Published in Proc Natl Acad Sci U S A on June 18, 2010
Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter. Nat Struct Mol Biol (2011) 1.51
Mammalian transcription factor A is a core component of the mitochondrial transcription machinery. Proc Natl Acad Sci U S A (2012) 1.37
Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease. Mol Cell (2012) 1.28
Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice. Am J Pathol (2011) 1.18
Transcriptional activation by mitochondrial transcription factor A involves preferential distortion of promoter DNA. Nucleic Acids Res (2011) 1.15
Mitochondrial DNA damage and its consequences for mitochondrial gene expression. Biochim Biophys Acta (2012) 1.12
LRP130 protein remodels mitochondria and stimulates fatty acid oxidation. J Biol Chem (2011) 1.03
Accessorizing the human mitochondrial transcription machinery. Trends Biochem Sci (2013) 1.03
Mitochondrial ribosomal protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription. Proc Natl Acad Sci U S A (2011) 1.02
Mitochondrial DNA transcription regulation and nucleoid organization. J Inherit Metab Dis (2011) 1.00
A novel intermediate in transcription initiation by human mitochondrial RNA polymerase. Nucleic Acids Res (2014) 0.98
Effects of early life exposure to ultraviolet C radiation on mitochondrial DNA content, transcription, ATP production, and oxygen consumption in developing Caenorhabditis elegans. BMC Pharmacol Toxicol (2013) 0.97
Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis. Nucleic Acids Res (2013) 0.96
Human Cockayne syndrome B protein reciprocally communicates with mitochondrial proteins and promotes transcriptional elongation. Nucleic Acids Res (2012) 0.94
Mechanism of transcription initiation by the yeast mitochondrial RNA polymerase. Biochim Biophys Acta (2012) 0.93
Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro. Proc Natl Acad Sci U S A (2012) 0.93
The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation. Nucleic Acids Res (2014) 0.92
The N-terminal domain of the yeast mitochondrial RNA polymerase regulates multiple steps of transcription. J Biol Chem (2011) 0.91
Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I. Nucleic Acids Res (2013) 0.90
Amino acid starvation has opposite effects on mitochondrial and cytosolic protein synthesis. PLoS One (2014) 0.90
Transcriptional requirements of the distal heavy-strand promoter of mtDNA. Proc Natl Acad Sci U S A (2012) 0.89
Opening-closing dynamics of the mitochondrial transcription pre-initiation complex. Nucleic Acids Res (2011) 0.89
Mitochondrial transcription: lessons from mouse models. Biochim Biophys Acta (2011) 0.88
Transcription factor-dependent DNA bending governs promoter recognition by the mitochondrial RNA polymerase. J Biol Chem (2011) 0.87
Matrix proteases in mitochondrial DNA function. Biochim Biophys Acta (2011) 0.87
Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation. J Clin Invest (2014) 0.86
Conservation of promoter melting mechanisms in divergent regions of the single-subunit RNA polymerases. Biochemistry (2012) 0.86
Organization of the human mitochondrial transcription initiation complex. Nucleic Acids Res (2014) 0.84
Hitting the brakes: termination of mitochondrial transcription. Biochim Biophys Acta (2011) 0.84
Identification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe. Nucleic Acids Res (2011) 0.82
New insights into plastid nucleoid structure and functionality. Planta (2012) 0.82
Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1. Nucleic Acids Res (2013) 0.82
Mitochondrial genome-maintaining activity of mouse mitochondrial transcription factor A and its transcript isoform in Saccharomyces cerevisiae. Gene (2011) 0.76
Human mitochondrial transcription factors TFAM and TFB2M work synergistically in promoter melting during transcription initiation. Nucleic Acids Res (2016) 0.75
Initiation of mtDNA transcription is followed by pausing, and diverge across human cell types and during evolution. Genome Res (2017) 0.75
Expression and Purification of Mitochondrial RNA Polymerase and Transcription Factor A from Drosophila melanogaster. Methods Mol Biol (2016) 0.75
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet (2005) 16.79
Mitochondrial DNA maintenance in vertebrates. Annu Rev Biochem (1997) 4.96
Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. Nat Genet (2002) 4.48
Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. Science (1991) 4.26
Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7. Cell (1987) 3.83
DNA replication and transcription in mammalian mitochondria. Annu Rev Biochem (2007) 3.74
Initiation and beyond: multiple functions of the human mitochondrial transcription machinery. Mol Cell (2006) 3.16
Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome. Cell Metab (2009) 3.06
Priming of human mitochondrial DNA replication occurs at the light-strand promoter. Proc Natl Acad Sci U S A (1985) 3.05
Purification and characterization of human mitochondrial transcription factor 1. Mol Cell Biol (1988) 2.78
MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell (2007) 2.76
