Clinical applications for microRNAs in cancer.

PubWeight™: 2.05‹?› | Rank: Top 2%

🔗 View Article (PMID 23212103)

Published in Clin Pharmacol Ther on December 05, 2012

Authors

S P Nana-Sinkam1, C M Croce

Author Affiliations

1: Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA. Patrick.Nana-Sinkam@osumc.edu

Articles citing this

MicroRNA-17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways. EMBO J (2013) 2.01

Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer. Proc Natl Acad Sci U S A (2013) 1.32

miRNA dysregulation in cancer: towards a mechanistic understanding. Front Genet (2014) 1.25

The role of epithelial-mesenchymal transition programming in invasion and metastasis: a clinical perspective. Cancer Manag Res (2013) 1.22

The Tumor Suppressor Roles of miR-433 and miR-127 in Gastric Cancer. Int J Mol Sci (2013) 1.21

The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy. Oncotarget (2015) 1.18

Global population-specific variation in miRNA associated with cancer risk and clinical biomarkers. BMC Med Genomics (2014) 1.13

miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma. Oncotarget (2014) 1.12

miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma. Genes Dev (2015) 1.08

MicroRNAs and the cancer phenotype: profiling, signatures and clinical implications. Genome Med (2013) 1.05

The role of microRNAs in breast cancer stem cells. Int J Mol Sci (2013) 1.04

MicroRNAs in pathogenesis of breast cancer: Implications in diagnosis and treatment. World J Clin Oncol (2014) 1.03

Upregulation of microRNA-25 associates with prognosis in hepatocellular carcinoma. Diagn Pathol (2014) 1.02

Bioinformatic tools for microRNA dissection. Nucleic Acids Res (2015) 1.02

Neuronal dark matter: the emerging role of microRNAs in neurodegeneration. Front Cell Neurosci (2013) 1.02

Breast cancer intrinsic subtype classification, clinical use and future trends. Am J Cancer Res (2015) 1.00

Serum exosomal microRNAs as novel biomarkers for hepatocellular carcinoma. Exp Mol Med (2015) 0.99

Diminished skeletal muscle microRNA expression with aging is associated with attenuated muscle plasticity and inhibition of IGF-1 signaling. FASEB J (2014) 0.98

MicroRNA 375 mediates palmitate-induced enteric neuronal damage and high-fat diet-induced delayed intestinal transit in mice. Gastroenterology (2013) 0.97

Epigenetic modifications and diabetic retinopathy. Biomed Res Int (2013) 0.97

Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells. PLoS Pathog (2015) 0.97

The locus of microRNA-10b: a critical target for breast cancer insurgence and dissemination. Cell Cycle (2013) 0.96

Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma. Biomed Res Int (2014) 0.94

MicroRNA regulation and therapeutic targeting of survivin in cancer. Am J Cancer Res (2014) 0.93

MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells. BMC Cancer (2015) 0.93

Upregulation of miR-21 in cisplatin resistant ovarian cancer via JNK-1/c-Jun pathway. PLoS One (2014) 0.93

The identification of novel targets of miR-16 and characterization of their biological functions in cancer cells. Mol Cancer (2013) 0.92

PAX6, a novel target of microRNA-7, promotes cellular proliferation and invasion in human colorectal cancer cells. Dig Dis Sci (2013) 0.90

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics. Cancer Med (2016) 0.89

Noncoding RNA blockade of autophagy is therapeutic in medullary thyroid cancer. Cancer Med (2014) 0.87

Tissue slide-based microRNA characterization of tumors: how detailed could diagnosis become for cancer medicine? Expert Rev Mol Diagn (2014) 0.87

MiR-126 regulated breast cancer cell invasion by targeting ADAM9. Int J Clin Exp Pathol (2015) 0.87

microRNAs: short non-coding bullets of gain of function mutant p53 proteins. Oncoscience (2014) 0.86

Regulation of cancer metastasis by microRNAs. J Biomed Sci (2015) 0.86

MicroRNA-27a-3p Is a Negative Regulator of Lung Fibrosis by Targeting Myofibroblast Differentiation. Am J Respir Cell Mol Biol (2016) 0.86

