Published in Development on April 01, 2004
Role of platelet-derived growth factors in physiology and medicine. Genes Dev (2008) 8.89
Pericytes regulate the blood-brain barrier. Nature (2010) 6.62
Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol (2008) 5.06
Central nervous system pericytes in health and disease. Nat Neurosci (2011) 2.90
Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers. J Clin Invest (2005) 2.80
Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood (2009) 2.73
Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice. Nat Genet (2013) 2.62
Cytokine detection by antibody-based proximity ligation. Proc Natl Acad Sci U S A (2004) 2.29
Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood (2010) 1.81
Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity. Sci Transl Med (2013) 1.69
Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J (2006) 1.69
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development. Genes Dev (2007) 1.68
Endothelial-cardiomyocyte interactions in cardiac development and repair. Annu Rev Physiol (2006) 1.68
Integrin alpha4beta1-VCAM-1-mediated adhesion between endothelial and mural cells is required for blood vessel maturation. J Clin Invest (2005) 1.61
Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease. Front Neuroenergetics (2010) 1.59
Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev Biol (2008) 1.59
An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature. Genes Dev (2005) 1.47
PDGFRβ signaling regulates mural cell plasticity and inhibits fat development. Dev Cell (2011) 1.45
Protective role of insulin-like growth factor-1 receptor in endothelial cells against unilateral ureteral obstruction-induced renal fibrosis. Am J Pathol (2015) 1.45
Multiplexed homogeneous proximity ligation assays for high-throughput protein biomarker research in serological material. Mol Cell Proteomics (2011) 1.39
Molecular basis for endothelial lumen formation and tubulogenesis during vasculogenesis and angiogenic sprouting. Int Rev Cell Mol Biol (2011) 1.36
CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One (2012) 1.33
Notch3 is critical for proper angiogenesis and mural cell investment. Circ Res (2010) 1.27
Tips, stalks, tubes: notch-mediated cell fate determination and mechanisms of tubulogenesis during angiogenesis. Cold Spring Harb Perspect Med (2012) 1.21
Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis. Proc Natl Acad Sci U S A (2008) 1.20
Endothelial cell-pericyte interactions stimulate basement membrane matrix assembly: influence on vascular tube remodeling, maturation, and stabilization. Microsc Microanal (2011) 1.20
Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors. Cancer Res (2009) 1.20
The pericyte: cellular regulator of microvascular blood flow. Microvasc Res (2009) 1.19
The CNS microvascular pericyte: pericyte-astrocyte crosstalk in the regulation of tissue survival. Fluids Barriers CNS (2011) 1.08
Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure. Blood (2007) 1.07
Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells. Proc Natl Acad Sci U S A (2011) 1.06
Cooperation between the PDGF receptors in cardiac neural crest cell migration. Dev Biol (2007) 1.06
Alteration of developmental and pathological retinal angiogenesis in angptl4-deficient mice. J Biol Chem (2011) 1.05
Mesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1. Am J Pathol (2011) 1.00
Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness. Microvasc Res (2010) 1.00
Brain tissue responses to neural implants impact signal sensitivity and intervention strategies. ACS Chem Neurosci (2015) 0.99
Bmp in podocytes is essential for normal glomerular capillary formation. J Am Soc Nephrol (2008) 0.98
Molecular mediators of angiogenesis. J Burn Care Res (2010) 0.98
'Sealing off the CNS': cellular and molecular regulation of blood-brain barriergenesis. Curr Opin Neurobiol (2013) 0.97
Regulation of tissue morphogenesis by endothelial cell-derived signals. Trends Cell Biol (2014) 0.97
TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB. Am J Physiol Cell Physiol (2009) 0.95
Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo. Am J Pathol (2009) 0.95
Platelet-derived growth factor receptor beta is critical for zebrafish intersegmental vessel formation. PLoS One (2010) 0.94
The PDGF family in renal fibrosis. Pediatr Nephrol (2011) 0.94
In vitro models of angiogenesis and vasculogenesis in fibrin gel. Exp Cell Res (2013) 0.93
Regulation of vascular integrity. J Mol Med (Berl) (2009) 0.92
Effects of caspase-1 knockout on chronic neural recording quality and longevity: insight into cellular and molecular mechanisms of the reactive tissue response. Biomaterials (2014) 0.92
Glomerular endothelial cell injury and cross talk in diabetic kidney disease. Am J Physiol Renal Physiol (2014) 0.91
Signaling required for blood vessel maintenance: molecular basis and pathological manifestations. Int J Vasc Med (2011) 0.91
ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation. J Exp Med (2012) 0.90
Signaling pathways in the development of infantile hemangioma. J Hematol Oncol (2014) 0.89
Use of proximity ligation to screen for inhibitors of interactions between vascular endothelial growth factor A and its receptors. Clin Chem (2008) 0.88
