Improved free-energy parameters for predictions of RNA duplex stability.

PubWeight™: 19.52‹?› | Rank: Top 0.1% | All-Time Top 10000

🔗 View Article (PMC 387140)

Published in Proc Natl Acad Sci U S A on December 01, 1986

Authors

S M Freier, R Kierzek, J A Jaeger, N Sugimoto, M H Caruthers, T Neilson, D H Turner

Articles citing this

(truncated to the top 100)

Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89

A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. Proc Natl Acad Sci U S A (1998) 24.28

Improved predictions of secondary structures for RNA. Proc Natl Acad Sci U S A (1989) 11.52

ViennaRNA Package 2.0. Algorithms Mol Biol (2011) 9.43

Coaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA folding. Proc Natl Acad Sci U S A (1994) 8.06

Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end. Proc Natl Acad Sci U S A (1991) 7.13

A computer program for choosing optimal oligonucleotides for filter hybridization, sequencing and in vitro amplification of DNA. Nucleic Acids Res (1989) 6.28

CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes. Proc Natl Acad Sci U S A (1988) 5.50

Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference. Nucleic Acids Res (2004) 5.46

Improved thermodynamic parameters and helix initiation factor to predict stability of DNA duplexes. Nucleic Acids Res (1996) 5.16

Thermodynamic parameters for DNA sequences with dangling ends. Nucleic Acids Res (2000) 5.11

Molecular cloning of hepatitis delta virus RNA from an infected woodchuck liver: sequence, structure, and applications. J Virol (1988) 4.96

"Well-determined" regions in RNA secondary structure prediction: analysis of small subunit ribosomal RNA. Nucleic Acids Res (1995) 4.87

Optimization of the annealing temperature for DNA amplification in vitro. Nucleic Acids Res (1990) 4.72

Secondary structure of the 5' nontranslated regions of hepatitis C virus and pestivirus genomic RNAs. Nucleic Acids Res (1992) 4.58

Secondary structure of the ribosome binding site determines translational efficiency: a quantitative analysis. Proc Natl Acad Sci U S A (1990) 4.45

A computer analysis of primer and probe hybridization potential with bacterial small-subunit rRNA sequences. Appl Environ Microbiol (1996) 3.92

The yeast homologue of U3 snRNA. EMBO J (1987) 3.74

A thermodynamic study of unusually stable RNA and DNA hairpins. Nucleic Acids Res (1991) 3.59

Sequence and structural elements that contribute to efficient encephalomyocarditis virus RNA translation. J Virol (1992) 3.28

Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA. Proc Natl Acad Sci U S A (1988) 3.23

Automatic detection of conserved RNA structure elements in complete RNA virus genomes. Nucleic Acids Res (1998) 3.18

Interaction between retroviral U5 RNA and the T psi C loop of the tRNA(Trp) primer is required for efficient initiation of reverse transcription. J Virol (1992) 3.06

Characterization of leucocin A-UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum. J Bacteriol (1991) 3.02

Tourist: a large family of small inverted repeat elements frequently associated with maize genes. Plant Cell (1992) 2.95

Osprey: a comprehensive tool employing novel methods for the design of oligonucleotides for DNA sequencing and microarrays. Nucleic Acids Res (2004) 2.91

Role of the DIS hairpin in replication of human immunodeficiency virus type 1. J Virol (1996) 2.87

The 5' nontranslated region of hepatitis A virus RNA: secondary structure and elements required for translation in vitro. J Virol (1991) 2.83

The initiation of translation in E. coli: apparent base pairing between the 16srRNA and downstream sequences of the mRNA. Nucleic Acids Res (1990) 2.81

Base-stacking and base-pairing contributions into thermal stability of the DNA double helix. Nucleic Acids Res (2006) 2.78

The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum. Genetics (1992) 2.71

Thermodynamic parameters for loop formation in RNA and DNA hairpin tetraloops. Nucleic Acids Res (1992) 2.70

