Published in EMBO J on April 20, 2010
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Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene. Cell (2010) 1.46
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CHD chromatin remodelers and the transcription cycle. Transcription (2011) 0.94
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CTCF regulates Kaposi's sarcoma-associated herpesvirus latency transcription by nucleosome displacement and RNA polymerase programming. J Virol (2012) 0.90
Exon 11 skipping of E-cadherin RNA downregulates its expression in head and neck cancer cells. Mol Cancer Ther (2011) 0.89
Physical properties of naked DNA influence nucleosome positioning and correlate with transcription start and termination sites in yeast. BMC Genomics (2011) 0.89
E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors. BMC Cancer (2013) 0.88
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Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development. Mol Cell Biol (2011) 0.86
POF regulates the expression of genes on the fourth chromosome in Drosophila melanogaster by binding to nascent RNA. Mol Cell Biol (2012) 0.86
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Alternative splicing switching in stem cell lineages. Front Biol (Beijing) (2013) 0.82
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New insights into the expression and functions of the Kaposi's sarcoma-associated herpesvirus long noncoding PAN RNA. Virus Res (2015) 0.78
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Yeast pheromone receptor genes STE2 and STE3 are differently regulated at the transcription and polyadenylation level. Proc Natl Acad Sci U S A (2011) 0.77
The WD40-repeat proteins NFC101 and NFC102 regulate different aspects of maize development through chromatin modification. Plant Cell (2013) 0.77
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Adaptive thermal control of stem gravitropism through alternative RNA splicing in Arabidopsis. Plant Signal Behav (2015) 0.75
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Hidden dangers: a cryptic exon disrupts BRCA2 mRNA. Clin Cancer Res (2012) 0.75
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Expansion of the eukaryotic proteome by alternative splicing. Nature (2010) 8.84
Differential chromatin marking of introns and expressed exons by H3K36me3. Nat Genet (2009) 8.11
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Splicing in disease: disruption of the splicing code and the decoding machinery. Nat Rev Genet (2007) 7.42
The human SWI/SNF subunit Brm is a regulator of alternative splicing. Nat Struct Mol Biol (2005) 6.60
The SR protein family of splicing factors: master regulators of gene expression. Biochem J (2009) 5.98
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A slow RNA polymerase II affects alternative splicing in vivo. Mol Cell (2003) 5.82
Nucleosome positions predicted through comparative genomics. Nat Genet (2006) 5.81
Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Mol Cell (2007) 5.78
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Multiple links between transcription and splicing. RNA (2004) 4.90
A computational analysis of sequence features involved in recognition of short introns. Proc Natl Acad Sci U S A (2001) 4.68
Histone variants--ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol (2010) 4.45
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Nucleosomes are well positioned in exons and carry characteristic histone modifications. Genome Res (2009) 3.95
How did alternative splicing evolve? Nat Rev Genet (2004) 3.88
The splicing factor SC35 has an active role in transcriptional elongation. Nat Struct Mol Biol (2008) 3.86
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation. EMBO J (2007) 3.81
Biased chromatin signatures around polyadenylation sites and exons. Mol Cell (2009) 3.74
DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation. Cell (2009) 3.66
The logic of chromatin architecture and remodelling at promoters. Nature (2009) 3.63
Discovery and annotation of functional chromatin signatures in the human genome. PLoS Comput Biol (2009) 3.61
Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II. Science (2009) 3.60
Control of alternative splicing through siRNA-mediated transcriptional gene silencing. Nat Struct Mol Biol (2009) 3.47
Rates of in situ transcription and splicing in large human genes. Nat Struct Mol Biol (2009) 3.39
