Published in Am J Physiol on August 01, 1998
Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice. PLoS One (2010) 1.57
Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl. Proc Natl Acad Sci U S A (2004) 1.41
Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One (2012) 1.23
Normal brain ageing: models and mechanisms. Philos Trans R Soc Lond B Biol Sci (2005) 1.04
Mitochondrial dysfunction in platelets and hippocampi of senescence-accelerated mice. J Bioenerg Biomembr (2007) 0.90
Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice. Exp Gerontol (2008) 0.88
The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction. Biosci Rep (2012) 0.88
The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction. J Gerontol A Biol Sci Med Sci (2012) 0.87
Test systems to study the structure and function of uncoupling protein 1: a critical overview. Front Endocrinol (Lausanne) (2011) 0.84
Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease. Neurotox Res (2009) 0.77
The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction. Physiol Res (2013) 0.77
The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice. Biogerontology (2015) 0.76
Co-regulation of primary mouse hepatocyte viability and function by oxygen and matrix. Biotechnol Bioeng (2014) 0.75
EFFECTS OF 12 MONTHS OF CALORIC RESTRICTION ON MUSCLE MITOCHONDRIAL FUNCTION IN HEALTHY INDIVIDUALS. J Clin Endocrinol Metab (2016) 0.75
Oxidative stress, caloric restriction, and aging. Science (1996) 11.07
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science (2005) 9.57
Gene expression profile of aging and its retardation by caloric restriction. Science (1999) 8.06
Gene-expression profile of the ageing brain in mice. Nat Genet (2000) 5.46
The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J Nutr (1986) 4.81
Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys. Proc Natl Acad Sci U S A (2001) 3.63
Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence. Science (1982) 3.59
Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents. Proc Natl Acad Sci U S A (1996) 2.23
Dietary restriction of adult male rhesus monkeys: design, methodology, and preliminary findings from the first year of study. J Gerontol (1993) 2.17
Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. Am J Physiol (1994) 2.13
Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study. Exp Gerontol (2000) 2.02
Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3. J Biol Chem (2000) 1.86
Dietary restriction and aging: the initiation of a primate study. J Gerontol (1990) 1.84
Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart. Physiol Genomics (2003) 1.66
Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle. FASEB J (2000) 1.63
Controlling caloric consumption: protocols for rodents and rhesus monkeys. Neurobiol Aging (1999) 1.61
The effect of dietary restriction on body composition in adult male and female rhesus macaques. Aging (Milano) (1998) 1.53
Restriction of energy intake, energy expenditure, and aging. Free Radic Biol Med (2000) 1.51
Interleukin-6 and aging: blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction. Lymphokine Cytokine Res (1993) 1.49
Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart. Exp Gerontol (2008) 1.49
Dietary restriction benefits learning and motor performance of aged mice. J Gerontol (1987) 1.48
Ageing, oxidative stress, and mitochondrial uncoupling. Acta Physiol Scand (2004) 1.42
Caloric intake and aging: mechanisms in rodents and a study in nonhuman primates. Toxicol Sci (1999) 1.37
Dietary intervention at middle age: caloric restriction but not dehydroepiandrosterone sulfate increases lifespan and lifetime cancer incidence in mice. Cancer Res (1999) 1.36
Influences of dietary restriction and age on liver enzyme activities and lipid peroxidation in mice. J Nutr (1987) 1.32
Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria. Free Radic Biol Med (1998) 1.32
High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys. Mech Ageing Dev (1995) 1.29
Oxidative stress and aging reduce COX I RNA and cytochrome oxidase activity in Drosophila. Free Radic Biol Med (1998) 1.23
Caloric restriction mimetics: metabolic interventions. J Gerontol A Biol Sci Med Sci (2001) 1.22
Mitotic activity in mice is suppressed by energy restriction-induced torpor. J Nutr (1992) 1.21
Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle. FASEB J (1997) 1.19
Energy expenditure of adult male rhesus monkeys during the first 30 mo of dietary restriction. Am J Physiol (1997) 1.19
Adult-onset energy restriction of rhesus monkeys attenuates oxidative stress-induced cytokine expression by peripheral blood mononuclear cells. J Nutr (1997) 1.19
Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy. Free Radic Biol Med (1998) 1.18
Effect of antioxidants on androgen-induced AP-1 and NF-kappaB DNA-binding activity in prostate carcinoma cells. J Natl Cancer Inst (1999) 1.14
Influences of age and dietary restriction on gastrocnemius electron transport system activities in mice. Arch Biochem Biophys (1996) 1.14
Age-associated alterations of the mitochondrial genome. Free Radic Biol Med (1997) 1.10
Dietary restriction and aging: historical phases, mechanisms and current directions. J Nutr (1987) 1.06
Influences of dietary restriction on immunity to influenza in aged mice. J Gerontol (1991) 1.06
Influence of dietary restriction and aging on natural killer cell activity in mice. J Immunol (1983) 1.05
Multiple mitochondrial DNA deletions associated with age in skeletal muscle of rhesus monkeys. J Gerontol (1993) 1.04
Caloric restriction and body weight independently affect longevity in Wistar rats. Int J Obes Relat Metab Disord (2004) 1.02
Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys. Mutat Res (2000) 1.02
