U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing.

PubWeight™: 8.85‹?› | Rank: Top 0.1%

🔗 View Article (PMID 2996775)

Published in Cell on October 01, 1985

Authors

D L Black, B Chabot, J A Steitz

Articles citing this

(truncated to the top 100)

Multiple alignment using simulated annealing: branch point definition in human mRNA splicing. Nucleic Acids Res (1992) 12.08

Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol Cell Biol (1990) 8.17

Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc Natl Acad Sci U S A (1989) 5.11

Splicing signals in Drosophila: intron size, information content, and consensus sequences. Nucleic Acids Res (1992) 4.93

An ordered pathway of snRNP binding during mammalian pre-mRNA splicing complex assembly. EMBO J (1987) 4.52

Cloning of the human cDNA for the U1 RNA-associated 70K protein. EMBO J (1986) 4.43

RNA binding specificity of hnRNP proteins: a subset bind to the 3' end of introns. EMBO J (1988) 4.26

The yeast homologue of U3 snRNA. EMBO J (1987) 3.74

In vivo disruption of Xenopus U3 snRNA affects ribosomal RNA processing. EMBO J (1990) 3.73

Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles. Mol Cell Biol (1988) 3.56

Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs. EMBO J (1987) 3.50

cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins. EMBO J (1987) 3.47

Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein. Proc Natl Acad Sci U S A (1988) 3.38

Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome. EMBO J (1986) 3.35

U6 small nuclear RNA is transcribed by RNA polymerase III. Proc Natl Acad Sci U S A (1986) 3.14

Different effects of intron nucleotide composition and secondary structure on pre-mRNA splicing in monocot and dicot plants. EMBO J (1991) 3.12

hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. Mol Cell Biol (1999) 3.06

The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site. Proc Natl Acad Sci U S A (1992) 3.04

Multiple interactions between the splicing substrate and small nuclear ribonucleoproteins in spliceosomes. Mol Cell Biol (1987) 3.00

Pre-mRNA splicing by complementation with purified human U1, U2, U4/U6 and U5 snRNPs. Nucleic Acids Res (1988) 2.86

Localization of Epstein-Barr virus-encoded small RNAs by in situ hybridization. Proc Natl Acad Sci U S A (1986) 2.84

U5 small nuclear ribonucleoprotein: RNA structure analysis and ATP-dependent interaction with U4/U6. Mol Cell Biol (1989) 2.82

Purification of the individual snRNPs U1, U2, U5 and U4/U6 from HeLa cells and characterization of their protein constituents. EMBO J (1986) 2.79

Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B" antigen. Proc Natl Acad Sci U S A (1987) 2.75

Early commitment of yeast pre-mRNA to the spliceosome pathway. Mol Cell Biol (1988) 2.64

Protein composition of mammalian spliceosomes assembled in vitro. Proc Natl Acad Sci U S A (1990) 2.58

Monocot and dicot pre-mRNAs are processed with different efficiencies in transgenic tobacco. EMBO J (1986) 2.53

Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns. PLoS Biol (2006) 2.51

Plant intron sequences: evidence for distinct groups of introns. Nucleic Acids Res (1988) 2.42

PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle. Mol Cell Biol (1989) 2.41

Factors influencing alternative splice site utilization in vivo. Mol Cell Biol (1987) 2.39

Nucleotide sequence of a bean (Phaseolus vulgaris) U1 small nuclear RNA gene: implications for plant pre-mRNA splicing. Proc Natl Acad Sci U S A (1987) 2.36

Small nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditions. Mol Cell Biol (1993) 2.36

Ribonucleoprotein complex formation during pre-mRNA splicing in vitro. Mol Cell Biol (1986) 2.33

Genetic complementation in the Xenopus oocyte: co-expression of sea urchin histone and U7 RNAs restores 3' processing of H3 pre-mRNA in the oocyte. EMBO J (1986) 2.29

Antibodies to hnRNP core proteins inhibit in vitro splicing of human beta-globin pre-mRNA. Nucleic Acids Res (1986) 2.28

Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc. Proc Natl Acad Sci U S A (1988) 2.26

Nuclear pre-mRNA introns: analysis and comparison of intron sequences from Tetrahymena thermophila and other eukaryotes. Nucleic Acids Res (1990) 2.25