The layered structure of human mitochondrial DNA nucleoids. J Biol Chem (2007) 2.74
The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes. Nat Genet (2008) 2.58
Identification of initiation sites for heavy-strand and light-strand transcription in human mitochondrial DNA. Proc Natl Acad Sci U S A (1982) 2.55
Promoter selection in human mitochondria involves binding of a transcription factor to orientation-independent upstream regulatory elements. Cell (1987) 2.44
The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures. Mol Biol Cell (2007) 2.42
DNA binding properties of an HMG1-related protein from yeast mitochondria. J Biol Chem (1992) 2.23
The functional organization of mitochondrial genomes in human cells. BMC Biol (2004) 2.20
Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator. J Mol Biol (1995) 2.17
Human mitochondrial DNA nucleoids are linked to protein folding machinery and metabolic enzymes at the mitochondrial inner membrane. J Biol Chem (2006) 2.16
Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database. Hum Mol Genet (1997) 2.15
Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle. Cell (1977) 2.09
Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis. Cell (2005) 2.01
In organello formaldehyde crosslinking of proteins to mtDNA: identification of bifunctional proteins. Proc Natl Acad Sci U S A (2000) 1.94
Evidence for a two membrane-spanning autonomous mitochondrial DNA replisome. J Cell Biol (2003) 1.92
Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop. Nat Genet (2002) 1.89
The yeast mitochondrial RNA polymerase specificity factor, MTF1, is similar to bacterial sigma factors. J Biol Chem (1991) 1.88
A transcription factor required for promoter recognition by human mitochondrial RNA polymerase. Accurate initiation at the heavy- and light-strand promoters dissected and reconstituted in vitro. J Biol Chem (1985) 1.86
A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine. Mol Cell Biol (2002) 1.85
Initiation of mitochondrial DNA replication by transcription and R-loop processing. J Biol Chem (1998) 1.83
The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells. EMBO J (2004) 1.81
Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity. Mol Cell Biol (2003) 1.80
Expression and maintenance of mitochondrial DNA: new insights into human disease pathology. Am J Pathol (2008) 1.78
TFB2 is a transient component of the catalytic site of the human mitochondrial RNA polymerase. Cell (2009) 1.75
Mitochondrial transcription initiation. Variation and conservation. J Biol Chem (1993) 1.74
Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro. J Biol Chem (2010) 1.67
Organization of multiple nucleoids and DNA molecules in mitochondria of a human cell. Exp Cell Res (1991) 1.61
Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein. EMBO Rep (2002) 1.61
Relative abundance of the human mitochondrial transcription system and distinct roles for h-mtTFB1 and h-mtTFB2 in mitochondrial biogenesis and gene expression. Nucleic Acids Res (2007) 1.60
Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression. J Biol Chem (2007) 1.54
Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells. Nucleic Acids Res (2004) 1.53
The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization. J Cell Biol (2007) 1.53
Functional organization of mammalian mitochondrial DNA in nucleoids: history, recent developments, and future challenges. IUBMB Life (2010) 1.52
Human mitochondrial transcription factor A and promoter spacing integrity are required for transcription initiation. Biochim Biophys Acta (1995) 1.43
Conserved sequence box II directs transcription termination and primer formation in mitochondria. J Biol Chem (2006) 1.40
Assignment of a yeast protein necessary for mitochondrial transcription initiation. Nucleic Acids Res (1992) 1.40
The MTERF family proteins: mitochondrial transcription regulators and beyond. Biochim Biophys Acta (2009) 1.38
Drosophila mitochondrial transcription factor B1 modulates mitochondrial translation but not transcription or DNA copy number in Schneider cells. J Biol Chem (2005) 1.37
Mitochondrial dysfunction due to oxidative mitochondrial DNA damage is reduced through cooperative actions of diverse proteins. Mol Cell Biol (2002) 1.35
Mitochondrial nucleoids undergo remodeling in response to metabolic cues. J Cell Sci (2008) 1.35
Drosophila mitochondrial transcription factor B2 regulates mitochondrial DNA copy number and transcription in schneider cells. J Biol Chem (2004) 1.34
Retracted mTERF2 regulates oxidative phosphorylation by modulating mtDNA transcription. Cell Metab (2009) 1.31
Evidence for an early gene duplication event in the evolution of the mitochondrial transcription factor B family and maintenance of rRNA methyltransferase activity in human mtTFB1 and mtTFB2. J Mol Evol (2006) 1.23
Identification of multiple rate-limiting steps during the human mitochondrial transcription cycle in vitro. J Biol Chem (2010) 1.09
Mitochondrial transcription: is a pattern emerging? Mol Microbiol (1993) 1.08
Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness. Hum Mol Genet (2009) 1.07
