Published in Mol Cell Biol on April 01, 1986
Polylactosaminoglycan modification of a small integral membrane glycoprotein, influenza B virus NB. Mol Cell Biol (1988) 1.18
The avian erythroblastosis virus erbA oncogene encodes a DNA-binding protein exhibiting distinct nuclear and cytoplasmic subcellular localizations. J Virol (1988) 1.13
Transposition of domains between the M2 and HN viral membrane proteins results in polypeptides which can adopt more than one membrane orientation. J Cell Biol (1989) 1.00
Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB. Proc Natl Acad Sci U S A (1988) 0.98
The amino-terminal 14 amino acids of v-src can functionally replace the extracellular and transmembrane domains of v-erbB. Mol Cell Biol (1991) 0.88
Will kinase inhibitors make it as glioblastoma drugs? Curr Top Microbiol Immunol (2012) 0.87
Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene. Proc Natl Acad Sci U S A (1986) 0.87
Transformation of chicken embryo fibroblasts by direct DNA transfection of single oncogenes: comparative analyses of src, erbB, myc, and ras. J Virol (1990) 0.84
Isolation of new oncogenic forms of the murine c-fms gene. J Virol (1995) 0.75
Prediction of protein antigenic determinants from amino acid sequences. Proc Natl Acad Sci U S A (1981) 32.98
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature (1984) 17.70
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature (1984) 14.21
Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc Natl Acad Sci U S A (1978) 5.91
Journey to the center of the cell: role of the receptosome. Science (1981) 4.07
Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbB protein. Cell (1985) 4.02
Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus. Cell (1982) 3.53
Immunocytochemical visualization of coated pits and vesicles in human fibroblasts: relation to low density lipoprotein receptor distribution. Cell (1978) 3.17
The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence. Cell (1984) 3.14
Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes. Cell (1983) 3.03
Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies. J Biol Chem (1983) 2.94
Isolation of monoclonal antibodies specific for products of avian oncogene myb. Mol Cell Biol (1984) 2.50
Identification and characterization of the avian erythroblastosis virus erbB gene product as a membrane glycoprotein. Cell (1983) 2.44
Evidence for the multiple oncogenic potential of cloned leukemia virus: in vitro and in vitro studies with avian erythroblastosis virus. Virology (1976) 2.28
Rat liver asialoglycoprotein receptor lacks a cleavable NH2-terminal signal sequence. Proc Natl Acad Sci U S A (1984) 2.15
Antibodies against synthetic peptides as a tool for functional analysis of the transforming protein pp60src. Cell (1983) 1.91
The product of the avian erythroblastosis virus erbB locus is a glycoprotein. Cell (1983) 1.62
Temperature-sensitive mutants of avian erythroblastosis virus: surface expression of the erbB product correlates with transformation. Cell (1984) 1.43
Identification of a form of the avian erythroblastosis virus erb-B gene product at the cell surface. Nature (1984) 1.40
Site-specific mutagenesis of avian erythroblastosis virus: v-erb-A is not required for transformation of fibroblasts. Virology (1983) 1.40
Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin. Proc Natl Acad Sci U S A (1980) 1.36
Properties of a monoclonal antibody to epidermal growth factor receptor with implications for the mechanism of action of EGF. EMBO J (1984) 1.34
The occurrence in proteins of the tripeptides Asn-X-Ser and Asn-X-Thr and of bound carbohydrate. Biochem Biophys Res Commun (1970) 1.25
Subcellular localization of the v-erb-B protein, the product of a transforming gene of avian erythroblastosis virus. Virology (1984) 1.20
Endogenous protein phosphorylation and dephosphorylation. Adv Cyclic Nucleotide Res (1979) 1.12
Phosphorylation of the erbB gene product from an avian erythroblastosis virus-transformed chick fibroblast cell line. J Biol Chem (1985) 0.94
Effects of inhibitors of glycoprotein processing on the synthesis and biological activity of the erb B oncogene. EMBO J (1985) 0.93
Power and the environment. Nature (1970) 0.87
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet (1996) 26.06
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol Cell Biol (1985) 25.52
Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell (1978) 13.33