Current status of miRNA-targeting therapeutics and preclinical studies against gastroenterological carcinoma. Mol Cell Ther (2013) 0.86

MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression. Mol Cancer Ther (2014) 0.85

Survivin-targeting Artificial MicroRNAs Mediated by Adenovirus Suppress Tumor Activity in Cancer Cells and Xenograft Models. Mol Ther Nucleic Acids (2014) 0.85

Targeting Intracellular Cholesterol is a Novel Therapeutic Strategy for Cancer Treatment. J Cancer Sci Ther (2014) 0.84

Profiling the microRNA Expression in Human iPS and iPS-derived Retinal Pigment Epithelium. Cancer Inform (2014) 0.84

Combined microRNA-340 and ROCK1 mRNA profiling predicts tumor progression and prognosis in pediatric osteosarcoma. Int J Mol Sci (2014) 0.84

miR-125b inhibits Connexin43 and promotes glioma growth. Cell Mol Neurobiol (2013) 0.83

Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology. BMC Cancer (2014) 0.83

miR in melanoma development: miRNAs and acquired hallmarks of cancer in melanoma. Physiol Genomics (2013) 0.83

Down-regulation of microRNA-124 is correlated with tumor metastasis and poor prognosis in patients with lung cancer. Int J Clin Exp Pathol (2015) 0.83

miR-638 regulates gene expression networks associated with emphysematous lung destruction. Genome Med (2013) 0.82

Correlation of MicroRNA 132 Up-regulation with an Unfavorable Clinical Outcome in Patients with Primary Glioblastoma Multiforme Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide Chemotherapy. Transl Oncol (2013) 0.82

Managing Pancreatic Adenocarcinoma: A Special Focus in MicroRNA Gene Therapy. Int J Mol Sci (2016) 0.82

Stromal expression of miR-21 identifies high-risk group in triple-negative breast cancer. Am J Pathol (2014) 0.82

RNA regulation of the immune system. Immunol Rev (2013) 0.82

Identification of miR-200a as a novel suppressor of connexin 43 in breast cancer cells. Biosci Rep (2015) 0.82

miR-21 promotes the differentiation of hair follicle-derived neural crest stem cells into Schwann cells. Neural Regen Res (2014) 0.82

MicroRNA signatures as biomarkers and therapeutic target for CNS embryonal tumors: the pros and the cons. Int J Mol Sci (2014) 0.81

Profile of circulating microRNAs in fibromyalgia and their relation to symptom severity: an exploratory study. Rheumatol Int (2014) 0.81

MicroRNAs as possible biomarkers for diagnosis and prognosis of hepatitis B- and C-related-hepatocellular-carcinoma. World J Gastroenterol (2016) 0.81

MicroRNA-31 Promotes Skin Wound Healing by Enhancing Keratinocyte Proliferation and Migration. J Invest Dermatol (2015) 0.80

The oncomiR miR-197 is a novel prognostic indicator for non-small cell lung cancer patients. Br J Cancer (2015) 0.80

An 11-nt sequence polymorphism at the 3'UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell culture. Am J Physiol Lung Cell Mol Physiol (2014) 0.80

Expression of tumor suppressive microRNA-34a is associated with a reduced risk of bladder cancer recurrence. Int J Cancer (2015) 0.80

Serum miR-125b is a non-invasive predictive biomarker of the pre-operative chemoradiotherapy responsiveness in patients with rectal adenocarcinoma. Oncotarget (2016) 0.79

Hsa-microRNA-181a is a regulator of a number of cancer genes and a biomarker for endometrial carcinoma in patients: a bioinformatic and clinical study and the therapeutic implication. Drug Des Devel Ther (2015) 0.79

Effect of miR-340 on gastric cancer cell proliferation and apoptosis. Int J Clin Exp Pathol (2015) 0.78

Understanding microRNA-mediated gene regulatory networks through mathematical modelling. Nucleic Acids Res (2016) 0.78

Biogenesis, evolution and functional targets of microRNA-125a. Mol Genet Genomics (2013) 0.78

Microrna expression signatures predict patient progression and disease outcome in pediatric embryonal central nervous system neoplasms. J Hematol Oncol (2014) 0.78

