Published in Genes Dev on January 01, 2013
Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer. Cell (2014) 2.47
A feedforward regulatory loop between HuR and the long noncoding RNA linc-MD1 controls early phases of myogenesis. Mol Cell (2014) 1.24
MicroRNA-7a regulates pancreatic β cell function. J Clin Invest (2014) 1.18
microRNAs: key triggers of neuronal cell fate. Front Cell Neurosci (2014) 1.02
Outside the coding genome, mammalian microRNAs confer structural and functional complexity. Sci Signal (2015) 0.97
Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128. Mol Cancer (2014) 0.96
MicroRNA in teleost fish. Genome Biol Evol (2014) 0.93
Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation. Cell Rep (2014) 0.90
Terminal loop-mediated regulation of miRNA biogenesis: selectivity and mechanisms. Biochem Soc Trans (2013) 0.90
Lin28a regulates neuronal differentiation and controls miR-9 production. Nat Commun (2014) 0.88
miRNA gene counts in chromosomes vary widely in a species and biogenesis of miRNA largely depends on transcription or post-transcriptional processing of coding genes. Front Genet (2014) 0.86
Zika Fetal Neuropathogenesis: Etiology of a Viral Syndrome. PLoS Negl Trop Dis (2016) 0.84
Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility. J Clin Invest (2017) 0.84
miRNA Control of Tissue Repair and Regeneration. Am J Pathol (2015) 0.83
H19 Long Noncoding RNA Regulates Intestinal Epithelial Barrier Function via MicroRNA 675 by Interacting with RNA-Binding Protein HuR. Mol Cell Biol (2016) 0.83
MicroRNA-7: a promising new target in cancer therapy. Cancer Cell Int (2015) 0.82
Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma. EMBO J (2015) 0.82
Clinical Potential of microRNA-7 in Cancer. J Clin Med (2015) 0.82
The miR-7 identified from collagen biomaterial-based three-dimensional cultured cells regulates neural stem cell differentiation. Stem Cells Dev (2013) 0.82
Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers. Mol Cell Biol (2015) 0.81
MiR-590-5p inhibits colorectal cancer angiogenesis and metastasis by regulating nuclear factor 90/vascular endothelial growth factor A axis. Cell Death Dis (2016) 0.79
TLR9 signaling repressed tumor suppressor miR-7 expression through up-regulation of HuR in human lung cancer cells. Cancer Cell Int (2013) 0.79
Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic Targets. Clin Cancer Res (2017) 0.78
Suppression of MicroRNA-7 (miR-7) Biogenesis by Nuclear Factor 90-Nuclear Factor 45 Complex (NF90-NF45) Controls Cell Proliferation in Hepatocellular Carcinoma. J Biol Chem (2016) 0.78
Traumatic brain injury increases levels of miR-21 in extracellular vesicles: implications for neuroinflammation. FEBS Open Bio (2016) 0.77
DROSHA targets its own transcript to modulate alternative splicing. RNA (2017) 0.77
Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases. Nucleic Acids Res (2016) 0.76
MicroRNA-7 Deficiency Ameliorates the Pathologies of Acute Lung Injury through Elevating KLF4. Front Immunol (2016) 0.76
RNA-Binding Proteins in the Regulation of miRNA Activity: A Focus on Neuronal Functions. Biomolecules (2015) 0.76
MiRNAs in β-Cell Development, Identity, and Disease. Front Genet (2017) 0.75
Evidence of purifying selection and co-evolution at the fold-back arm of the novel precursor microRNA159 gene in Phalaenopsis Species (Orchidaceae). PLoS One (2014) 0.75
Identification of linc-NeD125, a novel long non coding RNA that hosts miR-125b-1 and negatively controls proliferation of human neuroblastoma cells. RNA Biol (2015) 0.75
MiR-7a is an important mediator in Fas-associated protein with death domain (FADD)-regulated expression of focal adhesion kinase (FAK). Oncotarget (2016) 0.75
The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA. Oncotarget (2016) 0.75
Silencing CDR1as inhibits colorectal cancer progression through regulating microRNA-7. Onco Targets Ther (2017) 0.75
The nuclear RNase III Drosha initiates microRNA processing. Nature (2003) 35.49
An extensive class of small RNAs in Caenorhabditis elegans. Science (2001) 34.17
A mammalian microRNA expression atlas based on small RNA library sequencing. Cell (2007) 34.03
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science (2001) 31.33
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics (2002) 30.58
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature (2000) 23.17
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev (2001) 21.82
The Microprocessor complex mediates the genesis of microRNAs. Nature (2004) 17.70
The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet (2010) 15.87
microRNA functions. Annu Rev Cell Dev Biol (2007) 15.74
Processing of primary microRNAs by the Microprocessor complex. Nature (2004) 14.59
Selective blockade of microRNA processing by Lin28. Science (2008) 14.39
Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem (2010) 12.06
The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev (2004) 11.58
Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol (2009) 11.50
Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev (2006) 11.04
Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia (2007) 10.74
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell (2008) 8.32
EGFR and cancer prognosis. Eur J Cancer (2001) 7.52
A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol (2008) 7.35
MicroRNAs and cancer: short RNAs go a long way. Cell (2009) 7.25
The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol (2004) 6.56
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell (2009) 5.99
The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol (2007) 5.91
Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J Biol Chem (1996) 5.82
Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification. Bioinformatics (2004) 4.88
microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res (2008) 4.81
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature (2009) 4.61
Retracted DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol (2007) 4.45
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. Cell (2010) 4.31
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR. Mol Cell (2011) 4.15
Diverse molecular functions of Hu proteins. Cell Mol Life Sci (2008) 4.09
Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors. RNA (1998) 4.05
Deadenylation is a widespread effect of miRNA regulation. RNA (2008) 3.98
Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity. J Cell Biol (1997) 3.95
Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors. RNA (2007) 3.91
Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay. EMBO J (1997) 3.91
Non-coding RNAs as regulators of embryogenesis. Nat Rev Genet (2011) 3.36
Posttranscriptional regulation of miRNAs harboring conserved terminal loops. Mol Cell (2008) 3.23
miRNAMap 2.0: genomic maps of microRNAs in metazoan genomes. Nucleic Acids Res (2007) 3.05
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell (2011) 2.99
MicroRNA biogenesis: drosha can't cut it without a partner. Curr Biol (2005) 2.85
MicroRNA precursors in motion: exportin-5 mediates their nuclear export. Trends Cell Biol (2004) 2.80
Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells. J Neurochem (2000) 2.71
Zcchc11-dependent uridylation of microRNA directs cytokine expression. Nat Cell Biol (2009) 2.63
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat Struct Mol Biol (2010) 2.30
HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs. Cancer Res (2001) 2.29
Molecular basis for interaction of let-7 microRNAs with Lin28. Cell (2011) 2.28
MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets. Mol Cell Biol (2009) 2.08
A novel proteomic screen for peptide-protein interactions. J Biol Chem (2003) 2.02
Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS. J Neurosci (2001) 1.72
MicroRNA regulation of neural stem cells and neurogenesis. J Neurosci (2010) 1.64
A SILAC-based DNA protein interaction screen that identifies candidate binding proteins to functional DNA elements. Genome Res (2008) 1.60
A splicing-independent function of SF2/ASF in microRNA processing. Mol Cell (2010) 1.55
Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3' UTR structures. RNA Biol (2011) 1.54
MicroRNA in Cancer: The Involvement of Aberrant MicroRNA Biogenesis Regulatory Pathways. Genes Cancer (2010) 1.37
RNase-assisted RNA chromatography. RNA (2010) 1.22
Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation. J Biol Chem (2011) 1.12
Musashi 2 is a regulator of the HSC compartment identified by a retroviral insertion screen and knockout mice. Blood (2011) 1.12
Musashi 2 in hematopoiesis. Curr Opin Hematol (2012) 0.93
Neonatal pancreatic cells redifferentiate into both neural and pancreatic lineages. Biochem Biophys Res Commun (2006) 0.84
A cancer fate in the hands of a samurai. Nat Med (2010) 0.80
miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev (2002) 19.24
Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein. Mol Cell Proteomics (2005) 10.67
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature (2007) 8.32
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature (2011) 8.31
Stepwise reprogramming of B cells into macrophages. Cell (2004) 7.68
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res (2004) 7.56
The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol (2007) 5.91
Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex. Cell (2008) 5.87
A model for transmission of the H3K27me3 epigenetic mark. Nat Cell Biol (2008) 5.55
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature (2006) 4.74
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev Cell (2002) 4.37
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells. Nature (2010) 4.35
Dynamic visualization of thrombopoiesis within bone marrow. Science (2007) 4.35
RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3. Cell (2007) 4.34
Cdk1 is sufficient to drive the mammalian cell cycle. Nature (2007) 4.26
Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics (2008) 3.78
Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential. Immunity (2003) 3.59
Architecture of the RNA polymerase II-TFIIF complex revealed by cross-linking and mass spectrometry. EMBO J (2010) 3.40
Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood (2010) 3.35
PU.1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cells. Proc Natl Acad Sci U S A (2008) 3.35
The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Cell (2010) 3.26
BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
Posttranscriptional regulation of miRNAs harboring conserved terminal loops. Mol Cell (2008) 3.23
The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1. Mol Cell (2008) 3.13
A novel role for shuttling SR proteins in mRNA translation. Genes Dev (2004) 3.02
Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing. Development (2004) 2.88
Structural analysis of multiprotein complexes by cross-linking, mass spectrometry, and database searching. Mol Cell Proteomics (2007) 2.78
A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation. Mol Cell (2010) 2.77
CENP-A confers a reduction in height on octameric nucleosomes. Nat Struct Mol Biol (2013) 2.64
Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors. Immunity (2006) 2.58
Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. Cell Stem Cell (2007) 2.57
Fission yeast Scm3: A CENP-A receptor required for integrity of subkinetochore chromatin. Mol Cell (2009) 2.41