Pre-mRNA splicing and the nuclear matrix. Mol Cell Biol (1987) 2.22

Nucleotide sequence determination and secondary structure of Xenopus U3 snRNA. Nucleic Acids Res (1988) 2.20

Spontaneous splicing mutations at the dihydrofolate reductase locus in Chinese hamster ovary cells. Mol Cell Biol (1986) 2.19

Deletion of a yeast small nuclear RNA gene impairs growth. EMBO J (1985) 2.17

Small nuclear RNAs from Saccharomyces cerevisiae: unexpected diversity in abundance, size, and molecular complexity. Proc Natl Acad Sci U S A (1986) 2.12

Unusual branch point selection in processing of human growth hormone pre-mRNA. Mol Cell Biol (1988) 2.12

Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. J Cell Biol (1994) 2.12

Human U2 small nuclear RNA genes contain an upstream enhancer. EMBO J (1986) 2.10

Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function. Mol Cell Biol (1991) 2.06

Polypyrimidine tract binding protein blocks the 5' splice site-dependent assembly of U2AF and the prespliceosomal E complex. Mol Cell (2005) 2.05

Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly. Mol Cell Biol (1994) 2.03

An intron element modulating 5' splice site selection in the hnRNP A1 pre-mRNA interacts with hnRNP A1. Mol Cell Biol (1997) 2.00

Both conserved signals on mammalian histone pre-mRNAs associate with small nuclear ribonucleoproteins during 3' end formation in vitro. Mol Cell Biol (1987) 1.98

Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA. J Cell Biol (1986) 1.98

Immunization of mice with purified U1 small nuclear ribonucleoprotein (RNP) induces a pattern of antibody specificities characteristic of the anti-Sm and anti-RNP autoimmune response of patients with lupus erythematosus, as measured by monoclonal antibodies. Proc Natl Acad Sci U S A (1986) 1.96

Domains of U4 and U6 snRNAs required for snRNP assembly and splicing complementation in Xenopus oocytes. EMBO J (1990) 1.96

Monospecific antibodies reveal details of U2 snRNP structure and interaction between U1 and U2 snRNPs. EMBO J (1986) 1.96

Structure of U2 snRNA genes of Arabidopsis thaliana and their expression in electroporated plant protoplasts. EMBO J (1988) 1.95

PRP4 (RNA4) from Saccharomyces cerevisiae: its gene product is associated with the U4/U6 small nuclear ribonucleoprotein particle. Mol Cell Biol (1989) 1.95

The U1 RNA-binding site of the U1 small nuclear ribonucleoprotein (snRNP)-associated A protein suggests a similarity with U2 snRNPs. Mol Cell Biol (1989) 1.87

Structure and expression of the Drosophila melanogaster gene for the U1 small nuclear ribonucleoprotein particle 70K protein. Mol Cell Biol (1990) 1.85

U1 small nuclear ribonucleoproteins are required early during spliceosome assembly. Mol Cell Biol (1987) 1.83

Nuclear pre-mRNA splicing in the fission yeast Schizosaccharomyces pombe strictly requires an intron-contained, conserved sequence element. EMBO J (1987) 1.82

Nucleotide substitutions within the cardiac troponin T alternative exon disrupt pre-mRNA alternative splicing. Nucleic Acids Res (1989) 1.81

Accurate in vitro splicing of two pre-mRNA plant introns in a HeLa cell nuclear extract. EMBO J (1986) 1.80

Tissue-specific expression and cDNA cloning of small nuclear ribonucleoprotein-associated polypeptide N. Proc Natl Acad Sci U S A (1988) 1.78

Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts. Nucleic Acids Res (1991) 1.78

Heat shock but not other stress inducers leads to the disruption of a sub-set of snRNPs and inhibition of in vitro splicing in HeLa cells. EMBO J (1988) 1.78

The spliceosome assembly pathway in mammalian extracts. Mol Cell Biol (1992) 1.78

The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome. Mol Cell Biol (1993) 1.77

U1 snRNP-ASF/SF2 interaction and 5' splice site recognition: characterization of required elements. Nucleic Acids Res (1995) 1.77

A nuclear cap binding protein from HeLa cells. Nucleic Acids Res (1990) 1.77

An intronic splicing enhancer binds U1 snRNPs to enhance splicing and select 5' splice sites. Mol Cell Biol (2000) 1.75

The low-abundance U11 and U12 small nuclear ribonucleoproteins (snRNPs) interact to form a two-snRNP complex. Mol Cell Biol (1992) 1.74

