Published in J Nutr on April 01, 2003
Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status. J Nutr (2009) 1.09
Inflammation causes tissue-specific depletion of vitamin B6. Arthritis Res Ther (2005) 0.99
Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. Arthritis Res Ther (2005) 0.89
Blood lipid profiles and peripheral blood mononuclear cell cholesterol metabolism gene expression in patients with and without methotrexate treatment. BMC Med (2011) 0.89
Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo. Mol Med (2012) 0.84
RASSF6 expression in adipocytes is down-regulated by interaction with macrophages. PLoS One (2013) 0.81
Biomarkers of one-carbon metabolism are associated with biomarkers of inflammation in women. J Nutr (2014) 0.80
Effects of Vitamin B6 Deficiency on the Composition and Functional Potential of T Cell Populations. J Immunol Res (2017) 0.75
Novel spectrophotometric method for the quantitation of urinary xanthurenic acid and its application in identifying individuals with hyperhomocysteinemia associated with Vitamin B₆ deficiency. Biomed Res Int (2013) 0.75
Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med (2006) 15.60
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med (2002) 11.20
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74
The healthcare costs of sarcopenia in the United States. J Am Geriatr Soc (2004) 4.84
Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr (2007) 4.37
Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med (2004) 4.34
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci U S A (2002) 4.22
Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Circulation (2003) 4.09
Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA (2009) 3.62
Skeletal muscle cutpoints associated with elevated physical disability risk in older men and women. Am J Epidemiol (2004) 3.33
Autoantibodies to folate receptors in the cerebral folate deficiency syndrome. N Engl J Med (2005) 3.17
Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer. J Natl Cancer Inst (2003) 2.92
A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiol Biomarkers Prev (2007) 2.91
A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes. Diabetes Care (2002) 2.91
Tai Chi is effective in treating knee osteoarthritis: a randomized controlled trial. Arthritis Rheum (2009) 2.63
Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial. Circulation (2011) 2.62
C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study. Circ Cardiovasc Qual Outcomes (2008) 2.50
Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. Am J Clin Nutr (2002) 2.47
Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc (2011) 2.34
Relations of biomarkers of distinct pathophysiological pathways and atrial fibrillation incidence in the community. Circulation (2010) 2.32
Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. Am J Med (2005) 2.29
Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. J Nutr (2006) 2.25
Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study. Ann Intern Med (2003) 2.20
Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides. AIDS (2005) 2.16
Common variants of FUT2 are associated with plasma vitamin B12 levels. Nat Genet (2008) 2.07
The effects of multidimensional home-based exercise on functional performance in elderly people. J Gerontol A Biol Sci Med Sci (2004) 1.97
Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Mol Med (2008) 1.97
A multi-marker approach to predict incident CKD and microalbuminuria. J Am Soc Nephrol (2010) 1.95
Folic acid intake from fortification in United States exceeds predictions. J Nutr (2002) 1.94
Anthropometric assessment of 10-y changes in body composition in the elderly. Am J Clin Nutr (2004) 1.92
Chronic cigarette smoking is associated with diminished folate status, altered folate form distribution, and increased genetic damage in the buccal mucosa of healthy adults. Am J Clin Nutr (2006) 1.89
Use of mass spectrometry to identify protein biomarkers of disease severity in the synovial fluid and serum of patients with rheumatoid arthritis. Arthritis Rheum (2004) 1.82
A method to assess genomic DNA methylation using high-performance liquid chromatography/electrospray ionization mass spectrometry. Anal Chem (2002) 1.81
Muscle fiber size and function in elderly humans: a longitudinal study. J Appl Physiol (1985) (2008) 1.76
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr (2006) 1.71
Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial. Am J Clin Nutr (2004) 1.70
Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans. Bone (2005) 1.69
High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial. Stroke (2008) 1.67
Total homocysteine lowering treatment among coronary artery disease patients in the era of folic acid-fortified cereal grain flour. Arterioscler Thromb Vasc Biol (2002) 1.66
Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation (2007) 1.65
Homocysteine levels and decline in physical function: MacArthur Studies of Successful Aging. Am J Med (2002) 1.63
Eating behavior correlates of adult weight gain and obesity in healthy women aged 55-65 y. Am J Clin Nutr (2002) 1.60
Relationship between homocysteine and mortality in chronic kidney disease. Circulation (2006) 1.58
Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Int J Med Sci (2006) 1.52
Insulin-like growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: the Framingham Heart Study. J Am Geriatr Soc (2003) 1.51