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein. Cell (1978) 11.17
Correct integration of retroviral DNA in vitro. Cell (1987) 10.73
Cellular oncogenes and retroviruses. Annu Rev Biochem (1983) 10.65
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol (2000) 9.87
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (1976) 9.81
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science (1984) 9.64
Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas. Nature (1982) 9.12
A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev (1989) 8.80
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell (1997) 8.72
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (1983) 8.18
Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. Proc Natl Acad Sci U S A (1989) 8.13
Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell (1999) 8.03
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res (1995) 7.95
The molecular genetics of cancer. Science (1987) 7.64
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). Proc Natl Acad Sci U S A (1979) 7.55
Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell (1978) 7.46
Molecular cloning and characterization of avian sarcoma virus circular DNA molecules. J Virol (1980) 7.37
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proc Natl Acad Sci U S A (1983) 7.01
Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the tumor state. Cell (1981) 6.98
Virus-specific ribonucleic acid in cells producing rous sarcoma virus: detection and characterization. J Virol (1972) 6.38
Standardized and simplified nomenclature for proteins common to all retroviruses. J Virol (1988) 6.31
Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: the architecture of a transduced oncogene. Cell (1982) 6.19
Transcripts from the cellular homologs of retroviral oncogenes: distribution among chicken tissues. Mol Cell Biol (1982) 5.70
Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol Cell Biol (1987) 5.67
Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature (1992) 5.50
Retroviruses. Annu Rev Biochem (1978) 5.41
The size and genetic composition of virus-specific RNAs in the cytoplasm of cells producing avian sarcoma-leukosis viruses. Cell (1977) 5.23
Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product. Nature (1980) 5.22
Viral oncogenes. Cell (1985) 5.20
Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev (1998) 5.14
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. J Mol Biol (1976) 5.07
The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane. Proc Natl Acad Sci U S A (1980) 4.99
Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J (1997) 4.99
The MYC protein activates transcription of the alpha-prothymosin gene. EMBO J (1991) 4.96
Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src). Proc Natl Acad Sci U S A (1981) 4.69
Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature (1989) 4.65
The low molecular weight RNAs of Rous sarcoma virus. I. The 4 S RNA. Virology (1970) 4.64
The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature (2006) 4.57
Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA. Cell (1983) 4.53
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proc Natl Acad Sci U S A (1978) 4.47
c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature (2001) 4.46
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture. Nature (1985) 4.31
Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts. Proc Natl Acad Sci U S A (1973) 4.19
A joint produce of the genes gag and pol of avian sarcoma virus: a possible precursor of reverse transcriptase. Cell (1977) 4.18
Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell (1993) 4.10
Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA. Cell (1977) 4.06
Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src). Proc Natl Acad Sci U S A (1981) 4.04
Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells. J Mol Biol (1978) 4.04
The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine. J Biol Chem (1980) 3.95
Transcription of DNA from the 70S RNA of Rous sarcoma virus. I. Identification of a specific 4S RNA which serves as primer. J Virol (1974) 3.90
A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Cell (1990) 3.87
Identification of nuclear proteins encoded by viral and cellular myc oncogenes. Nature (1984) 3.86
Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements. Proc Natl Acad Sci U S A (1981) 3.82