Formation of mRNA 3' termini: stability and dissociation of a complex involving the AAUAAA sequence. EMBO J (1987) 1.73

Mapping U2 snRNP--pre-mRNA interactions using biotinylated oligonucleotides made of 2'-OMe RNA. EMBO J (1989) 1.73

The length of the downstream exon and the substitution of specific sequences affect pre-mRNA splicing in vitro. Mol Cell Biol (1988) 1.69

Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs. Nucleic Acids Res (1990) 1.68

A specific 31-nucleotide domain of U1 RNA directly interacts with the 70K small nuclear ribonucleoprotein component. Mol Cell Biol (1989) 1.68

Identification of an essential Schizosaccharomyces pombe RNA homologous to the 7SL component of signal recognition particle. Mol Cell Biol (1988) 1.66

Electron microscopy of small nuclear ribonucleoprotein (snRNP) particles U2 and U5: evidence for a common structure-determining principle in the major U snRNP family. Proc Natl Acad Sci U S A (1990) 1.65

Requirements for accurate and efficient mRNA 3' end cleavage and polyadenylation of a simian virus 40 early pre-RNA in vitro. Mol Cell Biol (1987) 1.65

Pre-mRNA splicing mutants of Schizosaccharomyces pombe. EMBO J (1989) 1.63

The sequence of U3 from Schizosaccharomyces pombe suggests structural divergence of this snRNA between metazoans and unicellular eukaryotes. Nucleic Acids Res (1988) 1.61

Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing. Nucleic Acids Res (1995) 1.61

Multiple domains of U1 snRNA, including U1 specific protein binding sites, are required for splicing. EMBO J (1990) 1.60

Mechanism for cryptic splice site activation during pre-mRNA splicing. Proc Natl Acad Sci U S A (1990) 1.60

Cotranscriptional recruitment of the U1 snRNP to intron-containing genes in yeast. Mol Cell Biol (2003) 1.60

Polypyrimidine tract sequences direct selection of alternative branch sites and influence protein binding. Nucleic Acids Res (1994) 1.58

The U2 RNA analogue of Trypanosoma brucei gambiense: implications for a splicing mechanism in trypanosomes. Nucleic Acids Res (1986) 1.57

U1 small nuclear ribonucleoprotein particle-specific proteins interact with the first and second stem-loops of U1 RNA, with the A protein binding directly to the RNA independently of the 70K and Sm proteins. Mol Cell Biol (1989) 1.56

Purification of a protein required for the splicing of pre-mRNA and its separation from the lariat debranching enzyme. EMBO J (1985) 1.56

Fractionation and characterization of a yeast mRNA splicing extract. Proc Natl Acad Sci U S A (1986) 1.56

Structural and functional analysis of chicken U4 small nuclear RNA genes. Mol Cell Biol (1986) 1.54

Plant small nuclear RNAs. II. U6 RNA and a 4.5SI-like RNA are present in plant nuclei. Nucleic Acids Res (1987) 1.54

Specific accessory sequences in Saccharomyces cerevisiae introns control assembly of pre-mRNAs into spliceosomes. EMBO J (1987) 1.53

Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17. Mol Cell Biol (2000) 1.53

Formation of the 3' end on U snRNAs requires at least three sequence elements. EMBO J (1986) 1.52

The 216-nucleotide intron of the E1A pre-mRNA contains a hairpin structure that permits utilization of unusually distant branch acceptors. Mol Cell Biol (1989) 1.48

Plant small nuclear RNAs. III. The complete primary and secondary structure of broad bean U2 RNA: phylogenetic and functional implications. Nucleic Acids Res (1987) 1.47

Transcription of the intergenic regions of the tubulin gene cluster of Trypanosoma brucei: evidence for a polycistronic transcription unit in a eukaryote. Nucleic Acids Res (1987) 1.47

Evidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of prespliceosomes. Proc Natl Acad Sci U S A (1993) 1.46

Articles by these authors

Are snRNPs involved in splicing? Nature (1980) 15.47

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1979) 14.61

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease. Proc Natl Acad Sci U S A (1981) 10.72

How ribosomes select initiator regions in mRNA: base pair formation between the 3' terminus of 16S rRNA and the mRNA during initiation of protein synthesis in Escherichia coli. Proc Natl Acad Sci U S A (1975) 10.60