Thermal denaturation of double-stranded nucleic acids: prediction of temperatures critical for gradient gel electrophoresis and polymerase chain reaction. Nucleic Acids Res (1994) 2.64

Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure prediction. BMC Bioinformatics (2004) 2.57

A comparison of optimal and suboptimal RNA secondary structures predicted by free energy minimization with structures determined by phylogenetic comparison. Nucleic Acids Res (1991) 2.51

Human immunodeficiency virus type 1 gag-pol frameshifting is dependent on downstream mRNA secondary structure: demonstration by expression in vivo. J Virol (1992) 2.49

Correlations between Shine-Dalgarno sequences and gene features such as predicted expression levels and operon structures. J Bacteriol (2002) 2.47

An accurate and interpretable model for siRNA efficacy prediction. BMC Bioinformatics (2006) 2.46

A point mutation G----A in exon 12 of the porphobilinogen deaminase gene results in exon skipping and is responsible for acute intermittent porphyria. Nucleic Acids Res (1989) 2.39

'Hairpin' catalytic RNA model: evidence for helices and sequence requirement for substrate RNA. Nucleic Acids Res (1990) 2.38

Primer design for large scale sequencing. Nucleic Acids Res (1998) 2.31

Enhancement of the seed-target recognition step in RNA silencing by a PIWI/MID domain protein. Mol Cell (2009) 2.27

Group-specific identification of polioviruses by PCR using primers containing mixed-base or deoxyinosine residue at positions of codon degeneracy. J Clin Microbiol (1996) 2.23

Simian immunodeficiency virus RNA is efficiently encapsidated by human immunodeficiency virus type 1 particles. J Virol (1993) 2.17

A more unified picture for the thermodynamics of nucleic acid duplex melting: a characterization by calorimetric and volumetric techniques. Proc Natl Acad Sci U S A (1999) 2.16

Cloning and characterization of a Rhizobium meliloti homolog of the Escherichia coli cell division gene ftsZ. J Bacteriol (1991) 2.13

Unusual branch point selection in processing of human growth hormone pre-mRNA. Mol Cell Biol (1988) 2.12

Implications of ribozyme kinetics for targeting the cleavage of specific RNA molecules in vivo: more isn't always better. Proc Natl Acad Sci U S A (1991) 2.09

Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other. Nucleic Acids Res (1988) 2.08

Molecular characterization of the dnaK gene region of Clostridium acetobutylicum, including grpE, dnaJ, and a new heat shock gene. J Bacteriol (1992) 2.06

A common RNA structural motif involved in the internal initiation of translation of cellular mRNAs. Nucleic Acids Res (1997) 2.05

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1. Proc Natl Acad Sci U S A (1991) 2.04

In vitro assembly of cubic RNA-based scaffolds designed in silico. Nat Nanotechnol (2010) 1.96

Transcriptional regulation of the ilv-leu operon of Bacillus subtilis. J Bacteriol (1992) 1.96

Nucleocytoplasmic transport and processing of small nuclear RNA precursors. Mol Cell Biol (1990) 1.96

Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein. Proc Natl Acad Sci U S A (1992) 1.96

Cis-element, oriR, involved in the initiation of (-) strand poliovirus RNA: a quasi-globular multi-domain RNA structure maintained by tertiary ('kissing') interactions. EMBO J (1996) 1.94

Serotype-specific identification of polioviruses by PCR using primers containing mixed-base or deoxyinosine residues at positions of codon degeneracy. J Clin Microbiol (1998) 1.93

Messenger RNA recognition in Escherichia coli: a possible second site of interaction with 16S ribosomal RNA. EMBO J (1988) 1.91

A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses. Nucleic Acids Res (1990) 1.90

Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena. Proc Natl Acad Sci U S A (1990) 1.88

Defined mutations in the 5' nontranslated sequence of Sindbis virus RNA. J Virol (1990) 1.87

Dual translational initiation sites control function of the lambda S gene. EMBO J (1989) 1.87

Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA. Mol Cell Biol (1993) 1.85

