Published in Curr Opin Genet Dev on February 12, 2010
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. Proc Natl Acad Sci U S A (2010) 4.73
ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression. Nature (2014) 2.24
The double face of the histone variant H3.3. Cell Res (2011) 2.00
Genome-wide incorporation dynamics reveal distinct categories of turnover for the histone variant H3.3. Genome Biol (2013) 1.77
Every amino acid matters: essential contributions of histone variants to mammalian development and disease. Nat Rev Genet (2014) 1.62
H3.3 is deposited at centromeres in S phase as a placeholder for newly assembled CENP-A in G₁ phase. Nucleus (2011) 1.57
Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa. Nat Struct Mol Biol (2013) 1.54
Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer. Nat Rev Genet (2013) 1.53
Genetic code expansion in stable cell lines enables encoded chromatin modification. Nat Methods (2016) 1.50
Xenopus HJURP and condensin II are required for CENP-A assembly. J Cell Biol (2011) 1.29
Genome-wide analysis of histone H3.1 and H3.3 variants in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2012) 1.27
The activity-dependent histone variant H2BE modulates the life span of olfactory neurons. Elife (2012) 1.26
Snf2-family proteins: chromatin remodellers for any occasion. Curr Opin Chem Biol (2011) 1.23
Chromatin and DNA replication. Cold Spring Harb Perspect Biol (2013) 1.22
Histone variants: emerging players in cancer biology. Cell Mol Life Sci (2013) 1.17
Myogenic transcriptional activation of MyoD mediated by replication-independent histone deposition. Proc Natl Acad Sci U S A (2010) 1.14
Dynamic deposition of histone variant H3.3 accompanies developmental remodeling of the Arabidopsis transcriptome. PLoS Genet (2012) 1.11
Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma. Nat Rev Cancer (2014) 1.10
Towards a mechanism for histone chaperones. Biochim Biophys Acta (2014) 1.06
Nucleosome-depleted chromatin gaps recruit assembly factors for the H3.3 histone variant. Proc Natl Acad Sci U S A (2012) 1.05
The Histone Database: an integrated resource for histones and histone fold-containing proteins. Database (Oxford) (2011) 1.04
Comparative transcriptional profiling of the axolotl limb identifies a tripartite regeneration-specific gene program. PLoS One (2013) 1.04
A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast. PLoS Genet (2012) 1.02
Single-cell analysis of Daxx and ATRX-dependent transcriptional repression. J Cell Sci (2012) 1.02
Probabilistic inference for nucleosome positioning with MNase-based or sonicated short-read data. PLoS One (2012) 1.00
Short-term memory of danger signals and environmental stimuli in immune cells. Nat Immunol (2013) 0.99
ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes. Cell Rep (2015) 0.99
Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly. Genes Dev (2011) 0.98
Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation. Nat Commun (2015) 0.96
Drosophila Yemanuclein and HIRA cooperate for de novo assembly of H3.3-containing nucleosomes in the male pronucleus. PLoS Genet (2013) 0.93
Four amino acids guide the assembly or disassembly of Arabidopsis histone H3.3-containing nucleosomes. Proc Natl Acad Sci U S A (2011) 0.92
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation. Proc Natl Acad Sci U S A (2013) 0.91
Histone H3.3 maintains genome integrity during mammalian development. Genes Dev (2015) 0.91
The PML-Interacting Protein DAXX: Histone Loading Gets into the Picture. Front Oncol (2013) 0.91
WHSC1 links transcription elongation to HIRA-mediated histone H3.3 deposition. EMBO J (2013) 0.89
Dissecting the roles of the histone chaperones reveals the evolutionary conserved mechanism of transcription-coupled deposition of H3.3. Nucleic Acids Res (2013) 0.87
Replication-uncoupled histone deposition during adenovirus DNA replication. J Virol (2012) 0.87
The Fork in the Road: Histone Partitioning During DNA Replication. Genes (Basel) (2015) 0.87
The genetic and epigenetic journey of embryonic stem cells into mature neural cells. Front Genet (2012) 0.87
Human histone acetyltransferase 1 protein preferentially acetylates H4 histone molecules in H3.1-H4 over H3.3-H4. J Biol Chem (2012) 0.86
Dualistic function of Daxx at centromeric and pericentromeric heterochromatin in normal and stress conditions. Nucleus (2012) 0.84
Arabidopsis replacement histone variant H3.3 occupies promoters of regulated genes. Genome Biol (2014) 0.81
Parallel gateways to pluripotency: open chromatin in stem cells and development. Curr Opin Genet Dev (2010) 0.81