Prokineticin receptor-1 is a new regulator of endothelial insulin uptake and capillary formation to control insulin sensitivity and cardiovascular and kidney functions. J Am Heart Assoc (2013) 0.88
Foxc1 is required by pericytes during fetal brain angiogenesis. Biol Open (2013) 0.87
Platelet-derived growth factor-B normalizes micromorphology and vessel function in vascular endothelial growth factor-A-induced squamous cell carcinomas. Am J Pathol (2009) 0.87
The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development. Development (2014) 0.86
Generation of a functional liver tissue mimic using adipose stromal vascular fraction cell-derived vasculatures. Sci Rep (2013) 0.85
Contribution of endothelial cells to organogenesis: a modern reappraisal of an old Aristotelian concept. J Anat (2007) 0.85
Aligned human microvessels formed in 3D fibrin gel by constraint of gel contraction. Microvasc Res (2013) 0.85
Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling. Dev Cell (2012) 0.82
STAT1-mediated Bim expression promotes the apoptosis of retinal pericytes under high glucose conditions. Cell Death Dis (2014) 0.82
Structural and functional properties of platelet-derived growth factor and stem cell factor receptors. Cold Spring Harb Perspect Biol (2013) 0.82
Therapeutic effects of late outgrowth endothelial progenitor cells or mesenchymal stem cells derived from human umbilical cord blood on infarct repair. Int J Cardiol (2015) 0.82
Endothelium under stress: local and systemic messages. Semin Nephrol (2012) 0.81
Pericyte-derived sphingosine 1-phosphate induces the expression of adhesion proteins and modulates the retinal endothelial cell barrier. Arterioscler Thromb Vasc Biol (2011) 0.81
Fit for the Eye: Aptamers in Ocular Disorders. Nucleic Acid Ther (2016) 0.80
A CNS-specific hypomorphic Pdgfr-beta mutant model of diabetic retinopathy. Invest Ophthalmol Vis Sci (2013) 0.80
Cell-autonomous defects in thymic epithelial cells disrupt endothelial-perivascular cell interactions in the mouse thymus. PLoS One (2013) 0.80
Expression of pro- and anti-angiogenic factors during the formation of the periocular vasculature and development of the avian cornea. Dev Dyn (2013) 0.79
Exosomes from high glucose-treated glomerular endothelial cells activate mesangial cells to promote renal fibrosis. Biol Open (2016) 0.79
Crosstalk in glomerular injury and repair. Curr Opin Nephrol Hypertens (2015) 0.78
The glomerulus: the sphere of influence. Clin J Am Soc Nephrol (2014) 0.78
Development of renal renin-expressing cells does not involve PDGF-B-PDGFR-β signaling. Physiol Rep (2013) 0.78
Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development (2015) 0.78
Microvascular targets for anti-fibrotic therapeutics. Yale J Biol Med (2013) 0.78
Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy. Mol Vis (2015) 0.78
Periods of cardiovascular susceptibility to hypoxia in embryonic american alligators (Alligator mississippiensis). Am J Physiol Regul Integr Comp Physiol (2016) 0.76
Dynamic regulation of platelet-derived growth factor D (PDGF-D) activity and extracellular spatial distribution by matriptase-mediated proteolysis. J Biol Chem (2015) 0.75
Interaction between pericytes and endothelial cells leads to formation of tight junction in hyaloid vessels. Mol Cells (2013) 0.75
Mechanisms of cellular plasticity in cerebral perivascular region. Prog Brain Res (2016) 0.75
Pdgfrb is a direct regulatory target of TGFβ signaling in atrioventricular cushion mesenchymal cells. PLoS One (2017) 0.75
New Data from Pdfgb (ret/ret) Mutant Mice Might Lead to a Paradoxical Association Between Brain Calcification, Pericytes Recruitment and BBB Integrity. J Mol Neurosci (2017) 0.75
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol (2003) 12.96
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med (2007) 9.51
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature (2007) 9.09
Role of platelet-derived growth factors in physiology and medicine. Genes Dev (2008) 8.89
Endothelial/pericyte interactions. Circ Res (2005) 8.24
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol (2003) 7.42
Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature (2008) 7.28
Pericytes regulate the blood-brain barrier. Nature (2010) 6.62
Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell (2011) 6.12
Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes Dev (2002) 5.15
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature (2008) 5.15
SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. Cell (2008) 5.02
ILK, PINCH and parvin: the tIPP of integrin signalling. Nat Rev Mol Cell Biol (2006) 4.64
A new method for large scale isolation of kidney glomeruli from mice. Am J Pathol (2002) 4.63
Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med (2008) 4.55
The tail of integrins, talin, and kindlins. Science (2009) 4.51
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. Cell (2006) 4.43
Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res (2003) 4.39
Multigene amplification and massively parallel sequencing for cancer mutation discovery. Proc Natl Acad Sci U S A (2007) 3.93
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature (2012) 3.80
Endothelial-mural cell signaling in vascular development and angiogenesis. Arterioscler Thromb Vasc Biol (2009) 3.78
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke. Nat Med (2008) 3.64
Genetic and cell biological analysis of integrin outside-in signaling. Genes Dev (2009) 3.57