The 7S RNA from tomato leaf tissue resembles a signal recognition particle RNA and exhibits a remarkable sequence complementarity to viroids. EMBO J (1988) 1.84

Exon as well as intron sequences are cis-regulating elements for the mutually exclusive alternative splicing of the beta tropomyosin gene. Mol Cell Biol (1990) 1.82

Cloning, sequencing, and molecular analysis of the groESL operon of Clostridium acetobutylicum. J Bacteriol (1992) 1.82

Filler DNA is associated with spontaneous deletions in maize. Proc Natl Acad Sci U S A (1990) 1.81

Accumulation of U14 small nuclear RNA in Saccharomyces cerevisiae requires box C, box D, and a 5', 3' terminal stem. Mol Cell Biol (1992) 1.80

Transcript elongation and termination are competitive kinetic processes. Proc Natl Acad Sci U S A (1991) 1.75

An intronic splicing enhancer binds U1 snRNPs to enhance splicing and select 5' splice sites. Mol Cell Biol (2000) 1.75

Evolution of a disrupted TAR RNA hairpin structure in the HIV-1 virus. EMBO J (1994) 1.74

Temperature sensing in Yersinia pestis: translation of the LcrF activator protein is thermally regulated. J Bacteriol (1993) 1.73

Replication control of plasmid R1: RepA synthesis is regulated by CopA RNA through inhibition of leader peptide translation. EMBO J (1992) 1.70

Hammerhead ribozymes: importance of stem-loop II for activity. Proc Natl Acad Sci U S A (1993) 1.69

Computational models with thermodynamic and composition features improve siRNA design. BMC Bioinformatics (2006) 1.69

Secondary structure model of the RNA recognized by the reverse transcriptase from the R2 retrotransposable element. RNA (1997) 1.68

A specific 31-nucleotide domain of U1 RNA directly interacts with the 70K small nuclear ribonucleoprotein component. Mol Cell Biol (1989) 1.68

Phenotypic and genetic characterization of the bacteriophage abortive infection mechanism AbiK from Lactococcus lactis. Appl Environ Microbiol (1997) 1.67

Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium. Proc Natl Acad Sci U S A (2000) 1.67

The secondary structure of guide RNA molecules from Trypanosoma brucei. Nucleic Acids Res (1995) 1.66

Translational control of pyrC expression mediated by nucleotide-sensitive selection of transcriptional start sites in Escherichia coli. J Bacteriol (1992) 1.65

Identification of vaccine-related polioviruses by hybridization with specific RNA probes. J Clin Microbiol (1995) 1.65

Nucleic acid helix stability: effects of salt concentration, cation valence and size, and chain length. Biophys J (2005) 1.64

An analytical study of the dimerization of in vitro generated RNA of Moloney murine leukemia virus MoMuLV. Nucleic Acids Res (1990) 1.62

Force-induced denaturation of RNA. Biophys J (2001) 1.62

On the stability of nucleic acid structures in solution: enthalpy-entropy compensations, internal rotations and reversibility. Nucleic Acids Res (1993) 1.60

Direct evolution of genetic robustness in microRNA. Proc Natl Acad Sci U S A (2006) 1.59

RNA misfolding and the action of chaperones. Front Biosci (2008) 1.59

Splicing mutants and their second-site suppressors at the dihydrofolate reductase locus in Chinese hamster ovary cells. Mol Cell Biol (1993) 1.58

A double hairpin structure is necessary for the efficient encapsidation of spleen necrosis virus retroviral RNA. EMBO J (1994) 1.58

The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn. J Exp Med (1993) 1.58

Regulation of pyrimidine biosynthetic gene expression in bacteria: repression without repressors. Microbiol Mol Biol Rev (2008) 1.57

Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene. Mol Cell Biol (1993) 1.57

Defining functional groups, core structural features and inter-domain tertiary contacts essential for group II intron self-splicing: a NAIM analysis. EMBO J (1998) 1.57

Targeted cleavage of mRNA in vitro by RNase P from Escherichia coli. Proc Natl Acad Sci U S A (1992) 1.56