Dynamic acetylation of lysine-4-trimethylated histone H3 and H3 variant biology in a simple multicellular eukaryote. Nucleic Acids Res (2012) 0.81
Transcription factor EKLF (KLF1) recruitment of the histone chaperone HIRA is essential for β-globin gene expression. Proc Natl Acad Sci U S A (2014) 0.81
The genetic signatures of pediatric high-grade glioma: no longer a one-act play. Semin Radiat Oncol (2014) 0.80
Mutations in chromatin machinery and pediatric high-grade glioma. Sci Adv (2016) 0.80
A Potential New Mechanism of Arsenic Carcinogenesis: Depletion of Stem-Loop Binding Protein and Increase in Polyadenylated Canonical Histone H3.1 mRNA. Biol Trace Elem Res (2015) 0.80
Introduction--Epiphanies in epigenetics. Prog Mol Biol Transl Sci (2011) 0.79
Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3. Mol Biol Cell (2015) 0.79
Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum". ACS Chem Biol (2015) 0.78
Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site. J Biol Chem (2013) 0.78
Genome-wide analysis of H3.3 dissociation reveals high nucleosome turnover at distal regulatory regions of embryonic stem cells. Epigenetics Chromatin (2014) 0.77
PP1α, PP1β and Wip-1 regulate H4S47 phosphorylation and deposition of histone H3 variant H3.3. Nucleic Acids Res (2013) 0.77
Histone storage and deposition in the early Drosophila embryo. Chromosoma (2015) 0.77
Gene expression studies for the analysis of domoic acid production in the marine diatom Pseudo-nitzschia multiseries. BMC Mol Biol (2013) 0.77
Molecular turnover, the H3.3 dilemma and organismal aging (hypothesis). Aging Cell (2015) 0.77
Structure and function of human histone H3.Y nucleosome. Nucleic Acids Res (2016) 0.76
Identification of a replication-independent replacement histone H3 in the basidiomycete Ustilago maydis. J Biol Chem (2011) 0.76
Pleiotropic Functions of H3K27Me3 Demethylases in Immune Cell Differentiation. Trends Immunol (2016) 0.76
Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis. Epigenetics Chromatin (2016) 0.76
Recognizing methylated histone variant H3.3 to prevent tumors. Cell Res (2014) 0.76
The cnidarian Hydractinia echinata employs canonical and highly adapted histones to pack its DNA. Epigenetics Chromatin (2016) 0.75
Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets. Curr Neuropharmacol (2017) 0.75
Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Exp Mol Med (2016) 0.75
Analysis of Histones H3 and H4 Reveals Novel and Conserved Post-Translational Modifications in Sugarcane. PLoS One (2015) 0.75
H3.3 demarcates GC-rich coding and subtelomeric regions and serves as potential memory mark for virulence gene expression in Plasmodium falciparum. Sci Rep (2016) 0.75
O-linked N-acetylglucosamine transferase (OGT) interacts with the histone chaperone HIRA complex and regulates nucleosome assembly and cellular senescence. Proc Natl Acad Sci U S A (2016) 0.75
Investigation of the human H3.3B (H3F3B) gene expression as a novel marker in patients with colorectal cancer. J Gastrointest Oncol (2017) 0.75
Unusual DNA packaging characteristics in endoreduplicated Caenorhabditis elegans oocytes defined by in vivo accessibility to an endogenous nuclease activity. Epigenetics Chromatin (2013) 0.75
The Histone Variant H3.3 Is Enriched at Drosophila Amplicon Origins but Does Not Mark Them for Activation. G3 (Bethesda) (2016) 0.75
Canonical and variant forms of histone H3 are deposited onto the human cytomegalovirus genome during lytic and latent infections. J Virol (2016) 0.75
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell (2004) 10.16
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell (2002) 9.80
Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (2010) 8.79
From silencing to gene expression: real-time analysis in single cells. Cell (2004) 7.73
Dynamics of replication-independent histone turnover in budding yeast. Science (2007) 6.41
A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell (2009) 6.26
H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions. Nat Genet (2009) 5.82
Histone H3.3 is enriched in covalent modifications associated with active chromatin. Proc Natl Acad Sci U S A (2004) 4.88
Non-allelic variants of histones 2a, 2b and 3 in mammals. Nature (1977) 4.19
Histone replacement marks the boundaries of cis-regulatory domains. Science (2007) 4.06
A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones. J Cell Biol (1987) 3.92
Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei. Genes Dev (2009) 3.62
Genome-wide replication-independent histone H3 exchange occurs predominantly at promoters and implicates H3 K56 acetylation and Asf1. Mol Cell (2007) 3.60
