PubRank

Irving L Weissman

Author PubWeight™ 556.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res 2006 17.42
2 Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003 14.35
3 A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003 12.81
4 Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003 12.54
5 Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med 2004 11.29
6 Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 2005 11.23
7 Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009 10.31
8 Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 2002 9.63
9 Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 2004 8.36
10 Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu Rev Immunol 2002 7.78
11 Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007 7.72
12 Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol 2002 7.03
13 Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A 2005 6.32
14 Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 2010 6.06
15 Stems cells and the pathways to aging and cancer. Cell 2008 5.99
16 Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med 2005 5.68
17 CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell 2009 5.30
18 Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell 2007 5.28
19 CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell 2009 5.22
20 Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR. Proc Natl Acad Sci U S A 2006 5.21
21 Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle. Cell 2004 5.20
22 Plasticity of adult stem cells. Cell 2004 5.13
23 Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature 2010 5.05
24 Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev 2003 4.71
25 In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation 2006 4.48
26 Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A 2003 4.41
27 Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev Cell 2002 4.37
28 Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol 2006 4.32
29 JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell 2004 4.28
30 The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A 2012 4.20
31 Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci U S A 2003 4.09
32 Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med 2012 4.05
33 Coronary arteries form by developmental reprogramming of venous cells. Nature 2010 3.95
34 Cancer stem cells in solid tumors. Curr Opin Biotechnol 2007 3.91
35 Endochondral ossification is required for haematopoietic stem-cell niche formation. Nature 2008 3.87
36 Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A 2009 3.87
37 Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche. Nat Med 2009 3.82
38 Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol 2011 3.81
39 Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J Exp Med 2003 3.74
40 Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell 2007 3.59
41 Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A 2002 3.50
42 Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A 2010 3.41
43 Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci U S A 2014 3.39
44 Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma. Cell 2010 3.37
45 Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci U S A 2008 3.27
46 Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies. Science 2013 3.25
47 Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat Med 2004 3.17
48 Differential expression of novel potential regulators in hematopoietic stem cells. PLoS Genet 2005 3.11
49 An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol 2011 3.05
50 Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. Nature 2011 3.03
51 Isolation and characterization of a protochordate histocompatibility locus. Nature 2005 2.96
52 Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proc Natl Acad Sci U S A 2011 2.96
53 Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med 2002 2.96
54 The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci U S A 2006 2.94
55 Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system. Annu Rev Med 2005 2.92
56 Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One 2008 2.85
57 Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci U S A 2006 2.83
58 Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47. Sci Transl Med 2010 2.79
59 Dysregulated gene expression networks in human acute myelogenous leukemia stem cells. Proc Natl Acad Sci U S A 2009 2.76
60 Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches. Science 2007 2.69
61 Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy. Blood 2011 2.69
62 microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J Exp Med 2010 2.68
63 Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell 2008 2.67
64 Ethics. The ISSCR guidelines for human embryonic stem cell research. Science 2007 2.62