Predicting Shine-Dalgarno sequence locations exposes genome annotation errors. PLoS Comput Biol (2006) 1.55

Protein S1 counteracts the inhibitory effect of the extended Shine-Dalgarno sequence on translation. RNA (2002) 1.55

Ribosomal protein S14 genes in broad bean mitochondrial DNA. Nucleic Acids Res (1988) 1.54

Stability of RNA stem-loop structure and distribution of non-random structure in the human immunodeficiency virus (HIV-I). Nucleic Acids Res (1988) 1.54

Articles cited by this

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. Nucleic Acids Res (1981) 61.59

Improved estimation of secondary structure in ribonucleic acids. Nat New Biol (1973) 46.33

Detailed analysis of the higher-order structure of 16S-like ribosomal ribonucleic acids. Microbiol Rev (1983) 23.08

Estimation of secondary structure in ribonucleic acids. Nature (1971) 20.52

Stability of ribonucleic acid double-stranded helices. J Mol Biol (1974) 16.35

Globin mRNA sequences: analysis of base pairing and evolutionary implications. Cold Spring Harb Symp Quant Biol (1978) 13.15

Free energy of imperfect nucleic acid helices. II. Small hairpin loops. J Mol Biol (1973) 10.07

Free energy of imperfect nucleic acid helices. 3. Small internal loops resulting from mismatches. J Mol Biol (1973) 8.74

Base-stacking and base-pairing contributions to helix stability: thermodynamics of double-helix formation with CCGG, CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp. Biochemistry (1983) 6.81

Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: structural homology with fungal mitochondrial intervening sequences. Proc Natl Acad Sci U S A (1983) 4.78

Relaxation kinetics of dimer formation by self complementary oligonucleotides. J Mol Biol (1971) 4.77

Self-complementary oligoribonucleotides: effects of helix defects and guanylic acid-cytidylic acid base pairs. J Mol Biol (1971) 4.54

Some simple computational methods to improve the folding of large RNAs. Nucleic Acids Res (1984) 3.69

Thermodynamics of (dG--dC)3 double-helix formation in water and deuterium oxide. Biochemistry (1981) 3.30

Calorimetric and spectroscopic investigation of the helix-to-coil transition of a ribo-oligonucleotide: rA7U7. J Mol Biol (1975) 2.84

Thermodynamic studies of RNA stability. J Biomol Struct Dyn (1984) 2.75

Contributions of dangling end stacking and terminal base-pair formation to the stabilities of XGGCCp, XCCGGp, XGGCCYp, and XCCGGYp helixes. Biochemistry (1985) 2.70

DNA and RNA oligomer thermodynamics: the effect of mismatched bases on double-helix stability. Biopolymers (1981) 2.62

The 3' terminus of 16S rRNA: secondary structure and interaction with ribosomal protein S1. Nucleic Acids Res (1979) 2.51

An energy model that predicts the correct folding of both the tRNA and the 5S RNA molecules. Nucleic Acids Res (1984) 2.38

Stability of XGCGCp, GCGCYp, and XGCGCYp helixes: an empirical estimate of the energetics of hydrogen bonds in nucleic acids. Biochemistry (1986) 2.32

The conformational transitions in yeast tRNAPhe as studied with tRNAPhe fragments. Eur J Biochem (1973) 2.26

Helix formation by d(TA) oligomers. II. Analysis of the helix-coli transitions of linear and circular oligomers. J Mol Biol (1970) 2.26

Computer-aided prediction of RNA secondary structures. Nucleic Acids Res (1982) 2.14

Conformational transitions in viroids and virusoids: comparison of results from energy minimization algorithm and from experimental data. J Biomol Struct Dyn (1984) 2.14

Small changes in free energy assignments for unpaired bases do not affect predicted secondary structures in single stranded RNA. Nucleic Acids Res (1982) 2.14

Energetics of internal GU mismatches in ribooligonucleotide helixes. Biochemistry (1986) 1.92

