Published in Proc Natl Acad Sci U S A on October 11, 1994
Telomere diseases. N Engl J Med (2009) 5.68
Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats. Proc Natl Acad Sci U S A (1997) 4.88
Age-associated characteristics of murine hematopoietic stem cells. J Exp Med (2000) 4.65
A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J Exp Med (2004) 4.37
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med (1999) 4.27
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci U S A (2003) 4.09
The telomere syndromes. Nat Rev Genet (2012) 4.01
Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita. Blood (2007) 3.86
Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci U S A (1995) 3.79
Human telomerase contains evolutionarily conserved catalytic and structural subunits. Genes Dev (1997) 3.47
Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J Clin Invest (2000) 2.96
Human naive and memory T lymphocytes differ in telomeric length and replicative potential. Proc Natl Acad Sci U S A (1995) 2.77
Telomere length in early life predicts lifespan. Proc Natl Acad Sci U S A (2012) 2.74
Aging and replicative senescence have related effects on human stem and progenitor cells. PLoS One (2009) 2.62
Regulated expression of telomerase activity in human T lymphocyte development and activation. J Exp Med (1996) 2.60
Syndromes of telomere shortening. Annu Rev Genomics Hum Genet (2009) 2.60
Human diseases of telomerase dysfunction: insights into tissue aging. Nucleic Acids Res (2007) 2.34
Telomere length and heredity: Indications of paternal inheritance. Proc Natl Acad Sci U S A (2005) 2.10
Telomere length in epidemiology: a biomarker of aging, age-related disease, both, or neither? Epidemiol Rev (2013) 2.05
Telomere lengthening and telomerase activation during human B cell differentiation. Proc Natl Acad Sci U S A (1997) 1.93
Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice. Proc Natl Acad Sci U S A (2004) 1.83
Telomeres shorten more slowly in long-lived birds and mammals than in short-lived ones. Proc Biol Sci (2003) 1.81
Telomere length regulation in mice is linked to a novel chromosome locus. Proc Natl Acad Sci U S A (1998) 1.78
The power of exercise: buffering the effect of chronic stress on telomere length. PLoS One (2010) 1.78
Mechanisms that regulate stem cell aging and life span. Cell Stem Cell (2013) 1.73
Engineered telomere degradation models dyskeratosis congenita. Genes Dev (2008) 1.72
Telomerase regulation during entry into the cell cycle in normal human T cells. Mol Biol Cell (1996) 1.71
Telomere loss in relation to age and early environment in long-lived birds. Proc Biol Sci (2004) 1.66
SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity. Mol Biol Cell (2008) 1.66
Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells. EMBO J (2003) 1.64
Dyskeratosis congenita, stem cells and telomeres. Biochim Biophys Acta (2009) 1.62
Telomeres and age-related disease: how telomere biology informs clinical paradigms. J Clin Invest (2013) 1.58
The replication rate of human hematopoietic stem cells in vivo. Blood (2011) 1.58
In vivo telomere dynamics of human hematopoietic stem cells. Proc Natl Acad Sci U S A (1997) 1.58
Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes. PLoS Genet (2012) 1.57
Telomeres are shorter in myocardial infarction patients compared to healthy subjects: correlation with environmental risk factors. J Mol Med (Berl) (2010) 1.51
Telomere length, telomerase activity, and replicative potential in HIV infection: analysis of CD4+ and CD8+ T cells from HIV-discordant monozygotic twins. J Exp Med (1997) 1.50
Telomere biology in healthy aging and disease. Pflugers Arch (2009) 1.41
Telomere length regulation during postnatal development and ageing in Mus spretus. Nucleic Acids Res (1997) 1.41
Integrating physiological regulation with stem cell and tissue homeostasis. Neuron (2011) 1.41
Changes in primary lymphoid organs with aging. Semin Immunol (2012) 1.40
Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert. Proc Natl Acad Sci U S A (2002) 1.38
Dyskeratosis congenita as a disorder of telomere maintenance. Mutat Res (2011) 1.35
Quantifying T lymphocyte turnover. J Theor Biol (2013) 1.35
Telomeres, stem cells, and hematology. Blood (2008) 1.34
Impact of genomic damage and ageing on stem cell function. Nat Cell Biol (2014) 1.33
Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells. Mol Cell Biol (2005) 1.31
A natural product telomerase activator as part of a health maintenance program. Rejuvenation Res (2010) 1.30
Telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic stem cells. J Exp Med (2001) 1.30
Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation. Br J Cancer (2001) 1.28
Asymmetric cell divisions sustain long-term hematopoiesis from single-sorted human fetal liver cells. J Exp Med (1998) 1.27
How unfinished business from S-phase affects mitosis and beyond. EMBO J (2013) 1.26
The peripheral generation of CD4+ CD25+ regulatory T cells. Immunology (2003) 1.25
Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids. EMBO J (1996) 1.23
In situ analysis of changes in telomere size during replicative aging and cell transformation. J Cell Biol (1996) 1.23
