Published in Cell on July 06, 2012
Type 2 alveolar cells are stem cells in adult lung. J Clin Invest (2013) 2.93
Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity. Nat Cell Biol (2013) 2.90
Stem cell plasticity. Plasticity of epithelial stem cells in tissue regeneration. Science (2014) 1.99
Tracing the cellular origin of cancer. Nat Cell Biol (2013) 1.75
Emerging interactions between skin stem cells and their niches. Nat Med (2014) 1.45
Epithelial stem cells and implications for wound repair. Semin Cell Dev Biol (2012) 1.35
SOX9: a stem cell transcriptional regulator of secreted niche signaling factors. Genes Dev (2014) 1.34
A matter of life and death: self-renewal in stem cells. EMBO Rep (2012) 1.30
Dietary and metabolic control of stem cell function in physiology and cancer. Cell Stem Cell (2014) 1.29
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling. Proc Natl Acad Sci U S A (2013) 1.26
Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche. Nat Rev Mol Cell Biol (2013) 1.13
Stem cell dynamics in the hair follicle niche. Semin Cell Dev Biol (2013) 1.08
Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia. Viruses (2015) 1.06
Eccrine sweat glands are major contributors to reepithelialization of human wounds. Am J Pathol (2012) 1.01
Restoration versus reconstruction: cellular mechanisms of skin, nerve and muscle regeneration compared. Regen Med Res (2013) 0.97
Sweat gland progenitors in development, homeostasis, and wound repair. Cold Spring Harb Perspect Med (2014) 0.97
Markers of epidermal stem cell subpopulations in adult mammalian skin. Cold Spring Harb Perspect Med (2014) 0.95
Clonal analysis reveals nerve-dependent and independent roles on mammalian hind limb tissue maintenance and regeneration. Proc Natl Acad Sci U S A (2014) 0.95
Quantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cells. Genes Dev (2016) 0.95
Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open (2013) 0.94
Allogeneic blood and bone marrow cells for the treatment of severe epidermolysis bullosa: repair of the extracellular matrix. Lancet (2013) 0.94
Three-dimensional co-culture of BM-MSCs and eccrine sweat gland cells in Matrigel promotes transdifferentiation of BM-MSCs. J Mol Histol (2015) 0.92
Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development (2014) 0.91
Epidermal development in mammals: key regulators, signals from beneath, and stem cells. Int J Mol Sci (2013) 0.90
Epithelial Skin Biology: Three Decades of Developmental Biology, a Hundred Questions Answered and a Thousand New Ones to Address. Curr Top Dev Biol (2016) 0.89
Bone morphogenetic protein signaling suppresses wound-induced skin repair by inhibiting keratinocyte proliferation and migration. J Invest Dermatol (2013) 0.89
Beyond the niche: tissue-level coordination of stem cell dynamics. Annu Rev Cell Dev Biol (2013) 0.88
Label retaining cells (LRCs) with myoepithelial characteristic from the proximal acinar region define stem cells in the sweat gland. PLoS One (2013) 0.88
Switching roles: the functional plasticity of adult tissue stem cells. EMBO J (2015) 0.87
Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development (2013) 0.87
Lineage analysis of epidermal stem cells. Cold Spring Harb Perspect Med (2014) 0.86
Analysis of histone H2BGFP retention in mouse submandibular gland reveals actively dividing stem cell populations. Stem Cells Dev (2014) 0.85
Role of CFTR in epithelial physiology. Cell Mol Life Sci (2016) 0.84
Label-retaining cells in the adult murine salivary glands possess characteristics of adult progenitor cells. PLoS One (2014) 0.83
Types or States? Cellular Dynamics and Regenerative Potential. Trends Cell Biol (2015) 0.82
Bifunctional ectodermal stem cells around the nail display dual fate homeostasis and adaptive wounding response toward nail regeneration. Proc Natl Acad Sci U S A (2014) 0.82
Cellular mechanisms of skin repair in humans and other mammals. J Cell Commun Signal (2016) 0.81
De novo epidermal regeneration using human eccrine sweat gland cells: higher competence of secretory over absorptive cells. J Invest Dermatol (2014) 0.80
The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches. Annu Rev Cell Dev Biol (2016) 0.78
Characterization of fetal keratinocytes, showing enhanced stem cell-like properties: a potential source of cells for skin reconstruction. Stem Cell Reports (2014) 0.78
A plethora of progenitors in the post-natal prostate. EMBO Rep (2012) 0.78
GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing. Sci Rep (2015) 0.78
Multipotent nestin-positive stem cells reside in the stroma of human eccrine and apocrine sweat glands and can be propagated robustly in vitro. PLoS One (2013) 0.78
The role of nuclear hormone receptors in cutaneous wound repair. Cell Biochem Funct (2014) 0.78
Cellular plasticity: 1712 to the present day. Curr Opin Cell Biol (2016) 0.77
Direct reprogramming of human fibroblasts into sweat gland-like cells. Cell Cycle (2015) 0.77
Comparative transcriptomic profiling of hydrogen peroxide signaling networks in zebrafish and human keratinocytes: Implications toward conservation, migration and wound healing. Sci Rep (2016) 0.77