On the importance of being co-transcriptional. J Cell Sci (2002) 3.37
"Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions. Mol Cell (2009) 3.28
Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells. Nat Struct Mol Biol (2006) 3.21
What controls nucleosome positions? Trends Genet (2009) 3.15
Chromatin-associated periodicity in genetic variation downstream of transcriptional start sites. Science (2008) 3.10
High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Genome Res (2009) 3.08
The role of DNA methylation in setting up chromatin structure during development. Nat Genet (2003) 3.06
G+C content dominates intrinsic nucleosome occupancy. BMC Bioinformatics (2009) 3.05
SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. Mol Cell (2007) 3.04
Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing. Proc Natl Acad Sci U S A (2009) 2.94
RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20. Nat Struct Mol Biol (2006) 2.81
The human dystrophin gene requires 16 hours to be transcribed and is cotranscriptionally spliced. Nat Genet (1995) 2.76
Transcriptional activators differ in their abilities to control alternative splicing. J Biol Chem (2002) 2.56
Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science (2002) 2.53
Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns. PLoS Biol (2006) 2.51
Exon tethering in transcription by RNA polymerase II. Mol Cell (2006) 2.47
Chromatin, transcript elongation and alternative splicing. Nat Struct Mol Biol (2006) 2.35
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Co-transcriptional splicing of constitutive and alternative exons. RNA (2009) 2.29
Nucleosomes are preferentially positioned at exons in somatic and sperm cells. Cell Cycle (2009) 2.29
Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. EMBO J (2007) 2.19
A wave of nascent transcription on activated human genes. Proc Natl Acad Sci U S A (2009) 2.18
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Splicing precedes polyadenylation during Drosophila E74A transcription. Mol Cell Biol (1990) 1.99
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A 5' splice site enhances the recruitment of basal transcription initiation factors in vivo. Mol Cell (2008) 1.74
A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional. Mol Cell (2006) 1.71
RNA polymerase II carboxy-terminal domain phosphorylation is required for cotranscriptional pre-mRNA splicing and 3'-end formation. Mol Cell Biol (2004) 1.68
DNA methylation increases nucleosome compaction and rigidity. J Am Chem Soc (2010) 1.67
A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. Genes Dev (2005) 1.66
The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1. Mol Cell Biol (2001) 1.64
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RNA polymerase II conducts a symphony of pre-mRNA processing activities. Biochim Biophys Acta (2002) 1.61
A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3' end processing. EMBO J (2003) 1.50
Splice-site pairing is an intrinsically high fidelity process. Proc Natl Acad Sci U S A (2009) 1.44
Evolutionary footprints of nucleosome positions in yeast. Trends Genet (2008) 1.43
Coactivator-associated arginine methyltransferase 1, CARM1, affects pre-mRNA splicing in an isoform-specific manner. J Biol Chem (2005) 1.42
A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast. Mol Cell (2008) 1.36
Acetylation by the transcriptional coactivator Gcn5 plays a novel role in co-transcriptional spliceosome assembly. PLoS Genet (2009) 1.35
Bending and flexibility of methylated and unmethylated EcoRI DNA. J Mol Biol (2002) 1.35
Gene splice sites correlate with nucleosome positions. Gene (2005) 1.31
Histone H3 K36 methylation is mediated by a trans-histone methylation pathway involving an interaction between Set2 and histone H4. Genes Dev (2008) 1.28
The CTD role in cotranscriptional RNA processing and surveillance. FEBS Lett (2008) 1.27
Alu exonization events reveal features required for precise recognition of exons by the splicing machinery. PLoS Comput Biol (2009) 1.20
SR proteins: a foot on the exon before the transition from intron to exon definition. Trends Genet (2006) 1.15
The organization of nucleosomes around splice sites. Nucleic Acids Res (2010) 0.90
Chromatin organization marks exon-intron structure. Nat Struct Mol Biol (2009) 5.90
Alu-containing exons are alternatively spliced. Genome Res (2002) 5.45
The birth of an alternatively spliced exon: 3' splice-site selection in Alu exons. Science (2003) 5.04
