Lineage tracing.

In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding. Cell Metab (2012) 3.90

Clonal dynamics of native haematopoiesis. Nature (2014) 3.15

Alveolar progenitor and stem cells in lung development, renewal and cancer. Nature (2014) 2.71

In situ identification of bipotent stem cells in the mammary gland. Nature (2014) 2.71

Pluripotent stem cells in regenerative medicine: challenges and recent progress. Nat Rev Genet (2014) 2.12

Long-lived intestinal tuft cells serve as colon cancer-initiating cells. J Clin Invest (2014) 1.90

Regenerating new heart with stem cells. J Clin Invest (2013) 1.83

Unravelling stem cell dynamics by lineage tracing. Nat Rev Mol Cell Biol (2013) 1.53

Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development (2013) 1.43

Cell lineage analysis in human brain using endogenous retroelements. Neuron (2015) 1.39

A matter of life and death: self-renewal in stem cells. EMBO Rep (2012) 1.30

Human pluripotent stem cells: an emerging model in developmental biology. Development (2013) 1.22

Moderate and high amounts of tamoxifen in αMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death. Dis Model Mech (2013) 1.16

Tracing epithelial stem cells during development, homeostasis, and repair. J Cell Biol (2012) 1.16

Pathology of rodent models of intestinal cancer: progress report and recommendations. Gastroenterology (2013) 1.12

EMT and interstitial lung disease: a mysterious relationship. Curr Opin Pulm Med (2012) 1.12

Optimized tools for multicolor stochastic labeling reveal diverse stereotyped cell arrangements in the fly visual system. Proc Natl Acad Sci U S A (2015) 1.09

Heterogeneity and plasticity of epidermal stem cells. Development (2014) 1.08

Pref-1, a gatekeeper of adipogenesis. Front Endocrinol (Lausanne) (2013) 1.06

Whole-organism lineage tracing by combinatorial and cumulative genome editing. Science (2016) 1.06

Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Development (2013) 1.02

Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation. J Invest Dermatol (2015) 1.01

Differentiation of progenitors in the liver: a matter of local choice. J Clin Invest (2013) 1.00

Tissue stem cells: new tools and functional diversity. Cell Stem Cell (2012) 1.00

Tracking cells in their native habitat: lineage tracing in epithelial neoplasia. Nat Rev Cancer (2013) 1.00

Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction. EMBO Mol Med (2014) 1.00

New insights into lineage restriction of mammary gland epithelium using parity-identified mammary epithelial cells. Breast Cancer Res (2014) 0.96

Evidence for and against epithelial-to-mesenchymal transition in the liver. Am J Physiol Gastrointest Liver Physiol (2013) 0.96

The use of lineage tracing to study kidney injury and regeneration. Nat Rev Nephrol (2015) 0.95

Markers of epidermal stem cell subpopulations in adult mammalian skin. Cold Spring Harb Perspect Med (2014) 0.95

Spatiotemporal coordination of stem cell commitment during epidermal homeostasis. Science (2016) 0.95

Ciliated cells of pseudostratified airway epithelium do not become mucous cells after ovalbumin challenge. Am J Respir Cell Mol Biol (2012) 0.95

Quantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cells. Genes Dev (2016) 0.95

Regeneration and repair of the exocrine pancreas. Annu Rev Physiol (2014) 0.94

Cardiac outflow tract anomalies. Wiley Interdiscip Rev Dev Biol (2013) 0.92

Non-parallel recombination limits Cre-LoxP-based reporters as precise indicators of conditional genetic manipulation. Genesis (2013) 0.91

TIE-DYE: a combinatorial marking system to visualize and genetically manipulate clones during development in Drosophila melanogaster. Development (2013) 0.91

Lineage tracing of mammary epithelial cells using cell-type-specific cre-expressing adenoviruses. Stem Cell Reports (2014) 0.89

Precision cancer mouse models through genome editing with CRISPR-Cas9. Genome Med (2015) 0.89

Melanocytes, melanocyte stem cells, and melanoma stem cells. Clin Dermatol (2013) 0.87

Emerging Complexities in Adipocyte Origins and Identity. Trends Cell Biol (2016) 0.87

Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase. Mol Metab (2015) 0.86

Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence". Cancer Metastasis Rev (2013) 0.86

Lineage analysis of epidermal stem cells. Cold Spring Harb Perspect Med (2014) 0.86

Tools for Single-Cell Kinetic Analysis of Virus-Host Interactions. PLoS One (2016) 0.85

The niche in single-cell technologies. Immunol Cell Biol (2015) 0.85

Pathogenesis of pancreatic cancer: lessons from animal models. Toxicol Pathol (2013) 0.84