Exosomes isolation and characterization in serum is feasible in non-small cell lung cancer patients: critical analysis of evidence and potential role in clinical practice. Oncotarget (2016) 0.78

Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis? Mol Ther (2015) 0.78

Novel MicroRNA Reporter Uncovers Repression of Let-7 by GSK-3β. PLoS One (2013) 0.78

Prediction of potential cancer-risk regions based on transcriptome data: towards a comprehensive view. PLoS One (2014) 0.78

Impact of Nutrition on Non-Coding RNA Epigenetics in Breast and Gynecological Cancer. Front Nutr (2015) 0.77

Can hyperthermic intraperitoneal chemotherapy efficiency be improved by blocking the DNA repair factor COP9 signalosome? Int J Colorectal Dis (2014) 0.77

To Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAs. Int J Biol Sci (2015) 0.77

MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknown. J Hematol Oncol (2015) 0.77

Unraveling the 'TGF-β paradox' one metastamir at a time. Breast Cancer Res (2013) 0.77

MiR-1180 promotes apoptotic resistance to human hepatocellular carcinoma via activation of NF-κB signaling pathway. Sci Rep (2016) 0.77

Integrated miRNA profiling and bioinformatics analyses reveal potential causative miRNAs in gastric adenocarcinoma. Oncotarget (2015) 0.76

Inflamma-miRs in Aging and Breast Cancer: Are They Reliable Players? Front Med (Lausanne) (2015) 0.76

A systematic in silico mining of the mechanistic implications and therapeutic potentials of estrogen receptor (ER)-α in breast cancer. PLoS One (2014) 0.76

Identification of Aberrantly Expressed miRNAs in Gastric Cancer. Gastroenterol Res Pract (2014) 0.76

MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy. Mol Ther (2016) 0.76

Assessing the clinical value of microRNAs in formalin-fixed paraffin-embedded liposarcoma tissues: Overexpressed miR-155 is an indicator of poor prognosis. Oncotarget (2016) 0.75

ApoptomiRs of Breast Cancer: Basics to Clinics. Front Genet (2016) 0.75

MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase. Oncotarget (2016) 0.75

A Versatile Tool for Stable Inhibition of microRNA Activity. Biology (Basel) (2013) 0.75

Profiles of miRNAs matched to biology in aromatase inhibitor resistant breast cancer. Oncotarget (2016) 0.75

miR-223 decreases cell proliferation and enhances cell apoptosis in acute myeloid leukemia via targeting FBXW7. Oncol Lett (2016) 0.75

Biomarkers for non-muscle invasive bladder cancer: Current tests and future promise. Indian J Urol (2015) 0.75

Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry. Hum Genet (2016) 0.75

MicroRNA based treatment of cardiomyopathy: not all dystrophies are created equal. J Am Heart Assoc (2013) 0.75

Downregulation of LSD1 suppresses the proliferation, tumorigenicity and invasion of papillary thyroid carcinoma K1 cells. Oncol Lett (2016) 0.75

Associations of deregulation of mir-365 and its target mRNA TTF-1 and survival in patients with NSCLC. Int J Clin Exp Pathol (2015) 0.75

miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathway. BMC Cell Biol (2017) 0.75

MicroRNAs Regulate Cytokine Responses in Gingival Epithelial Cells. Infect Immun (2016) 0.75

Export of microRNAs: A Bridge between Breast Carcinoma and Their Neighboring Cells. Front Oncol (2016) 0.75

Targeted imaging and induction of apoptosis of drug-resistant hepatoma cells by miR-122-loaded graphene-InP nanocompounds. J Nanobiotechnology (2017) 0.75

A MicroRNA Panel in Pancreatic Cyst Fluid for the Risk Stratification of Pancreatic Cysts in a Prospective Cohort. Mol Ther Nucleic Acids (2016) 0.75

miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma. Blood (2017) 0.75

Articles by these authors

(truncated to the top 100)

The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell (1996) 15.19

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc Natl Acad Sci U S A (1982) 11.15