Intronic sequences flanking alternatively spliced exons are conserved between human and mouse. Genome Res (2003) 5.01
Alternative splicing and evolution: diversification, exon definition and function. Nat Rev Genet (2010) 4.30
Comparative analysis identifies exonic splicing regulatory sequences--The complex definition of enhancers and silencers. Mol Cell (2006) 4.11
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Different levels of alternative splicing among eukaryotes. Nucleic Acids Res (2006) 3.07
Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome. Genome Biol (2007) 2.35
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB. Nat Struct Mol Biol (2010) 2.19
A non-EST-based method for exon-skipping prediction. Genome Res (2004) 2.15
Alternative splicing: current perspectives. Bioessays (2008) 1.95
Minimal conditions for exonization of intronic sequences: 5' splice site formation in alu exons. Mol Cell (2004) 1.93
Comparative analysis detects dependencies among the 5' splice-site positions. RNA (2004) 1.91
Detection and removal of biases in the analysis of next-generation sequencing reads. PLoS One (2011) 1.91
Large-scale comparative analysis of splicing signals and their corresponding splicing factors in eukaryotes. Genome Res (2007) 1.86
Insights into the connection between cancer and alternative splicing. Trends Genet (2007) 1.78
RNA-editing-mediated exon evolution. Genome Biol (2007) 1.77
Human-mouse comparative analysis reveals that branch-site plasticity contributes to splicing regulation. Hum Mol Genet (2005) 1.71
DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure. Genome Res (2013) 1.44
Differential GC content between exons and introns establishes distinct strategies of splice-site recognition. Cell Rep (2012) 1.41
Intronic Alus influence alternative splicing. PLoS Genet (2008) 1.35
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The importance of being divisible by three in alternative splicing. Nucleic Acids Res (2005) 1.29
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Alu exonization events reveal features required for precise recognition of exons by the splicing machinery. PLoS Comput Biol (2009) 1.20
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The emergence of alternative 3' and 5' splice site exons from constitutive exons. PLoS Comput Biol (2007) 1.15
Multifactorial interplay controls the splicing profile of Alu-derived exons. Mol Cell Biol (2008) 1.12
Alternative splicing of Alu exons--two arms are better than one. Nucleic Acids Res (2008) 1.11
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Alternative splicing regulates biogenesis of miRNAs located across exon-intron junctions. Mol Cell (2013) 1.03
IKAP/hELP1 deficiency in the cerebrum of familial dysautonomia patients results in down regulation of genes involved in oligodendrocyte differentiation and in myelination. Hum Mol Genet (2007) 1.01
Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells. PLoS One (2010) 0.98
IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia. Hum Mol Genet (2011) 0.96
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Alternative approach to a heavy weight problem. Genome Res (2007) 0.92
Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene. BMC Mol Biol (2007) 0.91
Stress alters the subcellular distribution of hSlu7 and thus modulates alternative splicing. J Cell Sci (2005) 0.91
Alternative splicing and disease. RNA Biol (2008) 0.89
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Reversible inhibition of the second step of splicing suggests a possible role of zinc in the second step of splicing. Nucleic Acids Res (2002) 0.87
Bioactivation of carbamate-based 20(S)-camptothecin prodrugs. Bioorg Med Chem (2004) 0.86
Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing. RNA (2007) 0.82
Pre-mRNA splicing is a determinant of nucleosome organization. PLoS One (2013) 0.82
When epigenetics meets alternative splicing: the roles of DNA methylation and GC architecture. Epigenomics (2013) 0.81
Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus. Mol Biol Cell (2004) 0.80
Overlapping splicing regulatory motifs--combinatorial effects on splicing. Nucleic Acids Res (2010) 0.79
Transduplication resulted in the incorporation of two protein-coding sequences into the turmoil-1 transposable element of C. elegans. Biol Direct (2008) 0.78
Boric acid reversibly inhibits the second step of pre-mRNA splicing. FEBS Lett (2003) 0.78
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