Published in DNA on January 01, 1982
Compilation of published signal sequences. Nucleic Acids Res (1984) 11.33
Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase. EMBO J (1990) 3.62
Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements. Proc Natl Acad Sci U S A (1991) 2.16
Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine. Proc Natl Acad Sci U S A (1988) 2.12
Unusual branch point selection in processing of human growth hormone pre-mRNA. Mol Cell Biol (1988) 2.12
The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice. Mol Cell Biol (1987) 2.12
Tissue-specific expression of the human growth hormone gene is conferred in part by the binding of a specific trans-acting factor. EMBO J (1987) 2.02
Mapping enteroendocrine cell populations in transgenic mice reveals an unexpected degree of complexity in cellular differentiation within the gastrointestinal tract. J Cell Biol (1990) 1.94
Thymic tumorigenesis induced by overexpression of p56lck. Proc Natl Acad Sci U S A (1991) 1.93
Glucocorticoids enhance stability of human growth hormone mRNA. Mol Cell Biol (1987) 1.77
Pancreatic tumor pathogenesis reflects the causative genetic lesion. Proc Natl Acad Sci U S A (1991) 1.72
Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. Proc Natl Acad Sci U S A (1991) 1.60
Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones. EMBO J (1984) 1.59
Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes in transgenic mice. Mol Cell Biol (1988) 1.39
The human ubiquitin-52 amino acid fusion protein gene shares several structural features with mammalian ribosomal protein genes. Nucleic Acids Res (1991) 1.37
Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library. Mol Cell Biol (1995) 1.35
The mouse ileal lipid-binding protein gene: a model for studying axial patterning during gut morphogenesis. J Cell Biol (1994) 1.29
Expression of human basic fibroblast growth factor cDNA in baby hamster kidney-derived cells results in autonomous cell growth. J Cell Biol (1988) 1.25
Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia. Proc Natl Acad Sci U S A (1992) 1.21
Delayed thymocyte development induced by augmented expression of p56lck. J Exp Med (1991) 1.20
Isolation and characterization of the human prolactin gene. EMBO J (1984) 1.17
Adenovirus VAI-RNA regulates gene expression by controlling stability of ribosome-bound RNAs. EMBO J (1989) 1.14
DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression. Proc Natl Acad Sci U S A (1998) 1.13
Interaction of a tissue-specific factor with an essential rat growth hormone gene promoter element. Mol Cell Biol (1987) 1.08
A single element of the elastase I enhancer is sufficient to direct transcription selectively to the pancreas and gut. Mol Cell Biol (1994) 1.07
Characterization and histologic localization of human growth hormone-variant gene expression in the placenta. J Clin Invest (1989) 1.05
An evaluation of the potential to use tumor-associated antigens as targets for antitumor T cell therapy using transgenic mice expressing a retroviral tumor antigen in normal lymphoid tissues. J Exp Med (1993) 1.04
Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers. Mol Cell Biol (1987) 1.04
Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen. J Exp Med (1994) 1.03
Expression from the transferrin gene promoter in transgenic mice. Mol Cell Biol (1989) 0.99
U1 small nuclear RNAs with altered specificity can be stably expressed in mammalian cells and promote permanent changes in pre-mRNA splicing. Mol Cell Biol (1993) 0.98
Silent genes in the mouse major urinary protein gene family. Proc Natl Acad Sci U S A (1989) 0.98
The thymus leukemia antigen binds human and mouse CD8. J Exp Med (1991) 0.95
Cooperation between elements of an organ-specific transcriptional enhancer in animals. Mol Cell Biol (1995) 0.94
cDNA cloning of somatolactin, a pituitary protein related to growth hormone and prolactin. Proc Natl Acad Sci U S A (1990) 0.93
A new natural hGH variant--17.5 kd--produced by alternative splicing. An additional consensus sequence which might play a role in branchpoint selection. Nucleic Acids Res (1987) 0.92
Human growth hormone gene and the highly homologous growth hormone variant gene display different splicing patterns. J Clin Invest (1988) 0.92
Two human relaxin genes are on chromosome 9. EMBO J (1984) 0.91
Regulated expression of chimaeric genes containing the 5'-flanking regions of human growth hormone-related genes in transiently transfected rat anterior pituitary tumor cells. Nucleic Acids Res (1987) 0.90
Testis-specific expression of a metallothionein I-driven transgene correlates with undermethylation of the locus in testicular DNA. Proc Natl Acad Sci U S A (1993) 0.90
Expression of multiple proliferin genes in mouse cells. Mol Cell Biol (1986) 0.88
Glycosylated ovine prolactin. Proc Natl Acad Sci U S A (1984) 0.86
Expression of the human growth hormone variant gene in cultured fibroblasts and transgenic mice. Proc Natl Acad Sci U S A (1988) 0.85
