Published in Proc Natl Acad Sci U S A on August 15, 1995
Sorting out the complexity of SR protein functions. RNA (2000) 9.25
Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana. Nucleic Acids Res (2002) 2.44
Genome-wide analysis of alternative pre-mRNA splicing in Arabidopsis thaliana based on full-length cDNA sequences. Nucleic Acids Res (2004) 2.19
Functional characterization of SR and SR-related genes in Caenorhabditis elegans. EMBO J (2000) 2.05
atSRp30, one of two SF2/ASF-like proteins from Arabidopsis thaliana, regulates splicing of specific plant genes. Genes Dev (1999) 1.82
The ASRG database: identification and survey of Arabidopsis thaliana genes involved in pre-mRNA splicing. Genome Biol (2004) 1.51
Ectopic expression of atRSZ33 reveals its function in splicing and causes pleiotropic changes in development. Mol Biol Cell (2003) 1.37
Characterization of a novel arginine/serine-rich splicing factor in Arabidopsis. Plant Cell (1996) 1.33
The serine/arginine-rich protein family in rice plays important roles in constitutive and alternative splicing of pre-mRNA. Plant Cell (2005) 1.30
Pre-mRNA splicing in plants: characterization of Ser/Arg splicing factors. Proc Natl Acad Sci U S A (1996) 1.26
The plant U1 small nuclear ribonucleoprotein particle 70K protein interacts with two novel serine/arginine-rich proteins. Plant Cell (1998) 1.23
Tissue-specific expression and dynamic organization of SR splicing factors in Arabidopsis. Mol Biol Cell (2004) 1.18
A plethora of plant serine/arginine-rich proteins: redundancy or evolution of novel gene functions? Biochem Soc Trans (2004) 1.17
A computational survey of candidate exonic splicing enhancer motifs in the model plant Arabidopsis thaliana. BMC Bioinformatics (2007) 1.13
Alternative splicing modulation by a LAMMER kinase impinges on developmental and transcriptome expression. Plant Cell (2003) 1.13
Temperature-sensitive splicing in the floral homeotic mutant apetala3-1. Plant Cell (1998) 1.10
A role for SR proteins in plant stress responses. Plant Signal Behav (2011) 1.08
Intronic and exonic sequences modulate 5' splice site selection in plant nuclei. Nucleic Acids Res (1997) 1.07
Implementing a rational and consistent nomenclature for serine/arginine-rich protein splicing factors (SR proteins) in plants. Plant Cell (2010) 1.07
Alternative splicing at NAGNAG acceptors in Arabidopsis thaliana SR and SR-related protein-coding genes. BMC Genomics (2008) 1.04
Splicing factor SF1 from Drosophila and Caenorhabditis: presence of an N-terminal RS domain and requirement for viability. RNA (1999) 1.02
An intragenic suppressor of the Arabidopsis floral organ identity mutant apetala3-1 functions by suppressing defects in splicing. Plant Cell (1998) 1.01
PRH75, a new nucleus-localized member of the DEAD-box protein family from higher plants. Mol Cell Biol (1997) 1.00
Transportin-SR is required for proper splicing of resistance genes and plant immunity. PLoS Genet (2011) 0.97
Retrotransposon insertion into the maize waxy gene results in tissue-specific RNA processing. Plant Cell (1997) 0.96
Molecular characterization and phylogeny of U2AF35 homologs in plants. Plant Physiol (2006) 0.91
Determinants of plant U12-dependent intron splicing efficiency. Plant Cell (2004) 0.89
Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process. Biomolecules (2015) 0.80
NMD mechanism and the functions of Upf proteins in plant. Plant Cell Rep (2015) 0.77
A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res (1984) 181.98
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature (1990) 8.79
SR proteins: a conserved family of pre-mRNA splicing factors. Genes Dev (1992) 8.60
Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell (1993) 8.07
Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell (1992) 7.90
Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors. Nature (1994) 6.97
Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U1 70K, and Drosophila splicing regulators. Cell (1991) 6.50
A role for exon sequences and splice-site proximity in splice-site selection. Cell (1986) 6.41
A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell (1990) 5.92
Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell (1991) 5.72
The essential pre-mRNA splicing factor SF2 influences 5' splice site selection by activating proximal sites. Cell (1990) 5.67
Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells. Genes Dev (1990) 5.36
A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Nature (1994) 5.01
A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA. Cell (1993) 4.82
Specific commitment of different pre-mRNAs to splicing by single SR proteins. Nature (1993) 4.74
The AU-rich sequences present in the introns of plant nuclear pre-mRNAs are required for splicing. Cell (1989) 4.53
Substrates for p34cdc2: in vivo veritas? Cell (1990) 4.34
SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex. Mol Cell Biol (1994) 4.25
General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection. Proc Natl Acad Sci U S A (1992) 3.97
Multiplex DNA sequencing. Science (1988) 3.70
Isolation of a complementary DNA that encodes the mammalian splicing factor SC35. Science (1992) 3.52
Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains. EMBO J (1993) 3.51
Different effects of intron nucleotide composition and secondary structure on pre-mRNA splicing in monocot and dicot plants. EMBO J (1991) 3.12
Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF. EMBO J (1993) 3.11
A functional association between the 5' and 3' splice site is established in the earliest prespliceosome complex (E) in mammals. Genes Dev (1993) 2.83
Functional domains of the human splicing factor ASF/SF2. EMBO J (1993) 2.83
Nuclear pre-mRNA processing in plants: distinct modes of 3'-splice-site selection in plants and animals. Mol Cell Biol (1988) 2.32
SPKK, a new nucleic acid-binding unit of protein found in histone. EMBO J (1989) 2.31
Nuclear pre-mRNA introns: analysis and comparison of intron sequences from Tetrahymena thermophila and other eukaryotes. Nucleic Acids Res (1990) 2.25
Human SR proteins and isolation of a cDNA encoding SRp75. Mol Cell Biol (1993) 2.04
Accurate in vitro splicing of two pre-mRNA plant introns in a HeLa cell nuclear extract. EMBO J (1986) 1.80
3' splice site selection in dicot plant nuclei is position dependent. Mol Cell Biol (1993) 1.49
Histone-DNA interactions and their modulation by phosphorylation of -Ser-Pro-X-Lys/Arg- motifs. EMBO J (1991) 1.40
Splicing of plant pre-mRNAs in animal systems and vice versa. Gene (1987) 1.29
Factors affecting authentic 5' splice site selection in plant nuclei. Mol Cell Biol (1993) 1.26
Alternative branch points are selected during splicing of a yeast pre-mRNA in mammalian and yeast extracts. Proc Natl Acad Sci U S A (1986) 1.25
In vitro processing of a plant pre-mRNA in a HeLa cell nuclear extract. Nucleic Acids Res (1986) 1.18
AU-rich intronic elements affect pre-mRNA 5' splice site selection in Drosophila melanogaster. Mol Cell Biol (1993) 1.16
Plant small nuclear RNAs. V. U4 RNA is present in broad bean plants in the form of sequence variants and is base-paired with U6 RNA. Nucleic Acids Res (1988) 1.09
Developmental expression of plant snRNAs. Nucleic Acids Res (1991) 0.94
Molecular comparison of monocot and dicot U1 and U2 snRNAs. Plant J (1992) 0.81
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
Nucleotide sequence of the rightward operator of phage lambda. Proc Natl Acad Sci U S A (1975) 56.75
The isolation of structural genes from libraries of eucaryotic DNA. Cell (1978) 37.13
High resolution two-dimensional electrophoresis of basic as well as acidic proteins. Cell (1977) 30.04
Analysis of endonuclease R-EcoRI fragments of DNA from lambdoid bacteriophages and other viruses by agarose-gel electrophoresis. J Virol (1974) 23.54
The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA. Cell (1978) 22.88
Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis. Biochemistry (1975) 22.00
The structure and evolution of the human beta-globin gene family. Cell (1980) 21.24
Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell (1979) 21.15
Identification of two distinct regulatory regions adjacent to the human beta-interferon gene. Cell (1983) 17.60