The dual impact of HIV-1 infection and aging on naïve CD4 T-cells: additive and distinct patterns of impairment. PLoS One (2011) 1.23
Telomere shortening is an in vivo marker of myocyte replication and aging. Am J Pathol (2000) 1.21
Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts. Aging Cell (2007) 1.20
Compartmental architecture and dynamics of hematopoiesis. PLoS One (2007) 1.19
Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway. Mol Biol Cell (2005) 1.17
Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy. Cell Death Dis (2013) 1.16
Stem cells and aging in the hematopoietic system. Mech Ageing Dev (2008) 1.16
Differences in disease severity but similar telomere lengths in genetic subgroups of patients with telomerase and shelterin mutations. PLoS One (2011) 1.16
Therapy-related myelodysplasia and acute myeloid leukemia. Semin Oncol (2013) 1.15
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer. Cell Stem Cell (2015) 1.11
Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart. Proc Natl Acad Sci U S A (2001) 1.10
Telomere shortening and ageing. Z Gerontol Geriatr (2007) 1.10
Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy. Transl Res (2013) 1.08
Dissociation of telomerase activity and telomere length maintenance in primitive human hematopoietic cells. Proc Natl Acad Sci U S A (2005) 1.07
The association of telomere length with paternal history of premature myocardial infarction in the European Atherosclerosis Research Study II. J Mol Med (Berl) (2008) 1.06
Neutral evolution in paroxysmal nocturnal hemoglobinuria. Proc Natl Acad Sci U S A (2008) 1.05
Telomere lengths and telomerase activity in dog tissues: a potential model system to study human telomere and telomerase biology. Neoplasia (2001) 1.05
Association of leukocyte telomere length with echocardiographic left ventricular mass: the Framingham heart study. Circulation (2009) 1.04
Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection? Aging (Albany NY) (2011) 1.04
Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita. Blood (2008) 1.04
Rheumatoid arthritis: a role for immunosenescence? J Am Geriatr Soc (2010) 1.04
Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment. Mol Cell Biol (1999) 1.02
Modeling of replicative senescence in hematopoietic development. Aging (Albany NY) (2009) 0.99
Dynamics of mutant cells in hierarchical organized tissues. PLoS Comput Biol (2011) 0.99
Mankind's first natural stem cell transplant. J Cell Mol Med (2010) 0.99
Regulation of senescence in cancer and aging. J Aging Res (2011) 0.98
Telomerase activity in melanocytic lesions: A potential marker of tumor biology. Am J Pathol (2000) 0.97
Red blood cell size is inversely associated with leukocyte telomere length in a large multi-ethnic population. PLoS One (2012) 0.97
Regulation of telomerase activity by alternate splicing of human telomerase reverse transcriptase mRNA in a subset of neuroblastomas. Am J Pathol (2001) 0.97
Caspase-dependent apoptosis induced by telomere cleavage and TRF2 loss. Neoplasia (2001) 0.96
RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1alpha as critical for telomerase function in murine embryonic stem cells. Proc Natl Acad Sci U S A (2010) 0.96
Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells. Exp Hematol (2007) 0.95
Making the most of a little: dosage effects in eukaryotic telomere length maintenance. Chromosome Res (2005) 0.95
Probing the mitotic history and developmental stage of hematopoietic cells using single telomere length analysis (STELA). Blood (2009) 0.95
Aging stem cells, latexin, and longevity. Exp Cell Res (2008) 0.94
Telomerase deficiency does not alter bleomycin-induced fibrosis in mice. Exp Lung Res (2012) 0.93
The short and long telomere syndromes: paired paradigms for molecular medicine. Curr Opin Genet Dev (2015) 0.93
Predicting 5-fluorouracil toxicity in colorectal cancer patients from peripheral blood cell telomere length: a multivariate analysis. Br J Cancer (2012) 0.92
Toll-like receptor triggering in cord blood mesenchymal stem cells. J Cell Mol Med (2009) 0.92
The molecular genetics of the telomere biology disorders. RNA Biol (2015) 0.91
Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1997) 0.90
Essential roles for Pot1b in HSC self-renewal and survival. Blood (2011) 0.89
Innate regeneration in the aging heart: healing from within. Mayo Clin Proc (2013) 0.89
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell (1985) 24.17
Telomeres shorten during ageing of human fibroblasts. Nature (1990) 23.97
Structure and function of telomeres. Nature (1991) 14.82
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc Natl Acad Sci U S A (1988) 11.81
Telomere reduction in human colorectal carcinoma and with ageing. Nature (1990) 11.24
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J (1992) 10.97
Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A (1992) 10.19
A mutant with a defect in telomere elongation leads to senescence in yeast. Cell (1989) 8.69
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell (1989) 8.68
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. J Theor Biol (1973) 7.28
Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell (1993) 6.83
Telomere loss: mitotic clock or genetic time bomb? Mutat Res (1992) 6.50