Seeking the source of adipocytes in adult white adipose tissues. Adipocyte (2012) 0.84

Hypertrophic chondrocytes in the rabbit growth plate can proliferate and differentiate into osteogenic cells when capillary invasion is interposed by a membrane filter. PLoS One (2014) 0.84

Exact, time-independent estimation of clone size distributions in normal and mutated cells. J R Soc Interface (2014) 0.84

Rescuing failed oral implants via Wnt activation. J Clin Periodontol (2016) 0.83

A multicolor podocyte reporter highlights heterogeneous podocyte changes in focal segmental glomerulosclerosis. Kidney Int (2013) 0.83

Cell lineage tracing in the developing enteric nervous system: superstars revealed by experiment and simulation. J R Soc Interface (2014) 0.83

Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development. PLoS One (2013) 0.82

Structure and function of LGR5: an enigmatic G-protein coupled receptor marking stem cells. Protein Sci (2014) 0.82

Deconstructing signaling in three dimensions. Biochemistry (2014) 0.81

Genetic lineage tracing discloses arteriogenesis as the main mechanism for collateral growth in the mouse heart. Cardiovasc Res (2016) 0.81

Fate mapping of dendritic cells. Front Immunol (2015) 0.81

BLIMP1 is required for postnatal epidermal homeostasis but does not define a sebaceous gland progenitor under steady-state conditions. Stem Cell Reports (2014) 0.81

Preexisting endothelial cells mediate cardiac neovascularization after injury. J Clin Invest (2017) 0.81

Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity. Cell Rep (2016) 0.80

Highly efficient baculovirus-mediated multigene delivery in primary cells. Nat Commun (2016) 0.78

Dynamic heterogeneity as a strategy of stem cell self-renewal. Proc Natl Acad Sci U S A (2016) 0.78

Spatiotemporal analyses of neural lineages after embryonic and postnatal progenitor targeting combining different reporters. Front Neurosci (2015) 0.78

Cardiomyocyte proliferation vs progenitor cells in myocardial regeneration: The debate continues. Glob Cardiol Sci Pract (2013) 0.78

Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis. Lab Invest (2015) 0.78

Rapidly evolving homing CRISPR barcodes. Nat Methods (2016) 0.78

The dynamics of murine mammary stem/progenitor cells. Front Biol (Beijing) (2014) 0.78

Optimizing mouse models for precision cancer prevention. Nat Rev Cancer (2016) 0.77

Seeing through Musculoskeletal Tissues: Improving In Situ Imaging of Bone and the Lacunar Canalicular System through Optical Clearing. PLoS One (2016) 0.77

A dual-color genetically engineered mouse model for multispectral imaging of the pancreatic microenvironment. Pancreas (2013) 0.77

Germ stem cells are active in postnatal mouse ovary under physiological conditions. Mol Hum Reprod (2016) 0.77

Cells of origin of pancreatic neoplasms. Surg Today (2017) 0.77

Deep insights: intravital imaging with two-photon microscopy. Pflugers Arch (2016) 0.76

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice. J Vis Exp (2015) 0.76

Lessons from mouse chimaera experiments with a reiterated transgene marker: revised marker criteria and a review of chimaera markers. Transgenic Res (2015) 0.76

Ovine Hair Follicle Stem Cells Derived from Single Vibrissae Reconstitute Haired Skin. Int J Mol Sci (2015) 0.76

Highly selective in vivo labeling of subcutaneous white adipocyte precursors with Prx1-Cre. Stem Cell Reports (2015) 0.76

Transgenic Strategies to Study Podocyte Loss and Regeneration. Stem Cells Int (2015) 0.76

Clinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: a prospective case series. Stem Cell Res Ther (2015) 0.76

Defining a stem cell hierarchy in the intestine: markers, caveats and controversies. J Physiol (2016) 0.76

Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functions. Oncotarget (2016) 0.75

Live Imaging of Adult Neural Stem Cells in Rodents. Front Neurosci (2016) 0.75

Site-specific recombinatorics: in situ cellular barcoding with the Cre Lox system. BMC Syst Biol (2016) 0.75

Tell me about your stemness. I'll give your cancer risk! Cell Death Differ (2016) 0.75

Invariant asymmetry renews the lymphatic vasculature during homeostasis. J Transl Med (2016) 0.75

Cellular mechanisms of alveolar pathology in childhood interstitial lung diseases: current insights from mouse genetics. Curr Opin Pediatr (2015) 0.75