65 CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis. Nature 2016 2.53
66 CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood 2008 2.52
67 Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev 2009 2.46
68 Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands. Dev Cell 2006 2.45
69 Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdiscip Rev Syst Biol Med 2010 2.38
70 New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell 2006 2.34
71 MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice. Cancer Cell 2003 2.33
72 Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation. Blood 2003 2.29
73 Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia. Cancer Res 2010 2.25
74 Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J Clin Invest 2002 2.22
75 Identification of mast cell progenitors in adult mice. Proc Natl Acad Sci U S A 2005 2.19
76 Circulation and chemotaxis of fetal hematopoietic stem cells. PLoS Biol 2004 2.18
77 Wnt-mediated self-renewal of neural stem/progenitor cells. Proc Natl Acad Sci U S A 2008 2.15
78 Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis. Proc Natl Acad Sci U S A 2007 2.13
79 Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages. Blood 2008 2.06
80 Gene expression analysis of purified hematopoietic stem cells and committed progenitors. Blood 2003 2.05
81 Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation. Proc Natl Acad Sci U S A 2009 2.02
82 Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat Biotechnol 2012 2.00
83 CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia. Proc Natl Acad Sci U S A 2007 1.99
84 Differential contribution of chemotaxis and substrate restriction to segregation of immature and mature thymocytes. Immunity 2009 1.96
85 Gene Expression Commons: an open platform for absolute gene expression profiling. PLoS One 2012 1.96
86 Stem cells are units of natural selection in a colonial ascidian. Cell 2005 1.95
87 The cancer stem cell hypothesis: a work in progress. Lab Invest 2006 1.87
88 The genome sequence of the colonial chordate, Botryllus schlosseri. Elife 2013 1.86
89 Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis. Blood 2008 1.86
90 Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma. Proc Natl Acad Sci U S A 2012 1.86
91 Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. Proc Natl Acad Sci U S A 2011 1.86
92 The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications. Curr Opin Immunol 2012 1.84
93 Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9. Blood 2003 1.84
94 Programmed cell removal: a new obstacle in the road to developing cancer. Nat Rev Cancer 2011 1.84
95 Cancer stem cell-directed therapies: recent data from the laboratory and clinic. Mol Ther 2008 1.83
96 Human neural stem cells induce functional myelination in mice with severe dysmyelination. Sci Transl Med 2012 1.82
97 MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. Proc Natl Acad Sci U S A 2010 1.82
98 Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proc Natl Acad Sci U S A 2007 1.81
99 In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors. Blood 2010 1.81
100 E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors. Proc Natl Acad Sci U S A 2009 1.81
101 Macrophages as mediators of tumor immunosurveillance. Trends Immunol 2010 1.80
102 Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors. Proc Natl Acad Sci U S A 2011 1.79
103 Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning. J Exp Med 2005 1.77
104 Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker. Proc Natl Acad Sci U S A 2011 1.71
105 Characterization of mouse clonogenic megakaryocyte progenitors. Proc Natl Acad Sci U S A 2002 1.70
106 Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. Blood 2008 1.70
107 Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle 2007 1.69
108 Differential gene expression profiling of adult murine hematopoietic stem cells. Blood 2002 1.69
109 Identification of a colonial chordate histocompatibility gene. Science 2013 1.68
110 Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response. Proc Natl Acad Sci U S A 2013 1.68
111 SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity. Mol Biol Cell 2008 1.66
112 Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction. PLoS One 2009 1.64
113 Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias. Proc Natl Acad Sci U S A 2003 1.64
114 Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes. Proc Natl Acad Sci U S A 2013 1.64
115 Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. Nat Commun 2012 1.63
116 Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation. J Immunol 2007 1.63
117 Hematopoietic cells maintain hematopoietic fates upon entering the brain. J Exp Med 2005 1.63
