Published in J Exp Med on November 17, 2003
How dying cells alert the immune system to danger. Nat Rev Immunol (2008) 8.63
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity (2008) 6.08
Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med (2006) 5.88
Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature (2010) 5.16
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death. J Exp Med (2005) 4.32
Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes. Nat Med (2012) 3.27
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. J Exp Med (2007) 2.86
The inflammatory response to cell death. Annu Rev Pathol (2008) 2.85
Where CD4+CD25+ T reg cells impinge on autoimmune diabetes. J Exp Med (2005) 2.61
Immune cell crosstalk in type 1 diabetes. Nat Rev Immunol (2010) 2.26
RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells. Science (2015) 2.09
Modifier loci condition autoimmunity provoked by Aire deficiency. J Exp Med (2005) 2.08
Endocrine self and gut non-self intersect in the pancreatic lymph nodes. Proc Natl Acad Sci U S A (2005) 2.06
Beta-cell mass and type 1 diabetes: going, going, gone? Diabetes (2008) 1.69
The role of dendritic cells in autoimmunity. Nat Rev Immunol (2013) 1.68
Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci U S A (2008) 1.66
Exosomes released by islet-derived mesenchymal stem cells trigger autoimmune responses in NOD mice. Diabetes (2013) 1.62
The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs. Nat Rev Immunol (2010) 1.60
Interleukin-21 is required for the development of type 1 diabetes in NOD mice. Diabetes (2009) 1.53
T regulatory cells in autoimmune diabetes: past challenges, future prospects. J Clin Immunol (2008) 1.52
Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance. J Clin Invest (2007) 1.51
Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules. Proc Natl Acad Sci U S A (2008) 1.50
Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1. PLoS Med (2005) 1.45
Natural endogenous adjuvants. Springer Semin Immunopathol (2004) 1.34
Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus. Mol Cell Biol (2005) 1.26
Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes. Diabetes (2010) 1.24
Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans. J Clin Invest (2011) 1.21
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice. J Exp Med (2004) 1.20
Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues. J Immunol (2009) 1.18
Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice. Diabetes (2008) 1.17
The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes. Proc Natl Acad Sci U S A (2008) 1.15
Soluble factors secreted by T cells promote β-cell proliferation. Diabetes (2013) 1.14
The Type 1 Diabetes PhysioLab Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse. Clin Exp Immunol (2010) 1.14
Cathepsin L is essential for onset of autoimmune diabetes in NOD mice. J Clin Invest (2005) 1.13
Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence. J Clin Invest (2010) 1.13
Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation. Endocr Rev (2008) 1.12
Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice. J Immunol (2009) 1.10
Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c+ CD11b+ dendritic cells. Proc Natl Acad Sci U S A (2012) 1.09
Antigen presentation events in autoimmune diabetes. Curr Opin Immunol (2011) 1.08
Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice. Proc Natl Acad Sci U S A (2007) 1.07
Real-time immune cell interactions in target tissue during autoimmune-induced damage and graft tolerance. J Exp Med (2014) 1.05
Activation of insulin-reactive CD8 T-cells for development of autoimmune diabetes. Diabetes (2009) 1.04
The natural killer T lymphocyte: a player in the complex regulation of autoimmune diabetes in non-obese diabetic mice. Clin Exp Immunol (2006) 1.03
Breakdown in peripheral tolerance in type 1 diabetes in mice and humans. Cold Spring Harb Perspect Med (2012) 1.00
HMGB1, an innate alarmin, in the pathogenesis of type 1 diabetes. Int J Clin Exp Pathol (2009) 1.00
The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation. Proc Natl Acad Sci U S A (2005) 0.99
Interleukin-21 receptor-mediated signals control autoreactive T cell infiltration in pancreatic islets. Immunity (2012) 0.98
Membrane repair and immunological danger. EMBO Rep (2005) 0.97
Cutting edge: merocytic dendritic cells break T cell tolerance to beta cell antigens in nonobese diabetic mouse diabetes. J Immunol (2010) 0.97
B7x in the periphery abrogates pancreas-specific damage mediated by self-reactive CD8 T cells. J Immunol (2012) 0.95
Dying cells actively regulate adaptive immune responses. Nat Rev Immunol (2017) 0.94
Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases. J Immunol (2011) 0.93
Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes. J Exp Med (2013) 0.92
The central role of antigen presentation in islets of Langerhans in autoimmune diabetes. Curr Opin Immunol (2013) 0.90
The role of innate immunity in autoimmunity. J Exp Med (2004) 0.89
B1 cells promote pancreas infiltration by autoreactive T cells. J Immunol (2010) 0.89
Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of beta cells. Blood (2007) 0.89
Apoptosis of human islet cells by cytokines. Immune Netw (2012) 0.88
Role of innate immunity in diabetes and metabolism: recent progress in the study of inflammasomes. Immune Netw (2011) 0.87
An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function. Proc Natl Acad Sci U S A (2014) 0.87
Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes. Clin Exp Immunol (2008) 0.86
Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells. Proc Natl Acad Sci U S A (2015) 0.86
Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes. Am J Ther (2005) 0.86
The Role of the Immune Response in Chlamydia trachomatis Infection of the Male Genital Tract: A Double-Edged Sword. Front Immunol (2014) 0.85
Altered immune regulation in type 1 diabetes. Clin Dev Immunol (2013) 0.85
RAE1ε ligand expressed on pancreatic islets recruits NKG2D receptor-expressing cytotoxic T cells independent of T cell receptor recognition. Immunity (2012) 0.85
A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state. Immunogenetics (2010) 0.85
Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance. Proc Natl Acad Sci U S A (2009) 0.85
Antigen-specific prevention of type 1 diabetes in NOD mice is ameliorated by OX40 agonist treatment. J Autoimmun (2011) 0.85
Mechanistic basis of immunotherapies for type 1 diabetes mellitus. Transl Res (2013) 0.84
Cell-based interventions to halt autoimmunity in type 1 diabetes mellitus. Clin Exp Immunol (2013) 0.84
CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L. J Leukoc Biol (2013) 0.84
Harnessing memory adaptive regulatory T cells to control autoimmunity in type 1 diabetes. J Mol Cell Biol (2011) 0.84
Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damage. J Immunol (2009) 0.83
MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity. PLoS One (2014) 0.83
Maternal microchimerism: increased in the insulin positive compartment of type 1 diabetes pancreas but not in infiltrating immune cells or replicating islet cells. PLoS One (2014) 0.83
TSG-6 protein expression in the pancreatic islets of NOD mice. J Mol Histol (2008) 0.82
Genes mediating environment interactions in type 1 diabetes. Rev Diabet Stud (2006) 0.82
Antigen Cross-Priming of Cell-Associated Proteins is Enhanced by Macroautophagy within the Antigen Donor Cell. Front Immunol (2012) 0.82
The pathogenicity of self-antigen decreases at high levels of autoantigenicity: a computational approach. Int Immunol (2010) 0.82
Macrophages and β-cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes. EMBO Mol Med (2014) 0.82
In vivo detection of peripherin-specific autoreactive B cells during type 1 diabetes pathogenesis. J Immunol (2014) 0.81
Annexin A1 on the surface of early apoptotic cells suppresses CD8+ T cell immunity. PLoS One (2013) 0.81
Alpha4beta7 integrin/MAdCAM-1 adhesion pathway is crucial for B cell migration into pancreatic lymph nodes in nonobese diabetic mice. J Autoimmun (2010) 0.81
Apoptosis of NOD.H2 h4 thyrocytes by low concentrations of iodide is associated with impaired control of oxidative stress. Thyroid (2014) 0.80
T cell populations in the pancreatic lymph node naturally and consistently expand and contract in NOD mice as disease progresses. Mol Immunol (2012) 0.80
Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling. J Biol Chem (2014) 0.78
Type 1 diabetes genetic susceptibility and dendritic cell function: potential targets for treatment. J Leukoc Biol (2016) 0.78
Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury: a review. Expert Opin Drug Metab Toxicol (2010) 0.78
Peroxisome Proliferator-activated Receptor-γ Activation Augments the β-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and β Cell Death in Non-obese Diabetic Mice. J Biol Chem (2016) 0.77
Treatment of autoimmune diabetes by inhibiting the initial event. Immune Netw (2013) 0.77
Despite Increased Type 1 IFN, Autoimmune Nonobese Diabetic Mice Display Impaired Dendritic Cell Response to CpG and Decreased Nuclear Localization of IFN-Activated STAT1. J Immunol (2016) 0.77
Breaking T cell tolerance to beta cell antigens by merocytic dendritic cells. Cell Mol Life Sci (2011) 0.77