Involvement of activation-induced cytidine deaminase in skin cancer development. J Clin Invest (2016) 0.75

Coalescent models for developmental biology and the spatio-temporal dynamics of growing tissues. J R Soc Interface (2016) 0.75

Stem cell dynamics and pretumor progression in the intestinal tract. J Gastroenterol (2016) 0.75

Co-localization of Cell Lineage Markers and the Tomato Signal. J Vis Exp (2016) 0.75

MiR-210 promotes sensory hair cell formation in the organ of corti. BMC Genomics (2016) 0.75

Multiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosome. FEBS Open Bio (2017) 0.75

GLI1(+) progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue. Mol Cell Endocrinol (2016) 0.75

Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury. Sci Rep (2017) 0.75

A generic, cost-effective, and scalable cell lineage analysis platform. Genome Res (2016) 0.75

Of fish and men: clonal lineage analysis identifies divergence in myocardial development. Circ Res (2013) 0.75

Lineage mapper: A versatile cell and particle tracker. Sci Rep (2016) 0.75

Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment. Stem Cells Int (2017) 0.75

Everything has its time: Id2 clocks embryonic specification of Lgr5(+) gut stem cells. EMBO J (2017) 0.75

Autophagy mediates the mitotic senescence transition. Genes Dev (2009) 6.80

Extracellular-matrix tethering regulates stem-cell fate. Nat Mater (2012) 3.94

Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis. Development (2003) 3.84

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell (2013) 3.47

Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell (2009) 3.44

Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nat Cell Biol (2010) 3.33

Stem cell depletion through epidermal deletion of Rac1. Science (2005) 3.26

Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development (2004) 3.24

Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci U S A (2006) 2.91

Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development (2009) 2.82

Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development (2002) 2.79

Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell (2005) 2.71

Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer (2003) 2.69

Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol (2012) 2.51

Stem cells are dispensable for lung homeostasis but restore airways after injury. Proc Natl Acad Sci U S A (2009) 2.28

Epithelial stem cells, wound healing and cancer. Nat Rev Cancer (2012) 2.23

Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment. Development (2003) 2.23

Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development (2006) 2.06

The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development (2006) 2.04

A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development (2002) 2.04

Sic transit gloria: farewell to the epidermal transit amplifying cell? Cell Stem Cell (2007) 1.91

The basement membrane of hair follicle stem cells is a muscle cell niche. Cell (2011) 1.88

Defining dermal adipose tissue. Exp Dermatol (2014) 1.84

Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3. Nat Cell Biol (2008) 1.79

New roles for integrins in squamous-cell carcinoma. Nat Rev Cancer (2006) 1.75

Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis. Nat Protoc (2010) 1.72

Hair follicle dermal papilla cells at a glance. J Cell Sci (2011) 1.72

The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors. Curr Biol (2006) 1.71

Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. J Cell Biol (2006) 1.65

Designer skin: lineage commitment in postnatal epidermis. Trends Cell Biol (2002) 1.59

Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. Curr Biol (2003) 1.54

The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS One (2008) 1.53

Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs. Nat Genet (2005) 1.51

The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate. PLoS Genet (2011) 1.48

Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. PLoS One (2007) 1.45

Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin. Development (2011) 1.43

Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis. Development (2003) 1.42

Human sebaceous tumors harbor inactivating mutations in LEF1. Nat Med (2006) 1.40

Suprabasal alpha6beta4 integrin expression in epidermis results in enhanced tumourigenesis and disruption of TGFbeta signalling. J Cell Sci (2003) 1.37

Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways. J Cell Sci (2003) 1.37

Epidermal stem cells are retained in vivo throughout skin aging. Aging Cell (2008) 1.31

Clonal growth of dermal papilla cells in hydrogels reveals intrinsic differences between Sox2-positive and -negative cells in vitro and in vivo. J Invest Dermatol (2011) 1.30

Switch from alphavbeta5 to alphavbeta6 integrin expression protects squamous cell carcinomas from anoikis. J Cell Biol (2004) 1.30

Diverse epigenetic strategies interact to control epidermal differentiation. Nat Cell Biol (2012) 1.29

Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions. J Invest Dermatol (2004) 1.27

Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt. J Cell Sci (2004) 1.22

Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate. Proc Natl Acad Sci U S A (2010) 1.22

Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin. Stem Cells (2008) 1.22

Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier. J Cell Biol (2007) 1.22

What is the point of large-scale collections of human induced pluripotent stem cells? Nat Biotechnol (2013) 1.20

Epidermal label-retaining cells: background and recent applications. J Investig Dermatol Symp Proc (2004) 1.20

The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1. Stem Cell Reports (2013) 1.20

Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. Dev Biol (2008) 1.19

A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control. J Cell Biol (2003) 1.18

A year in the life of eLife. Elife (2013) 1.14

Role of LIM kinases in normal and psoriatic human epidermis. Mol Biol Cell (2006) 1.14

Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. J Invest Dermatol (2007) 1.11

Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type. Cancer Res (2007) 1.09

Syntenin mediates Delta1-induced cohesiveness of epidermal stem cells in culture. J Cell Sci (2007) 1.08

Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation. Dev Biol (2010) 1.06

Human skin aging is associated with reduced expression of the stem cell markers beta1 integrin and MCSP. J Invest Dermatol (2009) 1.05

Regulation of interleukin-1alpha expression by integrins and epidermal growth factor receptor in keratinocytes from a mouse model of inflammatory skin disease. J Biol Chem (2003) 1.05

Exploiting the superior protein resistance of polymer brushes to control single cell adhesion and polarisation at the micron scale. Biomaterials (2010) 1.04

Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells. Development (2013) 1.04

Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol (2013) 1.03

Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation. EMBO Mol Med (2010) 1.02

Kazrin, a novel periplakin-interacting protein associated with desmosomes and the keratinocyte plasma membrane. J Cell Biol (2004) 1.02

A stem cell gene expression profile of human squamous cell carcinomas. Cancer Lett (2008) 1.01

Necl2 regulates epidermal adhesion and wound repair. Development (2009) 1.01

Interaction of periplakin and envoplakin with intermediate filaments. J Cell Sci (2002) 1.01

Different consequences of beta1 integrin deletion in neonatal and adult mouse epidermis reveal a context-dependent role of integrins in regulating proliferation, differentiation, and intercellular communication. J Invest Dermatol (2005) 1.01

Expression of Notch pathway genes in mammalian epidermis and modulation by beta-catenin. Dev Dyn (2007) 0.99

FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis. Cancer Res (2012) 0.97

c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis. Cell Rep (2013) 0.97

An activating beta1 integrin mutation increases the conversion of benign to malignant skin tumors. Cancer Res (2009) 0.96

Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1. Development (2010) 0.93

Kazrin regulates keratinocyte cytoskeletal networks, intercellular junctions and differentiation. J Cell Sci (2008) 0.93

β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition. J Pathol (2012) 0.92

LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development. J Pathol (2013) 0.92

Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors. Proc Natl Acad Sci U S A (2014) 0.91

KazrinE is a desmosome-associated liprin that colocalises with acetylated microtubules. J Cell Sci (2009) 0.91

Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer. Cancer Lett (2009) 0.91

Suprabasal alpha 5 beta1 integrin expression stimulates formation of epidermal squamous cell carcinomas without disrupting TGFbeta signaling or inducing spindle cell tumors. Mol Carcinog (2005) 0.89

PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of epidermal keratinocytes to terminal differentiation. Cell Res (2009) 0.88

Advancing research. Elife (2014) 0.88

HAN11 binds mDia1 and controls GLI1 transcriptional activity. J Dermatol Sci (2006) 0.88

Efficient differentiation of embryonic stem cells into mesodermal precursors by BMP, retinoic acid and Notch signalling. PLoS One (2012) 0.88

Non-profit publishing: open access and the end of copyright transfer. J Cell Sci (2004) 0.88

Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation. PLoS One (2011) 0.88

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells. Proc Natl Acad Sci U S A (2013) 0.87

KazrinA is required for axial elongation and epidermal integrity in Xenopus tropicalis. Dev Dyn (2008) 0.87

Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity. J Cell Sci (2010) 0.86

Identification of novel keratinocyte differentiation modulating compounds by high-throughput screening. J Biomol Screen (2006) 0.86

Polyclonal origin and hair induction ability of dermal papillae in neonatal and adult mouse back skin. Dev Biol (2012) 0.84

High-throughput stem-cell niches. Nat Methods (2011) 0.84

Epidermal Cadm1 expression promotes autoimmune alopecia via enhanced T cell adhesion and cytotoxicity. J Immunol (2011) 0.83

The vitamin D receptor is required for mouse hair cycle progression but not for maintenance of the epidermal stem cell compartment. J Invest Dermatol (2008) 0.83

Sequence variation in the I-like domain of the beta1 integrin subunit in human oral squamous cell carcinomas. Cancer Lett (2004) 0.82

Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis. Biomaterials (2012) 0.82

Epidermal deletion of Rac1 causes stem cell depletion, irrespective of whether deletion occurs during embryogenesis or adulthood. J Invest Dermatol (2007) 0.81