Placental-specific expression from the mouse placental lactogen II gene promoter. Proc Natl Acad Sci U S A (1992) 0.84
Structure of a murine alpha interferon pseudogene with a repetitive R-type sequence in the 3' flanking region. Mol Cell Biol (1985) 0.82
Isolation and characterization of phosphorylated bovine prolactin. Biochem J (1993) 0.80
Genetic background affects human glial fibrillary acidic protein promoter activity. PLoS One (2013) 0.80
O-Glycosylated 24 kDa human growth hormone has a mucin-like biantennary disialylated tetrasaccharide attached at Thr-60. Proteomics (2009) 0.78
Identification of a splice-site mutation in the human growth hormone-variant gene. Am J Hum Genet (1991) 0.76
Both pituitary and placental growth hormone transcripts are expressed in human peripheral blood mononuclear cells (PBMC). Clin Exp Immunol (1997) 0.75
Expression of Growth Hormone Genes in Transgenic Mice. Banbury Rep (1) 0.75
Analysis of human growth hormone gene 5' sequences in isolated growth hormone deficiency patients. J Med Genet (1994) 0.75
A system for shotgun DNA sequencing. Nucleic Acids Res (1981) 52.99
Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. DNA (1985) 40.01
Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature (1985) 13.04
Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron (1994) 11.44
Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature (1983) 10.64
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science (1985) 9.12
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science (1995) 8.61
Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone. Nature (1977) 7.97
The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24
RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell (1991) 6.97
Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature (2000) 6.67
Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science (1992) 6.49
Biological properties of human c-Ha-ras1 genes mutated at codon 12. Nature (1984) 6.21
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene. Nature (1983) 5.90
Human leukocyte interferon produced by E. coli is biologically active. Nature (1980) 5.86
RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency. Cell (1993) 5.62
Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli. Nature (1983) 5.27
Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science (1994) 5.21
The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J Neurosci (1992) 5.02
Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature (1984) 4.99
Interaction of RNA polymerase with promoters from bacteriophage fd. Eur J Biochem (1977) 4.94
Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Science (1999) 4.56
Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. Neuron (1992) 4.53
The structure of eight distinct cloned human leukocyte interferon cDNAs. Nature (1981) 4.50
The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. J Neurosci (1992) 4.45
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature (1989) 4.45
Expression of active human factor VIII from recombinant DNA clones. Nature (1984) 4.36
Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS. Neuron (1995) 4.24
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations. Nature (1983) 4.15
A mammalian RNA editing enzyme. Nature (1996) 3.90
A family of AMPA-selective glutamate receptors. Science (1990) 3.85
Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone. Nature (1979) 3.80
Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science (1990) 3.53
Differential signal transduction by five splice variants of the PACAP receptor. Nature (1993) 3.38
Structural determinants of ion flow through recombinant glutamate receptor channels. Science (1991) 3.18
Construction and analysis of recombinant DNA for human chorionic somatomammotropin. Nature (1977) 3.13
Determinants of Ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: diversity by RNA editing. Neuron (1993) 3.08
Lutropin-choriogonadotropin receptor: an unusual member of the G protein-coupled receptor family. Science (1989) 3.03
The sequence of human serum albumin cDNA and its expression in E. coli. Nucleic Acids Res (1981) 2.97
Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA. Nature (1982) 2.96
Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis (2002) 2.92
Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice. Science (1995) 2.78
The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor. EMBO J (1984) 2.77
Functional properties of recombinant rat GABAA receptors depend upon subunit composition. Neuron (1990) 2.75
The primary structure of the Saccharomyces cerevisiae gene for 3-phosphoglycerate kinase. Nucleic Acids Res (1982) 2.67
Differences in Ca2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression. Neuron (1994) 2.67
Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. Science (1992) 2.64
RED2, a brain-specific member of the RNA-specific adenosine deaminase family. J Biol Chem (1996) 2.64
Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+. Neuron (1990) 2.60
cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc Natl Acad Sci U S A (1988) 2.59
Regulated expression of human growth hormone genes in mouse cells. Cell (1982) 2.58
A standardized nomenclature for adenosine deaminases that act on RNA. RNA (1997) 2.50
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist. Nature (1990) 2.50
The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. J Neurosci (1992) 2.48
Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones. Proc Natl Acad Sci U S A (1977) 2.47
The human pro-opiomelanocortin gene: organization, sequence, and interspersion with repetitive DNA. DNA (1982) 2.47
Patterns of polymorphism and linkage disequilibrium suggest independent origins of the human growth hormone gene cluster. Proc Natl Acad Sci U S A (1984) 2.47
Mapping and characterization of promoters in bacteriophages fd, f1 and m13. J Mol Biol (1975) 2.46
Neurosteroids act on recombinant human GABAA receptors. Neuron (1990) 2.44
A molecular determinant for submillisecond desensitization in glutamate receptors. Science (1994) 2.43
Spatial memory dissociations in mice lacking GluR1. Nat Neurosci (2002) 2.39
Two novel GABAA receptor subunits exist in distinct neuronal subpopulations. Neuron (1989) 2.38
Interaction of ion channels and receptors with PDZ domain proteins. Curr Opin Neurobiol (1997) 2.37
Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence. Proc Natl Acad Sci U S A (1985) 2.34
Saccharomyces cerevisiae contains two discrete genes coding for the alpha-factor pheromone. Nucleic Acids Res (1983) 2.34
Type I and type II GABAA-benzodiazepine receptors produced in transfected cells. Science (1989) 2.28
GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic mice. J Neurosci (1999) 2.28
Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact. EMBO J (1988) 2.26
Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell (1998) 2.21
Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-beta. Nature (1986) 2.17
The human growth hormone locus: nucleotide sequence, biology, and evolution. Genomics (1989) 2.17
The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21 to qter. Hum Genet (1981) 2.14
Gamma-aminobutyric acidA receptor alpha 5-subunit creates novel type II benzodiazepine receptor pharmacology. J Neurochem (1990) 2.09
Structural requirements for RNA editing in glutamate receptor pre-mRNAs by recombinant double-stranded RNA adenosine deaminase. J Biol Chem (1996) 2.06
A deletion truncating the gonadotropin-releasing hormone gene is responsible for hypogonadism in the hpg mouse. Science (1986) 2.06
Structure of the NMDA receptor channel M2 segment inferred from the accessibility of substituted cysteines. Neuron (1996) 2.05
GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs. EMBO J (1989) 2.05
Characterization of cDNA for precursor of human luteinizing hormone releasing hormone. Nature (1984) 1.98
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes. EMBO J (1990) 1.98
The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits. Neuron (1992) 1.97
Respiration and parturition affected by conditional overexpression of the Ca2+-activated K+ channel subunit, SK3. Science (2000) 1.97
C-Terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors. J Neurosci (2000) 1.95
A complex mosaic of high-affinity kainate receptors in rat brain. J Neurosci (1993) 1.94
Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor. Nature (1993) 1.93
Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences. Proc Natl Acad Sci U S A (1996) 1.92
Mammalian ionotropic glutamate receptors. Curr Opin Neurobiol (1993) 1.92
Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat. Proc Natl Acad Sci U S A (1986) 1.90
A single histidine in GABAA receptors is essential for benzodiazepine agonist binding. J Biol Chem (1992) 1.88
Nucleotide sequence of part of the gene for human chorionic somatomammotropin: purification of DNA complementary to predominant mRNA species. Cell (1977) 1.81
Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells. Nature (1991) 1.81
The human growth hormone gene family: structure and evolution of the chromosomal locus. Nucleic Acids Res (1983) 1.81
EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron (1999) 1.81
The dopamine D2 receptor: two molecular forms generated by alternative splicing. EMBO J (1989) 1.79
Structure and functional expression of cloned rat serotonin 5HT-2 receptor. EMBO J (1988) 1.74
Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents. Mol Pharmacol (1991) 1.73
Subtype-specific regulation of recombinant NMDA receptor-channels by protein tyrosine kinases of the src family. J Physiol (1996) 1.72
Structure of genes for human growth hormone and chorionic somatomammotropin. Proc Natl Acad Sci U S A (1979) 1.71
Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells. Science (1992) 1.69
Molecular basis for familial isolated growth hormone deficiency. Proc Natl Acad Sci U S A (1981) 1.69
In vitro deletional mutagenesis for bacterial production of the 20,000-dalton form of human pituitary growth hormone. DNA (1983) 1.67