Published in J Biol Chem on September 15, 1993
A component of the chloroplastic protein import apparatus is targeted to the outer envelope membrane via a novel pathway. EMBO J (1995) 2.20
Mas37p, a novel receptor subunit for protein import into mitochondria. J Cell Biol (1995) 1.89
Characterization of signal that directs C-tail-anchored proteins to mammalian mitochondrial outer membrane. Mol Biol Cell (2002) 1.76
Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol (1998) 1.71
Biogenesis of Tom40, core component of the TOM complex of mitochondria. J Cell Biol (1999) 1.53
The mitochondrial outer membrane protein Mas22p is essential for protein import and viability of yeast. Proc Natl Acad Sci U S A (1994) 1.52
A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria. J Cell Biol (1994) 1.25
Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway. Mol Biol Cell (1999) 1.25
VDAC and the bacterial porin PorB of Neisseria gonorrhoeae share mitochondrial import pathways. EMBO J (2002) 1.06
Structural requirements of Tom40 for assembly into preexisting TOM complexes of mitochondria. Mol Biol Cell (2001) 0.99
Yeast mitochondria lacking the phosphate carrier/p32 are blocked in phosphate transport but can import preproteins after regeneration of a membrane potential. Mol Cell Biol (1996) 0.87
Function of cytosolic chaperones in Tom70-mediated mitochondrial import. Protein Pept Lett (2011) 0.86
The role of Djp1 in import of the mitochondrial protein Mim1 demonstrates specificity between a cochaperone and its substrate protein. Mol Cell Biol (2013) 0.81
Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins. Nature (1990) 5.12
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell (1994) 4.47
Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins [see comment]. Nature (1998) 3.77
Mitochondrial protein import. Biochim Biophys Acta (1989) 3.66
Mitochondrial Hsp70/MIM44 complex facilitates protein import. Nature (1994) 3.08
A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23. Nat Struct Biol (2001) 3.06
Tom5 functionally links mitochondrial preprotein receptors to the general import pore. Nature (1997) 2.88
A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins. J Cell Biol (1993) 2.61
Mitochondrial protein import: nucleoside triphosphates are involved in conferring import-competence to precursors. Cell (1987) 2.61
Multistep assembly of the protein import channel of the mitochondrial outer membrane. Nat Struct Biol (2001) 2.46
Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. One gene codes for both the cytosolic and mitochondrial forms. J Biol Chem (1988) 2.43
Transport of F1-ATPase subunit beta into mitochondria depends on both a membrane potential and nucleoside triphosphates. FEBS Lett (1986) 2.33
The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44. EMBO J (1997) 2.28
Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44. J Cell Biol (1994) 2.28
Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem (2000) 2.26
Transport of proteins into mitochondria: a potassium diffusion potential is able to drive the import of ADP/ATP carrier. EMBO J (1985) 2.19
MOM19, an import receptor for mitochondrial precursor proteins. Cell (1989) 2.18
Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequences. J Biol Chem (1991) 2.17
Assaying protein import into mitochondria. Methods Cell Biol (2001) 2.04
Distinct steps in the import of ADP/ATP carrier into mitochondria. J Biol Chem (1987) 2.02
A mitochondrial import receptor for the ADP/ATP carrier. Cell (1990) 1.95
How do polypeptides cross the mitochondrial membranes? Cell (1990) 1.91
The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70. Cell (1999) 1.91
Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins. Nature (1990) 1.90
Analysis of mitochondrial protein import using translocation intermediates and specific antibodies. Methods Cell Biol (1991) 1.81
Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix. J Cell Biol (1993) 1.73
Import of ADP/ATP carrier into mitochondria: two receptors act in parallel. J Cell Biol (1990) 1.72
Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol (1998) 1.71
The mitochondrial receptor complex: a central role of MOM22 in mediating preprotein transfer from receptors to the general insertion pore. Cell (1993) 1.67
Differential recognition of preproteins by the purified cytosolic domains of the mitochondrial import receptors Tom20, Tom22, and Tom70. J Biol Chem (1997) 1.66
Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex. J Cell Biol (2001) 1.65
Protein unfolding by mitochondria. The Hsp70 import motor. EMBO Rep (2000) 1.64
Nitric oxide acts directly in the presynaptic neuron to produce long-term potentiation in cultured hippocampal neurons. Cell (1996) 1.63
The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system. Cell (1995) 1.63
Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase. Cell (1996) 1.61
Polypeptides traverse the mitochondrial envelope in an extended state. FEBS Lett (1990) 1.60
The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria. EMBO J (2001) 1.60
Mapping of the protein import machinery in the mitochondrial outer membrane by crosslinking of translocation intermediates. Nature (1992) 1.56
Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase. Nature (1999) 1.56
Partner proteins determine multiple functions of Hsp70. Trends Cell Biol (1995) 1.55
Protein import channel of the outer mitochondrial membrane: a highly stable Tom40-Tom22 core structure differentially interacts with preproteins, small tom proteins, and import receptors. Mol Cell Biol (2001) 1.53
Functional staging of ADP/ATP carrier translocation across the outer mitochondrial membrane. J Biol Chem (1999) 1.52