Transcriptional activation triggers deposition and removal of the histone variant H3.3. Genes Dev (2005) 3.57
HIRA is critical for a nucleosome assembly pathway independent of DNA synthesis. Mol Cell (2002) 3.44
Evidence that Spt6p controls chromatin structure by a direct interaction with histones. Science (1996) 3.23
The human and mouse replication-dependent histone genes. Genomics (2002) 3.23
PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state. Mol Cell (2006) 3.20
Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol (2001) 3.14
Transcriptional activators are dispensable for transcription in the absence of Spt6-mediated chromatin reassembly of promoter regions. Mol Cell (2006) 2.98
Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps. Mol Cell Biol (1991) 2.94
CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo. Science (2007) 2.71
Continuous histone H2B and transcription-dependent histone H3 exchange in yeast cells outside of replication. Mol Cell (2007) 2.59
Molecular dissection of formation of senescence-associated heterochromatin foci. Mol Cell Biol (2007) 2.56
Formation of the 3' end of histone mRNA. Gene (1999) 2.55
Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics (2002) 2.54
Histone variants specific to the transcriptionally active, amitotically dividing macronucleus of the unicellular eucaryote, Tetrahymena thermophila. Cell (1980) 2.52
Replication-independent histone deposition by the HIR complex and Asf1. Curr Biol (2005) 2.40
Variant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias. Genes Dev (2005) 2.26
Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos. Int J Dev Biol (2006) 2.17
Variant histone H3.3 marks promoters of transcriptionally active genes during mammalian cell division. EMBO Rep (2005) 2.12
Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells. Genome Res (2009) 2.08
Patterns of histone variant synthesis can distinguish G0 from G1 cells. Cell (1982) 2.08
Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol (1993) 1.96
Chromosome-wide nucleosome replacement and H3.3 incorporation during mammalian meiotic sex chromosome inactivation. Nat Genet (2007) 1.93
Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A (2005) 1.91
Histone chaperone spt16 promotes redeposition of the original h3-h4 histones evicted by elongating RNA polymerase. Mol Cell (2009) 1.66
Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality. Mol Cell Biol (2002) 1.66
Drosophila GAGA factor directs histone H3.3 replacement that prevents the heterochromatin spreading. Genes Dev (2007) 1.66
The histone chaperone Asf1p mediates global chromatin disassembly in vivo. J Biol Chem (2004) 1.61
The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev (2005) 1.57
Histones are incorporated in trans during reassembly of the yeast PHO5 promoter. Mol Cell (2005) 1.52
The essential role of Drosophila HIRA for de novo assembly of paternal chromatin at fertilization. PLoS Genet (2007) 1.50
Molecular evolution of the nontandemly repeated genes of the histone 3 multigene family. Mol Biol Evol (2002) 1.50
The histone variant H3.3 regulates gene expression during lytic infection with herpes simplex virus type 1. J Virol (2008) 1.48
Histone H1 binding is inhibited by histone variant H3.3. EMBO J (2009) 1.47
Histone dynamics in living cells revealed by photobleaching. DNA Repair (Amst) (2005) 1.43
Histone H3.3 variant dynamics in the germline of Caenorhabditis elegans. PLoS Genet (2006) 1.42
Sin mutations alter inherent nucleosome mobility. EMBO J (2004) 1.37
Inducible deposition of the histone variant H3.3 in interferon-stimulated genes. J Biol Chem (2009) 1.36
Dynamic histone variant exchange accompanies gene induction in T cells. Mol Cell Biol (2009) 1.31
Histone H3.3 deposition at E2F-regulated genes is linked to transcription. EMBO Rep (2006) 1.29
The Schizosaccharomyces pombe HIRA-like protein Hip1 is required for the periodic expression of histone genes and contributes to the function of complex centromeres. Mol Cell Biol (2004) 1.28
The fission yeast HIRA histone chaperone is required for promoter silencing and the suppression of cryptic antisense transcripts. Mol Cell Biol (2009) 1.25
Two-color cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in histone gene repression. Mol Cell (2009) 1.24
Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells. Mol Cell Biol (2008) 1.23
A retroviral gene trap insertion into the histone 3.3A gene causes partial neonatal lethality, stunted growth, neuromuscular deficits and male sub-fertility in transgenic mice. Hum Mol Genet (1999) 1.23