Free energy contributions of G.U and other terminal mismatches to helix stability. Biochemistry (1986) 1.92

Conformational transitions in tRNA Asp (brewer's yeast). Thermodynamic, kinetic, and enzymatic measurements on oligonucleotide fragments and the intact molecule. Biochemistry (1974) 1.82

Solvent effects on the stability of A7U7p. Biochemistry (1985) 1.73

Free energy of imperfect nucleic acid helices. I. The bulge defect. J Mol Biol (1972) 1.63

Heat of the reaction forming the three-stranded poly (A + 2U) complex. Biopolymers (1965) 1.44

Calorimetric determination of the heat capacity changes associated with the conformational transitions of polyriboadenylic acid and polyribouridylic acid. Biopolymers (1977) 1.44

The effects of base sequence and dangling bases on the stability of short ribonucleic acid duplexes. Nucleic Acids Symp Ser (1980) 1.42

Theory of oligonucleotide stabilization. I. The effect of single-strand stacking. Biopolymers (1973) 1.42

Improved free energies for G.C base-pairs. J Mol Biol (1985) 1.31

Articles by these authors

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J Mol Biol (1999) 41.48

Improved predictions of secondary structures for RNA. Proc Natl Acad Sci U S A (1989) 11.52

Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs. Biochemistry (1998) 9.75

PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature (1993) 8.83

Coaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA folding. Proc Natl Acad Sci U S A (1994) 8.06

Predicting optimal and suboptimal secondary structure for RNA. Methods Enzymol (1990) 7.08

Base-stacking and base-pairing contributions to helix stability: thermodynamics of double-helix formation with CCGG, CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp. Biochemistry (1983) 6.81

RNA structure prediction. Annu Rev Biophys Biophys Chem (1988) 5.75

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site. Nature (1982) 5.61

Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3' consensus sequence AAUAAA. Nature (1983) 5.18

Gene synthesis machines: DNA chemistry and its uses. Science (1985) 4.76

In situ activation of bis-dialkylaminophosphines--a new method for synthesizing deoxyoligonucleotides on polymer supports. Nucleic Acids Res (1984) 4.55

Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression. J Biol Chem (1993) 3.70

The effect of acceptor oligoribonucleotide sequence on the T4 RNA ligase reaction. Eur J Biochem (1982) 3.51

Predicting thermodynamic properties of RNA. Methods Enzymol (1995) 3.38

Thermodynamics of (dG--dC)3 double-helix formation in water and deuterium oxide. Biochemistry (1981) 3.30

Polymer-supported RNA synthesis and its application to test the nearest-neighbor model for duplex stability. Biochemistry (1986) 3.21

Investigation of the structural basis for thermodynamic stabilities of tandem GU mismatches: solution structure of (rGAGGUCUC)2 by two-dimensional NMR and simulated annealing. Biochemistry (1996) 2.96

Binding of synthetic lactose operator DNAs to lactose represessors. Proc Natl Acad Sci U S A (1977) 2.86

Thermodynamic studies of RNA stability. J Biomol Struct Dyn (1984) 2.75

Contributions of dangling end stacking and terminal base-pair formation to the stabilities of XGGCCp, XCCGGp, XGGCCYp, and XCCGGYp helixes. Biochemistry (1985) 2.70

Predicting oligonucleotide affinity to nucleic acid targets. RNA (1999) 2.67

Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. J Biol Chem (1991) 2.65

Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature (1993) 2.62

Total synthesis of the gene for an alanine transfer ribonucleic acid from yeast. Nature (1970) 2.51

A comparison of optimal and suboptimal RNA secondary structures predicted by free energy minimization with structures determined by phylogenetic comparison. Nucleic Acids Res (1991) 2.51

Stabilities of consecutive A.C, C.C, G.G, U.C, and U.U mismatches in RNA internal loops: Evidence for stable hydrogen-bonded U.U and C.C.+ pairs. Biochemistry (1991) 2.44

