Published in Proc Natl Acad Sci U S A on September 01, 2004
Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron (2009) 2.97
Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells. J Biol Chem (2009) 1.82
Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms. EMBO J (2007) 1.67
Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons. Proc Natl Acad Sci U S A (2005) 1.42
Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia. Genome Biol (2009) 1.27
Tissue transglutaminase regulates matrix metalloproteinase-2 in ovarian cancer by modulating cAMP-response element-binding protein activity. J Biol Chem (2009) 1.14
Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells. BMC Genomics (2010) 1.12
cAMP/CREB-mediated transcriptional regulation of ectonucleoside triphosphate diphosphohydrolase 1 (CD39) expression. J Biol Chem (2010) 1.11
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CREB downregulation in vascular disease: a common response to cardiovascular risk. Arterioscler Thromb Vasc Biol (2010) 1.05
Molecular and cellular mechanisms of memory allocation in neuronetworks. Neurobiol Learn Mem (2007) 1.04
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A genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis. PLoS One (2013) 1.01
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A comparative genomics approach to identifying the plasticity transcriptome. BMC Neurosci (2007) 1.00
Integrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver. BMC Genomics (2013) 0.97
The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB. Mol Cell Biol (2007) 0.96
Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs. Neuron (2015) 0.96
Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons. BMC Neurosci (2005) 0.91
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Neuroplasticity in addiction: cellular and transcriptional perspectives. Front Mol Neurosci (2012) 0.88
Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity. J Biol Chem (2011) 0.85
Senescent-induced dysregulation of cAMP/CREB signaling and correlations with cognitive decline. Brain Res (2013) 0.85
Mitogen and stress activated kinases act co-operatively with CREB during the induction of human cytomegalovirus immediate-early gene expression from latency. PLoS Pathog (2014) 0.82
Bipartite functions of the CREB co-activators selectively direct alternative splicing or transcriptional activation. EMBO J (2009) 0.81
Ethanol sensitivity: a central role for CREB transcription regulation in the cerebellum. BMC Genomics (2006) 0.81
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Biological functions and transcriptional targets of CaRF in neurons. Cell Calcium (2011) 0.79
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Allele-specific binding of airway nuclear extracts to polymorphic beta2-adrenergic receptor 5' sequence. Am J Respir Cell Mol Biol (2007) 0.78
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Beyond phosphorylation: nuclear export in vascular remodeling. Arterioscler Thromb Vasc Biol (2011) 0.77
Gene expression and transcription factor profiling reveal inhibition of transcription factor cAMP-response element-binding protein by gamma-herpesvirus replication and transcription activator. J Biol Chem (2010) 0.77
Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models. Front Behav Neurosci (2016) 0.76
Bidirectional promoters link cAMP signaling with irreversible differentiation through promoter-associated non-coding RNA (pancRNA) expression in PC12 cells. Nucleic Acids Res (2016) 0.76
Serine 133 phosphorylation is not required for hippocampal CREB-mediated transcription and behavior. Learn Mem (2015) 0.76
Single-Molecule Imaging Reveals Dynamics of CREB Transcription Factor Bound to Its Target Sequence. Sci Rep (2015) 0.76
The α and Δ isoforms of CREB1 are required to maintain normal pulmonary vascular resistance. PLoS One (2013) 0.76
Selective genomic targeting by FRA-2/FOSL2 transcription factor: regulation of the Rgs4 gene is mediated by a variant activator protein 1 (AP-1) promoter sequence/CREB-binding protein (CBP) mechanism. J Biol Chem (2011) 0.76
β-agonists selectively modulate proinflammatory gene expression in skeletal muscle cells via non-canonical nuclear crosstalk mechanisms. PLoS One (2014) 0.75
Genome-wide analysis identifies colonic genes differentially associated with serum leptin and insulin concentrations in C57BL/6J mice fed a high-fat diet. PLoS One (2017) 0.75
The transcriptional repressor ICER binds to multiple loci throughout the genome. Biochem Biophys Res Commun (2016) 0.75
CREB Regulates Distinct Adaptive Transcriptional Programs in Astrocytes and Neurons. Sci Rep (2017) 0.75
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The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding. J Biol Chem (2000) 1.36
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CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas. J Biol Chem (1996) 1.26
Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: DNA methylation alone is not sufficient to prevent protein binding in vivo. EMBO J (1991) 1.23
Temporal and spatial changes in transcription factor binding and histone modifications at the steroidogenic acute regulatory protein (stAR) locus associated with stAR transcription. Mol Endocrinol (2004) 1.22
Cutting edge: clonally restricted production of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors. J Immunol (1999) 1.16
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A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A (2005) 6.61
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microRNA modulation of circadian-clock period and entrainment. Neuron (2007) 4.49
Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2. Neuron (2006) 4.10
An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc Natl Acad Sci U S A (2008) 3.98
Regulation of corepressor function by nuclear NADH. Science (2002) 3.83
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat Neurosci (2007) 3.81
CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sci U S A (2002) 3.32
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. Hum Mol Genet (2011) 2.60
A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions. J Neurosci (2007) 2.45
Phosphorylation of CBP mediates transcriptional activation by neural activity and CaM kinase IV. Neuron (2002) 2.45
Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP. Cell (2003) 2.42
microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus. Proc Natl Acad Sci U S A (2010) 2.28
An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling. Mol Cell Neurosci (2009) 2.28
C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs. Proc Natl Acad Sci U S A (2003) 2.25
Retracted Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex. Proc Natl Acad Sci U S A (2007) 2.09
Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor. Proc Natl Acad Sci U S A (2003) 2.03
Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins. Biochem J (2010) 1.94
Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins. J Neurosci (2004) 1.91
Wnt/β-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells. J Biol Chem (2012) 1.89
Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells. Proc Natl Acad Sci U S A (2007) 1.89
Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq. Nucleic Acids Res (2010) 1.81
Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming. Cancer Res (2011) 1.73
Redox sensor CtBP mediates hypoxia-induced tumor cell migration. Proc Natl Acad Sci U S A (2006) 1.67
Skin blood flow and local temperature independently modify sweat rate during passive heat stress in humans. J Appl Physiol (1985) (2010) 1.64
MicroRNA regulation of neural stem cells and neurogenesis. J Neurosci (2010) 1.64
CREB-mediated Bcl-2 protein expression after ischemic preconditioning. J Cereb Blood Flow Metab (2005) 1.60
Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal. J Neurosci (2002) 1.58
Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I. J Neurosci (2004) 1.57
Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory. PLoS One (2010) 1.53
Activity-dependent neuroprotection and cAMP response element-binding protein (CREB): kinase coupling, stimulus intensity, and temporal regulation of CREB phosphorylation at serine 133. J Neurosci (2005) 1.51
Deacetylase activity is required for cAMP activation of a subset of CREB target genes. J Biol Chem (2003) 1.48
Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons. Proc Natl Acad Sci U S A (2005) 1.42
A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. Mol Cell Biol (2008) 1.42
SSRP1 functions as a co-activator of the transcriptional activator p63. EMBO J (2002) 1.39
A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers. Proc Natl Acad Sci U S A (2009) 1.37
Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis. Proc Natl Acad Sci U S A (2005) 1.35
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Hippocampal CRE-mediated gene expression is required for contextual memory formation. Nat Neurosci (2002) 1.33
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Recent insights into carotid baroreflex function in humans using the variable pressure neck chamber. Exp Physiol (2003) 1.23
Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK. J Neurosci (2003) 1.21
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miRNA-132: a dynamic regulator of cognitive capacity. Brain Struct Funct (2012) 1.02
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