Modification of age-related immune decline in mice dietarily restricted from or after midadulthood. Proc Natl Acad Sci U S A (1982) 1.00
Multiple age-associated mitochondrial DNA deletions in skeletal muscle of mice. Aging (Milano) (1994) 1.00
Penetrating injury to the heart requiring cardiopulmonary bypass: a case study. J Extra Corpor Technol (2001) 0.99
Age-associated mitochondrial DNA deletions in mouse skeletal muscle: comparison of different regions of the mitochondrial genome. Dev Genet (1996) 0.97
Concerns about rodent models for aging research. J Gerontol (1991) 0.96
Caloric restriction, aging, and antioxidant enzymes. Mutat Res (1993) 0.95
Localization of 4-hydroxy-2-nonenal-modified proteins in kidney following iron overload. Free Radic Biol Med (1999) 0.94
Body fat distribution with long-term dietary restriction in adult male rhesus macaques. J Gerontol A Biol Sci Med Sci (1999) 0.94
Dietary restriction from middle age attenuates age-associated lymphoma development and interleukin 6 dysregulation in C57BL/6 mice. Cancer Res (1994) 0.93
The prevalence of dysequilibrium and related disorders in older persons. Ear Nose Throat J (1989) 0.92
Serum dehydroepiandrosterone sulfate concentrations across the life span of laboratory-housed rhesus monkeys. J Med Primatol (2000) 0.92
Androgen-induced oxidative stress in human LNCaP prostate cancer cells is associated with multiple mitochondrial modifications. Antioxid Redox Signal (1999) 0.91
Caloric restriction in rhesus monkeys reduces low density lipoprotein interaction with arterial proteoglycans. J Gerontol A Biol Sci Med Sci (1998) 0.91
Reduced immune responses in rhesus monkeys subjected to dietary restriction. J Gerontol A Biol Sci Med Sci (1996) 0.90
Dietary restriction attenuates age-related increases in rat skeletal muscle antioxidant enzyme activities. J Gerontol (1994) 0.88
Caloric restriction lowers plasma lipoprotein (a) in male but not female rhesus monkeys. Exp Gerontol (2001) 0.88
Influence of caloric restriction on the development of atherosclerosis in nonhuman primates: progress to date. Toxicol Sci (1999) 0.88
Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging rats. J Gerontol A Biol Sci Med Sci (2001) 0.86
The expression of heat shock protein 70 decreases with age in lymphocytes from rats and rhesus monkeys. Exp Cell Res (1995) 0.86
Caloric restriction improves thermotolerance and reduces hyperthermia-induced cellular damage in old rats. FASEB J (2000) 0.85
Decreased mitochondrial RNA levels without accumulation of mitochondrial DNA deletions in aging Drosophila melanogaster. Mutat Res (1998) 0.85
Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice. Ann N Y Acad Sci (1998) 0.85
Influence of fat intake and caloric restriction on bone in aging male rats. J Gerontol A Biol Sci Med Sci (1997) 0.83
Response to "Interpretation, design, and analysis of gene array expression experiments". J Gerontol A Biol Sci Med Sci (2001) 0.82
Direct repeat sequences are not required at the breakpoints of age-associated mitochondrial DNA deletions in rhesus monkeys. Mech Ageing Dev (1994) 0.82
Resting energy expenditure and body composition of Labrador Retrievers fed high fat and low fat diets. J Anim Physiol Anim Nutr (Berl) (2006) 0.81
In vitro oxidation of low-density lipoprotein in two species of nonhuman primates subjected to caloric restriction. J Gerontol A Biol Sci Med Sci (2000) 0.81
The effect of caloric restriction on lipofuscin accumulation in mouse brain with age. Gerontology (1995) 0.81
Dietary restriction alone and in combination with oral ethoxyquin/2-mercaptoethylamine in mice. J Gerontol (1990) 0.81
Prostatic localization of spontaneous early invasive carcinoma in Lobund-Wistar rats. Cancer Res (1994) 0.80
UCP3 and its putative function: consistencies and controversies. Biochem Soc Trans (2001) 0.79
Caloric restriction diminishes the age-associated loss of immunoreactive catalase in rat prostate. Prostate (1997) 0.79
Influence of a high-protein diet on energy balance in obese cats allowed ad libitum access to food. J Anim Physiol Anim Nutr (Berl) (2010) 0.79
Neuropeptide Y- and peptide YY-containing colonic cells increase with ageing in male rats. Neuropeptides (1996) 0.78
Food intake reduction and immunologic alterations in mice fed dehydroepiandrosterone. Exp Gerontol (1984) 0.78
Increased effective activity of rat liver catalase by dietary restriction. Age (Omaha) (1997) 0.78
Differences in mitochondrial efficiency between lines of mice divergently selected for heat loss. J Anim Sci (2009) 0.78
Influence of dietary protein level on body composition and energy expenditure in calorically restricted overweight cats. J Anim Physiol Anim Nutr (Berl) (2014) 0.77
The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction. Physiol Res (2013) 0.77
Androgen and taxol cause cell type-specific alterations of centrosome and DNA organization in androgen-responsive LNCaP and androgen-independent DU145 prostate cancer cells. J Cell Biochem (2000) 0.77
Dietary restriction retards age-related loss of gamma crystallins in the mouse lens. Science (1984) 0.76
Aging in rodents fed restricted diets. J Am Geriatr Soc (1985) 0.76
Influences of aging and dietary restriction on red blood cell density profiles and antioxidant enzyme activities in rhesus monkeys. Exp Gerontol (1994) 0.76
A circadian study of liver antioxidant enzyme systems of female Fischer-344 rats subjected to dietary restriction for six weeks. Age (Omaha) (1997) 0.75
Dietary restriction in humans: report on the Little Rock Conference on the value, feasibility, and parameters of a proposed study. Mech Ageing Dev (1996) 0.75
Failure of dietary restriction to retard age-related neurochemical changes in mice. Neurobiol Aging (1993) 0.75