Published in Hum Mol Genet on October 07, 2003
Genomewide association for schizophrenia in the CATIE study: results of stage 1. Mol Psychiatry (2008) 4.14
The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J Med Genet (2005) 4.02
Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophr Bull (2005) 3.93
Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol (2008) 3.13
Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nat Rev Neurosci (2011) 2.89
Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am J Hum Genet (2004) 2.71
Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc Natl Acad Sci U S A (2005) 2.68
The genetic deconstruction of psychosis. Schizophr Bull (2007) 2.25
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice. Proc Natl Acad Sci U S A (2007) 2.04
Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry (2011) 1.93
Isolated populations and complex disease gene identification. Genome Biol (2008) 1.83
DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. Proc Natl Acad Sci U S A (2009) 1.76
A genome-wide association study of autism using the Simons Simplex Collection: Does reducing phenotypic heterogeneity in autism increase genetic homogeneity? Biol Psychiatry (2014) 1.68
Executive function, neural circuitry, and genetic mechanisms in schizophrenia. Neuropsychopharmacology (2010) 1.47
Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia. Hum Genet (2006) 1.29
Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development. J Neurosci (2010) 1.29
Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders. PLoS One (2013) 1.23
DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia. Biol Psychol (2007) 1.21
Common variants in psychiatric risk genes predict brain structure at birth. Cereb Cortex (2013) 1.20
Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging. Hum Genet (2010) 1.20
Association of variants in DISC1 with psychosis-related traits in a large population cohort. Arch Gen Psychiatry (2009) 1.19
A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Proc Natl Acad Sci U S A (2005) 1.14
Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness. Schizophr Bull (2006) 1.12
Translational research in central nervous system drug discovery. NeuroRx (2005) 1.12
The genetics of symptom-based phenotypes: toward a molecular classification of schizophrenia. Schizophr Bull (2008) 1.11
Personalized medicine in psychiatry: problems and promises. BMC Med (2013) 1.09
The Translin/Trax RNA binding complex: clues to function in the nervous system. Biochim Biophys Acta (2008) 1.09
Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population. PLoS One (2011) 1.05
Effect of antipsychotic drugs on DISC1 and dysbindin expression in mouse frontal cortex and hippocampus. J Neural Transm (Vienna) (2006) 1.03
Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia. Mol Psychiatry (2011) 1.02
Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes. Mol Psychiatry (2011) 1.01
Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses. Biol Psychiatry (2009) 0.98
A 1q42 deletion involving DISC1, DISC2, and TSNAX in an autism spectrum disorder. Am J Med Genet A (2009) 0.97
The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations. Hum Mol Genet (2009) 0.97
Common functional polymorphisms of DISC1 and cortical maturation in typically developing children and adolescents. Mol Psychiatry (2010) 0.96
An association analysis of synapse-associated protein 97 (SAP97) gene in schizophrenia. J Neural Transm (Vienna) (2008) 0.95
DISC1 is associated with cortical thickness and neural efficiency. Neuroimage (2011) 0.91
Schizophrenia in translation: disrupted in schizophrenia (DISC1): integrating clinical and basic findings. Schizophr Bull (2006) 0.91
Genome-wide association study of treatment refractory schizophrenia in Han Chinese. PLoS One (2012) 0.90
DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders. Front Psychiatry (2012) 0.90
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. Hum Mol Genet (2012) 0.89
Selective hyper-responsiveness of the interferon system in major depressive disorders and depression induced by interferon therapy. PLoS One (2012) 0.88
Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene. Mol Psychiatry (2013) 0.87
Imaging genomics and response to treatment with antipsychotics in schizophrenia. NeuroRx (2006) 0.87
Cortical mapping of genotype-phenotype relationships in schizophrenia. Hum Brain Mapp (2007) 0.87
Further evidence for a male-selective genetic association of synapse-associated protein 97 (SAP97) gene with schizophrenia. Behav Brain Funct (2012) 0.87
Positive association of the pericentrin (PCNT) gene with major depressive disorder in the Japanese population. J Psychiatry Neurosci (2009) 0.87
Psychosis among "healthy" siblings of schizophrenia patients. BMC Psychiatry (2006) 0.86
Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia. Dialogues Clin Neurosci (2006) 0.85
DISC1 (disrupted-in-schizophrenia-1) regulates differentiation of oligodendrocytes. PLoS One (2014) 0.84
Social cognitive role of schizophrenia candidate gene GABRB2. PLoS One (2013) 0.83