118 Niche recycling through division-independent egress of hematopoietic stem cells. J Exp Med 2009 1.62
119 Repeated, long-term cycling of putative stem cells between niches in a basal chordate. Dev Cell 2012 1.62
120 Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation. Cloning Stem Cells 2007 1.62
121 Three differentiation states risk-stratify bladder cancer into distinct subtypes. Proc Natl Acad Sci U S A 2012 1.60
122 Bmi-1-green fluorescent protein-knock-in mice reveal the dynamic regulation of bmi-1 expression in normal and leukemic hematopoietic cells. Stem Cells 2007 1.57
123 BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection. Blood 2013 1.57
124 A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983. J Immunol 2006 1.51
125 Lineage infidelity in myeloid cells with TCR gene rearrangement: a latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling. Proc Natl Acad Sci U S A 2002 1.49
126 Long-term outcome of patients with metastatic breast cancer treated with high-dose chemotherapy and transplantation of purified autologous hematopoietic stem cells. Biol Blood Marrow Transplant 2011 1.49
127 fester, A candidate allorecognition receptor from a primitive chordate. Immunity 2006 1.49
128 Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. PLoS One 2010 1.46
129 Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. 1982. J Immunol 2005 1.45
130 Identification of the earliest natural killer cell-committed progenitor in murine bone marrow. Blood 2011 1.45
131 Changes in integrin expression are associated with altered homing properties of Lin(-/lo)Thy1.1(lo)Sca-1(+)c-kit(+) hematopoietic stem cells following mobilization by cyclophosphamide/granulocyte colony-stimulating factor. Exp Hematol 2002 1.43
132 A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. J Immunol 2002 1.41
133 Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes. J Immunol 2007 1.41
134 Distinguishing mast cell and granulocyte differentiation at the single-cell level. Cell Stem Cell 2010 1.40
135 Hematopoietic stem cell aging: mechanism and consequence. Exp Gerontol 2007 1.39
136 Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature. Nat Cell Biol 2012 1.38
137 Pten, tumorigenesis, and stem cell self-renewal. Cell 2006 1.36
138 Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness. Head Neck 2011 1.35
139 Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration. Stem Cells 2004 1.35
140 The effect of bleeding on hematopoietic stem cell cycling and self-renewal. Stem Cells Dev 2007 1.33
141 Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell 2010 1.32
142 B-cell development fails in the absence of the Pbx1 proto-oncogene. Blood 2007 1.30
143 Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells. Nat Med 2003 1.28
144 VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration. Proc Natl Acad Sci U S A 2011 1.28
145 IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ. Nat Immunol 2010 1.27
146 Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis. Cell Stem Cell 2009 1.25
147 Evolution of a protochordate allorecognition locus. Science 2004 1.23
148 Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood 2002 1.21
149 Transcriptional instability is not a universal attribute of aging. Aging Cell 2007 1.21
150 Reversal of autoimmune disease in lupus-prone New Zealand black/New Zealand white mice by nonmyeloablative transplantation of purified allogeneic hematopoietic stem cells. Blood 2007 1.19
151 Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. Proc Natl Acad Sci U S A 2013 1.19
152 Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation. Blood 2003 1.19
153 Chronic versus acute myelogenous leukemia: a question of self-renewal. Cancer Cell 2004 1.18
154 Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors. Proc Natl Acad Sci U S A 2006 1.18
155 Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. Proc Natl Acad Sci U S A 2013 1.17
156 Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice. Diabetes 2003 1.17
157 Automated microfluidic chromatin immunoprecipitation from 2,000 cells. Lab Chip 2009 1.17
158 Frizzled 9 knock-out mice have abnormal B-cell development. Blood 2004 1.16
159 MiDReG: a method of mining developmentally regulated genes using Boolean implications. Proc Natl Acad Sci U S A 2010 1.15
160 In vivo directed differentiation of pluripotent stem cells for skeletal regeneration. Proc Natl Acad Sci U S A 2012 1.14
161 Cyclical generation and degeneration of organs in a colonial urochordate involves crosstalk between old and new: a model for development and regeneration. Dev Biol 2002 1.13
162 T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell. Proc Natl Acad Sci U S A 2010 1.13
163 Determinants of skeletal muscle contributions from circulating cells, bone marrow cells, and hematopoietic stem cells. Stem Cells 2004 1.11
