Published in J Cell Biol on October 25, 2004
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell (2008) 2.94
c-Met is essential for wound healing in the skin. J Cell Biol (2007) 1.98
Neutrophil microtubules suppress polarity and enhance directional migration. Proc Natl Acad Sci U S A (2005) 1.81
Microtubule function in fibroblast spreading is modulated according to the tension state of cell-matrix interactions. Proc Natl Acad Sci U S A (2007) 1.80
A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells. J Cell Sci (2009) 1.55
Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth. J Cell Sci (2009) 1.28
Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell (2010) 1.25
Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure. Dev Biol (2008) 1.12
The flare gene, which encodes the AIP1 protein of Drosophila, functions to regulate F-actin disassembly in pupal epidermal cells. Genetics (2007) 1.10
Tubulin tyrosination is required for the proper organization and pathfinding of the growth cone. PLoS One (2009) 0.95
Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila. Genetics (2010) 0.94
Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics. Mol Cell Biol (2013) 0.93
Elimination of epiplakin by gene targeting results in acceleration of keratinocyte migration in mice. Mol Cell Biol (2006) 0.89
Prominent actin fiber arrays in Drosophila tendon cells represent architectural elements different from stress fibers. Mol Biol Cell (2008) 0.88
Role of the cytoskeleton in flow (shear stress)-induced dilation and remodeling in resistance arteries. Med Biol Eng Comput (2008) 0.88
Stress-induced cleavage of Myc promotes cancer cell survival. Genes Dev (2014) 0.87
Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. Am J Hum Genet (2011) 0.86
CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation. Neural Plast (2015) 0.85
Phosphorylation of the proline-rich domain of Xp95 modulates Xp95 interaction with partner proteins. Biochem J (2007) 0.84
Golgi Feels Its Own Wound. Adv Wound Care (New Rochelle) (2013) 0.80
Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin. Cytoskeleton (Hoboken) (2014) 0.79
Monitoring the cytoskeletal EGF response in live gastric carcinoma cells. PLoS One (2012) 0.78
A novel pathway of TEF regulation mediated by microRNA-125b contributes to the control of actin distribution and cell shape in fibroblasts. PLoS One (2011) 0.77
CRMP‑5 interacts with actin to regulate neurite outgrowth. Mol Med Rep (2015) 0.75
A novel approach to select differential pathways associated with hypertrophic cardiomyopathy based on gene co‑expression analysis. Mol Med Rep (2017) 0.75
CRMPs colocalize and interact with cytoskeleton in hippocampal neurons. Int J Clin Exp Med (2015) 0.75
Rho GTPases and the actin cytoskeleton. Science (1998) 28.19
Beyond self-assembly: from microtubules to morphogenesis. Cell (1986) 10.53
Role of integrins in cell invasion and migration. Nat Rev Cancer (2002) 7.64
Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell (2001) 7.07
Localized Rac activation dynamics visualized in living cells. Science (2000) 7.00
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell (2003) 6.46
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature (2003) 6.09
Conserved microtubule-actin interactions in cell movement and morphogenesis. Nat Cell Biol (2003) 5.29
Integrins regulate Rac targeting by internalization of membrane domains. Science (2004) 5.07
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell (2002) 4.68
EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration. Nat Cell Biol (2004) 4.55
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol Cell Biol (2002) 4.50
Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton. Nat Cell Biol (2002) 4.49
Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle. J Cell Biol (2002) 4.40
Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts. Nat Cell Biol (1999) 4.08
Localized stabilization of microtubules by integrin- and FAK-facilitated Rho signaling. Science (2004) 3.93
mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat Cell Biol (2001) 3.71
Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. Cell (2003) 3.66
Microtubule targeting of substrate contacts promotes their relaxation and dissociation. J Cell Biol (1999) 3.53
Microtubule "plus-end-tracking proteins": The end is just the beginning. Cell (2001) 3.43
Roles of Rho-family GTPases in cell polarisation and directional migration. Curr Opin Cell Biol (2003) 3.31
Dynein binds to beta-catenin and may tether microtubules at adherens junctions. Nat Cell Biol (2001) 3.06
EB1-microtubule interactions in Xenopus egg extracts: role of EB1 in microtubule stabilization and mechanisms of targeting to microtubules. Mol Biol Cell (2002) 2.92
ACF7: an essential integrator of microtubule dynamics. Cell (2003) 2.66
LIS1, CLIP-170's key to the dynein/dynactin pathway. Mol Cell Biol (2002) 2.61
Regulation of leading edge microtubule and actin dynamics downstream of Rac1. J Cell Biol (2003) 2.41
Cytoplasmic linker proteins promote microtubule rescue in vivo. J Cell Biol (2002) 2.38
Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction. Curr Biol (2003) 2.20
Cortical control of microtubule stability and polarization. Curr Opin Cell Biol (2004) 2.06
Spatial and temporal analysis of Rac activation during live neutrophil chemotaxis. Curr Biol (2002) 2.01
Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1. J Biol Chem (2003) 1.99
Centrosome positioning in interphase cells. J Cell Biol (2003) 1.97
Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16. J Biol Chem (2000) 1.90
The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain. Curr Biol (1999) 1.85
Microtubule actin cross-linking factor (MACF): a hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons. J Cell Biol (1999) 1.83
Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes. J Cell Sci (2004) 1.83
Actin, microtubules and focal adhesion dynamics during cell migration. Int J Biochem Cell Biol (2003) 1.71
The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families. J Cell Sci (2002) 1.62
An epidermal plakin that integrates actin and microtubule networks at cellular junctions. J Cell Biol (2000) 1.60
Plakins: goliaths that link cell junctions and the cytoskeleton. Nat Rev Mol Cell Biol (2004) 1.60
Integrators of the cytoskeleton that stabilize microtubules. Cell (1999) 1.56
kakapo, a gene required for adhesion between and within cell layers in Drosophila, encodes a large cytoskeletal linker protein related to plectin and dystrophin. J Cell Biol (1998) 1.49
The kakapo mutation affects terminal arborization and central dendritic sprouting of Drosophila motorneurons. J Cell Biol (1998) 1.38
Dissecting interactions between EB1, microtubules and APC in cortical clusters at the plasma membrane. J Cell Sci (2002) 1.33
The adenomatous polyposis coli protein: in the limelight out at the edge. Trends Cell Biol (2001) 1.33
Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption. J Cell Sci (2003) 1.32
The Caenorhabditis elegans vab-10 spectraplakin isoforms protect the epidermis against internal and external forces. J Cell Biol (2003) 1.30
CLIP-170 interacts with dynactin complex and the APC-binding protein EB1 by different mechanisms. Cell Motil Cytoskeleton (2003) 1.25
Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid rafts. J Virol (2004) 1.20
Maintaining epithelial integrity: a function for gigantic spectraplakin isoforms in adherens junctions. J Cell Biol (2003) 1.11
Two poles and a compass. Cell (2003) 1.10
BPAG1n4 is essential for retrograde axonal transport in sensory neurons. J Cell Biol (2003) 1.01
Lipid raft-associated GTPase signaling controls morphology and CD8+ T cell stimulatory capacity of human dendritic cells. J Immunol (2004) 0.88
Defining the epithelial stem cell niche in skin. Science (2003) 14.93
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell (2004) 10.79
Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95
Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature (2005) 6.67
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet (2006) 6.30
A skin microRNA promotes differentiation by repressing 'stemness'. Nature (2008) 5.66
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell (2009) 5.51
A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell (2009) 5.40
Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell (2008) 5.02
Sticky business: orchestrating cellular signals at adherens junctions. Cell (2003) 4.91
Links between signal transduction, transcription and adhesion in epithelial bud development. Nature (2003) 4.88
Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol (2002) 4.29
Molecular dissection of mesenchymal-epithelial interactions in the hair follicle. PLoS Biol (2005) 4.27
Dynamics between stem cells, niche, and progeny in the hair follicle. Cell (2011) 4.14
Epithelial stem cells: turning over new leaves. Cell (2007) 4.10
Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev Cell (2002) 4.01
Epidermal stem cells of the skin. Annu Rev Cell Dev Biol (2006) 3.92
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature (2011) 3.90
Tcf3 governs stem cell features and represses cell fate determination in skin. Cell (2006) 3.88
NFATc1 balances quiescence and proliferation of skin stem cells. Cell (2008) 3.81
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell (2006) 3.79
Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables. Nat Cell Biol (2003) 3.77
Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol (2004) 3.70
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev (2005) 3.67
Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature (2011) 3.64
Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature (2011) 3.56
Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia. Cancer Cell (2007) 3.55
Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev (2006) 3.51
A role for skin gammadelta T cells in wound repair. Science (2002) 3.51
Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling. Proc Natl Acad Sci U S A (2007) 3.16
In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am J Physiol Lung Cell Mol Physiol (2003) 3.08
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol (2008) 3.07
GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev (2003) 2.97
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell (2008) 2.94
Stem cells in the skin: waste not, Wnt not. Genes Dev (2003) 2.80
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell (2011) 2.80
Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics. J Cell Biol (2007) 2.79
Alpha-catenin: at the junction of intercellular adhesion and actin dynamics. Nat Rev Mol Cell Biol (2004) 2.79
