Tumor-promoting phorbol ester stimulates tyrosine phosphorylation in U-937 monocytes.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 345150)

Published in Proc Natl Acad Sci U S A on May 01, 1984

Authors

G Grunberger, Y Zick, S I Taylor, P Gorden

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl (1968) 60.35

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc Natl Acad Sci U S A (1980) 22.30

Protein kinase activity associated with the avian sarcoma virus src gene product. Proc Natl Acad Sci U S A (1978) 18.32

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem (1982) 16.71

Phorbol diester receptor copurifies with protein kinase C. Proc Natl Acad Sci U S A (1983) 6.25

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity. J Biol Chem (1980) 5.19

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor. Nature (1982) 4.74

Tumor-promoting phorbol esters inhibit binding of epidermal growth factor to cellular receptors. Science (1978) 3.00

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C. Proc Natl Acad Sci U S A (1983) 2.30

Phorbol ester and diacylglycerol induce protein phosphorylation at tyrosine. Nature (1984) 2.21

Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries. Proc Natl Acad Sci U S A (1980) 2.15

A tumor promoter stimulates phosphorylation on tyrosine. Biochem Biophys Res Commun (1983) 1.62

Characterization of insulin-mediated phosphorylation of the insulin receptor in a cell-free system. J Biol Chem (1983) 1.62

Vinculin, a cytoskeletal substrate of protein kinase C. J Biol Chem (1983) 1.57

Affinity alteration of insulin receptor induced by a phorbol ester. Am J Physiol (1982) 1.51

Inhibition of insulin receptor binding by phorbol esters. Eur J Biochem (1982) 1.49

Insulin stimulated phosphorylation of its own receptor. Activation of a tyrosine-specific protein kinase that is tightly associated with the receptor. J Biol Chem (1983) 1.22

The insulin receptor of a human monocyte-like cell line: characterization and function. Endocrinology (1984) 1.16

Protein kinase activity of the insulin receptor in human circulating and cultured mononuclear cells. Biochem Biophys Res Commun (1983) 0.92

The insulin-stimulated receptor kinase is a tyrosine-specific casein kinase. Eur J Biochem (1983) 0.87

Three multifunctional protein kinase systems in transmembrane control. Mol Biol Biochem Biophys (1980) 0.87

Articles by these authors

The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man. N Engl J Med (1976) 5.09

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles. Cell (1997) 4.20

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. Proc Natl Acad Sci U S A (1978) 4.03

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system. Nature (1982) 3.90

Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes. Ann Intern Med (2000) 3.44

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. Nat Genet (1996) 3.40

Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway. Proc Natl Acad Sci U S A (1987) 3.33

Use of polymerase chain reaction catalyzed by Taq DNA polymerase for site-specific mutagenesis. Gene (1989) 3.11

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes (2000) 3.01

Identification of a family of sorting nexin molecules and characterization of their association with receptors. Mol Cell Biol (1998) 2.97

Forty-eight-hour fast: the diagnostic test for insulinoma. J Clin Endocrinol Metab (2000) 2.75

Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. Mol Biol Cell (2000) 2.69

Characteristics of the human lymphocyte insulin receptor. J Biol Chem (1973) 2.61

Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine. J Biol Chem (1982) 2.58

Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. Mol Endocrinol (1997) 2.51

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J Biol Chem (1997) 2.50

125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography. J Clin Invest (1978) 2.47

Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting. J Clin Invest (1976) 2.12

Localization of insulinomas to regions of the pancreas by intra-arterial stimulation with calcium. Ann Intern Med (1995) 2.05

The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells. J Biol Chem (1990) 2.03

Benign metastasizing leiomyoma of the uterus: documentation of clinical, immunohistochemical and lectin-histochemical data of ten cases. Virchows Arch (2000) 1.97

Defect in insulin binding to receptors in obese man. Amelioration with calorie restriction. J Clin Invest (1975) 1.92

A nonsense mutation causing decreased levels of insulin receptor mRNA: detection by a simplified technique for direct sequencing of genomic DNA amplified by the polymerase chain reaction. Proc Natl Acad Sci U S A (1990) 1.90

Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: a quantitative electron microscopic study in normal and mutant human fibroblasts. J Cell Biol (1982) 1.88

Lipoatrophy revisited. Trends Endocrinol Metab (2000) 1.87

Glucose intolerance in cystic fibrosis. N Engl J Med (1969) 1.85

The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J (1992) 1.85

Efficacy of conventional pituitary irradiation in acromegaly. N Engl J Med (1970) 1.82

Localization and surgical treatment of occult insulinomas. Ann Surg (1990) 1.76

Mutational and haplotype analyses of families with familial partial lipodystrophy (Dunnigan variety) reveal recurrent missense mutations in the globular C-terminal domain of lamin A/C. Am J Hum Genet (2000) 1.76

Efficacy of leptin therapy in the different forms of human lipodystrophy. Diabetologia (2009) 1.75

Insulin resistance: a phosphorylation-based uncoupling of insulin signaling. Trends Cell Biol (2001) 1.75

Pathogenesis of congenital alkalosis with diarrhea. Implications for the physiology of normal ileal electrolyte absorption and secretion. J Clin Invest (1972) 1.73

Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio. J Biol Chem (1975) 1.73

Insulin receptors in human circulating lymphocytes: application to the study of insulin resistance in man. J Clin Endocrinol Metab (1973) 1.71

Impairment of insulin binding to the fat cell plasma membrane in the obese hyperglycemic mouse. FEBS Lett (1972) 1.71

Elevated plasma adiponectin in humans with genetically defective insulin receptors. J Clin Endocrinol Metab (2006) 1.71

"Big insulin": a new component of plasma insulin detected by immunoassay. Proc Natl Acad Sci U S A (1968) 1.67

Intracellular translocation of iodine-125-labeled insulin: direct demonstration in isolated hepatocytes. Science (1978) 1.66

Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography. J Clin Invest (1979) 1.63

Binding of 125I-human growth hormone to specific receptors in human cultured lymphocytes. Characterization of the interaction and a sensitive radioreceptor assay. J Biol Chem (1974) 1.63

Characterization of insulin-mediated phosphorylation of the insulin receptor in a cell-free system. J Biol Chem (1983) 1.62

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function. J Biol Chem (1999) 1.60

Insulinomas: localization with selective intraarterial injection of calcium. Radiology (1991) 1.58

Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. Science (1988) 1.56

Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins. J Biol Chem (2001) 1.54

Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells. Cell Regul (1991) 1.53

Affinity alteration of insulin receptor induced by a phorbol ester. Am J Physiol (1982) 1.51

Serum alpha 2-HS-glycoprotein is an inhibitor of the human insulin receptor at the tyrosine kinase level. Mol Endocrinol (1993) 1.50

Internalization of polypeptide hormones: mechanism, intracellular localization and significance. Diabetologia (1980) 1.49

Studies on the mechanism of activation of adipose tissue pyruvate dehydrogenase by insulin. J Biol Chem (1973) 1.47

Receptors for insulin, NSILA-s, and growth hormone: applications to disease states in man. Recent Prog Horm Res (1975) 1.47

Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis. J Cell Sci (2000) 1.47

Defect in phosphorylation of insulin receptors in cells from an insulin-resistant patient with normal insulin binding. Science (1984) 1.44

A gene for congenital generalized lipodystrophy maps to human chromosome 9q34. J Clin Endocrinol Metab (1999) 1.44

Immunoassay of plasma vasopressin in man. Proc Natl Acad Sci U S A (1970) 1.43

Human growth hormone radioreceptor assay using cultured human lymphocytes. Nat New Biol (1973) 1.43

The role of antireceptor antibodies in stimulating phosphorylation of the insulin receptor. J Biol Chem (1984) 1.43

An endogenous substrate for the insulin receptor-associated tyrosine kinase. J Biol Chem (1985) 1.42

Insulin receptor defect in insulin resistance: studies in the obese-hyperglycimic mouse. Biochem Biophys Res Commun (1972) 1.39