164 Hematopoietic stem cells and the aging hematopoietic system. Semin Hematol 2008 1.11
165 Differential DNA damage response in stem and progenitor cells. Cell Stem Cell 2010 1.11
166 Initial characterization of a protochordate histocompatibility locus. Immunogenetics 2003 1.11
167 Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells. J Exp Med 2007 1.09
168 Macrophages are critical effectors of antibody therapies for cancer. MAbs 2015 1.09
169 In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood. Nat Protoc 2008 1.09
170 Hematopoietic stem cells: expression profiling and beyond. Stem Cell Rev 2006 1.08
171 Flk2+ myeloid progenitors are the main source of Langerhans cells. Blood 2005 1.07
172 Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips. Lab Chip 2014 1.07
173 Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury. Circulation 2005 1.07
174 Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150. Stem Cells 2009 1.06
175 Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal. Proc Natl Acad Sci U S A 2005 1.06
176 Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? Stem Cell Reports 2013 1.06
177 Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth. Proc Natl Acad Sci U S A 2013 1.06
178 Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome. Blood 2011 1.05
179 The adhesion molecule esam1 is a novel hematopoietic stem cell marker. Stem Cells 2009 1.05
180 Hematopoietic stem cell-derived pericytic cells in brain tumor angio-architecture. Stem Cells Dev 2008 1.04
181 Identification of the endostyle as a stem cell niche in a colonial chordate. Cell Stem Cell 2008 1.04
182 Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments. Blood 2011 1.03
183 Striving for normality: whole body regeneration through a series of abnormal generations. FASEB J 2007 1.00
184 Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations. Dev Biol 2003 1.00
185 Manganese-guided cellular MRI of human embryonic stem cell and human bone marrow stromal cell viability. Magn Reson Med 2009 1.00
186 Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen. Blood 2012 0.99
187 Effects of allogeneic contact on life-history traits of the colonial ascidian Botryllus schlosseri in Monterey Bay. Biol Bull 2003 0.98
188 Parabiosis in mice: a detailed protocol. J Vis Exp 2013 0.98
189 Self-renewal of the long-term reconstituting subset of hematopoietic stem cells is regulated by Ikaros. Stem Cells 2009 0.98
190 Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors. Exp Hematol 2005 0.98
191 Two-step oligoclonal development of male germ cells. Proc Natl Acad Sci U S A 2008 0.98
192 Brain tumor stem cell multipotency correlates with nanog expression and extent of passaging in human glioblastoma xenografts. Oncotarget 2013 0.96
193 Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role? Oncogene 2002 0.96
194 In vivo serial evaluation of superparamagnetic iron-oxide labeled stem cells by off-resonance positive contrast. Magn Reson Med 2008 0.96
195 Hematopoietic stem cells and other hematopoietic cells show broad resistance to chemotherapeutic agents in vivo when overexpressing bcl-2. Exp Hematol 2003 0.96
196 Intrathymic injection for analysis of T-cell progenitor activity. Methods Mol Med 2002 0.94
197 Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. J Thorac Cardiovasc Surg 2008 0.94
198 The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular development. Mol Cell Biol 2007 0.93
199 Enforced expression of Bcl-2 restores the number of NK cells, but does not rescue the impaired development of NKT cells or intraepithelial lymphocytes, in IL-2/IL-15 receptor beta-chain-deficient mice. J Immunol 2002 0.93
200 Stem cells: blood lines from embryo to adult. Nature 2007 0.93
201 Expression of AA4.1 marks lymphohematopoietic progenitors in early mouse development. Proc Natl Acad Sci U S A 2009 0.93
202 Differential expression of alpha2 integrin separates long-term and short-term reconstituting Lin-/loThy1.1(lo)c-kit+ Sca-1+ hematopoietic stem cells. Stem Cells 2005 0.93
203 Medicine: politic stem cells. Nature 2006 0.92
204 Telomerase maintained in self-renewing tissues during serial regeneration of the urochordate Botryllus schlosseri. Dev Biol 2004 0.92
205 Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors. Cell Cycle 2006 0.92
206 CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. J Clin Invest 2016 0.92
207 A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells. Neurosurgery 2009 0.91
208 Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes. J Immunol 2010 0.91
209 Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8. Proc Natl Acad Sci U S A 2014 0.90
