A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity.

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Published in Leukemia on November 12, 2010

Authors

S-H Chen1, W Yang, Y Fan, G Stocco, K R Crews, J J Yang, S W Paugh, C-H Pui, W E Evans, M V Relling

Author Affiliations

1: Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN 38105, USA.

Associated clinical trials:

Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia | NCT00137111

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