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science (1984) 8.80

Involvement of the bcl-2 gene in human follicular lymphoma. Science (1985) 8.19

Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun (2005) 7.50

The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science (1985) 6.63

Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature (1984) 5.85

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci U S A (1986) 5.54

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell (1992) 5.39

Nucleotide sequence of cloned cDNA of human c-myc oncogene. Nature (1983) 4.83

Chromosomal location of the genes for human immunoglobulin heavy chains. Proc Natl Acad Sci U S A (1979) 4.52

Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells. Proc Natl Acad Sci U S A (1977) 4.30

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma. Oncogene (2008) 4.11

MicroRNA deregulation in human thyroid papillary carcinomas. Endocr Relat Cancer (2006) 4.11

Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses. Blood (1998) 4.07

miR-15a and miR-16-1 in cancer: discovery, function and future perspectives. Cell Death Differ (2009) 3.94

Transcriptionally active c-myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia. Proc Natl Acad Sci U S A (1983) 3.90

Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas. Science (1983) 3.82

Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription. Proc Natl Acad Sci U S A (1983) 3.75

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc Natl Acad Sci U S A (2000) 3.69

Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science (1984) 3.64

Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt. Proc Natl Acad Sci U S A (1983) 3.53

Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma. Proc Natl Acad Sci U S A (1983) 3.46

Assignment of the genes for human lambda immunoglobulin chains to chromosome 22. Nature (1981) 3.43

Differential expression of the normal and of the translocated human c-myc oncogenes in B cells. Proc Natl Acad Sci U S A (1983) 3.43

Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphoma. Science (1983) 3.40

Translocation of immunoglobulin VH genes in Burkitt lymphoma. Proc Natl Acad Sci U S A (1982) 3.30

Specific microRNAs are downregulated in human thyroid anaplastic carcinomas. Oncogene (2007) 3.29

Inactivation of Bcl-2 by phosphorylation. Proc Natl Acad Sci U S A (1995) 3.13

microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. Oncogene (2011) 3.02

Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation. Nature (1985) 2.91

MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia. Oncogene (2007) 2.79

Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax. Oncogene (1997) 2.69

Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7. Proc Natl Acad Sci U S A (1973) 2.63

Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene. Science (2001) 2.61

FRA3B and other common fragile sites: the weakest links. Nat Rev Cancer (2001) 2.61

The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis. Cancer Res (1999) 2.56

Localization of gene for human p53 tumour antigen to band 17p13. Nature (1986) 2.56

The alpha-spectrin gene is on chromosome 1 in mouse and man. Proc Natl Acad Sci U S A (1985) 2.53

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex. Proc Natl Acad Sci U S A (1998) 2.52

Bcl2 is the guardian of microtubule integrity. Cancer Res (1997) 2.51

Tcl1 enhances Akt kinase activity and mediates its nuclear translocation. Proc Natl Acad Sci U S A (2000) 2.48

elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints. Science (1989) 2.48

Mch3, a novel human apoptotic cysteine protease highly related to CPP32. Cancer Res (1995) 2.47

MicroRNAs and chromosomal abnormalities in cancer cells. Oncogene (2006) 2.47

Somatic cell hybrids producing antibodies specific for the tumor antigen of simian virus 40. Proc Natl Acad Sci U S A (1978) 2.47

Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase. Biochemistry (1996) 2.46

Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma. Proc Natl Acad Sci U S A (1989) 2.45

MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer. Oncogene (2008) 2.44

Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality. Oncogene (2001) 2.42

Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene. Cancer Res (2001) 2.41

Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas. Proc Natl Acad Sci U S A (1987) 2.40

Effect of environmental pH on the efficiency of cellular hybridization. Proc Natl Acad Sci U S A (1972) 2.39

Repertoire of antiviral antibodies expressed by somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 2.38

A potential role for interleukin-15 in the regulation of human natural killer cell survival. J Clin Invest (1997) 2.37

The FHIT gene 3p14.2 is abnormal in lung cancer. Cell (1996) 2.36

Replacement of Fhit in cancer cells suppresses tumorigenicity. Proc Natl Acad Sci U S A (1997) 2.36

Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation. Science (1987) 2.36

Gene for alpha-chain of human T-cell receptor: location on chromosome 14 region involved in T-cell neoplasms. Science (1985) 2.33

Production of human hybridomas secreting antibodies to measles virus. Nature (1980) 2.32

