Published in EMBO J on August 01, 1987
Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol Cell Biol (1990) 8.17
Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc Natl Acad Sci U S A (1989) 5.11
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A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5' cleavage site. EMBO J (1988) 4.34
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PRP18, a protein required for the second reaction in pre-mRNA splicing. Mol Cell Biol (1990) 1.48
Evidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of prespliceosomes. Proc Natl Acad Sci U S A (1993) 1.46
Branch point selection in alternative splicing of tropomyosin pre-mRNAs. Nucleic Acids Res (1989) 1.43
Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation. Nucleic Acids Res (2010) 1.43
Genetic depletion indicates a late role for U5 snRNP during in vitro spliceosome assembly. Nucleic Acids Res (1991) 1.40
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Sequence-specific affinity selection of mammalian splicing complexes. Nucleic Acids Res (1990) 1.22
The biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP. Nucleic Acids Res (1993) 1.21
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Combinatorial splicing of exon pairs by two-site binding of U1 small nuclear ribonucleoprotein particle. Mol Cell Biol (1991) 1.19
Prp31p promotes the association of the U4/U6 x U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae. Mol Cell Biol (1997) 1.19
Unusual branch point selection involved in splicing of the alternatively processed Calcitonin/CGRP-I pre-mRNA. Nucleic Acids Res (1988) 1.18
Mammalian U6 small nuclear RNA undergoes 3' end modifications within the spliceosome. Mol Cell Biol (1993) 1.17
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The Saccharomyces cerevisiae PRP21 gene product is an integral component of the prespliceosome. Proc Natl Acad Sci U S A (1993) 1.15
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Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing. Nucleic Acids Res (1992) 1.12
The phylogenetically invariant ACAGAGA and AGC sequences of U6 small nuclear RNA are more tolerant of mutation in human cells than in Saccharomyces cerevisiae. Mol Cell Biol (1993) 1.12
In vitro splicing of mRNA precursors: 5' cleavage site can be predicted from the interaction between the 5' splice region and the 5' terminus of U1 snRNA. Nucleic Acids Res (1988) 1.11
Splice site choice in a complex transcription unit containing multiple inefficient polyadenylation signals. Mol Cell Biol (1991) 1.10
A yeast splicing factor is localized in discrete subnuclear domains. EMBO J (1992) 1.08
Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiation in situ. Nucleic Acids Res (1988) 1.08
Uncoupling two functions of the U1 small nuclear ribonucleoprotein particle during in vitro splicing. Mol Cell Biol (1993) 1.07
Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain. RNA (2006) 1.06
The pre-mRNA 5' cap determines whether U6 small nuclear RNA succeeds U1 small nuclear ribonucleoprotein particle at 5' splice sites. Mol Cell Biol (1998) 1.05
Rds3p is required for stable U2 snRNP recruitment to the splicing apparatus. Mol Cell Biol (2003) 1.04
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An ATP-independent U2 small nuclear ribonucleoprotein particle/precursor mRNA complex requires both splice sites and the polypyrimidine tract. Proc Natl Acad Sci U S A (1992) 1.03
Evidence from complementation assays in vitro that U5 snRNP is required for both steps of mRNA splicing. EMBO J (1989) 1.03
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Prespliceosomal assembly on microinjected precursor mRNA takes place in nuclear speckles. Mol Biol Cell (2001) 0.98
Multiple functional domains of human U2 small nuclear RNA: strengthening conserved stem I can block splicing. Mol Cell Biol (1992) 0.97
Three novel functional variants of human U5 small nuclear RNA. Mol Cell Biol (1992) 0.96
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The dependence of splicing efficiency on the length of 3' exon. Nucleic Acids Res (1988) 0.95
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U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing. Cell (1985) 8.85
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