Published in Proc Natl Acad Sci U S A on August 07, 2009
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Gene-specific RNA polymerase II phosphorylation and the CTD code. Nat Struct Mol Biol (2010) 2.22
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Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation. EMBO J (2012) 1.55
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The histone modifications governing TFF1 transcription mediated by estrogen receptor. J Biol Chem (2011) 1.10
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TFIIH phosphorylation of the Pol II CTD stimulates mediator dissociation from the preinitiation complex and promoter escape. Mol Cell (2014) 1.07
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A dual interface determines the recognition of RNA polymerase II by RNA capping enzyme. J Biol Chem (2010) 0.93
Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover. Nucleic Acids Res (2011) 0.93
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Sub1 globally regulates RNA polymerase II C-terminal domain phosphorylation. Mol Cell Biol (2010) 0.91
Transcription inhibition as a therapeutic target for cancer. Cancers (Basel) (2011) 0.84
The Ess1 prolyl isomerase: traffic cop of the RNA polymerase II transcription cycle. Biochim Biophys Acta (2014) 0.84
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Gene looping facilitates TFIIH kinase-mediated termination of transcription. Sci Rep (2015) 0.80
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Inhibition of post-transcriptional RNA processing by CDK inhibitors and its implication in anti-viral therapy. PLoS One (2014) 0.78
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Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing. Mol Cell (2004) 5.01
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Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes. Mol Cell (2004) 3.26
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Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex. Mol Cell Biol (2003) 2.21
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PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. Mol Cell (2002) 5.59
Transcription regulation through promoter-proximal pausing of RNA polymerase II. Science (2008) 5.48
Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci. Cell (2008) 4.81
A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell (2011) 4.42
Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans. Nat Rev Genet (2012) 4.37
Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature (2009) 4.31
NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. Cell (2004) 4.21
Human zinc fingers as building blocks in the construction of artificial transcription factors. Nat Biotechnol (2003) 4.03
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature (2011) 3.90
Transcription factor and polymerase recruitment, modification, and movement on dhsp70 in vivo in the minutes following heat shock. Mol Cell Biol (2003) 3.65
Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells. Genes Dev (2011) 3.55
Mechanical disruption of individual nucleosomes reveals a reversible multistage release of DNA. Proc Natl Acad Sci U S A (2002) 3.52
Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes. Mol Cell (2004) 3.26
Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo. Science (2003) 3.22
PARP goes transcription. Cell (2003) 3.16
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell (2012) 2.81
The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila. Nature (2002) 2.77
High-resolution dynamic mapping of histone-DNA interactions in a nucleosome. Nat Struct Mol Biol (2009) 2.74
Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. Mol Cell Biol (2003) 2.70
Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS. Mol Cell (2005) 2.68
Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription. Science (2013) 2.66
Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior. Proc Natl Acad Sci U S A (2002) 2.53
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. Genes Dev (2010) 2.52
Precise maps of RNA polymerase reveal how promoters direct initiation and pausing. Science (2013) 2.51
Divergent transcription: a new feature of active promoters. Cell Cycle (2009) 2.50
Dynamics of heat shock factor association with native gene loci in living cells. Nature (2006) 2.45
X chromosome dosage compensation via enhanced transcriptional elongation in Drosophila. Nature (2011) 2.44
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell (2004) 2.27
Drosophila Paf1 modulates chromatin structure at actively transcribed genes. Mol Cell Biol (2006) 2.16
Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells. Mol Cell (2013) 2.13
Control of transcriptional elongation. Annu Rev Genet (2013) 1.92
Defining the status of RNA polymerase at promoters. Cell Rep (2012) 1.91
Specific contributions of histone tails and their acetylation to the mechanical stability of nucleosomes. J Mol Biol (2004) 1.87
Intranuclear distribution and local dynamics of RNA polymerase II during transcription activation. Mol Cell (2007) 1.87
Chromatin landscape dictates HSF binding to target DNA elements. PLoS Genet (2010) 1.82
P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo. Mol Cell Biol (2007) 1.81
The Drosophila BRM complex facilitates global transcription by RNA polymerase II. EMBO J (2002) 1.78
Spt6 enhances the elongation rate of RNA polymerase II in vivo. EMBO J (2009) 1.77
Tracking rates of transcription and splicing in vivo. Nat Struct Mol Biol (2009) 1.73
Heterogeneous coding of temporally discounted values in the dorsal and ventral striatum during intertemporal choice. Neuron (2011) 1.72
Identification of novel universal housekeeping genes by statistical analysis of microarray data. J Biochem Mol Biol (2007) 1.64
