Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

PubWeight™: 1.66^‹?› | Rank: Top 3%

🔗 View Article (PMID 26301688)

Published in Nat Med on August 24, 2015

Authors

Yun R Li¹^,2, Jin Li¹, Sihai D Zhao³, Jonathan P Bradfield¹, Frank D Mentch¹, S Melkorka Maggadottir¹^,4, Cuiping Hou¹, Debra J Abrams¹, Diana Chang⁵^,6, Feng Gao⁵, Yiran Guo⁷, Zhi Wei⁸, John J Connolly¹, Christopher J Cardinale¹, Marina Bakay¹, Joseph T Glessner¹, Dong Li¹, Charlly Kao¹, Kelly A Thomas¹, Haijun Qiu¹, Rosetta M Chiavacci¹, Cecilia E Kim¹, Fengxiang Wang¹, James Snyder¹, Marylyn D Richie⁹, Berit Flatø¹⁰, Øystein Førre¹⁰, Lee A Denson¹¹, Susan D Thompson¹², Mara L Becker¹³, Stephen L Guthery¹⁴, Anna Latiano¹⁵, Elena Perez¹⁶, Elena Resnick¹⁷, Richard K Russell¹⁸, David C Wilson¹⁹, Mark S Silverberg²⁰, Vito Annese²¹, Benedicte A Lie²², Marilynn Punaro²³, Marla C Dubinsky²⁴, Dimitri S Monos²⁵^,26, Caterina Strisciuglio²⁷, Annamaria Staiano²⁷, Erasmo Miele²⁷, Subra Kugathasan²⁸, Justine A Ellis²⁹^,30, Jane E Munro³¹^,32, Kathleen E Sullivan⁴^,26, Carol A Wise³³, Helen Chapel³⁴, Charlotte Cunningham-Rundles¹⁷, Struan F A Grant¹^,26, Jordan S Orange³⁵, Patrick M A Sleiman¹^,26, Edward M Behrens²⁶^,36, Anne M Griffiths³⁷, Jack Satsangi³⁸, Terri H Finkel³⁹, Alon Keinan⁵^,6, Eline T Luning Prak⁴⁰, Constantin Polychronakos⁴¹, Robert N Baldassano²⁶^,42, Hongzhe Li⁴⁰, Brendan J Keating¹^,26, Hakon Hakonarson¹^,26^,43

Author Affiliations

1: The Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
2: Medical Scientist Training Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
3: Department of Biostatistics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
4: Division of Allergy and Immunology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
5: Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA.
6: Program in Computational Biology and Medicine, Cornell University, Ithaca, New York, USA.
7: Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA;
8: Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, USA.
9: Department of Biochemistry and Molecular Biology, Eberly College of Science, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
10: Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
11: Division of Gastroenterology, The Center for Inflammatory Bowel Disease, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
12: Divison of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
13: Division of Rheumatology, Children's Mercy Hospitals and Clinics, Kansas City, Missouri, USA.
14: Department of Pediatrics, University of Utah School of Medicine and Primary Children's Medical Center, Salt Lake City, Utah, USA.
15: Division of Gastroenterology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
16: Division of Pediatric Allergy and Immunology, University of Miami Miller School of Medicine, Miami, Florida, USA.
17: Institute of Immunology and Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.
18: Department of Paediatric Gastroenterology, Yorkhill Hospital for Sick Children, Glasgow, Scotland, UK.
19: Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, University of Edinburgh, Ediburgh, UK.
20: Mount Sinai Hospital IBD Centre, University of Toronto, Toronto, Ontario, Canada.
21: Unit of Gastroenterology, Department of Medical and Surgical Specialties, Careggi University Hospital, Florence, Italy.
22: Department of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
23: Department of Rheumatology, Texas Scottish Rite Hospital for Children, Dallas, Texas, USA.
24: Department of Pediatrics, Pediatric IBD Center, Cedars Sinai Medical Center, Los Angeles, California, USA.
25: Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
26: Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
27: Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy.
28: Department of Pediatrics, Emory University School of Medicine and Children's Health Care of Atlanta, Atlanta, Georgia, USA.
29: Genes, Environment and Complex Disease, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
30: Department of Pediatrics, University of Melbourne, Parkville, Victoria, Australia.
31: Pediatric Rheumatology Unit, Royal Children's Hospital, Parkville, Victoria, Australia.
32: Arthritis and Rheumatology Research, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
33: Sarah M. and Charles E. Seay Center for Musculoskeletal Research, Texas Scottish Rite Hospital for Children, Dallas, Texas, USA.
34: Department of Clinical Immunology, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
35: Section of Immunology, Allergy, and Rheumatology, Department of Pediatric Medicine, Texas Children's Hospital, Houston, Texas, USA.
36: Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
37: The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
38: Gastrointestinal Unit, Division of Medical Sciences, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, UK.
39: Department of Pediatrics, Nemours Children's Hospital, Orlando, Florida, USA.
40: Department of Pathology and Lab Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
41: Departments of Pediatrics and Human Genetics, McGill University Health Centre Research Institute, Montréal, Québec, Canada.
42: Division of Gastroenterology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
43: Division of Pulmonary Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.