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall. Genes Dev (2003) 3.48
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med (2013) 3.35
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J Clin Invest (2003) 3.31
Kindlin-2 controls bidirectional signaling of integrins. Genes Dev (2008) 3.15
The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation. Dev Cell (2006) 3.10
Caspase-8 serves both apoptotic and nonapoptotic roles. J Immunol (2004) 3.09
Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells. Nat Med (2009) 2.85
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. J Clin Invest (2008) 2.77
Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy. EMBO J (2002) 2.73
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation. Genes Dev (2003) 2.68
Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice. Nat Genet (2013) 2.62
Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation. Nat Med (2006) 2.59
Pericytes limit tumor cell metastasis. J Clin Invest (2006) 2.55
β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments. Nat Cell Biol (2013) 2.52
Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. Nat Cell Biol (2008) 2.46
Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo. J Exp Med (2007) 2.43
Pericytes and vascular stability. Exp Cell Res (2005) 2.39
The Kindlins: subcellular localization and expression during murine development. Exp Cell Res (2006) 2.36
Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon. Neuron (2003) 2.31
Pericytes and the pathogenesis of diabetic retinopathy. Diabetes (2002) 2.31
Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails. J Cell Sci (2009) 2.29
Cytokine detection by antibody-based proximity ligation. Proc Natl Acad Sci U S A (2004) 2.29
The integrin-actin connection, an eternal love affair. EMBO J (2003) 2.26
Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling. Dev Biol (2003) 2.24
Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis. Genes Dev (2003) 2.21
Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae. Dev Cell (2010) 2.17
Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system. Dev Dyn (2004) 2.11
The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! EMBO J (2009) 2.10
Tenomodulin is necessary for tenocyte proliferation and tendon maturation. Mol Cell Biol (2005) 2.10
Prorenin receptor is essential for normal podocyte structure and function. J Am Soc Nephrol (2011) 2.08
The role of laminin in embryonic cell polarization and tissue organization. Dev Cell (2003) 2.05
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood (2010) 2.04
Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance. Development (2004) 2.04
A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development (2002) 2.04
Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron (2007) 2.01
Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals. Cell (2007) 2.00
Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin. Cell Stem Cell (2008) 1.98
Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice. Circ Res (2002) 1.96
Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins. EMBO Rep (2011) 1.96
Integrins in invasive growth. J Clin Invest (2002) 1.96
Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell (2006) 1.92
Analysis of mural cell recruitment to tumor vessels. Circulation (2002) 1.90
The role of integrin binding sites in fibronectin matrix assembly in vivo. Curr Opin Cell Biol (2008) 1.89
A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nat Genet (2004) 1.87
The RGD motif in fibronectin is essential for development but dispensable for fibril assembly. J Cell Biol (2007) 1.81
Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction. PLoS Genet (2008) 1.78
Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation. FASEB J (2003) 1.76
ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability. J Exp Med (2006) 1.75
Transcription profiling of platelet-derived growth factor-B-deficient mouse embryos identifies RGS5 as a novel marker for pericytes and vascular smooth muscle cells. Am J Pathol (2003) 1.74
Plasma fibronectin promotes thrombus growth and stability in injured arterioles. Proc Natl Acad Sci U S A (2003) 1.74
Genetic analysis of beta1 integrin "activation motifs" in mice. J Cell Biol (2006) 1.73
Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography. Nat Cell Biol (2010) 1.72
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res (2004) 1.72
Integrin trafficking regulated by Rab21 is necessary for cytokinesis. Dev Cell (2008) 1.70
Laminin: the crux of basement membrane assembly. J Cell Biol (2004) 1.69
Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J (2006) 1.69
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development. Genes Dev (2007) 1.68
Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res (2008) 1.68
A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy. J Clin Invest (2008) 1.67
Digital quantification using amplified single-molecule detection. Nat Methods (2006) 1.66
The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2. Dev Cell (2012) 1.66
Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts. Cancer Res (2009) 1.65
Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood (2012) 1.64
Integrin-linked kinase is required for epidermal and hair follicle morphogenesis. J Cell Biol (2007) 1.63