Import pathways of precursor proteins into mitochondria: multiple receptor sites are followed by a common membrane insertion site. J Cell Biol (1988) 1.52
Tom7 modulates the dynamics of the mitochondrial outer membrane translocase and plays a pathway-related role in protein import. EMBO J (1996) 1.51
Distribution of binding sequences for the mitochondrial import receptors Tom20, Tom22, and Tom70 in a presequence-carrying preprotein and a non-cleavable preprotein. J Biol Chem (1999) 1.50
Purification of Saccharomcyes cerevisiae mitochondria devoid of microsomal and cytosolic contaminations. Anal Biochem (2000) 1.48
Targeting of the master receptor MOM19 to mitochondria. Science (1991) 1.48
The essential yeast protein MIM44 (encoded by MPI1) is involved in an early step of preprotein translocation across the mitochondrial inner membrane. Mol Cell Biol (1993) 1.43
Deletion of the receptor MOM19 strongly impairs import of cleavable preproteins into Saccharomyces cerevisiae mitochondria. J Biol Chem (1994) 1.42
Membrane potential-driven protein import into mitochondria. The sorting sequence of cytochrome b(2) modulates the deltapsi-dependence of translocation of the matrix-targeting sequence. Mol Biol Cell (2000) 1.39
Mitochondrial protein import. Bypass of proteinaceous surface receptors can occur with low specificity and efficiency. J Biol Chem (1989) 1.36
Insertion of MOM22 into the mitochondrial outer membrane strictly depends on surface receptors. FEBS Lett (1993) 1.35
Mechanisms of protein translocation into mitochondria. Biochim Biophys Acta (1999) 1.33
The intermembrane space domain of mitochondrial Tom22 functions as a trans binding site for preproteins with N-terminal targeting sequences. Mol Cell Biol (1997) 1.33
Precursor proteins in transit through mitochondrial contact sites interact with hsp70 in the matrix. FEBS Lett (1990) 1.31
Mitochondrial preproteins en route from the outer membrane to the inner membrane are exposed to the intermembrane space. FEBS Lett (1991) 1.30
Cyclophilin 20 is involved in mitochondrial protein folding in cooperation with molecular chaperones Hsp70 and Hsp60. Mol Cell Biol (1995) 1.29
Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins. EMBO J (1996) 1.28
Mitochondrial GrpE is present in a complex with hsp70 and preproteins in transit across membranes. Mol Cell Biol (1994) 1.27
Protein folding causes an arrest of preprotein translocation into mitochondria in vivo. J Cell Biol (1991) 1.26
Mitochondrial porin of Neurospora crassa: cDNA cloning, in vitro expression and import into mitochondria. EMBO J (1987) 1.25
Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway. Mol Biol Cell (1999) 1.25
Characterization of the preprotein translocase of the outer mitochondrial membrane by blue native electrophoresis. Biol Chem (1997) 1.23
Identification of MIM23, a putative component of the protein import machinery of the mitochondrial inner membrane. FEBS Lett (1993) 1.22
Genetic and biochemical dissection of the mitochondrial protein-import machinery. Curr Genet (1995) 1.22
The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation. EMBO J (2001) 1.20
The mitochondrial receptor complex: Mom22 is essential for cell viability and directly interacts with preproteins. Mol Cell Biol (1995) 1.20
The cleavable presequence is not essential for import and assembly of the phosphate carrier of mammalian mitochondria but enhances the specificity and efficiency of import. J Biol Chem (1992) 1.19
Specific recognition of mitochondrial preproteins by the cytosolic domain of the import receptor MOM72. J Biol Chem (1994) 1.19
Mitochondrial import of subunit Va of cytochrome c oxidase characterized with yeast mutants. J Biol Chem (1995) 1.18
Mitochondrial receptor complex from Neurospora crassa and Saccharomyces cerevisiae. Methods Enzymol (1995) 1.16
The mitochondrial receptor complex: the small subunit Mom8b/Isp6 supports association of receptors with the general insertion pore and transfer of preproteins. Mol Cell Biol (1995) 1.15
Mitochondrial protein import: specific recognition and membrane translocation of preproteins. J Membr Biol (1993) 1.12
Energy requirements for unfolding and membrane translocation of precursor proteins during import into mitochondria. J Biol Chem (1990) 1.11
Identification of the mitochondrial receptor complex in Saccharomyces cerevisiae. FEBS Lett (1992) 1.11
Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane. Biochem J (1998) 1.09
The mitochondrial protein import machinery. Role of ATP in dissociation of the Hsp70.Mim44 complex. J Biol Chem (1995) 1.07
Analysis of the sorting signals directing NADH-cytochrome b5 reductase to two locations within yeast mitochondria. Mol Cell Biol (1997) 1.06
Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane. EMBO J (1997) 1.06
Identification of the essential yeast protein MIM17, an integral mitochondrial inner membrane protein involved in protein import. FEBS Lett (1994) 1.06
Mitochondrial GrpE modulates the function of matrix Hsp70 in translocation and maturation of preproteins. Mol Cell Biol (1995) 1.05
The mitochondrial import receptor Tom70: identification of a 25 kDa core domain with a specific binding site for preproteins. J Mol Biol (2000) 1.04
Mitochondrial import receptors for precursor proteins. Trends Biochem Sci (1991) 1.03
Targeting of a chemically pure preprotein to mitochondria does not require the addition of a cytosolic signal recognition factor. J Biol Chem (1992) 1.03
The import route of ADP/ATP carrier into mitochondria separates from the general import pathway of cleavable preproteins at the trans side of the outer membrane. J Biol Chem (1998) 1.03