210 Construction and characterization of large-insert genomic libraries (BAC and fosmid) from the Ascidian Botryllus schlosseri and initial physical mapping of a histocompatibility locus. Mar Biotechnol (NY) 2003 0.88
211 Differential amplification of murine bipotent megakaryocytic/erythroid progenitor and precursor cells during recovery from acute and chronic erythroid stress. Stem Cells 2005 0.88
212 Remodeling of endogenous mammary epithelium by breast cancer stem cells. Stem Cells 2012 0.88
213 Stepwise development of committed progenitors in the bone marrow that generate functional T cells in the absence of the thymus. J Immunol 2005 0.88
214 Hematopoietic stem and progenitor cells and the inflammatory response. Ann N Y Acad Sci 2009 0.87
215 The origin and fate of yolk sac hematopoiesis: application of chimera analyses to developmental studies. Int J Dev Biol 2010 0.87
216 Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation. Stem Cells Dev 2009 0.87
217 Space-time considerations for hematopoietic stem cell transplantation. Eur J Immunol 2008 0.87
218 Generation of a monoclonal antibody library against human embryonic stem cells. Methods Mol Biol 2007 0.84
219 Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification. Chem Commun (Camb) 2013 0.83
220 Flipping the script on macrophages in leiomyosarcoma. Oncoimmunology 2012 0.82
221 Early defect prethymic in bone marrow T cell progenitors in athymic nu/nu mice. J Immunol 2003 0.82
222 Identification of a novel gene involved in asexual organogenesis in the budding ascidian Botryllus schlosseri. Dev Dyn 2005 0.82
223 Purified hematopoietic stem cell transplantation: the next generation of blood and immune replacement. Immunol Allergy Clin North Am 2010 0.82
224 Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease? Vasc Med 2010 0.81
225 Perturbation of the hematopoietic system during embryonic liver development due to disruption of polyubiquitin gene Ubc in mice. PLoS One 2012 0.81
226 Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants. Oncoimmunology 2013 0.81
227 Telomerase activation and rejuvenation of telomere length in stimulated T cells derived from serially transplanted hematopoietic stem cells. J Exp Med 2002 0.81
228 Isolation of human fetal liver progenitors and their enhanced proliferation by three-dimensional coculture with endothelial cells. Tissue Eng Part A 2008 0.80
229 Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene. Autoimmunity 2004 0.80
230 Purified hematopoietic stem cell transplantation: the next generation of blood and immune replacement. Hematol Oncol Clin North Am 2011 0.80
231 The road to purified hematopoietic stem cell transplants is paved with antibodies. Curr Opin Immunol 2012 0.80
232 Immunogenicity of in vitro maintained and matured populations: potential barriers to engraftment of human pluripotent stem cell derivatives. Methods Mol Biol 2013 0.79
233 Stem cells in clinical practice. J Am Coll Surg 2003 0.78
234 Human acute myelogenous leukemia stem cells revisited: there's more than meets the eye. Cancer Cell 2011 0.78
235 The safety of embryonic stem cell therapy relies on teratoma removal. Oncotarget 2012 0.78
236 Live fibroblast harvest reveals surface marker shift in vitro. Tissue Eng Part C Methods 2014 0.78
237 Use of a KIT-specific monoclonal antibody to bypass imatinib resistance in gastrointestinal stromal tumors. Oncoimmunology 2013 0.77
238 Developmental plasticity of lymphoid progenitors. Semin Immunol 2002 0.77
239 Novel hematopoietic progenitor populations revealed by direct assessment of GATA1 protein expression and cMPL signaling events. Stem Cells 2011 0.77
240 Simple and efficient isolation of hematopoietic stem cells from H2K-zFP transgenic mice. Stem Cells 2005 0.76
241 Skeletal Stem Cell Niche Aberrancies Underlie Impaired Fracture Healing in a Mouse Model of Type 2 Diabetes. Plast Reconstr Surg 2015 0.76
242 Continuous development precludes radioprotection in a colonial ascidian. Dev Comp Immunol 2004 0.76
243 Enhanced survival of pluripotent stem cells under stressful conditions. Cell Cycle 2011 0.75
244 Neural Placode Tissue Derived From Myelomeningocele Repair Serves as a Viable Source of Oligodendrocyte Progenitor Cells. Neurosurgery 2015 0.75
245 Retroviral Transduction of FACS-Purified Hematopoietic Stem Cells. Methods Mol Med 2002 0.75
246 Abstract 140: identification, characterization, and prospective isolation of a fibroblast lineage contributing to dermal development, cutaneous scarring, radiation fibrosis, and cancer stroma. Plast Reconstr Surg 2014 0.75
247 Identification of human erythroid lineage-committed progenitors. Rinsho Ketsueki 2016 0.75
248 E. Donnall Thomas (1920-2012). Proc Natl Acad Sci U S A 2012 0.75
249 Did the molecules of adaptive immunity evolve from the innate immune system? Integr Comp Biol 2003 0.75