Published in Proc Natl Acad Sci U S A on March 28, 2000
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Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles. J Cell Biol (2005) 1.11
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Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A (2004) 1.08
ROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice. Proc Natl Acad Sci U S A (2013) 1.05
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Protein kinase B phosphorylates AHNAK and regulates its subcellular localization. J Cell Biol (2001) 1.04
Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice. Blood (2012) 1.00
Phosphoinositol lipids bind to phosphatidylinositol 3 (PI3)-kinase enhancer GTPase and mediate its stimulatory effect on PI3-kinase and Akt signalings. Proc Natl Acad Sci U S A (2005) 0.99
Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications. Am J Pathol (2010) 0.99
High TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemia. Blood (2007) 0.98
CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation. Leukemia (2010) 0.98
Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia. Blood (2009) 0.98
Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies. Blood (2011) 0.96
Targeting the PI3-kinase/Akt/mTOR signaling pathway. Surg Oncol Clin N Am (2013) 0.94
TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation. Proc Natl Acad Sci U S A (2007) 0.94
Role of AKT signaling in DNA repair and clinical response to cancer therapy. Neuro Oncol (2014) 0.94
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation. J Biol Chem (2008) 0.93
T cell leukemia I oncogene expression depends on the presence of Epstein-Barr virus in the virus-carrying Burkitt lymphoma lines. Proc Natl Acad Sci U S A (2003) 0.92
Identification, characterization and metagenome analysis of oocyte-specific genes organized in clusters in the mouse genome. BMC Genomics (2005) 0.92
TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2015) 0.90
Nuclear orphan receptor TLX induces Oct-3/4 for the survival and maintenance of adult hippocampal progenitors upon hypoxia. J Biol Chem (2010) 0.89
An Akt-dependent increase in canonical Wnt signaling and a decrease in sclerostin protein levels are involved in strontium ranelate-induced osteogenic effects in human osteoblasts. J Biol Chem (2011) 0.89
The role of the dysfunctional akt-related pathway in cancer: establishment and maintenance of a malignant cell phenotype, resistance to therapy, and future strategies for drug development. Scientifica (Cairo) (2013) 0.89
Accelerated development of chronic lymphocytic leukemia in New Zealand Black mice expressing a low level of interferon regulatory factor 4. J Biol Chem (2013) 0.88
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia. Blood (2011) 0.86
Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. Blood (2006) 0.86
Therapeutic Implications of Targeting AKT Signaling in Melanoma. Enzyme Res (2011) 0.85
Interaction between TCL1 and Epac1 in the activation of Akt kinases in plasma membranes and nuclei of 8-CPT-2-O-Me-cAMP-stimulated macrophages. Cell Signal (2007) 0.82
Candidate tumor suppressor and pVHL partner Jade-1 binds and inhibits AKT in renal cell carcinoma. Cancer Res (2013) 0.82
PTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome. J Clin Endocrinol Metab (2012) 0.81
The TCL1A oncoprotein interacts directly with the NF-kappaB inhibitor IkappaB. PLoS One (2009) 0.80
Backbone dynamics and solution structure refinement of the 15N-labeled human oncogenic protein p13MTCP1: comparison with X-ray data. J Biomol NMR (2000) 0.80
Pediatric T-cell prolymphocytic leukemia with an isolated 12(p13) deletion and aberrant CD117 expression. Exp Hematol Oncol (2012) 0.80
miR deregulation in CLL. Adv Exp Med Biol (2013) 0.79
Functional analysis of Tcl1 using Tcl1-deficient mouse embryonic stem cells. PLoS One (2013) 0.79
Telomerase activity, apoptosis and cell cycle progression in ataxia telangiectasia lymphocytes expressing TCL1. Br J Cancer (2003) 0.78
Inherited predisposition to chronic lymphocytic leukemia. Expert Rev Hematol (2008) 0.78
TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia. Cell Death Dis (2016) 0.78
miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model. Oncotarget (2015) 0.78
TCL1A and ATM are co-expressed in chronic lymphocytic leukemia cells without deletion of 11q. Haematologica (2012) 0.77
The long journey of TCL1 transgenic mice: lessons learned in the last 15 years. Gene Expr (2015) 0.76
Protooncogene TCL1b functions as an Akt kinase co-activator that exhibits oncogenic potency in vivo. Oncogenesis (2013) 0.76
The emerging roles of Oct4 in tumor-initiating cells. Am J Physiol Cell Physiol (2015) 0.76
Multiple-Localization and Hub Proteins. PLoS One (2016) 0.75
The regulatory interaction of EVI1 with the TCL1A oncogene impacts cell survival and clinical outcome in CLL. Leukemia (2015) 0.75
Direct comparison of distinct naive pluripotent states in human embryonic stem cells. Nat Commun (2017) 0.75
Absence of TCL1A expression is a useful diagnostic feature in splenic marginal zone lymphoma. Virchows Arch (2012) 0.75
Integrated Cellular and Plasma Proteomics of Contrasting B-cell Cancers Reveals Common, Unique and Systemic Signatures. Mol Cell Proteomics (2017) 0.75
Non-canonical Activation of Akt in Serum-Stimulated Fibroblasts, Revealed by Comparative Modeling of Pathway Dynamics. PLoS Comput Biol (2015) 0.75
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