Published in J Exp Med on March 01, 1978
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Generation and characterization of a lipopolysaccharide-induced and serum-derived cytotoxic factor for tumor cells. Infect Immun (1980) 2.12
Cellular requirements for lipopolysaccharide adjuvanticity. A role for both T lymphocytes and macrophages for in vitro responses to particulate antigens. J Exp Med (1979) 1.73
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The use of bacterial lipopolysaccharides to show that two signals are required for the induction of antibody synthesis. J Exp Med (1973) 2.30
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Effects of bacterial endotoxin on rabbit platelets. I. Platelet aggregation and release of platelet factors in vitro. J Exp Med (1961) 2.17
Termination of tolerance to human gamma globulin in mice by antigen and bacterial lipopolysaccharide (endotoxin). J Exp Med (1973) 2.15
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Failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice. Infect Immun (1976) 1.71
Cellular site of action of various adjuvants in antibody responses to hapten-carrier conjugates. J Immunol (1973) 1.62
Inhibition of the mitogenic response to lipopolysaccharide (LPS) in mouse spleen cells by polymyxin B. J Immunol (1977) 1.57
The ability of bacterial lipopolysaccharide to modulate the induction of unresponsiveness to a state of immunity. Cellular parameters. J Exp Med (1973) 1.49
Studies on the induction of immunologic unresponsiveness. I. Effects of endotoxin and phytochemagglutinin. J Immunol (1967) 1.47
Regulation of lymphocyte responses in vitro. I. Regulatory effect of macrophages and thymus-dependent (T) cells on the response of thymus-independent (B) lymphocytes to endotoxin. J Exp Med (1972) 1.40
Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol. J Exp Med (1977) 1.37
Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS. J Exp Med (1976) 1.34
Specific suppression of the immune response by HGG tolerant spleen cells. I. Parameters affecting the level of suppression. J Immunol (1976) 1.30
Differentiation of lymphoid cells: B cell as a direct target and T cell as a regulator in lipopolysaccharide-enhanced induction of immunoglobulin production. J Immunol (1976) 1.13
Induction of immunological tolerance to a thymus-dependent antigen in the absence of thymus-derived cells. J Exp Med (1974) 1.12
Effect of lipopolysaccharide on immunogenicity and tolerogenicity of HGG in C57BL/6J nude mice: evidence for a possible B cell deficiency. J Immunol (1977) 1.02
Macrophages suppress direct B-cell activation by lipopolysaccharide. Scand J Immunol (1975) 1.00
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Effect of lipopolysaccharide and lipid A on mouse liver pyruvate kinase activity. Infect Immun (1975) 0.85
Antigen recognition. IV. Discrimination by antigen-binding immunocompetent B cells between immunity and tolerance is determined by adherent cells. J Exp Med (1976) 0.81
The effect of lipopolysaccharide on the primary immune response to the hapten NNP. Scand J Immunol (1975) 0.80
Effect of polyclonal B-cell activators on DNA synthesis in fibroblasts. Scand J Immunol (1975) 0.77
Kinetic differences in unresponsiveness of thymus and bone marrow cells. Science (1971) 4.13
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
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Immunologic properties of bacterial lipopolysaccharide (LPS): correlation between the mitogenic, adjuvant, and immunogenic activities. J Immunol (1975) 3.18
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Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. Proc Natl Acad Sci U S A (1973) 2.61
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Analysis of autoimmunity through experimental models of thyroiditis and allergic encephalomyelitis. Adv Immunol (1980) 2.27
Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS. J Exp Med (1975) 2.22
Termination of tolerance to human gamma globulin in mice by antigen and bacterial lipopolysaccharide (endotoxin). J Exp Med (1973) 2.15