Epidermal stem cells in orthopaedic regenerative medicine. Int J Mol Sci (2013) 0.76
Cell biology: More than skin deep. J Cell Biol (2015) 0.76
Fractional Skin Harvesting: Autologous Skin Grafting without Donor-site Morbidity. Plast Reconstr Surg Glob Open (2013) 0.76
Transplantation Into the Mouse Ovarian Fat Pad. J Vis Exp (2016) 0.75
T-Cadherin Expression in the Epidermis and Adnexal Structures of Normal Skin. Dermatopathology (Basel) (2016) 0.75
Insight into skin cell-based osteogenesis: a review. F1000Res (2017) 0.75
Epithelial Stem Cells of the Skin Contribute to the Histopathologic Umbrella-like Appearance in Actinic Keratosis. Yonago Acta Med (2014) 0.75
3D bioprinting matrices with controlled pore structure and release function guide in vitro self-organization of sweat gland. Sci Rep (2016) 0.75
Merkel cells are long-lived cells whose production is stimulated by skin injury. Dev Biol (2016) 0.75
Accelerating skin wound healing by M-CSF through generating SSEA-1 and -3 stem cells in the injured sites. Sci Rep (2016) 0.75
Skin appendage-derived stem cells: cell biology and potential for wound repair. Burns Trauma (2016) 0.75
Three-dimensional cell shapes and arrangements in human sweat glands as revealed by whole-mount immunostaining. PLoS One (2017) 0.75
Expression of S100A2 and S100P in human eccrine sweat glands and their application in differentiating secretory coil-like from duct-like structures in the 3D reconstituted eccrine sweat spheroids. J Mol Histol (2017) 0.75
A novel organotypic 3D sweat gland model with physiological functionality. PLoS One (2017) 0.75
Generation of a functional mammary gland from a single stem cell. Nature (2006) 18.30
Purification and unique properties of mammary epithelial stem cells. Nature (2006) 15.98
Defining the epithelial stem cell niche in skin. Science (2003) 14.93
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell (2004) 10.79
Capturing and profiling adult hair follicle stem cells. Nat Biotechnol (2004) 10.35
The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin. Proc Natl Acad Sci U S A (1999) 7.67
Distinct stem cells contribute to mammary gland development and maintenance. Nature (2011) 6.32
Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci U S A (1987) 6.30
An entire functional mammary gland may comprise the progeny from a single cell. Development (1998) 4.77
An atlas of mouse mammary gland development. J Mammary Gland Biol Neoplasia (2000) 2.73
A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus. J Cell Sci (2008) 2.06
Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo. Proc Natl Acad Sci U S A (2007) 1.97
The mammary microenvironment alters the differentiation repertoire of neural stem cells. Proc Natl Acad Sci U S A (2008) 1.77
Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development (2004) 1.53
EDA signaling and skin appendage development. Cell Cycle (2006) 1.39
Responses of the human eccrine sweat duct to controlled injury: growth center of the epidermal sweat duct unit. J Invest Dermatol (1954) 1.32
Adult corneal epithelium basal cells possess the capacity to activate epidermal, pilosebaceous and sweat gland genetic programs in response to embryonic dermal stimuli. Development (2000) 1.20
Anhidrosis and absence of sweat glands in mice hemizygous for the Tabby gene: supportive evidence for the hypothesis of homology between Tabby and human anhidrotic (hypohidrotic) ectodermal dysplasia (Christ-Siemens-Touraine syndrome). J Invest Dermatol (1986) 1.18
Characterization of a novel human type II epithelial keratin K1b, specifically expressed in eccrine sweat glands. J Invest Dermatol (2005) 1.15
Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1. Proc Natl Acad Sci U S A (2012) 1.13
Human eccrine sweat gland cells can reconstitute a stratified epidermis. J Invest Dermatol (2010) 1.10
Re-epithelialization of porcine skin by the sweat apparatus. J Invest Dermatol (1998) 1.09
Localization of aquaporin-5 in sweat glands and functional analysis using knockout mice. J Physiol (2002) 1.08
Human sweat gland myoepithelial cells express a unique set of cytokeratins and reveal the potential for alternative epithelial and mesenchymal differentiation states in culture. J Cell Sci (1999) 1.04
Requirement for Shh and Fox family genes at different stages in sweat gland development. Hum Mol Genet (2009) 1.03
Dermatology: the eccrine sweat glands. Annu Rev Med (1961) 1.01
Sox9, more than a marker of the outer root sheath: spatiotemporal expression pattern during human cutaneous embryogenesis. J Cutan Pathol (2009) 1.00
Changes of expression of intermediate filament proteins during ontogenesis of eccrine sweat glands. J Invest Dermatol (1992) 0.92
Response of the human eccrine sweat duct to dermal injury. J Invest Dermatol (1956) 0.89
Glucose metabolism of the isolated eccrine sweat gland. II. The relation between glucose metabolism and sodium transport. J Clin Invest (1973) 0.84
cAMP-dependent Cl(-) channel protein (CFTR) and its mRNA are expressed in the secretory portion of human eccrine sweat gland. J Histochem Cytochem (2000) 0.80
Defining the epithelial stem cell niche in skin. Science (2003) 14.93