Probing SWI/SNF remodeling of the nucleosome by unzipping single DNA molecules. Nat Struct Mol Biol (2006) 1.58
Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation. Elife (2013) 1.51
Recruitment timing and dynamics of transcription factors at the Hsp70 loci in living cells. Mol Cell (2010) 1.50
Molecular mechanism of transcription inhibition by peptide antibiotic Microcin J25. Mol Cell (2004) 1.49
Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription. EMBO J (2011) 1.44
Extensive polymerase pausing during Drosophila axis patterning enables high-level and pliable transcription. Genes Dev (2013) 1.43
Cdk7 is required for full activation of Drosophila heat shock genes and RNA polymerase II phosphorylation in vivo. Mol Cell Biol (2003) 1.39
Genome-wide control of RNA polymerase II activity by cohesin. PLoS Genet (2013) 1.38
Activator-induced spread of poly(ADP-ribose) polymerase promotes nucleosome loss at Hsp70. Mol Cell (2011) 1.37
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation. Proc Natl Acad Sci U S A (2012) 1.35
The role of Bach2 in nucleic acid-triggered antiviral innate immune responses. Biochem Biophys Res Commun (2007) 1.34
Novel transcription coactivator complex containing activating signal cointegrator 1. Mol Cell Biol (2002) 1.29
Korean red ginseng (Panax ginseng) improves insulin sensitivity and attenuates the development of diabetes in Otsuka Long-Evans Tokushima fatty rats. Metabolism (2009) 1.22
Characterization of the interaction between neuronal RNA-binding protein HuD and AU-rich RNA. J Biol Chem (2003) 1.22
Structural and functional analyses of the major outer membrane protein of Chlamydia trachomatis. J Bacteriol (2007) 1.21
Overcoming the nucleosome barrier during transcript elongation. Trends Genet (2012) 1.19
Asymmetric shorter-duplex siRNA structures trigger efficient gene silencing with reduced nonspecific effects. Mol Ther (2009) 1.19
Specific SR protein-dependent splicing substrates identified through genomic SELEX. Nucleic Acids Res (2003) 1.18
Predeliberation activity in prefrontal cortex and striatum and the prediction of subsequent value judgment. Front Neurosci (2013) 1.16
Transcription through chromatin: understanding a complex FACT. Biochim Biophys Acta (2004) 1.15
Normal structure, variations, and anomalies of the pancreaticobiliary ducts of Koreans: a nationwide cooperative prospective study. Gastrointest Endosc (2002) 1.14
Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer. Hum Pathol (2011) 1.13
Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression. Proc Natl Acad Sci U S A (2011) 1.12
Over-expression of c-raf-1 proto-oncogene in liver cirrhosis and hepatocellular carcinoma. Hepatol Res (2004) 1.12
Accurate prediction of inducible transcription factor binding intensities in vivo. PLoS Genet (2012) 1.10
Interactions between subunits of Drosophila Mediator and activator proteins. Trends Biochem Sci (2005) 1.10
RNA aptamers directed to discrete functional sites on a single protein structural domain. Proc Natl Acad Sci U S A (2007) 1.10
Temporal discounting and inter-temporal choice in rhesus monkeys. Front Behav Neurosci (2009) 1.10
An RNA aptamer that interferes with the DNA binding of the HSF transcription activator. Nucleic Acids Res (2006) 1.10
Probing TBP interactions in transcription initiation and reinitiation with RNA aptamers that act in distinct modes. Proc Natl Acad Sci U S A (2004) 1.09
Mechanisms by which transcription factors gain access to target sequence elements in chromatin. Curr Opin Genet Dev (2012) 1.09
Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells. Carcinogenesis (2012) 1.07
Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation. Mol Endocrinol (2009) 1.06
Capecitabine combined with gemcitabine (CapGem) as first-line treatment in patients with advanced/metastatic biliary tract carcinoma. Cancer (2005) 1.06
Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target. J Mol Biol (2004) 1.06
Nucleic acid aptamers targeting cell-surface proteins. Methods (2011) 1.06
Discovery of a phosphatidylserine-recognizing peptide and its utility in molecular imaging of tumour apoptosis. J Cell Mol Med (2008) 1.03
The polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo. Mol Cell (2011) 1.02
Imaging transcription dynamics at endogenous genes in living Drosophila tissues. Methods (2008) 0.99
Indirect immunofluorescent labeling of Drosophila polytene chromosomes: visualizing protein interactions with chromatin in vivo. Methods Enzymol (2004) 0.99
Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor. Mol Endocrinol (2008) 0.99
Bifidus fermentation increases hypolipidemic and hypoglycemic effects of red ginseng. J Microbiol Biotechnol (2007) 0.98
Selection and elution of aptamers using nanoporous sol-gel arrays with integrated microheaters. Lab Chip (2009) 0.97
Chip-based detection of hepatitis C virus using RNA aptamers that specifically bind to HCV core antigen. Biochem Biophys Res Commun (2007) 0.96
Kinetics of promoter Pol II on Hsp70 reveal stable pausing and key insights into its regulation. Genes Dev (2014) 0.94
Inflexinol inhibits colon cancer cell growth through inhibition of nuclear factor-kappaB activity via direct interaction with p50. Mol Cancer Ther (2009) 0.93
Analysis of the effect of aging on the response to hypoxia by cDNA microarray. Mech Ageing Dev (2003) 0.92
RNA aptamers that functionally interact with green fluorescent protein and its derivatives. Nucleic Acids Res (2011) 0.92
Expression, purification and biochemical characterization of the N-terminal regions of human TIG3 and HRASLS3 proteins. Protein Expr Purif (2010) 0.92
Functional conservation of the glutamine-rich domains of yeast Gal11 and human SRC-1 in the transactivation of glucocorticoid receptor Tau 1 in Saccharomyces cerevisiae. Mol Cell Biol (2007) 0.92