Context dependence of hydrogen bond free energy revealed by substitutions in an RNA hairpin. Science (1992) 2.44

Thermodynamics of single mismatches in RNA duplexes. Biochemistry (1999) 2.36

Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J Med Chem (1993) 2.34

Stability of XGCGCp, GCGCYp, and XGCGCYp helixes: an empirical estimate of the energetics of hydrogen bonds in nucleic acids. Biochemistry (1986) 2.32

New chemical methods for synthesizing polynucleotides. Nucleic Acids Symp Ser (1980) 2.32

Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity. Nucleic Acids Res (1995) 2.30

Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR. RNA (2000) 2.25

Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxin. J Cell Biol (1997) 2.25

Implication of RNA structure on antisense oligonucleotide hybridization kinetics. Biochemistry (1992) 2.17

How lac repressor recognizes lac operator. Proc Natl Acad Sci U S A (1978) 2.15

Thermal unfolding of a group I ribozyme: the low-temperature transition is primarily disruption of tertiary structure. Biochemistry (1993) 2.13

Laser temperature-jump, spectroscopic, and thermodynamic study of salt effects on duplex formation by dGCATGC. Biochemistry (1989) 2.13

Laser temperature-jump study of stacking in adenylic acid polymers. Biochemistry (1979) 2.12

Improved parameters for prediction of RNA structure. Cold Spring Harb Symp Quant Biol (1987) 2.08

Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides. J Biol Chem (1992) 1.99

Sequence dependence for the energetics of dangling ends and terminal base pairs in ribonucleic acid. Biochemistry (1987) 1.95

Energetics of internal GU mismatches in ribooligonucleotide helixes. Biochemistry (1986) 1.92

Phosphorodithioate DNA as a potential therapeutic drug. Science (1993) 1.92

Free energy contributions of G.U and other terminal mismatches to helix stability. Biochemistry (1986) 1.92

Writing waveguides in glass with a femtosecond laser. Opt Lett (1996) 1.91

Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo. J Biol Chem (1997) 1.91

Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction. J Biol Chem (1976) 1.91

Studies on polynucleotides. 103. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. J Mol Biol (1972) 1.90

Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3. Mol Cell Biol (2000) 1.90

Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection. Nucleic Acids Res (1991) 1.80

Thermodynamics of three-way multibranch loops in RNA. Biochemistry (2001) 1.78

Effects of GA mismatches on the structure and thermodynamics of RNA internal loops. Biochemistry (1990) 1.76

Solvent effects on the stability of A7U7p. Biochemistry (1985) 1.73

Thermodynamic study of internal loops in oligoribonucleotides: symmetric loops are more stable than asymmetric loops. Biochemistry (1991) 1.71

Oligodeoxynucleotides containing 2'-O-modified adenosine: synthesis and effects on stability of DNA:RNA duplexes. Biochemistry (1993) 1.71

Studies on gene control regions XII. The functional significance of a lac operator constitutive mutation. Nucleic Acids Res (1979) 1.70

Nearest-neighbor parameters for G.U mismatches: [formula; see text] is destabilizing in the contexts [formula; see text] and [formula; see text] but stabilizing in [formula; see text]. Biochemistry (1991) 1.70

Structure of (rGGCGAGCC)2 in solution from NMR and restrained molecular dynamics. Biochemistry (1993) 1.70

Dynamics of ribozyme binding of substrate revealed by fluorescence-detected stopped-flow methods. Science (1992) 1.69

Secondary structure model of the RNA recognized by the reverse transcriptase from the R2 retrotransposable element. RNA (1997) 1.68

Nucleoside-3'-phosphotriesters as key intermediates for the oligoribonucleotide synthesis. III. An improved preparation of nucleoside 3'-phosphotriesters, their 1H NMR characterization and new conditions for removal of 2-cyanoethyl group. Nucleic Acids Res (1976) 1.66

Relative thermodynamic stability of DNA, RNA, and DNA:RNA hybrid duplexes: relationship with base composition and structure. Biochemistry (1995) 1.65