Arabidopsis phage-type RNA polymerases: accurate in vitro transcription of organellar genes. Plant Cell (2007) 1.01
Homologs of mitochondrial transcription factor B, sparsely distributed within the eukaryotic radiation, are likely derived from the dimethyladenosine methyltransferase of the mitochondrial endosymbiont. Mol Biol Evol (2006) 0.98
Regulation of mitochondrial transcription by mitochondrial transcription factor A. Mol Cell Biochem (1997) 0.97
DNA conformation-dependent activities of human mitochondrial RNA polymerase. Genes Cells (2009) 0.85
DNA binding properties of recombinant human mitochondrial transcription factor 1. Cell Mol Biol (Noisy-le-grand) (1994) 0.82
Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature (2005) 6.78
Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression. Cell Metab (2007) 4.59
Viral reorganization of the secretory pathway generates distinct organelles for RNA replication. Cell (2010) 4.47
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature (2011) 4.16
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc Natl Acad Sci U S A (2009) 3.84
Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO. Science (2013) 3.45
Mitochondria in innate immune responses. Nat Rev Immunol (2011) 3.31
Initiation and beyond: multiple functions of the human mitochondrial transcription machinery. Mol Cell (2006) 3.16
Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling. Cell Metab (2011) 3.13
Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance. Cell Metab (2010) 3.07
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell (2013) 2.94
Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein. J Biol Chem (2005) 2.61
Replicative and chronological aging in Saccharomyces cerevisiae. Cell Metab (2012) 2.56
5'-triphosphate-dependent activation of PKR by RNAs with short stem-loops. Science (2007) 2.48
Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase. J Biol Chem (2005) 2.40
A 5' RNA element promotes dengue virus RNA synthesis on a circular genome. Genes Dev (2006) 2.27
Nucleic acid polymerases use a general acid for nucleotidyl transfer. Nat Struct Mol Biol (2009) 2.13
Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+. Biochemistry (2004) 2.10
Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis. J Clin Invest (2007) 2.03
Epigenetic silencing mediates mitochondria stress-induced longevity. Cell Metab (2013) 2.03
Mechanisms of action of ribavirin against distinct viruses. Rev Med Virol (2005) 2.00
Molecular and biological characterization of deformed wing virus of honeybees (Apis mellifera L.). J Virol (2006) 1.93
Structure-function relationships among RNA-dependent RNA polymerases. Curr Top Microbiol Immunol (2008) 1.90
Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop. Nat Genet (2002) 1.89
A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine. Mol Cell Biol (2002) 1.85
Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density. Aging (Albany NY) (2009) 1.82
Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity. Mol Cell Biol (2003) 1.80
Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection. Biochemistry (2004) 1.76
Motif D of viral RNA-dependent RNA polymerases determines efficiency and fidelity of nucleotide addition. Structure (2012) 1.71
Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis. Biochim Biophys Acta (2009) 1.67
Isolation of enzymatically active replication complexes from feline calicivirus-infected cells. J Virol (2002) 1.67
Modulation of mitochondrial transcription in response to mtDNA depletion and repletion in HeLa cells. Nucleic Acids Res (2002) 1.64
Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation. J Biol Chem (2002) 1.61
Relative abundance of the human mitochondrial transcription system and distinct roles for h-mtTFB1 and h-mtTFB2 in mitochondrial biogenesis and gene expression. Nucleic Acids Res (2007) 1.60
Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing. Proc Natl Acad Sci U S A (2011) 1.60
Hepatitis C virus non-structural protein 3 (HCV NS3): a multifunctional antiviral target. J Biol Chem (2010) 1.58
Ancient mtDNA genetic variants modulate mtDNA transcription and replication. PLoS Genet (2009) 1.58
Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence. J Cell Biol (2008) 1.56
Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness. Cell (2012) 1.56
Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases. Proc Natl Acad Sci U S A (2007) 1.55
Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression. J Biol Chem (2007) 1.54
Revisiting the TCA cycle: signaling to tumor formation. Trends Mol Med (2011) 1.51
Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+. Biochemistry (2004) 1.50
The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage. J Mol Biol (2002) 1.48
Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective. Virus Res (2005) 1.48
Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase. J Virol (2007) 1.48
Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span. Mol Cell Biol (2006) 1.47
Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli. Protein Expr Purif (2004) 1.45
