Published in Am J Clin Nutr on February 11, 2009
Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study. PLoS Med (2014) 2.22
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care (2010) 2.14
Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus. Hum Genet (2013) 1.48
Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience. Genet Epidemiol (2011) 1.29
Gene-environment and gene-treatment interactions in type 2 diabetes: progress, pitfalls, and prospects. Diabetes Care (2013) 1.20
Animal models of GWAS-identified type 2 diabetes genes. J Diabetes Res (2013) 1.01
Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes. Diabetologia (2012) 0.99
Diet, lifestyle, and genetic risk factors for type 2 diabetes: a review from the Nurses' Health Study, Nurses' Health Study 2, and Health Professionals' Follow-up Study. Curr Nutr Rep (2014) 0.95
TCF7L2 genetic variants modulate the effect of dietary fat intake on changes in body composition during a weight-loss intervention. Am J Clin Nutr (2012) 0.94
Interactions between genetic factors that predict diabetes and dietary factors that ultimately impact on risk of diabetes. Curr Opin Lipidol (2010) 0.94
Nutrigenomics in cardiovascular medicine. Circ Cardiovasc Genet (2009) 0.93
The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective. Cell Biosci (2012) 0.93
Mediterranean diet reduces the adverse effect of the TCF7L2-rs7903146 polymorphism on cardiovascular risk factors and stroke incidence: a randomized controlled trial in a high-cardiovascular-risk population. Diabetes Care (2013) 0.91
Genetics of type 2 diabetes in European populations. J Diabetes (2012) 0.89
Introduction to personalized medicine in diabetes mellitus. Rambam Maimonides Med J (2014) 0.85
Untangling the interplay of genetic and metabolic influences on beta-cell function: Examples of potential therapeutic implications involving TCF7L2 and FFAR1. Mol Metab (2014) 0.85
The role of the Wnt signaling pathway in incretin hormone production and function. Front Physiol (2012) 0.84
Interaction between the NOS3 gene and obesity as a determinant of risk of type 2 diabetes: the Atherosclerosis Risk in Communities study. PLoS One (2013) 0.80
Health effects of low-carbohydrate diets: where should new research go? Curr Diab Rep (2013) 0.79
Established BMI-associated genetic variants and their prospective associations with BMI and other cardiometabolic traits: the GLACIER Study. Int J Obes (Lond) (2016) 0.79
Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis. Nutrients (2014) 0.78
Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians. Am J Clin Nutr (2015) 0.76
Contribution of ENPP1, TCF7L2, and FTO polymorphisms to type 2 diabetes in mixed ancestry ethnic population of South Africa. Afr Health Sci (2015) 0.76
Genetic Risk Score of Nine Type 2 Diabetes Risk Variants that Interact with Erythrocyte Phospholipid Alpha-Linolenic Acid for Type 2 Diabetes in Chinese Hans: A Case-Control Study. Nutrients (2017) 0.75
The TCF7L2 rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population. BMC Genet (2014) 0.75
Interaction between genes and macronutrient intake on the risk of developing type 2 diabetes: systematic review and findings from European Prospective Investigation into Cancer (EPIC)-InterAct. Am J Clin Nutr (2017) 0.75
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care (1997) 49.11
Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol (1985) 26.13
Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet (1990) 19.91
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet (2006) 19.03
Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. National Diabetes Data Group. Diabetes (1979) 12.35
Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol (1989) 10.98
Validity of self-reported waist and hip circumferences in men and women. Epidemiology (1990) 10.57
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet (1998) 10.51
Reproducibility and validity of a self-administered physical activity questionnaire. Int J Epidemiol (1994) 9.90
Economic costs of diabetes in the US in 2002. Diabetes Care (2003) 8.92
Prospective study of alcohol consumption and risk of coronary disease in men. Lancet (1991) 8.64
The Nurses' Health Study: lifestyle and health among women. Nat Rev Cancer (2005) 8.19
The Nurses' Health Study: 20-year contribution to the understanding of health among women. J Womens Health (1997) 8.00
Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. Lancet (1991) 7.87
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med (2006) 7.75
Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr (1981) 7.49
Impact of overweight on the risk of developing common chronic diseases during a 10-year period. Arch Intern Med (2001) 7.07
Physical activity and television watching in relation to risk for type 2 diabetes mellitus in men. Arch Intern Med (2001) 6.23
The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. JAMA (2002) 6.05
Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland. Diabetologia (1992) 5.25
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest (2007) 5.02
Trends in the prevalence and ratio of diagnosed to undiagnosed diabetes according to obesity levels in the U.S. Diabetes Care (2004) 4.84
Dietary fiber, glycemic load, and risk of NIDDM in men. Diabetes Care (1997) 4.46
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. Diabetes (2006) 4.36
Glycemic index, glycemic load, and dietary fiber intake and incidence of type 2 diabetes in younger and middle-aged women. Am J Clin Nutr (2004) 4.29
International tables of glycemic index and glycemic load values: 2008. Diabetes Care (2008) 3.85
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms. Diabetologia (2007) 3.34
Diet and risk of Type II diabetes: the role of types of fat and carbohydrate. Diabetologia (2001) 2.91
Glycemic index, glycemic load, and risk of type 2 diabetes. Am J Clin Nutr (2002) 2.88
TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta. J Biol Chem (2004) 2.84
Whole-grain and fiber intake and the incidence of type 2 diabetes. Am J Clin Nutr (2003) 2.62
Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes (2006) 2.58
Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion. Diabetologia (2008) 2.57
Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men. Diabetes (2006) 2.45