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The production of thyroiditis and antibody following injection of unaltered thyroglobulin without adjuvant into rabbits previously stimulated with altered thyroglobulin. J Exp Med (1965) 1.96
The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J Immunol (1993) 1.88
The production of antisera to human gammaGlobulin subclasses in rabbits using immunological unresponsiveness. J Immunol (1968) 1.82
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Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. J Immunol (1990) 1.79
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Cellular events in the induction of experimental allergic encephalomyelitis in rats. J Exp Med (1976) 1.69
The cellular and subcellular bases of immunosenescence. Adv Immunol (1989) 1.59
B-lymphocytes activation by the Fc region of IgG. J Exp Med (1977) 1.51
Cyclical production of antibody as a regulatory mechanism in the immune response. Adv Immunol (1975) 1.50
The ability of bacterial lipopolysaccharide to modulate the induction of unresponsiveness to a state of immunity. Cellular parameters. J Exp Med (1973) 1.49
Interstitial immune complex thyroiditis in mice: the role of autoantibody to thyroglobulin. J Exp Med (1974) 1.49
Lymphokines and aging: interleukin-2 production and activity in aged animals. J Immunol (1981) 1.48
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Regulation of immune response by components of the complement cascade and their activated fragments. Springer Semin Immunopathol (1983) 1.41
Roles of T and B lymphocytes in the termination of unresponsiveness to autologous thyroglobulin in mice. J Exp Med (1974) 1.38
Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol. J Exp Med (1977) 1.37
Effect of chronic viral infection on the immune system. I. Comparison of the immune responsiveness of mice chronically infected with LCM virus with that of noninfected mice. J Immunol (1973) 1.36
The development of autoimmune thyroiditis in rabbits following injection of aqueous preparations of heterologous thyroglobulins. J Immunol (1967) 1.35
Induction of interleukin 1 secretion and enhancement of humoral immunity by binding of human C5a to macrophage surface C5a receptors. J Exp Med (1982) 1.35
Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS. J Exp Med (1976) 1.34
Cell-mediated immunity in aged mice: an underlying lesion in IL 2 synthesis. J Immunol (1982) 1.33
CD4+ T cell activation and tolerance induction in B cell knockout mice. J Exp Med (1996) 1.32
Th1 and Th2 clones differ in their response to a tolerogenic signal. J Immunol (1990) 1.31
Specific suppression of the immune response by HGG tolerant spleen cells. I. Parameters affecting the level of suppression. J Immunol (1976) 1.30
Induction and mode of action of suppressor cells generated against human gamma globulin. I. An immunologic unresponsive state devoid of demonstrable suppressor cells. J Exp Med (1978) 1.29
Transfer of experimental autoimmune thyroiditis with T cell clones. J Immunol (1987) 1.28
Demonstration of a specific receptor for human C5a anaphylatoxin on murine macrophages. J Exp Med (1982) 1.28
Tolerogenicity of resting and activated B cells. J Exp Med (1994) 1.25
The immune response to human gamma-G-immunoglobulin in rabbits unresponsive to Fc fragment and H chain protein. J Immunol (1967) 1.25
The termination of immunological unresponsiveness to bovine serum albumin in rabbits. I. Quantitative and qualitative response to cross-reacting albumins. J Exp Med (1970) 1.24
In vivo induction of tolerance in murine CD4+ cell subsets. J Exp Med (1993) 1.22
T cell regulation of polyclonal B cell responsiveness. I. Helper effects of T cells. J Immunol (1979) 1.21
Fate of antigen-binding cells in unresponsive and immune mice. J Exp Med (1973) 1.20
Immunologic unresponsiveness after gastric administration of human gamma-globulin: antigen requirements and cellular parameters. J Immunol (1980) 1.20
The effect of antigenic competition on antibody production to heterologous proteins, termination of immunologic unresponsiveness and induction of autoimmunity. J Immunol (1967) 1.17
The requirement for adherent cells in the Fc fragment-induced proliferative response of murine spleen cells. J Exp Med (1979) 1.15