Lhx2 maintains stem cell character in hair follicles. Science (2006) 2.78
Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am J Hum Genet (2003) 2.73
Catenins: keeping cells from getting their signals crossed. Dev Cell (2006) 2.70
Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (2002) 2.69
p120-catenin mediates inflammatory responses in the skin. Cell (2006) 2.66
ACF7: an essential integrator of microtubule dynamics. Cell (2003) 2.66
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol Cell (2012) 2.66
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA. J Cell Biol (2003) 2.65
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev (2011) 2.63
The hair cycle. J Cell Sci (2006) 2.58
DGCR8-dependent microRNA biogenesis is essential for skin development. Proc Natl Acad Sci U S A (2008) 2.49
RNAi screens in mice identify physiological regulators of oncogenic growth. Nature (2013) 2.46
BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties. Genes Dev (2008) 2.41
Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3β. Cell (2011) 2.36
Identification of stem cell populations in sweat glands and ducts reveals roles in homeostasis and wound repair. Cell (2012) 2.35
Tcf3: a transcriptional regulator of axis induction in the early embryo. Development (2003) 2.26
Stem cells of the skin epithelium. Proc Natl Acad Sci U S A (2003) 2.20
Desmoplakin: an unexpected regulator of microtubule organization in the epidermis. J Cell Biol (2007) 2.16
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A (2003) 2.14
Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling. Proc Natl Acad Sci U S A (2011) 2.13
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc Natl Acad Sci U S A (2011) 2.08
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat Genet (2009) 2.07
Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. J Clin Invest (2009) 2.06
Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat Med (2010) 2.01
Paracrine TGF-β signaling counterbalances BMP-mediated repression in hair follicle stem cell activation. Cell Stem Cell (2012) 1.99
Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. Proc Natl Acad Sci U S A (2004) 1.99
A family business: stem cell progeny join the niche to regulate homeostasis. Nat Rev Mol Cell Biol (2012) 1.91
A role for the primary cilium in Notch signaling and epidermal differentiation during skin development. Cell (2011) 1.83
Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin. Proc Natl Acad Sci U S A (2006) 1.77
Cyfip1 is a putative invasion suppressor in epithelial cancers. Cell (2009) 1.77
Planar cell polarity protein Celsr1 regulates endothelial adherens junctions and directed cell rearrangements during valve morphogenesis. Dev Cell (2013) 1.70
A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol (2004) 1.63
Robust control of mitotic spindle orientation in the developing epidermis. J Cell Biol (2010) 1.63
Isolation and culture of epithelial stem cells. Methods Mol Biol (2009) 1.63
Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development (2010) 1.55
Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas. Science (2014) 1.53
Targeted disruption of the murine zyxin gene. Mol Cell Biol (2003) 1.51
The harmonies played by TGF-β in stem cell biology. Cell Stem Cell (2012) 1.47
Structure and transcription of the human m3 muscarinic receptor gene. Am J Respir Cell Mol Biol (2002) 1.47
Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory. J Neurosci (2006) 1.42
Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer. Proc Natl Acad Sci U S A (2008) 1.40
AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. J Cell Biol (2006) 1.38
Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation. Nat Cell Biol (2011) 1.37
New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity. Proc Natl Acad Sci U S A (2008) 1.37
A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics. Dev Cell (2003) 1.35
SOX9: a stem cell transcriptional regulator of secreted niche signaling factors. Genes Dev (2014) 1.34
Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine. Mol Cell Biol (2006) 1.33
Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment. Cell Stem Cell (2011) 1.33
AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis. J Cell Biol (2008) 1.33
What does the concept of the stem cell niche really mean today? BMC Biol (2012) 1.32
p63: revving up epithelial stem-cell potential. Nat Cell Biol (2007) 1.32
An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration. Nature (2012) 1.32
NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Nature (2013) 1.29
Mitotic internalization of planar cell polarity proteins preserves tissue polarity. Nat Cell Biol (2011) 1.28
The LEF1/beta -catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiation. Proc Natl Acad Sci U S A (2002) 1.27
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling. Proc Natl Acad Sci U S A (2013) 1.26
Mice cloned from skin cells. Proc Natl Acad Sci U S A (2007) 1.23
Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle. J Cell Biol (2005) 1.20
MicroRNAs and their roles in mammalian stem cells. J Cell Sci (2011) 1.19
A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells. J Cell Biol (2002) 1.19
Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol Cell Biol (2002) 1.18