Published in FEBS Lett on January 13, 2010
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The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons. Elife (2016) 0.78
Functional role of TRP channels in modulating ER stress and Autophagy. Cell Calcium (2016) 0.77
A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair. J Cell Biol (2016) 0.77
Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression. Oncotarget (2016) 0.77
Organelle biogenesis and interorganellar connections: Better in contact than in isolation. Commun Integr Biol (2014) 0.76
Inhibition of TRPML1 by lysosomal adenosine involved in severe combined immunodeficiency diseases. J Biol Chem (2017) 0.75
Regulation of mTORC1 by lysosomal calcium and calmodulin. Elife (2016) 0.75
Carboxyl-Terminal SSLKG Motif of the Human Cystinosin-LKG Plays an Important Role in Plasma Membrane Sorting. PLoS One (2016) 0.75
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TRPV3 mutants causing Olmsted Syndrome induce impaired cell adhesion and nonfunctional lysosomes. Channels (Austin) (2016) 0.75
N-butyldeoxynojirimycin delays motor deficits, cerebellar microgliosis, and Purkinje cell loss in a mouse model of mucolipidosis type IV. Neurobiol Dis (2017) 0.75
Patch-clamp technique to characterize ion channels in enlarged individual endolysosomes. Nat Protoc (2017) 0.75
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A gene network regulating lysosomal biogenesis and function. Science (2009) 7.17
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NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature (2009) 4.41
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TRPV1 shows dynamic ionic selectivity during agonist stimulation. Nat Neurosci (2008) 3.08
Identification of the gene causing mucolipidosis type IV. Nat Genet (2000) 2.87
The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel. Nature (2008) 2.76
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Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice. Proc Natl Acad Sci U S A (2007) 1.99
TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity. J Biol Chem (2005) 1.96
Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic. Traffic (2006) 1.92
A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse. Proc Natl Acad Sci U S A (2007) 1.91
Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1. J Biol Chem (2006) 1.90
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes. Traffic (2006) 1.84
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TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage. J Biol Chem (2005) 1.75
TRPM2 functions as a lysosomal Ca2+-release channel in beta cells. Sci Signal (2009) 1.71
Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells. Cell (2008) 1.69
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Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of rats. J Biol Chem (2007) 1.60
Lysosomes in iron metabolism, ageing and apoptosis. Histochem Cell Biol (2008) 1.60
Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype. J Biol Chem (2007) 1.56
The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration. Proc Natl Acad Sci U S A (2007) 1.51
A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype. EMBO J (2008) 1.47
Lysosomal exocytosis is impaired in mucolipidosis type IV. Mol Genet Metab (2006) 1.45
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Calcium: a fundamental regulator of intracellular membrane fusion? EMBO Rep (2007) 1.32
Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis. J Biol Chem (2009) 1.32
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Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway. FEBS Lett (2002) 1.31
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TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice. J Physiol (2008) 1.30
TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes. J Cell Mol Med (2008) 1.28
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TRPML cation channels regulate the specialized lysosomal compartment of vertebrate B-lymphocytes. Eur J Cell Biol (2006) 1.12
The calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathway. Traffic (2009) 1.12
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A potentially dynamic lysosomal role for the endogenous TRPML proteins. J Pathol (2009) 1.09
The tissue-specific expression of TRPML2 (MCOLN-2) gene is influenced by the presence of TRPML1. Pflugers Arch (2009) 1.04
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A role for calcium in stabilizing transport vesicle coats. J Biol Chem (2001) 1.03
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Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. J Neurosci (2004) 2.41
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes. Cell (2012) 2.35
TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation. Cell (2010) 2.32
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB. Nat Cell Biol (2015) 1.88
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A superfamily of voltage-gated sodium channels in bacteria. J Biol Chem (2003) 1.84
TRP ion channels in the nervous system. Curr Opin Neurobiol (2004) 1.78
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The channel kinase, TRPM7, is required for early embryonic development. Proc Natl Acad Sci U S A (2011) 1.29
The voltage-gated Na+ channel NaVBP has a role in motility, chemotaxis, and pH homeostasis of an alkaliphilic Bacillus. Proc Natl Acad Sci U S A (2004) 1.28
Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics. Proc Natl Acad Sci U S A (2013) 1.09
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