Expression of two human growth hormone genes in monkey cells infected by simian virus 40 recombinants. Proc Natl Acad Sci U S A (1981) 1.39

Proinsulin C-peptide--a consensus statement. Int J Exp Diabetes Res (2001) 1.38

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases. J Biol Chem (2001) 1.38

Acromegaly and cardiovascular disorders. A prospective study. Ann Intern Med (1974) 1.37

Diabetes and related metabolic risk factors among Arab Americans. Ann Pharmacother (1995) 1.36

Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells. Mol Cell Biol (1995) 1.36

Galectin-8 functions as a matricellular modulator of cell adhesion. J Biol Chem (2001) 1.34

Pancreatic cholera: benefical effects of treatment with streptozotocin. N Engl J Med (1975) 1.32

Morphological changes of the 3T3-L1 fibroblast plasma membrane upon differentiation to the adipocyte form. J Cell Sci (1983) 1.32

Binding and internalization of 125I-LDL in normal and mutant human fibroblasts. A quantitative autoradiographic study. Exp Cell Res (1979) 1.32

Metastatic insulin-secreting carcinoma of the pancreas: clinical course and the role of surgery. Surgery (1984) 1.30

Receptor-mediated endocytosis of insulin: role of microvilli, coated pits, and coated vesicles. Proc Natl Acad Sci U S A (1982) 1.30

Recent advances in our understanding of insulin action and insulin resistance. Diabetes Care (2001) 1.29

Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4. Proc Natl Acad Sci U S A (1994) 1.29

Glucose metabolism in perfused skeletal muscle. Pyruvate dehydrogenase activity in starvation, diabetes and exercise. Biochem J (1976) 1.29

Treatment of type B insulin resistance: a novel approach to reduce insulin receptor autoantibodies. J Clin Endocrinol Metab (2010) 1.29

NIH conference. Somatostatin and somatostatin analogue (SMS 201-995) in treatment of hormone-secreting tumors of the pituitary and gastrointestinal tract and non-neoplastic diseases of the gut. Ann Intern Med (1989) 1.28

Multisite phosphorylation of the alpha subunit of transducin by the insulin receptor kinase and protein kinase C. Proc Natl Acad Sci U S A (1986) 1.28

Surface redistribution of 125I-insulin in cultured human lymphocytes. J Cell Biol (1981) 1.27

Recurrent hematuria and focal nephritis. N Engl J Med (1967) 1.27

Intraoperative ultrasonographic localization of islet cell tumors. A prospective comparison to palpation. Ann Surg (1988) 1.27

Hypoglycemia associated with non-islet-cell tumor and insulin-like growth factors. N Engl J Med (1981) 1.26

Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells. J Biol Chem (1994) 1.26

A mutation in the insulin receptor gene that impairs transport of the receptor to the plasma membrane and causes insulin-resistant diabetes. EMBO J (1989) 1.24

Identification and characterization of SNX15, a novel sorting nexin involved in protein trafficking. J Biol Chem (2000) 1.24

Alpha2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor. Mol Cell Endocrinol (2000) 1.23

Selective inhibition of protein tyrosine phosphatase activities by H2O2 and vanadate in vitro. Biochem Biophys Res Commun (1992) 1.23

Insulin stimulates both leptin secretion and production by rat white adipose tissue. Endocrinology (1997) 1.22

Insulin stimulated phosphorylation of its own receptor. Activation of a tyrosine-specific protein kinase that is tightly associated with the receptor. J Biol Chem (1983) 1.22

Involvement of dileucine motifs in the internalization and degradation of the insulin receptor. J Biol Chem (1994) 1.21

Familial hyperproinsulinemia due to a proposed defect in conversion of proinsulin to insulin. N Engl J Med (1984) 1.20

Galectin-8. A new rat lectin, related to galectin-4. J Biol Chem (1995) 1.20

Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus. Circulation (1999) 1.19

Receptor aggregation is necessary for activation of the soluble insulin receptor kinase. J Biol Chem (1986) 1.19

A sensitive radioimmunoassay for 7S nerve growth factor antigens in serum and tissues. J Neurochem (1971) 1.19