Role of innate immunity in the pathogenesis of type 1 and type 2 diabetes. J Korean Med Sci (2014) 0.77
A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner. PLoS One (2013) 0.76
Are T-cell responses to GAD65 influential in type 1 diabetes? Diabetes (2009) 0.76
The role of lymphocytes in the development and treatment of alopecia areata. Expert Rev Clin Immunol (2015) 0.75
TAK1 inhibition prevents the development of autoimmune diabetes in NOD mice. Sci Rep (2015) 0.75
The Spontaneous Autoimmune Neuromyopathy in ICOSL(-/-) NOD Mice Is CD4(+) T-Cell and Interferon-γ Dependent. Front Immunol (2017) 0.75
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature (2000) 13.45
Dendritic cells: specialized and regulated antigen processing machines. Cell (2001) 10.44
Mechanisms of phagocytosis in macrophages. Annu Rev Immunol (1999) 9.66
CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo. J Exp Med (2000) 7.46
Following a diabetogenic T cell from genesis through pathogenesis. Cell (1993) 6.46
Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J Exp Med (1997) 5.53
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature (1993) 5.47
Developmental biology of the pancreas. Development (1995) 5.14
A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J Exp Med (2000) 5.11
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature (1993) 5.10
Insulin-dependent diabetes mellitus. Cell (1996) 5.06
The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo. J Exp Med (2002) 4.78
beta-Cell death during progression to diabetes. Nature (2001) 4.61
T helper cell subsets in insulin-dependent diabetes. Science (1995) 3.92
Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J Exp Med (2001) 3.90
Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes. J Exp Med (1999) 3.85
Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes. J Immunol (1997) 3.71
In vivo activation of antigen-specific CD4 T cells. Annu Rev Immunol (2001) 3.65
Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. J Exp Med (1998) 3.58
Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model. Diabetes (1995) 3.47
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science (2000) 3.12
Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2. Nat Immunol (2003) 2.90
Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J Exp Med (2002) 2.78
Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy. Diabetes (2000) 2.75
A defect in central tolerance in NOD mice. Nat Immunol (2001) 2.59
Checkpoints in the progression of autoimmune disease: lessons from diabetes models. Proc Natl Acad Sci U S A (1996) 2.53
Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat. Endocrinology (1997) 2.49
Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive. Nat Med (2003) 2.40
Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic mice. J Immunol (2001) 2.39
Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice. J Exp Med (2002) 2.02
Processing of engulfed apoptotic bodies yields T cell epitopes. J Immunol (1997) 1.97
Genetic control of diabetes progression. Immunity (1997) 1.95
Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes? Diabetes (2000) 1.92
S-nitrosylation regulates apoptosis. Nature (1997) 1.91
Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry? Nat Immunol (2001) 1.79
Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells. Immunity (2002) 1.78
Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes. J Exp Med (2002) 1.58
Islet-specific T-cell clones from the NOD mouse respond to beta-granule antigen. Diabetes (1994) 1.45
Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities. J Exp Med (1998) 1.44
Ontogeny of T cell tolerance to peripherally expressed antigens. Proc Natl Acad Sci U S A (1999) 1.43
In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes. J Immunol (2002) 1.30
Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced. Diabetes (2002) 1.20
Inhibition of caspase activity induces a switch from apoptosis to necrosis. FEBS Lett (1998) 1.19
Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor. Endocrinology (1998) 1.14
Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes. J Immunol (2001) 1.13
Cellular and molecular changes accompanying the progression from insulitis to diabetes. Eur J Immunol (1999) 1.12
Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells. J Immunol (2002) 1.01
Intolerable secretion in tolerant transgenic mice. Nature (1988) 0.97
The immune response to islets in experimental diabetes and insulin-dependent diabetes mellitus. Curr Opin Immunol (1996) 0.97
Blockade of caspases inhibits amebic liver abscess formation in a mouse model of disease. Infect Immun (2001) 0.97