The U1 small nuclear RNA-protein complex selectively binds a 5' splice site in vitro. Cell (1983) 9.00

Conservation of the primary structure at the 3' end of 18S rRNA from eucaryotic cells. Cell (1978) 8.98

Polypeptide chain initiation: nucleotide sequences of the three ribosomal binding sites in bacteriophage R17 RNA. Nature (1969) 8.64

Identification of a sex-factor-affinity site in E. coli as gamma delta. Cold Spring Harb Symp Quant Biol (1981) 8.26

HuR and mRNA stability. Cell Mol Life Sci (2001) 8.06

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J (1998) 7.62

Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1981) 7.43

A general two-metal-ion mechanism for catalytic RNA. Proc Natl Acad Sci U S A (1993) 7.09

Two novel classes of small ribonucleoproteins detected by antibodies associated with lupus erythematosus. Science (1981) 6.34

U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus. EMBO J (1989) 6.19

Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly. Mol Cell Biol (1987) 5.63

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon. Cell (2000) 5.54

The U3 small nucleolar ribonucleoprotein functions in the first step of preribosomal RNA processing. Cell (1990) 5.39

A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding. Genes Dev (1993) 5.10

Complementary sequences 1700 nucleotides apart form a ribonuclease III cleavage site in Escherichia coli ribosomal precursor RNA. Proc Natl Acad Sci U S A (1978) 4.90

A mammalian gene with introns instead of exons generating stable RNA products. Nature (1996) 4.87

The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies. J Biol Chem (1984) 4.68

Sno storm in the nucleolus: new roles for myriad small RNPs. Cell (1997) 4.60

The 3' splice site of pre-messenger RNA is recognized by a small nuclear ribonucleoprotein. Science (1985) 4.56

A protein associated with small nuclear ribonucleoprotein particles recognizes the 3' splice site of premessenger RNA. Cell (1986) 4.44

Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein. Cell (1983) 4.42

Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells. Mol Cell Biol (1981) 4.41

Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII. Mol Cell Biol (1981) 4.39

Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1. Science (2001) 4.20

The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli. Cell (1980) 4.19

Sequence of the 16 S-23 s spacer region in two ribosomal RNA operons of Escherichia coli. J Biol Chem (1979) 4.19

HuR binding to cytoplasmic mRNA is perturbed by heat shock. Proc Natl Acad Sci U S A (2000) 4.14

HNS, a nuclear-cytoplasmic shuttling sequence in HuR. Proc Natl Acad Sci U S A (1998) 4.14

Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein. Mol Cell Biol (2000) 4.12

Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing. Science (1992) 3.94

Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay. EMBO J (1997) 3.91

Guided tours: from precursor snoRNA to functional snoRNP. Curr Opin Cell Biol (1999) 3.88

A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev (1997) 3.88

Four novel U RNAs are encoded by a herpesvirus. Cell (1988) 3.86

The U5 and U6 small nuclear RNAs as active site components of the spliceosome. Science (1993) 3.83

Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La lupus antibodies. Cell (1982) 3.76

A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences. Proc Natl Acad Sci U S A (1981) 3.68

Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing. EMBO J (1998) 3.66

Sequence of U1 RNA from Drosophila melanogaster: implications for U1 secondary structure and possible involvement in splicing. Nucleic Acids Res (1981) 3.65

Isolation of small nuclear ribonucleoproteins containing U1, U2, U4, U5, and U6 RNAs. J Biol Chem (1983) 3.65

Pre-mRNA splicing in vitro requires intact U4/U6 small nuclear ribonucleoprotein. Cell (1986) 3.62

U4 and U6 RNAs coexist in a single small nuclear ribonucleoprotein particle. Nucleic Acids Res (1984) 3.61

Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing. Genes Dev (1992) 3.58

A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro. Cell (1996) 3.55

The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs. Proc Natl Acad Sci U S A (1984) 3.51

Structural analysis of the human U3 ribonucleoprotein particle reveal a conserved sequence available for base pairing with pre-rRNA. Mol Cell Biol (1987) 3.46

Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns. Science (1996) 3.44

Alternative RNA splicing in the nervous system. Prog Neurobiol (2001) 3.38

Tandem promoters direct E. coli ribosomal RNA synthesis. Cell (1979) 3.36

RNA splicing. Alive with DEAD proteins. Nature (1991) 3.35

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice. Genes Dev (1989) 3.29

A new method for detecting sites of 2'-O-methylation in RNA molecules. RNA (1997) 3.17

Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA. Mol Cell (2001) 3.14

Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III. EMBO J (1989) 3.13

Classification of gas5 as a multi-small-nucleolar-RNA (snoRNA) host gene and a member of the 5'-terminal oligopyrimidine gene family reveals common features of snoRNA host genes. Mol Cell Biol (1998) 3.08

hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. Mol Cell Biol (1999) 3.06

Identification of the human U7 snRNP as one of several factors involved in the 3' end maturation of histone premessenger RNA's. Science (1987) 3.04

Multiple interactions between the splicing substrate and small nuclear ribonucleoproteins in spliceosomes. Mol Cell Biol (1987) 3.00

Disruption of U8 nucleolar snRNA inhibits 5.8S and 28S rRNA processing in the Xenopus oocyte. Cell (1993) 2.94

The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream. Mol Cell Biol (1997) 2.93

The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo. Proc Natl Acad Sci U S A (1994) 2.92

Delineation of mRNA export pathways by the use of cell-permeable peptides. Science (2001) 2.87

Trans splicing involves a novel form of small nuclear ribonucleoprotein particles. Nature (1988) 2.87

The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event. Genes Dev (1995) 2.87

Localization of Epstein-Barr virus-encoded small RNAs by in situ hybridization. Proc Natl Acad Sci U S A (1986) 2.84

Autoantibodies to the U2 small nuclear ribonucleoprotein in a patient with scleroderma-polymyositis overlap syndrome. J Biol Chem (1984) 2.81

Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders. J Biol Chem (1986) 2.79

Protein ligands to HuR modulate its interaction with target mRNAs in vivo. J Cell Biol (2000) 2.69

A complex intronic splicing enhancer from the c-src pre-mRNA activates inclusion of a heterologous exon. Mol Cell Biol (1997) 2.66

Modification of U6 spliceosomal RNA is guided by other small RNAs. Mol Cell (1998) 2.62

SR proteins can compensate for the loss of U1 snRNP functions in vitro. Genes Dev (1994) 2.55

Snurps and scyrps. Cell (1981) 2.54

Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase. Nat Genet (1998) 2.53

The RNA binding protein La influences both the accuracy and the efficiency of RNA polymerase III transcription in vitro. EMBO J (1989) 2.52

A small nuclear ribonucleoprotein associates with the AAUAAA polyadenylation signal in vitro. Cell (1986) 2.51

The 3' terminus of 16S rRNA: secondary structure and interaction with ribosomal protein S1. Nucleic Acids Res (1979) 2.51

Discriminatory ribosome rebinding of isolated regions of protein synthesis initiation from the ribonucleic acid of bacteriophage R17. Proc Natl Acad Sci U S A (1973) 2.48

Transposition of the Escherichia coli insertion element gamma generates a five-base-pair repeat. Proc Natl Acad Sci U S A (1979) 2.47

A small nucleolar RNA is processed from an intron of the human gene encoding ribosomal protein S3. Genes Dev (1993) 2.44

Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genome. Cell (1983) 2.40

Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing. Mol Cell (2000) 2.39

An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs. EMBO J (1991) 2.38

Structural analyses of EBER1 and EBER2 ribonucleoprotein particles present in Epstein-Barr virus-infected cells. J Virol (1988) 2.37

Modulation of exon skipping by high-affinity hnRNP A1-binding sites and by intron elements that repress splice site utilization. EMBO J (1999) 2.34

Requirement for intron-encoded U22 small nucleolar RNA in 18S ribosomal RNA maturation. Science (1994) 2.31

Site-specific interaction of Qbeta host factor and ribosomal protein S1 with Qbeta and R17 bacteriophage RNAs. J Biol Chem (1976) 2.29

Multiple processing-defective mutations in a mammalian histone pre-mRNA are suppressed by compensatory changes in U7 RNA both in vivo and in vitro. Genes Dev (1991) 2.28

Direct physical evidence for secondary structure in an isolated fragment of R17 bacteriophage mRNA. Nature (1974) 2.28

Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc. Proc Natl Acad Sci U S A (1988) 2.26

Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge. Trends Biochem Sci (1997) 2.19

A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus. Proc Natl Acad Sci U S A (1996) 2.18

A CaMK IV responsive RNA element mediates depolarization-induced alternative splicing of ion channels. Nature (2001) 2.15