Nature and nurture in neuropsychiatric genetics: where do we stand? Dialogues Clin Neurosci (2010) 0.82
Evidence for association between Disrupted-in-Schizophrenia 1 (DISC1) gene polymorphisms and autism in Chinese Han population: a family-based association study. Behav Brain Funct (2011) 0.82
Genetic association of cyclic AMP signaling genes with bipolar disorder. Transl Psychiatry (2012) 0.81
Common variations in ALG9 are not associated with bipolar I disorder: a family-based study. Behav Brain Funct (2006) 0.81
Association study of H2AFZ with schizophrenia in a Japanese case-control sample. J Neural Transm (Vienna) (2014) 0.80
Allele-specific regulation of DISC1 expression by miR-135b-5p. Eur J Hum Genet (2013) 0.78
Analysis of the DISC1 translocation partner (11q14.3) in genetic risk of schizophrenia. Genes Brain Behav (2012) 0.78
A Disrupted-in-Schizophrenia 1 Gene Variant is Associated with Clinical Symptomatology in Patients with First-Episode Psychosis. Psychiatry Investig (2014) 0.76
Monoamine oxidase a and B gene polymorphisms and negative and positive symptoms in schizophrenia. ISRN Psychiatry (2012) 0.76
Common variants in the MKL1 gene confer risk of schizophrenia. Schizophr Bull (2014) 0.76
Caveolin-1 Regulation of Disrupted-in-Schizophrenia-1 as a Potential Therapeutic Target for Schizophrenia. J Neurophysiol (2016) 0.75
Sequence variation in IGF1R is associated with differences in insulin levels in nondiabetic Old Order Amish. Diabetes Metab Res Rev (2009) 0.75
Molecular genetics of the psychosis phenotype. Can J Psychiatry (2012) 0.75
Neuregulin-1 Regulates Cortical Inhibitory Neuron Dendrite and Synapse Growth through DISC1. Neural Plast (2016) 0.75
Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness. Mol Neuropsychiatry (2015) 0.75
Genetic Consideration of Schizotypal Traits: A Review. Front Psychol (2016) 0.75
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet (2008) 12.07
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol (2013) 7.97
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Identification of a variant associated with adult-type hypolactasia. Nat Genet (2002) 7.49
11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet (2009) 7.45
Multiple common variants for celiac disease influencing immune gene expression. Nat Genet (2010) 6.90
A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet (2007) 6.87
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med (2012) 6.77
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Lifetime prevalence of psychotic and bipolar I disorders in a general population. Arch Gen Psychiatry (2007) 6.20
A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses. Lancet (2010) 6.07
Aire regulates negative selection of organ-specific T cells. Nat Immunol (2003) 5.85
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56
Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA (2009) 5.32
New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
Classical twin studies and beyond. Nat Rev Genet (2002) 4.81
Disruption of the neurexin 1 gene is associated with schizophrenia. Hum Mol Genet (2008) 4.78
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61
Rationale, design, and methodology of the Women's Genome Health Study: a genome-wide association study of more than 25,000 initially healthy american women. Clin Chem (2007) 4.45
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study. Am J Hum Genet (2008) 4.31
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes (2008) 4.20
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat Genet (2012) 4.08
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype. Am J Hum Genet (2002) 4.06
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med (2005) 4.06
Nocturia frequency, bother, and quality of life: how often is too often? A population-based study in Finland. Eur Urol (2009) 3.92
Completed suicide after a suicide attempt: a 37-year follow-up study. Am J Psychiatry (2004) 3.92
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure. Nat Genet (2009) 3.81
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
A nationwide cohort study of oral and depot antipsychotics after first hospitalization for schizophrenia. Am J Psychiatry (2011) 3.71
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat Genet (2010) 3.58
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet (2006) 3.54
Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci. PLoS Genet (2007) 3.47
Genetic structure of Europeans: a view from the North-East. PLoS One (2009) 3.46
Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056. Sci Transl Med (2011) 3.46
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet (2010) 3.34
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Nat Genet (2011) 3.06
Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum Mol Genet (2002) 2.91
Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study. Lancet (2004) 2.91
Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1). Nat Genet (2004) 2.86
The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet (2008) 2.79
Biobanking for Europe. Brief Bioinform (2007) 2.76
MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome. Nat Genet (2006) 2.75