Autoimmune diabetes: the involvement of benign and malignant autoimmunity. J Autoimmun (1999) 0.94
Apoptosis and antiphospholipid antibodies. Semin Arthritis Rheum (1998) 0.87
Constitutive, but not inflammatory, cross-presentation is disabled in the pancreas of young mice. Eur J Immunol (2002) 0.86
Projection of an immunological self shadow within the thymus by the aire protein. Science (2002) 12.15
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med (2009) 9.71
FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell (2006) 9.24
Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity (2010) 8.90
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J Exp Med (2008) 6.07
Gut immune maturation depends on colonization with a host-specific microbiota. Cell (2012) 5.91
Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science (2002) 5.82
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity (2007) 5.67
Arthritis critically dependent on innate immune system players. Immunity (2002) 5.31
Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J Exp Med (2002) 5.09
Stability of the regulatory T cell lineage in vivo. Science (2010) 4.89
The cellular mechanism of Aire control of T cell tolerance. Immunity (2005) 4.74
Aire. Annu Rev Immunol (2009) 4.43
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature (2012) 4.31
Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nat Immunol (2009) 4.07
CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med (2004) 3.57
Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proc Natl Acad Sci U S A (2011) 3.55
Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells. J Immunol (2007) 3.47
Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells. Immunity (2008) 3.25
How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease. Nat Immunol (2002) 3.20
Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response. J Exp Med (2005) 3.14
A special population of regulatory T cells potentiates muscle repair. Cell (2013) 3.09
A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity (2005) 3.07
Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis. J Exp Med (2002) 2.98
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. J Exp Med (2004) 2.92
Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity. Immunity (2011) 2.87
Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire. J Exp Med (2007) 2.84
Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci U S A (2006) 2.83
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science (2014) 2.77
Aire's partners in the molecular control of immunological tolerance. Cell (2010) 2.68
Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells. Nat Immunol (2004) 2.68
Where CD4+CD25+ T reg cells impinge on autoimmune diabetes. J Exp Med (2005) 2.61
A decade of AIRE. Nat Rev Immunol (2007) 2.45
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nat Genet (2007) 2.39
Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science (2006) 2.38
Genomic definition of multiple ex vivo regulatory T cell subphenotypes. Proc Natl Acad Sci U S A (2010) 2.30
How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets. Immunity (2009) 2.15
TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic islets. J Exp Med (2007) 2.15
Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol (2013) 2.13
Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol (2006) 2.12
Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging. Nat Immunol (2012) 2.11
Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice. Cancer Cell (2003) 2.11
Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis. Proc Natl Acad Sci U S A (2010) 2.09
Modifier loci condition autoimmunity provoked by Aire deficiency. J Exp Med (2005) 2.08
Endocrine self and gut non-self intersect in the pancreatic lymph nodes. Proc Natl Acad Sci U S A (2005) 2.06
Effects of CB-VEGF-A injection in rat flap models for improved survival. Plast Reconstr Surg (2013) 1.99
Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity. Proc Natl Acad Sci U S A (2004) 1.96
Arthritogenic monoclonal antibodies from K/BxN mice. J Exp Med (2002) 1.94
Conservation and divergence in the transcriptional programs of the human and mouse immune systems. Proc Natl Acad Sci U S A (2013) 1.94
Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. J Clin Invest (2010) 1.93
Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy. Am J Pathol (2008) 1.93
A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol (2012) 1.93
Back to central tolerance. Immunity (2004) 1.88
The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci U S A (2008) 1.85