Published in Curr Opin Crit Care on June 01, 2012
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Serum lactate as a predictor of mortality in patients with infection. Intensive Care Med (2007) 1.88
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Prolonged lactate clearance is associated with increased mortality in the surgical intensive care unit. Am J Surg (2001) 1.45
Serial lactate determinations for prediction of outcome after cardiac arrest. Medicine (Baltimore) (2004) 1.42
Opening the microcirculation: can vasodilators be useful in sepsis? Intensive Care Med (2002) 1.35
Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock? J Crit Care (2010) 1.34
Point: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? Yes. Chest (2011) 1.33
Lactic acidosis: from sour milk to septic shock. J Intensive Care Med (2005) 1.31
Lactate: biomarker and potential therapeutic target. Crit Care Clin (2011) 1.29
Systematic review of randomized clinical trials on the use of hydroxyethyl starch for fluid management in sepsis. BMC Emerg Med (2008) 1.25
A systematic review of experimental treatments for mitochondrial dysfunction in sepsis and multiple organ dysfunction syndrome. Free Radic Biol Med (2009) 1.19
Red blood cell transfusion does not increase oxygen consumption in critically ill septic patients. Crit Care (2001) 1.19
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Lactic acidosis not hyperlactatemia as a predictor of in hospital mortality in septic emergency patients. Emerg Med J (2008) 1.18
Dose-dependent benefit of nitroglycerin on microcirculation of patients with severe heart failure. Intensive Care Med (2009) 0.96
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The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Intensive Care Med (2010) 4.64
Impact of delayed transfer of critically ill patients from the emergency department to the intensive care unit. Crit Care Med (2007) 4.54
Inhaled nitric oxide does not reduce mortality in patients with acute respiratory distress syndrome regardless of severity: systematic review and meta-analysis. Crit Care Med (2014) 4.11
Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study. Lancet Infect Dis (2012) 4.07
Lactate measurements in sepsis-induced tissue hypoperfusion: results from the Surviving Sepsis Campaign database. Crit Care Med (2015) 3.55
Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival. Ann Emerg Med (2006) 3.36
The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*. Crit Care Med (2014) 3.17
Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial. JAMA (2004) 3.07
Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study. Crit Care Med (2015) 2.81
Critical care medicine training and certification for emergency physicians. Ann Emerg Med (2005) 2.67
Relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest. Circulation (2011) 2.65
Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis. Shock (2009) 2.59
Point: Are the best patient outcomes achieved when ICU bundles are rigorously adhered to? Yes. Chest (2013) 2.59
An international survey: Public awareness and perception of sepsis. Crit Care Med (2009) 2.40
Activated protein C and septic shock: a propensity-matched cohort study*. Crit Care Med (2012) 2.39
Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study. J Infect Dis (2004) 2.17
Critical care medicine training and certification for emergency physicians. Crit Care Med (2005) 2.12
Transfusion of packed red blood cells is not associated with improved central venous oxygen saturation or organ function in patients with septic shock. J Emerg Med (2012) 2.02
Sepsis change bundles: converting guidelines into meaningful change in behavior and clinical outcome. Crit Care Med (2004) 1.96
Serum lactate as a predictor of mortality in patients with infection. Intensive Care Med (2007) 1.88
Interaction between fluids and vasoactive agents on mortality in septic shock: a multicenter, observational study. Crit Care Med (2014) 1.72
A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin in patients with severe sepsis. Crit Care Med (2013) 1.58
Use of a standardized order set for achieving target temperature in the implementation of therapeutic hypothermia after cardiac arrest: a feasibility study. Acad Emerg Med (2008) 1.46
Sepsis severity score: an internationally derived scoring system from the surviving sepsis campaign database*. Crit Care Med (2014) 1.46
Drotrecogin alfa (activated) in an infant with gram-negative septic shock. J Intensive Care Med (2004) 1.42
Randomized controlled trial of inhaled nitric oxide for the treatment of microcirculatory dysfunction in patients with sepsis*. Crit Care Med (2014) 1.42
Inhaled nitric oxide: should it be used in acute respiratory distress syndrome? Crit Care Med (2006) 1.39
Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study. Intensive Care Med (2014) 1.38
Advances in pathogenesis and management of sepsis. Curr Opin Infect Dis (2007) 1.23
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit Care Med (2017) 1.15
Fluid resuscitation influences cardiovascular performance and mortality in a murine model of sepsis. Intensive Care Med (2008) 1.14
Infections and severe sepsis in solid-organ transplant patients admitted from a university-based ED. Am J Emerg Med (2004) 1.10
Reducing mortality in severe sepsis: the Surviving Sepsis Campaign. Clin Chest Med (2008) 1.01
