2011) 1.43
Gating of the polycystin ion channel signaling complex in neurons and kidney cells. FASEB J (2004) 1.43
Mortality among hourly motor vehicle manufacturing workers. J Occup Environ Med (2003) 1.41
Bestrophins and retinopathies. Pflugers Arch (2010) 1.41
The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells. Science (2004) 1.40
Sertoli cell Dicer is essential for spermatogenesis in mice. Dev Biol (2008) 1.37
Bestrophin Cl- channels are highly permeable to HCO3-. Am J Physiol Cell Physiol (2008) 1.35
Loss of hyperpolarization-activated Cl(-) current in salivary acinar cells from Clcn2 knockout mice. J Biol Chem (2002) 1.34
Symbiotic relationship between Streptococcus mutans and Candida albicans synergizes virulence of plaque biofilms in vivo. Infect Immun (2014) 1.34
Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif. J Cell Sci (2005) 1.33
Ano1 as a regulator of proliferation. Am J Physiol Gastrointest Liver Physiol (2011) 1.32
The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome. Cancer Res (2005) 1.32
Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells. Cancer Res (2003) 1.31
Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell (2007) 1.31
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract. Mamm Genome (2009) 1.31