Genetic approaches to addiction: genes and alcohol.

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Published in Addiction on April 16, 2008

Authors

Francesca Ducci1, David Goldman

Author Affiliations

1: Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism/NIH, Rockville, MD 20892, USA. francesca.ducci@iop.kcl.ac.uk

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Association between the recombinant human serotonin transporter linked promoter region polymorphism and behavior in rhesus macaques during a separation paradigm. Dev Psychopathol (2007) 1.16

Non-human primate models of inheritance vulnerability to alcohol use disorders. Addict Biol (2006) 1.15

Sex differences in the influence of COMT Val158Met on alcoholism and smoking in plains American Indians. Alcohol Clin Exp Res (2006) 1.14

The role of the Met66 brain-derived neurotrophic factor allele in the recovery of executive functioning after combat-related traumatic brain injury. J Neurosci (2011) 1.14

BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents. Neuroimage (2009) 1.14

Patterns of menstrual disturbance in eating disorders. Int J Eat Disord (2007) 1.13

OPRM1 Asn40Asp predicts response to naltrexone treatment: a haplotype-based approach. Alcohol Clin Exp Res (2008) 1.12

GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats. PLoS One (2012) 1.12

Association study of 182 candidate genes in anorexia nervosa. Am J Med Genet B Neuropsychiatr Genet (2010) 1.11

Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations. Alcohol Clin Exp Res (2010) 1.11

Haplotype-based localization of an alcohol dependence gene to the 5q34 {gamma}-aminobutyric acid type A gene cluster. Arch Gen Psychiatry (2005) 1.10

Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans. Pharmacogenet Genomics (2005) 1.10

CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhesus macaques. Arch Gen Psychiatry (2008) 1.09

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. Proc Natl Acad Sci U S A (2011) 1.09

Common genetic origins for EEG, alcoholism and anxiety: the role of CRH-BP. PLoS One (2008) 1.09

Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior. J Psychiatr Res (2011) 1.09

Effects of a alpha 2C-adrenoreceptor gene polymorphism on neural responses to facial expressions in depression. Neuropsychopharmacology (2006) 1.08

Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. Proc Natl Acad Sci U S A (2013) 1.07

Association of multiple DRD2 polymorphisms with anorexia nervosa. Neuropsychopharmacology (2005) 1.06

Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques. Arch Gen Psychiatry (2010) 1.05

Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children. Am J Psychiatry (2009) 1.05