Developmental potential and dynamic behavior of hematopoietic stem cells. Cell (1986) 5.98
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet (1993) 4.78
Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J Immunol (1984) 4.55
The identification in adult bone marrow of pluripotent and restricted stem cells of the myeloid and lymphoid systems. J Exp Med (1977) 4.44
Isolation of a candidate human hematopoietic stem-cell population. Proc Natl Acad Sci U S A (1992) 4.28
Telomerase activity in human ovarian carcinoma. Proc Natl Acad Sci U S A (1994) 3.86
In vivo loss of telomeric repeats with age in humans. Mutat Res (1991) 3.18
Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells. Blood (1991) 3.12
Sugar and disease. Nature (1972) 2.89
Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure. J Exp Med (1982) 2.77
Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults. Proc Natl Acad Sci U S A (1992) 2.41
Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow. J Exp Med (1992) 2.33
[Principle of marginotomy in template synthesis of polynucleotides]. Dokl Akad Nauk SSSR (1971) 2.26
Serial depletion and regeneration of the murine hematopoietic system. Implications for hematopoietic organization and the study of cellular aging. J Exp Med (1982) 2.16
Activation of telomerase in a human tumor. Proc Natl Acad Sci U S A (1994) 2.11
Expression of Thy-1 on human hematopoietic progenitor cells. J Exp Med (1993) 2.09
Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells. EMBO J (1987) 2.02
Life span of multipotential hematopoietic stem cells in vivo. J Exp Med (1990) 1.82
Clonal contributions of small numbers of retrovirally marked hematopoietic stem cells engrafted in unirradiated neonatal W/Wv mice. Proc Natl Acad Sci U S A (1989) 1.81
Organization of haemopoietic stem cells: the generation-age hypothesis. Cell Tissue Kinet (1979) 1.71
Hematopoietic stem cell depletion by restorative growth factor regimens during repeated high-dose cyclophosphamide therapy. Blood (1992) 1.66
Ontogeny-related changes in proliferative potential of human hematopoietic cells. J Exp Med (1993) 1.64
Monoclonal derivation of mouse myeloid and lymphoid lineages from totipotent hematopoietic stem cells experimentally engrafted in fetal hosts. Proc Natl Acad Sci U S A (1984) 1.47
Development of adult bone marrow stem cells in H-2-compatible and -incompatible mouse fetuses. J Exp Med (1984) 1.46
Expansion in vitro of retrovirally marked totipotent hematopoietic stem cells. Blood (1990) 1.27
Recipient preparation for bone marrow transplantation. I. Efficacy of total-body irradiation and busulfan. Transplantation (1988) 1.21
Cytokine-induced selective expansion and maturation of erythroid versus myeloid progenitors from purified cord blood precursor cells. Blood (1993) 1.10
Significant telomere shortening in childhood leukemia. Cancer Genet Cytogenet (1992) 1.05
Aging, healing, and the metabolism of telomeres. Am J Hum Genet (1993) 0.86
Specific association of human telomerase activity with immortal cells and cancer. Science (1994) 28.20
Extension of life-span by introduction of telomerase into normal human cells. Science (1998) 20.48
Analysis of E. coli promoter sequences. Nucleic Acids Res (1987) 14.12
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell (1997) 13.34
Telomerase catalytic subunit homologs from fission yeast and human. Science (1997) 12.35
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J (1992) 10.97
Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A (1992) 10.19
The RNA component of human telomerase. Science (1995) 9.86
Production of hybridoma growth factor by human monocytes. Eur J Immunol (1987) 7.99
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat Genet (1997) 6.69
Telomere end-replication problem and cell aging. J Mol Biol (1992) 5.37
Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen. Mol Cell Biol (1989) 5.01
Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats. Proc Natl Acad Sci U S A (1997) 4.88
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet (1993) 4.78
Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat Biotechnol (1998) 4.68
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med (1999) 4.27
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proc Natl Acad Sci U S A (1998) 4.11
Telomerase activity in human ovarian carcinoma. Proc Natl Acad Sci U S A (1994) 3.86
Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev (1995) 3.81
Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy. Proc Natl Acad Sci U S A (1990) 3.43
Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells. Blood (1991) 3.12
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc Natl Acad Sci U S A (1994) 3.08
Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS (1996) 2.95
Short telomeres on human chromosome 17p. Nat Genet (1998) 2.81
Telomerase activity in normal leukocytes and in hematologic malignancies. Blood (1995) 2.71
Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia. Mol Cell Biol (1997) 2.61
Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc Natl Acad Sci U S A (1990) 2.59
Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. J Virol (1994) 2.57
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation. Oncogene (1998) 2.49
Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro. Blood (1989) 2.44
Telomere length and replicative aging in human vascular tissues. Proc Natl Acad Sci U S A (1995) 2.40
The telomere hypothesis of cellular aging. Exp Gerontol (1993) 2.39
Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo. Blood (1997) 2.33
Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow. J Exp Med (1992) 2.33
Extension of cell life-span and telomere length in animals cloned from senescent somatic cells. Science (2000) 2.25
Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells. Curr Biol (2001) 2.21
Evidence for a critical telomere length in senescent human fibroblasts. Exp Cell Res (1995) 2.16
Telomere shortening is associated with cell division in vitro and in vivo. Exp Cell Res (1995) 2.11
Expression of Thy-1 on human hematopoietic progenitor cells. J Exp Med (1993) 2.09
Telomere length measurements using digital fluorescence microscopy. Cytometry (1999) 2.03
Molecular cloning and expression of the major protein kinase C substrate of platelets. Nature (1988) 2.00
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells (1996) 1.97
The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo. Curr Biol (2000) 1.97
Telomere length in leukocyte subpopulations of patients with aplastic anemia. Blood (2001) 1.89
Isolation in a single step of a highly enriched murine hematopoietic stem cell population with competitive long-term repopulating ability. Blood (1989) 1.84
A growth-factor dependent B-cell hybridoma. Curr Top Microbiol Immunol (1986) 1.79
Telomere length regulation in mice is linked to a novel chromosome locus. Proc Natl Acad Sci U S A (1998) 1.78
Telomerase activity in candidate stem cells from fetal liver and adult bone marrow. Blood (1998) 1.77
Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential. Blood (2001) 1.71
Ontogeny-related changes in proliferative potential of human hematopoietic cells. J Exp Med (1993) 1.64
The human hematopoietic stem cell in vitro and in vivo. Blood Cells (1992) 1.58
Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability. Nat Genet (1999) 1.56
Lineage commitment in human hemopoiesis involves asymmetric cell division of multipotent progenitors and does not appear to be influenced by cytokines. J Cell Physiol (1993) 1.53
Learning the evolutionarily stable strategy. J Theor Biol (1981) 1.52
Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot study. Blood (1994) 1.51
The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts. Blood (1996) 1.45
Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. Blood (1991) 1.44
A comparison of long-term repopulating hematopoietic stem cells in fetal liver and adult bone marrow from the mouse. Exp Hematol (1996) 1.42
Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA. Mol Cell Biol (2000) 1.42
Telomerase activity in normal and malignant murine tissues. Oncogene (1995) 1.34
Immunological study of in vitro maturation of human megakaryocytes. Br J Haematol (1984) 1.32
Accumulation of short telomeres in human fibroblasts prior to replicative senescence. Exp Cell Res (2000) 1.30
Retrovirus-mediated gene transfer to purified hemopoietic stem cells with long-term lympho-myelopoietic repopulating ability. Proc Natl Acad Sci U S A (1989) 1.29
Telomerase expression restores dermal integrity to in vitro-aged fibroblasts in a reconstituted skin model. Exp Cell Res (2000) 1.27
Asymmetric cell divisions sustain long-term hematopoiesis from single-sorted human fetal liver cells. J Exp Med (1998) 1.27
Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation. Blood (2001) 1.26
Biology of human umbilical cord blood-derived hematopoietic stem/progenitor cells. Stem Cells (1998) 1.26
Monoclonal antibodies against human platelet glycoprotein IIIa. Br J Haematol (1983) 1.25
Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells in vivo. Blood (1997) 1.24
Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells. Exp Cell Res (2008) 1.24
Flow cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients. Blood (1991) 1.23
Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1). J Clin Invest (1992) 1.21
DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression. Mol Cell Biol (2001) 1.20
Replicative senescence and cell immortality: the role of telomeres and telomerase. Proc Soc Exp Biol Med (1997) 1.20
Immunoperoxidase procedures to detect monoclonal antibodies against cell surface antigens. Quantitation of binding and staining of individual cells. J Immunol Methods (1980) 1.19
Separation of functionally distinct subpopulations of primitive human hematopoietic cells using rhodamine-123. Exp Hematol (1991) 1.17
Studies of W mutant mice provide evidence for alternate mechanisms capable of activating hematopoietic stem cells. Exp Hematol (1996) 1.16
Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks. DNA Repair (Amst) (2008) 1.16
Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood. Blood (1994) 1.14
Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. Hum Mol Genet (2001) 1.11
Age-related decline in proliferative potential of purified stem cell candidates. Blood Cells (1994) 1.11
Effect of vitamin E on lifespan and reproduction in Caenorhabditis elegans. Mech Ageing Dev (1988) 1.10