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell (2004) 10.79
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89
Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95
Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature (2005) 6.67
Distinct stem cells contribute to mammary gland development and maintenance. Nature (2011) 6.32
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet (2006) 6.30
A skin microRNA promotes differentiation by repressing 'stemness'. Nature (2008) 5.66
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell (2009) 5.51
A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell (2009) 5.40
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med (2014) 5.37
Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell (2008) 5.02
Sticky business: orchestrating cellular signals at adherens junctions. Cell (2003) 4.91
Links between signal transduction, transcription and adhesion in epithelial bud development. Nature (2003) 4.88
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell (2012) 4.41
Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol (2002) 4.29
Molecular dissection of mesenchymal-epithelial interactions in the hair follicle. PLoS Biol (2005) 4.27
Dynamics between stem cells, niche, and progeny in the hair follicle. Cell (2011) 4.14
Epithelial stem cells: turning over new leaves. Cell (2007) 4.10
Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev Cell (2002) 4.01
Epidermal stem cells of the skin. Annu Rev Cell Dev Biol (2006) 3.92
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature (2011) 3.90
Tcf3 governs stem cell features and represses cell fate determination in skin. Cell (2006) 3.88
NFATc1 balances quiescence and proliferation of skin stem cells. Cell (2008) 3.81
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell (2006) 3.79
Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables. Nat Cell Biol (2003) 3.77
Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol (2004) 3.70
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev (2005) 3.67
Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature (2011) 3.64
Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature (2011) 3.56
Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia. Cancer Cell (2007) 3.55
Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev (2006) 3.51
A role for skin gammadelta T cells in wound repair. Science (2002) 3.51
The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet (2013) 3.43
BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC. Oncogene (2003) 3.34
Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling. Proc Natl Acad Sci U S A (2007) 3.16
In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am J Physiol Lung Cell Mol Physiol (2003) 3.08
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol (2008) 3.07
GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev (2003) 2.97
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell (2008) 2.94
Stem cells in the skin: waste not, Wnt not. Genes Dev (2003) 2.80
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell (2011) 2.80
Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics. J Cell Biol (2007) 2.79
Alpha-catenin: at the junction of intercellular adhesion and actin dynamics. Nat Rev Mol Cell Biol (2004) 2.79
Lhx2 maintains stem cell character in hair follicles. Science (2006) 2.78
Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am J Hum Genet (2003) 2.73
Catenins: keeping cells from getting their signals crossed. Dev Cell (2006) 2.70
Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (2002) 2.69
p120-catenin mediates inflammatory responses in the skin. Cell (2006) 2.66
ACF7: an essential integrator of microtubule dynamics. Cell (2003) 2.66
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol Cell (2012) 2.66
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA. J Cell Biol (2003) 2.65
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev (2011) 2.63
The hair cycle. J Cell Sci (2006) 2.58
DGCR8-dependent microRNA biogenesis is essential for skin development. Proc Natl Acad Sci U S A (2008) 2.49
RNAi screens in mice identify physiological regulators of oncogenic growth. Nature (2013) 2.46
BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties. Genes Dev (2008) 2.41
Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3β. Cell (2011) 2.36
Tcf3: a transcriptional regulator of axis induction in the early embryo. Development (2003) 2.26
Stem cells of the skin epithelium. Proc Natl Acad Sci U S A (2003) 2.20
Desmoplakin: an unexpected regulator of microtubule organization in the epidermis. J Cell Biol (2007) 2.16
The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy. Immunity (2012) 2.15
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A (2003) 2.14
Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling. Proc Natl Acad Sci U S A (2011) 2.13
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc Natl Acad Sci U S A (2011) 2.08
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat Genet (2009) 2.07
Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. J Clin Invest (2009) 2.06
Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat Med (2010) 2.01