The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population. Int J Geriatr Psychiatry (2006) 1.50
Cachexia in rheumatoid arthritis. Int J Cardiol (2002) 1.47
Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384. Clin Infect Dis (2007) 1.47
Biomarkers of vitamin B-12 status in NHANES: a roundtable summary. Am J Clin Nutr (2011) 1.43
Biomarkers of folate status in NHANES: a roundtable summary. Am J Clin Nutr (2011) 1.43
Testosterone and growth hormone improve body composition and muscle performance in older men. J Clin Endocrinol Metab (2009) 1.40
Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men. Br J Clin Pharmacol (2003) 1.40
Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia. J Cachexia Sarcopenia Muscle (2012) 1.37
B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice. Proc Natl Acad Sci U S A (2008) 1.37
Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004. Am J Clin Nutr (2008) 1.37
Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study. Eur Heart J (2004) 1.37
Recent advances in the biology and therapy of muscle wasting. Ann N Y Acad Sci (2010) 1.36
Plasma vitamin B6 and the risk of colorectal cancer and adenoma in women. J Natl Cancer Inst (2005) 1.36
Circulating folic acid in plasma: relation to folic acid fortification. Am J Clin Nutr (2008) 1.35
The atherogenic effect of excess methionine intake. Proc Natl Acad Sci U S A (2003) 1.35
Multiple biomarkers and the risk of incident hypertension. Hypertension (2007) 1.34
Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells. Brain (2008) 1.34
Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet. Age (Dordr) (2006) 1.33
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. Hum Mol Genet (2009) 1.33
Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. Am J Clin Nutr (2010) 1.32
Resistance training to reduce the malnutrition-inflammation complex syndrome of chronic kidney disease. Am J Kidney Dis (2004) 1.32
Erroneous augmentation of multiplex assay measurements in patients with rheumatoid arthritis due to heterophilic binding by serum rheumatoid factor. Arthritis Rheum (2011) 1.31
Homocysteine as a risk factor for coronary heart diseases and its association with inflammatory biomarkers, lipids and dietary factors. Atherosclerosis (2004) 1.30
Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction. JAMA (2003) 1.30
A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma. Am J Clin Nutr (2009) 1.28
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384. J Acquir Immune Defic Syndr (2007) 1.27
Protective effects of fish intake and interactive effects of long-chain polyunsaturated fatty acid intakes on hip bone mineral density in older adults: the Framingham Osteoporosis Study. Am J Clin Nutr (2011) 1.26
Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women. Am J Clin Nutr (2008) 1.26
Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study. Circulation (2008) 1.26
A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate. J Nutr (2008) 1.22
Effect of vitamin E and eccentric exercise on selected biomarkers of oxidative stress in young and elderly men. Free Radic Biol Med (2003) 1.18
Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. J Nutr (2005) 1.17
Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides. J Nutr (2005) 1.17
Elevated serum methylmalonic acid concentrations are common among elderly Americans. J Nutr (2002) 1.17
Not all cases of neural-tube defect can be prevented by increasing the intake of folic acid. Br J Nutr (2008) 1.15
Multimarker approach for the prediction of heart failure incidence in the community. Circulation (2010) 1.15
Enhancement of folates in plants through metabolic engineering. Proc Natl Acad Sci U S A (2004) 1.15
Dietary intakes of arachidonic acid and alpha-linolenic acid are associated with reduced risk of hip fracture in older adults. J Nutr (2011) 1.15
Prediagnostic plasma folate and the risk of death in patients with colorectal cancer. J Clin Oncol (2008) 1.14
One-carbon metabolism biomarkers and risk of colon and rectal cancers. Cancer Epidemiol Biomarkers Prev (2008) 1.14
Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model. Teratology (2002) 1.13
Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase. J Biol Chem (2006) 1.13
Low plasma vitamin B12 is associated with lower BMD: the Framingham Osteoporosis Study. J Bone Miner Res (2004) 1.13
Tai Chi for treating knee osteoarthritis: designing a long-term follow up randomized controlled trial. BMC Musculoskelet Disord (2008) 1.13
Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial. J Acquir Immune Defic Syndr (2006) 1.12
Tumor necrosis factor-alpha production is associated with less body cell mass in women with rheumatoid arthritis. J Rheumatol (2004) 1.11
Strength training in older women: early and late changes in whole muscle and single cells. Muscle Nerve (2003) 1.11
Homocysteine and cognitive performance in the Framingham offspring study: age is important. Am J Epidemiol (2005) 1.10
The role of cytokines in regulating protein metabolism and muscle function. Nutr Rev (2002) 1.10
Vitamin B-6 intake is inversely related to, and the requirement is affected by, inflammation status. J Nutr (2009) 1.09
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr (2013) 1.08
Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium. J Nutr (2004) 1.07