Published in PLoS Genet on August 19, 2010
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Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63. Oncotarget (2012) 1.00
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Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition. Dev Cell (2013) 0.95
p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model. PLoS One (2013) 0.94
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An etiologic regulatory mutation in IRF6 with loss- and gain-of-function effects. Hum Mol Genet (2014) 0.89
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Deletions of exons with regulatory activity at the DYNC1I1 locus are associated with split-hand/split-foot malformation: array CGH screening of 134 unrelated families. Orphanet J Rare Dis (2014) 0.89
p63 maintains keratinocyte proliferative capacity through regulation of Skp2-p130 levels. J Cell Sci (2011) 0.87
APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations. Proc Natl Acad Sci U S A (2013) 0.86
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DLX5, FGF8 and the Pin1 isomerase control ΔNp63α protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations. Hum Mol Genet (2014) 0.86
Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress. Nucleic Acids Res (2014) 0.85
Split-hand/foot malformation - molecular cause and implications in genetic counseling. J Appl Genet (2013) 0.84
Analysis of large phenotypic variability of EEC and SHFM4 syndromes caused by K193E mutation of the TP63 gene. PLoS One (2012) 0.83
A LINE-1 insertion in DLX6 is responsible for cleft palate and mandibular abnormalities in a canine model of Pierre Robin sequence. PLoS Genet (2014) 0.83
p63 supports aerobic respiration through hexokinase II. Proc Natl Acad Sci U S A (2015) 0.81
ΔNp63α Promotes Breast Cancer Cell Motility through the Selective Activation of Components of the Epithelial-to-Mesenchymal Transition Program. Cancer Res (2015) 0.80
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Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytes. BMC Genomics (2014) 0.79
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A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms. Nucleic Acids Res (2015) 0.78
Sp6 and Sp8 transcription factors control AER formation and dorsal-ventral patterning in limb development. PLoS Genet (2014) 0.77
Split hand/foot malformation genetics supports the chromosome 7 copy segregation mechanism for human limb development. Philos Trans R Soc Lond B Biol Sci (2016) 0.77
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The dlx5a/dlx6a genes play essential roles in the early development of zebrafish median fin and pectoral structures. PLoS One (2014) 0.77
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A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues. BMC Genomics (2015) 0.77
p53 and ΔNp63α Coregulate the Transcriptional and Cellular Response to TGFβ and BMP Signals. Mol Cancer Res (2015) 0.77
The downregulation of ΔNp63 in p53-deficient mouse epidermal tumors favors metastatic behavior. Oncotarget (2015) 0.77
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p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis. Exp Dermatol (2015) 0.76
ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells. Cell Cycle (2013) 0.76
The wind rose of human keratinocyte cell fate. Cell Mol Life Sci (2014) 0.76
p63 transcription factor regulates nuclear shape and expression of nuclear envelope-associated genes in epidermal keratinocytes. J Invest Dermatol (2017) 0.75
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PFKFB3, a direct target of p63, is required for proliferation and inhibits differentiation in epidermal keratinocytes. J Invest Dermatol (2017) 0.75
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