Determinants of lymphoid-myeloid lineage diversification. Annu Rev Immunol (2006) 2.37
RNA structure of trinucleotide repeats associated with human neurological diseases. Nucleic Acids Res (2003) 2.34
Modular stop and go extraction tips with stacked disks for parallel and multidimensional Peptide fractionation in proteomics. J Proteome Res (2006) 2.32
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat Struct Mol Biol (2010) 2.30
Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell (2006) 2.26
Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. J Biol Chem (2001) 2.25
A novel WD repeat protein component of the methylosome binds Sm proteins. J Biol Chem (2001) 2.22
The size of the proton. Nature (2010) 2.19
Microcolumns with self-assembled particle frits for proteomics. J Chromatogr A (2002) 2.17
hnRNP A1 relocalization to the stress granules reflects a role in the stress response. Mol Cell Biol (2006) 2.13
A robust and highly efficient immune cell reprogramming system. Cell Stem Cell (2009) 2.06
Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT. Nat Struct Mol Biol (2005) 2.06
Nuclear export and retention signals in the RS domain of SR proteins. Mol Cell Biol (2002) 2.04
Geisinger's Retail Innovation Journey. Front Health Serv Manage (2015) 2.03
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus. EMBO J (2007) 1.99
Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα. J Cell Biol (2012) 1.94
eIF4A3 is a novel component of the exon junction complex. RNA (2004) 1.93
Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity. Cell (2010) 1.82
DGCR8 HITS-CLIP reveals novel functions for the Microprocessor. Nat Struct Mol Biol (2012) 1.81
Limits of life in MgCl2-containing environments: chaotropicity defines the window. Environ Microbiol (2007) 1.80
Spot overlapping in two-dimensional maps: a serious problem ignored for much too long. Proteomics (2005) 1.79
Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint. Curr Biol (2012) 1.77
Editing independent effects of ADARs on the miRNA/siRNA pathways. EMBO J (2009) 1.76
Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway. Genes Dev (2007) 1.74
Reversible phosphorylation differentially affects nuclear and cytoplasmic functions of splicing factor 2/alternative splicing factor. Proc Natl Acad Sci U S A (2005) 1.74
Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor. Nat Neurosci (2013) 1.74
CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood (2013) 1.74
Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. J Biol Chem (2001) 1.73
Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue. Blood (2004) 1.66
Splicing factors facilitate RNAi-directed silencing in fission yeast. Science (2008) 1.65
Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. Proc Natl Acad Sci U S A (2005) 1.65
Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. J Biol Chem (2002) 1.60
The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA (2003) 1.58
CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation. Proc Natl Acad Sci U S A (2011) 1.57
Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization. RNA (2009) 1.53
Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis. Blood (2006) 1.52
MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth. Nat Neurosci (2003) 1.48
Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells. Mol Cell (2012) 1.43
Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit. Dev Cell (2011) 1.43
Fibroblast-derived induced pluripotent stem cells show no common retroviral vector insertions. Stem Cells (2009) 1.41
Proton structure from the measurement of 2S-2P transition frequencies of muonic hydrogen. Science (2013) 1.39
Exploring the hidden human urinary proteome via ligand library beads. J Proteome Res (2005) 1.34
Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly. J Biol Chem (2006) 1.34
Early decisions in lymphoid development. Curr Opin Immunol (2007) 1.32
Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach. Proc Natl Acad Sci U S A (2011) 1.30
Structural diversity of triplet repeat RNAs. J Biol Chem (2010) 1.29
Unrip is a component of SMN complexes active in snRNP assembly. FEBS Lett (2005) 1.28
REST-mediated recruitment of polycomb repressor complexes in mammalian cells. PLoS Genet (2012) 1.26
A rapid and efficient protocol to purify biologically active recombinant proteins from mammalian cells. Protein Expr Purif (2005) 1.24
Quantitative cross-linking/mass spectrometry using isotope-labelled cross-linkers. J Proteomics (2013) 1.24
When less can yield more - Computational preprocessing of MS/MS spectra for peptide identification. Proteomics (2009) 1.24
RNase-assisted RNA chromatography. RNA (2010) 1.22
Proteomic analysis of human blood serum using peptide library beads. J Proteome Res (2007) 1.22
Arginine methylation of vasa protein is conserved across phyla. J Biol Chem (2010) 1.21
Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ. J Cell Biol (2010) 1.19
A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis. J Exp Med (2012) 1.18
Fibrillarin is essential for early development and required for accumulation of an intron-encoded small nucleolar RNA in the mouse. Mol Cell Biol (2003) 1.17
A genetic engineering solution to the "arginine conversion problem" in stable isotope labeling by amino acids in cell culture (SILAC). Mol Cell Proteomics (2010) 1.17
A novel SR-related protein is required for the second step of Pre-mRNA splicing. Mol Cell Biol (2005) 1.17
PU.1 is not strictly required for B cell development and its absence induces a B-2 to B-1 cell switch. J Exp Med (2005) 1.16
Unintended consequences of a quality measure for acute bronchitis. Am J Manag Care (2012) 1.16