Computer-based screening system for patients at risk of hypothyroidism. Lancet (1969) 3.70
DNA and RNA from uninfected vertebrate cells contain nucleotide sequences related to the putative transforming gene of avian myelocytomatosis virus. J Virol (1979) 3.68
Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus. Nature (1975) 3.63
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J (1994) 3.58
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells. Nature (1983) 3.56
Induction of apoptosis by the Bcl-2 homologue Bak. Nature (1995) 3.56
Purification and characterization of the deoxyribonucleic acid polymerase associated with Rous sarcoma virus. Biochemistry (1972) 3.53
Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus. Cell (1982) 3.53
Interaction between the origin recognition complex and the replication licensing system in Xenopus. Cell (1996) 3.45
Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature (1992) 3.43
Daily requirement of oxygen to reverse pulmonary hypertension in patients with chronic bronchitis. Br Med J (1972) 3.43
Corrections to the nucleotide sequence of the src gene of Rous sarcoma virus. Nature (1983) 3.42
Transduction of a cellular oncogene: the genesis of Rous sarcoma virus. Proc Natl Acad Sci U S A (1983) 3.41
Production of mouse mammary tumor virus by cultured cells in the absence and presence of hormones: assay by molecular hybridization. Virology (1975) 3.40
HFE gene knockout produces mouse model of hereditary hemochromatosis. Proc Natl Acad Sci U S A (1998) 3.35
A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein. Proc Natl Acad Sci U S A (1981) 3.32
RNA-directed DNA polymerase of Rous sarcoma virus: initiation of synthesis with 70 S viral RNA as template. J Mol Biol (1973) 3.32
The protein encoded by the human proto-oncogene c-myc. Proc Natl Acad Sci U S A (1984) 3.31
Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA. Proc Natl Acad Sci U S A (1977) 3.31
Detection of avian tumor virus-specific nucleotide sequences in avian cell DNAs (reassociation kinetics-RNA tumor viruses-gas antigen-Rous sarcoma virus, chick cells). Proc Natl Acad Sci U S A (1972) 3.28
Transient excess of MYC activity can elicit genomic instability and tumorigenesis. Proc Natl Acad Sci U S A (1999) 3.24
The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant. Mol Cell Biol (1988) 3.24
The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding. Proc Natl Acad Sci U S A (1998) 3.23
New method for oxygen therapy in the home using an oxygen concentrator. Br Med J (1973) 3.22
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb. Cell (1989) 3.21
Appearance of virus-specific DNA in mammalian cells following transformation by Rous sarcoma virus. J Mol Biol (1973) 3.21
The product of the retroviral transforming gene v-myb is a truncated version of the protein encoded by the cellular oncogene c-myb. Cell (1983) 3.21
A PMLRARalpha transgene initiates murine acute promyelocytic leukemia. Proc Natl Acad Sci U S A (1997) 3.20
Characterization of the low-molecular-weight RNAs associated with the 70S RNA of Rous sarcoma virus. J Virol (1973) 3.19
Proposal for naming host cell-derived inserts in retrovirus genomes. J Virol (1981) 3.18
The nucleotide sequence of an untranslated but conserved domain at the 3' end of the avian sarcoma virus genome. Nucleic Acids Res (1980) 3.16
Medical audits. J R Coll Physicians Lond (1980) 3.15
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase. Mol Cell Biol (1993) 3.13
Restricted expression of EBV latent genes and T-lymphocyte-detected membrane antigen in Burkitt's lymphoma cells. EMBO J (1986) 3.07
Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2. Cell (1997) 3.06
Reversal of pulmonary hypertension by prolonged oxygen administration to patients with chronic bronchitis. Circ Res (1968) 3.06
Expression of v-src and chicken c-src in rat cells demonstrates qualitative differences between pp60v-src and pp60c-src. Cell (1984) 3.06
Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J Cell Biol (1997) 3.03
Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells. J Virol (1980) 3.01
RNA-directed DNA synthesis by virions of Rous sarcoma virus: further characterization of the templates and the extent of their transcription. Virology (1973) 3.00
Characteristics of virus-specific RNA in avian sarcoma virus-transformed BHK-21 cells and revertants. Virology (1977) 2.99
Nucleotide sequence of the human N-myc gene. Proc Natl Acad Sci U S A (1986) 2.99