The Surviving Sepsis Campaign: a history and a perspective. Surg Infect (Larchmt) (2010) 0.97
Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortality. Resuscitation (2008) 0.96
The International Sepsis Forum's controversies in sepsis: my initial vasopressor agent in septic shock is norepinephrine rather than dopamine. Crit Care (2002) 0.92
Ventricular dilation is associated with improved cardiovascular performance and survival in sepsis. Chest (2010) 0.91
Hemodynamic optimization of sepsis-induced tissue hypoperfusion. Crit Care (2006) 0.88
Targeting the lipopolysaccharides: still a matter of debate? Curr Opin Anaesthesiol (2008) 0.87
The impact of packed red blood cell transfusion on clinical outcomes in patients with septic shock treated with early goal directed therapy. Indian J Crit Care Med (2010) 0.87
Care of critically ill surgical patients using the 80-hour Accreditation Council of Graduate Medical Education work-week guidelines: a survey of current strategies. Am Surg (2006) 0.86
Systemic Inflammatory Response Syndrome Criteria for Severe Sepsis. N Engl J Med (2015) 0.86
Discordance between microcirculatory alterations and arterial pressure in patients with hemodynamic instability. J Crit Care (2012) 0.84
The Surviving Sepsis Campaign: 2013 and beyond. Chin Med J (Engl) (2013) 0.83
Porcine models of severe sepsis: emphasis on porcine peritonitis. Shock (2005) 0.83
Assessment of asymmetric lung disease in intensive care unit patients using vibration response imaging. Anesth Analg (2008) 0.83
Recent developments in the treatment of sepsis. Expert Opin Investig Drugs (2003) 0.82
Positive clinical impact of low tidal volume strategy. Crit Care Med (2005) 0.82
Treatment options for severe sepsis and septic shock. Expert Rev Anti Infect Ther (2006) 0.82
The International Sepsis Forum's frontiers in sepsis: High cardiac output should not be maintained in severe sepsis. Crit Care (2003) 0.82
Effectiveness of an inspiratory pressure-limited approach to mechanical ventilation in septic patients. Eur Respir J (2012) 0.81
Guidelines for severe infections: are they useful? Curr Opin Crit Care (2006) 0.81
Critical care medicine as a distinct product line with substantial financial profitability: the role of business planning. Crit Care Med (2004) 0.80
Targeting endotoxin in the treatment of sepsis. Subcell Biochem (2010) 0.79
Steroid therapy of septic shock: the decision is in the eye of the beholder. Crit Care Med (2008) 0.79
Other supportive therapies in sepsis: an evidence-based review. Crit Care Med (2004) 0.78
Shock overview. Semin Respir Crit Care Med (2004) 0.78
Case report: vibration response imaging findings following inadvertent esophageal intubation. Can J Anaesth (2008) 0.78
Talactoferrin in Severe Sepsis: Results From the Phase II/III Oral tAlactoferrin in Severe sepsIS Trial. Crit Care Med (2015) 0.77
Current treatment of severe sepsis. Curr Infect Dis Rep (2006) 0.77
Continuous cardiac index monitoring: A prospective observational study of agreement between a pulmonary artery catheter and a calibrated minimally invasive technique. Resuscitation (2009) 0.77
TAKEDA-143242 increased survival via reduced cytokines in porcine peritonitis. J Surg Res (2010) 0.77
A prospective multicenter cohort study of the association between global tissue hypoxia and coagulation abnormalities during early sepsis resuscitation. Crit Care Med (2010) 0.77
Crystalloids for fluid resuscitation in sepsis: where is the balance? Ann Intern Med (2014) 0.77
Arterial pressure optimization in the treatment of septic shock: a complex puzzle. Crit Care (2010) 0.77
Location of patients before transfer to a tertiary care intensive care unit: impact on outcome. J Crit Care (2008) 0.76
The authors reply. Crit Care Med (2013) 0.76
2008 update of international guidelines for the management of severe sepsis and septic shock: should we change our current clinical practice? Pol Arch Med Wewn (2008) 0.76
A new role for statins in sepsis. Crit Care (2013) 0.76
Contrasting treatment and outcomes of septic shock: presentation on hospital floors versus emergency department. Chin Med J (Engl) (2010) 0.75
Inhaled nitric oxide: another weapon in our armamentarium in the battle against acute hypoxic respiratory failure in preterm infants. Crit Care (2004) 0.75
Ethics roundtable: Using new, expensive drugs. Crit Care (2002) 0.75
The association of prior statin use in septic shock treated with early goal directed therapy. Eur J Emerg Med (2012) 0.75
A rose is a rose is a rose? Crit Care Med (2012) 0.75
The authors reply. Crit Care Med (2013) 0.75
The authors reply. Crit Care Med (2013) 0.75
Rebuttal from Drs Dellinger and Townsend. Chest (2013) 0.75
The authors reply. Crit Care Med (2013) 0.75
Severe sepsis in an emergency department: prevalence, rapid identification, and appropriate treatment. Crit Care Med (2007) 0.75
The authors reply. Crit Care Med (2014) 0.75
The authors reply. Crit Care Med (2013) 0.75
The authors reply. Crit Care Med (2013) 0.75
The authors reply. Crit Care Med (2015) 0.75
The authors reply. Crit Care Med (2013) 0.75
Endotoxin removal: how far from the evidence? From EUPHAS to EUPHRATES. Contrib Nephrol (2010) 0.75
Hemodynamic resuscitation in septic shock: cardiovascular support and adjunctive therapy. Curr Infect Dis Rep (2009) 0.75