Specific, transient suppression of the immune response by HGG tolerant spleen cells. II. Effector cells and target cells. J Immunol (1976) 1.14
The behavior of autologous thyroglobulin in the circulation of rabbits immunized with either heterologous or altered homologous thyroglobulin. J Immunol (1967) 1.13
The role of phagocytosis and natural lymphokines in the fusion of alveolar macrophages to form Langhans giant cells. J Reticuloendothel Soc (1975) 1.13
Regulation of Fc fragment-induced murine spleen cell proliferation. J Exp Med (1980) 1.12
Studies on the catabolism of gamma- G subunits and chains. J Immunol (1965) 1.10
The induction of peripheral T cell unresponsiveness in adult mice by monomeric human gamma-globulin. J Immunol (1989) 1.09
Splenic role in the regulation of immune responses. Cell Immunol (1977) 1.09
2,4-Dinitrophenyl receptors on mouse thymus and spleen cells. J Exp Med (1973) 1.07
Inability of the C3a anaphylatoxin to promote cellular lysis. Nature (1980) 1.07
Th1 cell anergy and blockade in G1a phase of the cell cycle. J Immunol (1993) 1.07
Possible roles of suppressor cells in immunologic tolerance. Transplant Rev (1975) 1.07
Anti-bovine serum albumin specificity and binding affinity after termination of tolerance to bovine serum albumin. J Immunol (1965) 1.06
Role of C3 in the regulation of a splenic PFC response in rabbits. J Immunol (1980) 1.05
The C5a receptor of neutrophils and macrophages. Agents Actions Suppl (1983) 1.05
Polyclonal activation of murine B lymphocytes by Fc fragments. I. The requirement for two signals in the generation of the polyclonal antibody response induced by Fc fragments. J Immunol (1980) 1.04
Passive transfer of experimental allergic encephalomyelitis by myelin basic protein-specific L3T4+ T cell clones possessing several functions. J Immunol (1986) 1.04
Polyclonal B lymphocyte activation during Trypanosoma cruzi infection. J Immunol (1980) 1.03
The in vivo formation and fate of antigen-antibody complexes formed by fragments and polypeptide chains of rabbit gamma-G-antibodies. J Exp Med (1966) 1.03
The antibody response in rabbits to previously tolerated antigens. Ann N Y Acad Sci (1965) 1.03
In vivo behavior of homologous and heterologous thyroglobulin and induction of immunologic unresponsiveness to heterologous thyroglobulin. J Immunol (1967) 1.03
Regulation of the immune response. I. The potentiation of in vivo and in vitro immune responses by Fc fragments. J Exp Med (1980) 1.02
Effect of lipopolysaccharide on immunogenicity and tolerogenicity of HGG in C57BL/6J nude mice: evidence for a possible B cell deficiency. J Immunol (1977) 1.02
Anaphylatoxin-mediated regulation of the immune response. II. C5a-mediated enhancement of human humoral and T cell-mediated immune responses. J Immunol (1983) 1.02
Nonspecific activation of murine lymphocytes. IV. Proliferation of a distinct, late maturing lymphocyte subpopulation induced by 2-mercaptoethanol. J Immunol (1978) 1.02
Separation of various B-cell subpopulations from mouse spleen. I. Depletion of B cells by rosetting with glutaraldehyde-fixed, anti-immunoglobulin-coupled red blood cells. Cell Immunol (1979) 1.01
Fc fragment activation of T lymphocytes. I. Fc fragments trigger Lyt 1+23- T lymphocytes to release a helper T cell-replacing activity. J Immunol (1981) 1.01
Nonspecific activation of murine lymphocytes. V. Role of cellular collaboration between T and B lymphocytes in the proliferative and polyclonal response to 2-mercaptoethanol. J Immunol (1979) 1.01
Identification and characterization of the effector region within human C5a responsible for stimulation of IL-6 synthesis. J Immunol (1992) 1.01
Potentiation of the primary humoral immune response in vitro by C5a anaphylatoxin. J Immunol (1982) 1.01
Induction, maintenance and termination of immunologic unresponsiveness to bovine thyroglobulin in rabbits. J Immunol (1967) 1.01
Antibody-producing cells in rabbits injected with soluble BSA. I. Hemolytic plaque assay. J Immunol (1968) 1.00
Anaphylatoxin-mediated regulation of human and murine immune responses. Fed Proc (1984) 1.00