Rat insulin genes: construction of plasmids containing the coding sequences. Science (1977) 17.05
DNA nucleotide sequence restricted by the RI endonuclease. Proc Natl Acad Sci U S A (1972) 15.71
Regulation of inducible and tissue-specific gene expression. Science (1987) 15.04
Amplification and characterization of a beta-globin gene synthesized in vitro. Cell (1976) 14.99
Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro. Cell (1984) 12.30
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell (1994) 11.62
Specificity of substrate recognition by the EcoRI restriction endonuclease. Proc Natl Acad Sci U S A (1975) 11.07
The primary structure of rabbit beta-globin mRNA as determined from cloned DNA. Cell (1977) 11.05
Detection and localization of single base changes by denaturing gradient gel electrophoresis. Methods Enzymol (1987) 10.90
Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o. Proc Natl Acad Sci U S A (1977) 10.64
Replication and transcription of eukaryotic DNA in Escherichia coli. Proc Natl Acad Sci U S A (1974) 10.51
Identification of DNA sequences required for transcription of the human alpha 1-globin gene in a new SV40 host-vector system. Cell (1981) 9.81
Human beta-globin pre-mRNA synthesized in vitro is accurately spliced in Xenopus oocyte nuclei. Cell (1983) 9.77
Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro. Cell (1984) 9.13
The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions. Cell (1980) 9.13
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature (1990) 8.79
Nopaline synthase: transcript mapping and DNA sequence. J Mol Appl Genet (1982) 8.73
Transcriptional activation: a complex puzzle with few easy pieces. Cell (1994) 8.63
Isolation of the Arabidopsis ABI3 gene by positional cloning. Plant Cell (1992) 8.36
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing. Nature (1987) 8.28
The nucleotide sequence of the human beta-globin gene. Cell (1980) 8.11
Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell (1993) 8.07
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Nature (1999) 8.04
Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone. Nature (1977) 7.97
Molecular cloning and characterization of the human beta-like globin gene cluster. Cell (1980) 7.77
Molecular cloning and characterization of avian sarcoma virus circular DNA molecules. J Virol (1980) 7.37
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway. Genes Dev (1995) 7.36
NF-kappa B: a lesson in family values. Cell (1995) 7.33
Transcriptional activation of cloned human beta-globin genes by viral immediate-early gene products. Cell (1983) 7.22
Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell (1995) 7.17
Human growth hormone as a reporter gene in regulation studies employing transient gene expression. Mol Cell Biol (1986) 7.11
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell (1998) 7.01
Ligation of EcoRI endonuclease-generated DNA fragments into linear and circular structures. J Mol Biol (1975) 6.95
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro. Cell (1985) 6.85
Structure of the lambda operators. Nature (1973) 6.66
Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis. Nucleic Acids Res (1985) 6.52
Specific transcription and RNA splicing defects in five cloned beta-thalassaemia genes. Nature (1983) 6.48
A role for exon sequences and splice-site proximity in splice-site selection. Cell (1986) 6.41
Fine structure genetic analysis of a beta-globin promoter. Science (1986) 6.36
Detection of single base substitutions by ribonuclease cleavage at mismatches in RNA:DNA duplexes. Science (1985) 6.35
Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter. Cell (2000) 6.32
Sequence of a repressor-binding site in the DNA of bacteriophage lamda. Nature (1974) 6.22
Nucleotide sequence of the gene coding for the major protein of hepatitis B virus surface antigen. Nature (1979) 6.10
Isolation and characterization of a cloned rat insulin gene. Cell (1979) 6.05
Detection of single base substitutions in total genomic DNA. Nature (1985) 5.99
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell (1996) 5.91