Down-regulation of bcl-2 by p53 in breast cancer cells. Cancer Res (1994) 2.31

Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells. Proc Natl Acad Sci U S A (1992) 2.28

Chromosomal localization of the human homolog (c-sis) of the simian sarcoma virus onc gene. Science (1982) 2.27

Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22. Proc Natl Acad Sci U S A (1988) 2.26

Control of expression of histocompatibility antigens (H-2) and beta 2-microglobulin in F9 teratocarcinoma stem cells. Proc Natl Acad Sci U S A (1981) 2.22

Selective suppression of the transcription of ribosomal genes in mouse-human hybrid cells. J Cell Physiol (1979) 2.21

Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7. J Biol Chem (2001) 2.19

Muir-Torre-like syndrome in Fhit-deficient mice. Proc Natl Acad Sci U S A (2000) 2.15

Molecular analysis of mbcl-2: structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma. Cell (1987) 2.12

Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia. Proc Natl Acad Sci U S A (1989) 2.11

GOK: a gene at 11p15 involved in rhabdomyosarcoma and rhabdoid tumor development. Cancer Res (1997) 2.11

Taxol induces bcl-2 phosphorylation and death of prostate cancer cells. Cancer Res (1996) 2.09

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms. Oncogene (2000) 2.08

A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2. J Biol Chem (2000) 2.08

Role of the high mobility group A proteins in human lipomas. Carcinogenesis (2001) 2.08

The gene encoding the T-cell surface protein T4 is located on human chromosome 12. Proc Natl Acad Sci U S A (1986) 2.08

The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining. Nature (1986) 2.07

Chromosomal assignment of the human homologues of feline sarcoma virus and avian myeloblastosis virus onc genes. Proc Natl Acad Sci U S A (1982) 2.06

Characterization of the protein product of bcl-2, the gene involved in human follicular lymphoma. Oncogene (1987) 2.06

Identification of the TCL1 gene involved in T-cell malignancies. Proc Natl Acad Sci U S A (1994) 2.02

The role of the FHIT/FRA3B locus in cancer. Annu Rev Genet (1998) 2.01

Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11. Cancer Res (1996) 1.99

MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene (2010) 1.97

Loss of FHIT function in lung cancer and preinvasive bronchial lesions. Cancer Res (1998) 1.96

Loss of mouse chromosomes in somatic cell hybrids between HT-1080 human fibrosarcoma cells and mouse peritioneal macrophages. Proc Natl Acad Sci U S A (1976) 1.96

Role of chromosome translocations in human neoplasia. Cell (1987) 1.94

Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia. Cancer Res (2001) 1.93

Oncogene activation by chromosome translocation in human malignancy. Annu Rev Genet (1987) 1.91

Somatic cell hybrids between mouse peritoneal macrophages and SV40-transformed human cells. I. Positive control of the transformed phenotype by the human chromosome 7 carrying the SV40 genome. J Exp Med (1974) 1.91

Cloning and sequencing of a c-myc oncogene in a Burkitt's lymphoma cell line that is translocated to a germ line alpha switch region. Mol Cell Biol (1985) 1.90

Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases. Proc Natl Acad Sci U S A (1993) 1.89

Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) chromosome translocations. Cancer Res (1991) 1.88

Molecular cloning and nucleotide sequence of a full-length cDNA for human alpha enolase. Proc Natl Acad Sci U S A (1986) 1.87

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis. J Biol Chem (1997) 1.86

Deregulated expression of TCL1 causes T cell leukemia in mice. Proc Natl Acad Sci U S A (1998) 1.86

Molecular basis of human B cell neoplasia. Blood (1985) 1.85

Localization of the gene encoding human erythroid-potentiating activity to chromosome region Xp11.1----Xp11.4. Am J Hum Genet (1986) 1.84

The structure and nucleotide sequence of the 5' end of the human c-myc oncogene. Proc Natl Acad Sci U S A (1983) 1.84

Human regulatory gene for inducible tyrosine aminotransferase in rat-human hybrids. Proc Natl Acad Sci U S A (1973) 1.84

Human TCR-gamma+/delta+, CD8+ T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion. J Exp Med (1989) 1.82