The conserved Mec1/Rad53 nuclear checkpoint pathway regulates mitochondrial DNA copy number in Saccharomyces cerevisiae. Mol Biol Cell (2005) 1.45
HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors. J Hepatol (2010) 1.43
Mitochondrial respiratory thresholds regulate yeast chronological life span and its extension by caloric restriction. Cell Metab (2012) 1.41
Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis. J Gen Virol (2006) 1.39
Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis. J Biol Chem (2003) 1.38
The genomic landscape of cohesin-associated chromatin interactions. Genome Res (2013) 1.36
Mitochondrial dysfunction due to oxidative mitochondrial DNA damage is reduced through cooperative actions of diverse proteins. Mol Cell Biol (2002) 1.35
Inhibition of dengue virus replication by mycophenolic acid and ribavirin. J Gen Virol (2006) 1.30
Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro. J Biol Chem (2005) 1.30
Quasispecies, error catastrophe, and the antiviral activity of ribavirin. Virology (2002) 1.28
Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus. J Biol Chem (2005) 1.28
A compendium of human mitochondrial gene expression machinery with links to disease. Environ Mol Mutagen (2010) 1.26
Evidence for an early gene duplication event in the evolution of the mitochondrial transcription factor B family and maintenance of rRNA methyltransferase activity in human mtTFB1 and mtTFB2. J Mol Evol (2006) 1.23
Structure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocket. J Biol Chem (2007) 1.23
Pleiotropic mechanisms of ribavirin antiviral activities. Prog Drug Res (2002) 1.22
Molecular dynamics simulations of viral RNA polymerases link conserved and correlated motions of functional elements to fidelity. J Mol Biol (2011) 1.22
Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics (2002) 1.22
Convergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation. Mitochondrion (2007) 1.21
Oxidative DNA damage causes mitochondrial genomic instability in Saccharomyces cerevisiae. Mol Cell Biol (2005) 1.21
Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice. Am J Pathol (2011) 1.18
A novel mitochondrial protein, Tar1p, is encoded on the antisense strand of the nuclear 25S rDNA. Genes Dev (2002) 1.16
Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex. J Biol Chem (2007) 1.16
Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue. J Virol (2007) 1.16
Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins. J Virol (2010) 1.15
Transcriptional activation by mitochondrial transcription factor A involves preferential distortion of promoter DNA. Nucleic Acids Res (2011) 1.15
The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent. Nucleic Acids Res (2009) 1.14
Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides. PLoS Pathog (2012) 1.11
Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole. Biochemistry (2002) 1.11
Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors. Crit Care Med (2009) 1.10
Identification of multiple rate-limiting steps during the human mitochondrial transcription cycle in vitro. J Biol Chem (2010) 1.09
Differential involvement of the related DNA helicases Pif1p and Rrm3p in mtDNA point mutagenesis and stability. Gene (2005) 1.08
An on-chip, multichannel droplet sorter using standing surface acoustic waves. Anal Chem (2013) 1.08
Cell cycle- and ribonucleotide reductase-driven changes in mtDNA copy number influence mtDNA Inheritance without compromising mitochondrial gene expression. Cell Cycle (2007) 1.07
Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues. Antimicrob Agents Chemother (2008) 1.07
Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness. Hum Mol Genet (2009) 1.07
Challenges for the development of ribonucleoside analogues as inducers of error catastrophe. Antivir Chem Chemother (2004) 1.07
A Polymerase mechanism-based strategy for viral attenuation and vaccine development. J Biol Chem (2012) 1.06
Rethinking the mitochondrial theory of aging: the role of mitochondrial gene expression in lifespan determination. Cell Cycle (2007) 1.05
Norovirus proteinase-polymerase and polymerase are both active forms of RNA-dependent RNA polymerase. J Virol (2005) 1.05
NS3 helicase from the hepatitis C virus can function as a monomer or oligomer depending on enzyme and substrate concentrations. J Biol Chem (2008) 1.04
LRP130 protein remodels mitochondria and stimulates fatty acid oxidation. J Biol Chem (2011) 1.03
Excess ribonucleotide reductase R2 subunits coordinate the S phase checkpoint to facilitate DNA damage repair and recovery from replication stress. Biochem Pharmacol (2006) 1.03
Accessorizing the human mitochondrial transcription machinery. Trends Biochem Sci (2013) 1.03
Mitochondrial ribosomal protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription. Proc Natl Acad Sci U S A (2011) 1.02
Lethal mutagens: broad-spectrum antivirals with limited potential for development of resistance? Drug Resist Updat (2004) 1.02
Correlation between NS5A dimerization and hepatitis C virus replication. J Biol Chem (2012) 1.01