DNA substrate site for the EcoRII restriction endonuclease and modification methylase. Nat New Biol (1973) 5.90
The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta gene. Cell (1992) 5.85
Sequence of the human insulin gene. Nature (1980) 5.76
The human beta-interferon gene enhancer is under negative control. Cell (1986) 5.61
Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J (1995) 5.59
The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell (1989) 5.50
Synthetic lac operator DNA is functional in vivo. Nature (1976) 5.36
Enzymatic in vitro synthesis of globin genes. Cell (1976) 5.31
Intron sequences involved in lariat formation during pre-mRNA splicing. Cell (1985) 5.30
Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product. Nature (1980) 5.22
Effects of ionizing radiation on a plant genome: analysis of two Arabidopsis transparent testa mutations. Plant Cell (1992) 5.16
Multiple repressor binding at the operators in bacteriophage lambda. Proc Natl Acad Sci U S A (1973) 5.15
Nucleotide sequences at the cleavage sites of two restriction endonucleases from Hemophilus parainfluenzae. Biochem Biophys Res Commun (1974) 5.14
Differences in human alpha- and beta-globin gene expression in mouse erythroleukemia cells: the role of intragenic sequences. Cell (1984) 5.12
The Arabidopsis abscisic acid response locus ABI4 encodes an APETALA 2 domain protein. Plant Cell (1998) 4.92
Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis. Plant J (1995) 4.87
Isolation of the Arabidopsis GA4 locus. Plant Cell (1995) 4.86
A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA. Cell (1993) 4.82
NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev (2001) 4.70
Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells. Proc Natl Acad Sci U S A (1982) 4.69
Human beta-interferon gene expression is regulated by an inducible enhancer element. Cell (1985) 4.68
The molecular genetics of human hemoglobins. Annu Rev Genet (1980) 4.67
Structure and in vitro transcription of human globin genes. Science (1980) 4.65
A cyclic AMP- and phorbol ester-inducible DNA element. Nature (1986) 4.60
Physical identity of the SV40 deoxyribonucleic acid sequence recognized by the Eco RI restriction endonuclease and modification methylase. Biochemistry (1974) 4.58
Molecular cloning and sequence analysis of adult chicken betal globin cDNA. Nucleic Acids Res (1979) 4.49
cis and trans activation of globin gene transcription in transient assays. Proc Natl Acad Sci U S A (1983) 4.41
Activation of the human beta-interferon gene requires an interferon-inducible factor. Mol Cell Biol (1986) 4.38
Associations between distinct pre-mRNA splicing components and the cell nucleus. EMBO J (1991) 4.38
Tumor DNA structure in plant cells transformed by A. tumefaciens. Science (1980) 4.36
Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda. Cell (1975) 4.28
A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell (1999) 4.25
Tuberculosis as a manifestation of the acquired immunodeficiency syndrome (AIDS). JAMA (1986) 4.25
Control elements in the DNA of bacteriophage lambda. Cold Spring Harb Symp Quant Biol (1974) 4.23
A single-base change at a splice site in a beta 0-thalassemic gene causes abnormal RNA splicing. Cell (1982) 4.22
Restriction and modification of a self-complementary octanucleotide containing the EcoRI substrate. J Mol Biol (1975) 4.21
Characterisation of deletions which affect the expression of fetal globin genes in man. Nature (1979) 4.18
Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination. Proc Natl Acad Sci U S A (1995) 4.16
The structure of a human alpha-globin pseudogene and its relationship to alpha-globin gene duplication. Cell (1980) 4.15
The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene. Cell (1982) 4.13
Human growth hormone DNA sequence and mRNA structure: possible alternative splicing. Nucleic Acids Res (1981) 4.03
Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell (1993) 4.01
General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection. Proc Natl Acad Sci U S A (1992) 3.97
A general method for saturation mutagenesis of cloned DNA fragments. Science (1985) 3.94