H2A.Z and H3.3 histone variants affect nucleosome structure: biochemical and biophysical studies. Biochemistry (2009) 1.19
Histone chaperones regulate histone exchange during transcription. EMBO J (2007) 1.18
Dynamic regulation of replication independent deposition of histone H3 in fission yeast. Nucleic Acids Res (2005) 1.16
Differential regulation of repeated histone genes during the fission yeast cell cycle. Nucleic Acids Res (2007) 1.11
SWI/SNF and Asf1p cooperate to displace histones during induction of the saccharomyces cerevisiae HO promoter. Mol Cell Biol (2009) 1.04
Epigenetic and replacement roles of histone variant H3.3 in reproduction and development. Int J Dev Biol (2009) 0.99
Two types of polyadenated mRNAs are synthesized from Drosophila replication-dependent histone genes. Eur J Biochem (1997) 0.91
Potential role of the histone chaperone, CAF-1, in transcription. BMB Rep (2009) 0.86
Chromatin: sub out the replacement. Curr Biol (2009) 0.80
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature (2007) 11.14
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature (2006) 10.73
Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol Cell (2007) 9.73
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature (2007) 9.25
WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell (2005) 8.86
Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (2010) 8.79
Histone and chromatin cross-talk. Curr Opin Cell Biol (2003) 8.69
Epigenetics: a landscape takes shape. Cell (2007) 8.29
MLL targets SET domain methyltransferase activity to Hox gene promoters. Mol Cell (2002) 8.17
Multivalent engagement of chromatin modifications by linked binding modules. Nat Rev Mol Cell Biol (2007) 8.14
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev (2003) 7.91
Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature (2006) 7.70
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature (2002) 7.54
Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell (2003) 6.44
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (2013) 6.29
Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer (2010) 6.27
Extraction, purification and analysis of histones. Nat Protoc (2007) 6.25
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell (2005) 6.12
Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol (2006) 6.03
Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. Mol Cell Biol (2006) 5.99
Epigenetic dynamics of imprinted X inactivation during early mouse development. Science (2003) 5.80
RNA meets chromatin. Genes Dev (2005) 5.66
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. Mol Cell (2002) 5.59
Human PAD4 regulates histone arginine methylation levels via demethylimination. Science (2004) 5.46
Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev (2002) 5.43
Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol (2002) 5.42
New nomenclature for chromatin-modifying enzymes. Cell (2007) 5.34
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol (2009) 5.27
Binary switches and modification cassettes in histone biology and beyond. Nature (2003) 4.75
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. Proc Natl Acad Sci U S A (2010) 4.73
Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa. Nat Genet (2003) 4.56
Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol Cell Biol (2002) 4.50
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell (2003) 4.13
Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell (2006) 3.87
Organismal differences in post-translational modifications in histones H3 and H4. J Biol Chem (2006) 3.84
Gene silencing: trans-histone regulatory pathway in chromatin. Nature (2002) 3.77
Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes. Nat Genet (2001) 3.63
Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes. Genes Dev (2002) 3.37
Decoding the epigenetic language of neuronal plasticity. Neuron (2008) 3.23
Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena. Cell (2002) 3.16
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature (2009) 3.13
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09
Expression patterns and post-translational modifications associated with mammalian histone H3 variants. J Biol Chem (2005) 3.00
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia. PLoS Genet (2012) 2.94
WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity. Nature (2008) 2.86
Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation. Genes Dev (2007) 2.81
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell (2011) 2.68
Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis". Proc Natl Acad Sci U S A (2006) 2.68
ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours. Nature (2010) 2.65
Chromatin remodeling and cancer, Part I: Covalent histone modifications. Trends Mol Med (2007) 2.60
Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription. J Biol Chem (2003) 2.48
Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger. Mol Cell (2007) 2.47
Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell (2010) 2.44
Evidence that Set1, a factor required for methylation of histone H3, regulates rDNA silencing in S. cerevisiae by a Sir2-independent mechanism. Curr Biol (2002) 2.44
Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43
Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome. Mol Cell Biol (2004) 2.43
KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors. Cell (2013) 2.34
PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks. Mutat Res (2008) 2.31
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat Struct Mol Biol (2006) 2.29
RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev (2007) 2.26
Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis. Mol Cell (2010) 2.25
The nucleation and maintenance of heterochromatin by a histone deacetylase in fission yeast. Mol Cell (2005) 2.19
ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nat Struct Mol Biol (2011) 2.18
Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc Natl Acad Sci U S A (2003) 2.16
Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae. Cell (2005) 2.15
Histone arginine methylation and its dynamic regulation. Front Biosci (2006) 2.06
Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Mol Cell Biol (2008) 2.05
Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. Genes Dev (2006) 2.05
Operating on chromatin, a colorful language where context matters. J Mol Biol (2011) 2.00
Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A (2005) 1.91
Proteome-wide prediction of acetylation substrates. Proc Natl Acad Sci U S A (2009) 1.81
Polycomb Group proteins: an evolutionary perspective. Trends Genet (2007) 1.79
Cancer. New epigenetic drivers of cancers. Science (2011) 1.73
Histone H2B deacetylation at lysine 11 is required for yeast apoptosis induced by phosphorylation of H2B at serine 10. Mol Cell (2006) 1.72
Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons. J Cell Sci (2003) 1.70
Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration. Proc Natl Acad Sci U S A (2010) 1.68
DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition. Nature (2012) 1.65
Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes. Proc Natl Acad Sci U S A (2011) 1.65
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. Mol Cell Biol (2002) 1.63
Chromatin remodeling and cancer, Part II: ATP-dependent chromatin remodeling. Trends Mol Med (2007) 1.59
Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity. Genes Dev (2008) 1.51
Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. J Biol Chem (2006) 1.50
Phosphorylation of histone H2B at DNA double-strand breaks. J Exp Med (2004) 1.49
The enhancement of histone H4 and H2A serine 1 phosphorylation during mitosis and S-phase is evolutionarily conserved. Chromosoma (2004) 1.47
Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis. Proc Natl Acad Sci U S A (2002) 1.46
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Mol Cell (2012) 1.43
Histone variants in metazoan development. Dev Cell (2010) 1.42
Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae. Curr Biol (2005) 1.41
Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent. J Biol Chem (2009) 1.38
Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA). Proc Natl Acad Sci U S A (2002) 1.35
Taking LSD 1 to a new high. Cell (2005) 1.34
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Cancer Discov (2012) 1.33
Histone regulation in the CNS: basic principles of epigenetic plasticity. Neuropsychopharmacology (2012) 1.33
Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry. J Proteome Res (2004) 1.33
Dynamic alterations of specific histone modifications during early murine development. J Cell Sci (2004) 1.30
Modifications of human histone H3 variants during mitosis. Biochemistry (2005) 1.29
Analysis of histones in Xenopus laevis. I. A distinct index of enriched variants and modifications exists in each cell type and is remodeled during developmental transitions. J Biol Chem (2008) 1.26
Comprehensive phosphoprotein analysis of linker histone H1 from Tetrahymena thermophila. Mol Cell Proteomics (2006) 1.26
Beyond the double helix: writing and reading the histone code. Novartis Found Symp (2004) 1.25