Dietary glycemic load assessed by food-frequency questionnaire in relation to plasma high-density-lipoprotein cholesterol and fasting plasma triacylglycerols in postmenopausal women. Am J Clin Nutr (2001) 2.41
TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population. Diabetes (2007) 2.20
Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study. Diabetes (2007) 2.03
Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion. Diabetologia (2007) 1.97
Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans. Diabetes (2007) 1.79
Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes (2008) 1.78
Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent. Diabetologia (2007) 1.73
The new type 2 diabetes gene TCF7L2. Curr Opin Clin Nutr Metab Care (2007) 1.41
Metabolic effects of a low-glycemic-index diet. Am J Clin Nutr (1987) 1.18
Genetic variation at the adiponectin locus and risk of type 2 diabetes in women. Diabetes (2004) 1.11
Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men. Diabetologia (2007) 1.09
Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis. Am J Physiol Endocrinol Metab (2006) 1.03
The glycaemic index of foods containing sugars: comparison of foods with naturally-occurring v. added sugars. Br J Nutr (1995) 0.90
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Intake of sugar-sweetened beverages and weight gain: a systematic review. Am J Clin Nutr (2006) 13.19
Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med (2011) 12.29
Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA (2004) 11.69
Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA (2009) 11.52
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med (2003) 9.24
The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J Clin Endocrinol Metab (2007) 8.91
Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst (2004) 8.77
Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care (2010) 8.52
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Plasma adiponectin levels and risk of myocardial infarction in men. JAMA (2004) 7.46
Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring) (2008) 7.40
A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care (2003) 7.40
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance. Am J Clin Nutr (2002) 6.96
Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk. Circulation (2010) 6.86
Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am J Clin Nutr (2005) 6.67
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Powerful SNP-set analysis for case-control genome-wide association studies. Am J Hum Genet (2010) 6.60
Body-mass index and mortality among adults with incident type 2 diabetes. N Engl J Med (2014) 6.51
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet (2008) 6.22
A prospective study of sleep duration and mortality risk in women. Sleep (2004) 6.11
Sugar-sweetened beverages and genetic risk of obesity. N Engl J Med (2012) 5.98
Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ (2014) 5.88
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Performance of common genetic variants in breast-cancer risk models. N Engl J Med (2010) 5.79
Coffee consumption and risk for type 2 diabetes mellitus. Ann Intern Med (2004) 5.67
Correlates of long sleep duration. Sleep (2006) 5.67
Alternative dietary indices both strongly predict risk of chronic disease. J Nutr (2012) 5.60
Dairy consumption and risk of type 2 diabetes mellitus in men: a prospective study. Arch Intern Med (2005) 5.59
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality: sixteen years of follow-up in US women. Circulation (2008) 5.26
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol (2013) 5.24
Trends in cardiovascular health metrics and associations with all-cause and CVD mortality among US adults. JAMA (2012) 5.17
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation (2013) 5.02
Adherence to a DASH-style diet and risk of coronary heart disease and stroke in women. Arch Intern Med (2008) 4.98
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89
Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am J Clin Nutr (2010) 4.85
Quality control and quality assurance in genotypic data for genome-wide association studies. Genet Epidemiol (2010) 4.83
Depression and risk of stroke morbidity and mortality: a meta-analysis and systematic review. JAMA (2011) 4.75
ABO blood group and the risk of pancreatic cancer. J Natl Cancer Inst (2009) 4.72
Red meat consumption and mortality: results from 2 prospective cohort studies. Arch Intern Med (2012) 4.72
Exercise type and intensity in relation to coronary heart disease in men. JAMA (2002) 4.69
Physical activity of moderate intensity and risk of type 2 diabetes: a systematic review. Diabetes Care (2007) 4.63
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Vitamin D and calcium intake in relation to type 2 diabetes in women. Diabetes Care (2006) 4.62
Association between reduced sleep and weight gain in women. Am J Epidemiol (2006) 4.59
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57
Television viewing and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a meta-analysis. JAMA (2011) 4.54
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
Dietary fat and meat intake in relation to risk of type 2 diabetes in men. Diabetes Care (2002) 4.48
Pathway analysis by adaptive combination of P-values. Genet Epidemiol (2009) 4.48
Physical activity at midlife in relation to successful survival in women at age 70 years or older. Arch Intern Med (2010) 4.45
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. Nat Genet (2012) 4.41
Glycemic index, glycemic load, and dietary fiber intake and incidence of type 2 diabetes in younger and middle-aged women. Am J Clin Nutr (2004) 4.29
Dietary patterns, meat intake, and the risk of type 2 diabetes in women. Arch Intern Med (2004) 4.27
Sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men. Circulation (2012) 4.24
Sodium and potassium intake and mortality among US adults: prospective data from the Third National Health and Nutrition Examination Survey. Arch Intern Med (2011) 4.22
Dietary patterns and risk for type 2 diabetes mellitus in U.S. men. Ann Intern Med (2002) 4.19
The PhenX Toolkit: get the most from your measures. Am J Epidemiol (2011) 4.19
Low-carbohydrate-diet score and the risk of coronary heart disease in women. N Engl J Med (2006) 4.16
Coffee consumption and risk of type 2 diabetes: a systematic review. JAMA (2005) 4.14
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13