Published in J Am Geriatr Soc on February 01, 1985
The contribution of dietary restriction to extended longevity in the malaria vector Anopheles coluzzii. Parasit Vectors (2017) 0.75
Oxidative stress, caloric restriction, and aging. Science (1996) 11.07
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science (2005) 9.57
Gene expression profile of aging and its retardation by caloric restriction. Science (1999) 8.06
Gene-expression profile of the ageing brain in mice. Nat Genet (2000) 5.46
The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J Nutr (1986) 4.81
Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys. Proc Natl Acad Sci U S A (2001) 3.63
Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence. Science (1982) 3.59
Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents. Proc Natl Acad Sci U S A (1996) 2.23
Dietary restriction of adult male rhesus monkeys: design, methodology, and preliminary findings from the first year of study. J Gerontol (1993) 2.17
Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. Am J Physiol (1994) 2.13
Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study. Exp Gerontol (2000) 2.02
Dietary restriction and aging: the initiation of a primate study. J Gerontol (1990) 1.84
Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart. Physiol Genomics (2003) 1.66
Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle. FASEB J (2000) 1.63
Controlling caloric consumption: protocols for rodents and rhesus monkeys. Neurobiol Aging (1999) 1.61
Restriction of energy intake, energy expenditure, and aging. Free Radic Biol Med (2000) 1.51
Interleukin-6 and aging: blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction. Lymphokine Cytokine Res (1993) 1.49
Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart. Exp Gerontol (2008) 1.49
Dietary restriction benefits learning and motor performance of aged mice. J Gerontol (1987) 1.48
Ageing, oxidative stress, and mitochondrial uncoupling. Acta Physiol Scand (2004) 1.42
Caloric intake and aging: mechanisms in rodents and a study in nonhuman primates. Toxicol Sci (1999) 1.37
Dietary intervention at middle age: caloric restriction but not dehydroepiandrosterone sulfate increases lifespan and lifetime cancer incidence in mice. Cancer Res (1999) 1.36
Influences of dietary restriction and age on liver enzyme activities and lipid peroxidation in mice. J Nutr (1987) 1.32
Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria. Free Radic Biol Med (1998) 1.32
High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys. Mech Ageing Dev (1995) 1.29
Oxidative stress and aging reduce COX I RNA and cytochrome oxidase activity in Drosophila. Free Radic Biol Med (1998) 1.23
Mitotic activity in mice is suppressed by energy restriction-induced torpor. J Nutr (1992) 1.21
Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle. FASEB J (1997) 1.19
Energy expenditure of adult male rhesus monkeys during the first 30 mo of dietary restriction. Am J Physiol (1997) 1.19
Adult-onset energy restriction of rhesus monkeys attenuates oxidative stress-induced cytokine expression by peripheral blood mononuclear cells. J Nutr (1997) 1.19
Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy. Free Radic Biol Med (1998) 1.18
Effect of antioxidants on androgen-induced AP-1 and NF-kappaB DNA-binding activity in prostate carcinoma cells. J Natl Cancer Inst (1999) 1.14
Influences of age and dietary restriction on gastrocnemius electron transport system activities in mice. Arch Biochem Biophys (1996) 1.14
Age-associated alterations of the mitochondrial genome. Free Radic Biol Med (1997) 1.10
Dietary restriction and aging: historical phases, mechanisms and current directions. J Nutr (1987) 1.06
Influences of dietary restriction on immunity to influenza in aged mice. J Gerontol (1991) 1.06
Influence of dietary restriction and aging on natural killer cell activity in mice. J Immunol (1983) 1.05
Multiple mitochondrial DNA deletions associated with age in skeletal muscle of rhesus monkeys. J Gerontol (1993) 1.04
Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys. Mutat Res (2000) 1.02
Caloric restriction and body weight independently affect longevity in Wistar rats. Int J Obes Relat Metab Disord (2004) 1.02
Modification of age-related immune decline in mice dietarily restricted from or after midadulthood. Proc Natl Acad Sci U S A (1982) 1.00
Multiple age-associated mitochondrial DNA deletions in skeletal muscle of mice. Aging (Milano) (1994) 1.00
Age-associated mitochondrial DNA deletions in mouse skeletal muscle: comparison of different regions of the mitochondrial genome. Dev Genet (1996) 0.97
Concerns about rodent models for aging research. J Gerontol (1991) 0.96
Caloric restriction, aging, and antioxidant enzymes. Mutat Res (1993) 0.95
Localization of 4-hydroxy-2-nonenal-modified proteins in kidney following iron overload. Free Radic Biol Med (1999) 0.94
Dietary restriction from middle age attenuates age-associated lymphoma development and interleukin 6 dysregulation in C57BL/6 mice. Cancer Res (1994) 0.93
The prevalence of dysequilibrium and related disorders in older persons. Ear Nose Throat J (1989) 0.92
Caloric restriction in rhesus monkeys reduces low density lipoprotein interaction with arterial proteoglycans. J Gerontol A Biol Sci Med Sci (1998) 0.91
Age-related increase in mitochondrial proton leak and decrease in ATP turnover reactions in mouse hepatocytes. Am J Physiol (1998) 0.91
Androgen-induced oxidative stress in human LNCaP prostate cancer cells is associated with multiple mitochondrial modifications. Antioxid Redox Signal (1999) 0.91
Reduced immune responses in rhesus monkeys subjected to dietary restriction. J Gerontol A Biol Sci Med Sci (1996) 0.90
Influence of caloric restriction on the development of atherosclerosis in nonhuman primates: progress to date. Toxicol Sci (1999) 0.88
Caloric restriction lowers plasma lipoprotein (a) in male but not female rhesus monkeys. Exp Gerontol (2001) 0.88
Dietary restriction attenuates age-related increases in rat skeletal muscle antioxidant enzyme activities. J Gerontol (1994) 0.88
The expression of heat shock protein 70 decreases with age in lymphocytes from rats and rhesus monkeys. Exp Cell Res (1995) 0.86
Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging rats. J Gerontol A Biol Sci Med Sci (2001) 0.86
Caloric restriction improves thermotolerance and reduces hyperthermia-induced cellular damage in old rats. FASEB J (2000) 0.85
Decreased mitochondrial RNA levels without accumulation of mitochondrial DNA deletions in aging Drosophila melanogaster. Mutat Res (1998) 0.85
Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice. Ann N Y Acad Sci (1998) 0.85
Influence of fat intake and caloric restriction on bone in aging male rats. J Gerontol A Biol Sci Med Sci (1997) 0.83
Response to "Interpretation, design, and analysis of gene array expression experiments". J Gerontol A Biol Sci Med Sci (2001) 0.82
Direct repeat sequences are not required at the breakpoints of age-associated mitochondrial DNA deletions in rhesus monkeys. Mech Ageing Dev (1994) 0.82
In vitro oxidation of low-density lipoprotein in two species of nonhuman primates subjected to caloric restriction. J Gerontol A Biol Sci Med Sci (2000) 0.81
Dietary restriction alone and in combination with oral ethoxyquin/2-mercaptoethylamine in mice. J Gerontol (1990) 0.81
The effect of caloric restriction on lipofuscin accumulation in mouse brain with age. Gerontology (1995) 0.81
Prostatic localization of spontaneous early invasive carcinoma in Lobund-Wistar rats. Cancer Res (1994) 0.80
Caloric restriction diminishes the age-associated loss of immunoreactive catalase in rat prostate. Prostate (1997) 0.79
Increased effective activity of rat liver catalase by dietary restriction. Age (Omaha) (1997) 0.78
Neuropeptide Y- and peptide YY-containing colonic cells increase with ageing in male rats. Neuropeptides (1996) 0.78
Food intake reduction and immunologic alterations in mice fed dehydroepiandrosterone. Exp Gerontol (1984) 0.78
Androgen and taxol cause cell type-specific alterations of centrosome and DNA organization in androgen-responsive LNCaP and androgen-independent DU145 prostate cancer cells. J Cell Biochem (2000) 0.77
Influences of aging and dietary restriction on red blood cell density profiles and antioxidant enzyme activities in rhesus monkeys. Exp Gerontol (1994) 0.76
Dietary restriction retards age-related loss of gamma crystallins in the mouse lens. Science (1984) 0.76
A circadian study of liver antioxidant enzyme systems of female Fischer-344 rats subjected to dietary restriction for six weeks. Age (Omaha) (1997) 0.75
Dietary restriction in humans: report on the Little Rock Conference on the value, feasibility, and parameters of a proposed study. Mech Ageing Dev (1996) 0.75
Failure of dietary restriction to retard age-related neurochemical changes in mice. Neurobiol Aging (1993) 0.75