PubRank

Danny Reinberg

Author PubWeight™ 341.18‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev 2002 13.08
2 The Polycomb complex PRC2 and its mark in life. Nature 2011 11.97
3 Elongation by RNA polymerase II: the short and long of it. Genes Dev 2004 9.17
4 A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 2004 8.66
5 A unified theory of gene expression. Cell 2002 7.61
6 Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science 2007 7.41
7 Suz12 binds to silenced regions of the genome in a cell-type-specific manner. Genome Res 2006 6.75
8 Role of the polycomb protein EED in the propagation of repressive histone marks. Nature 2009 6.62
9 Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27. Genes Dev 2004 6.19
10 Histones: annotating chromatin. Annu Rev Genet 2009 5.93
11 FACT facilitates transcription-dependent nucleosome alteration. Science 2003 5.83
12 Epigenetic dynamics of imprinted X inactivation during early mouse development. Science 2003 5.80
13 Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Mol Cell 2007 5.78
14 Regulation of p53 activity through lysine methylation. Nature 2004 5.78
15 PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. Mol Cell 2002 5.59
16 Histone lysine methylation: a signature for chromatin function. Trends Genet 2003 5.55
17 Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev 2002 5.43
18 Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol Cell 2004 5.37
19 New nomenclature for chromatin-modifying enzymes. Cell 2007 5.34
20 Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell 2006 5.14
21 Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3. Mol Cell 2004 5.06
22 The key to development: interpreting the histone code? Curr Opin Genet Dev 2005 4.96
23 Molecular signals of epigenetic states. Science 2010 4.81
24 Jarid2 and PRC2, partners in regulating gene expression. Genes Dev 2010 4.65
25 Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proc Natl Acad Sci U S A 2005 4.57
26 Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms. Mol Cell 2008 4.44
27 Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. J Biol Chem 2005 4.20
28 Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Mol Cell 2005 4.04
29 Chromatin structure and the inheritance of epigenetic information. Nat Rev Genet 2010 4.03
30 Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylation. Cell 2003 3.82
31 L3MBTL1, a histone-methylation-dependent chromatin lock. Cell 2007 3.70
32 Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. Genes Dev 2010 3.49
33 Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes. Genes Dev 2002 3.37
34 PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. Mol Cell 2012 3.28
35 Tracking FACT and the RNA polymerase II elongation complex through chromatin in vivo. Science 2003 3.22
36 SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes Dev 2006 3.12
37 Polycomb group protein ezh2 controls actin polymerization and cell signaling. Cell 2005 3.01
38 Facultative heterochromatin: is there a distinctive molecular signature? Mol Cell 2007 2.94
39 Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo. Mol Cell Biol 2008 2.93
40 Histone H3 Lys 4 methylation: caught in a bind? Genes Dev 2006 2.86
41 Asymmetrically modified nucleosomes. Cell 2012 2.79
42 A double take on bivalent promoters. Genes Dev 2013 2.79
43 Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator. Science 2010 2.78
44 SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. Genes Dev 2007 2.77
45 SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature 2007 2.76
46 The human PAF complex coordinates transcription with events downstream of RNA synthesis. Genes Dev 2005 2.70
47 Is there a code embedded in proteins that is based on post-translational modifications? Nat Rev Mol Cell Biol 2008 2.64
48 G9a and Glp methylate lysine 373 in the tumor suppressor p53. J Biol Chem 2010 2.64
49 Histone lysine demethylases and their impact on epigenetics. Cell 2006 2.54
50 PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis. Genes Dev 2005 2.51
51 Specificity and mechanism of the histone methyltransferase Pr-Set7. Genes Dev 2005 2.50
52 Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator. Curr Biol 2012 2.50
53 Histone variants meet their match. Nat Rev Mol Cell Biol 2005 2.47
54 Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development. Mol Cell Biol 2009 2.47
55 PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Mol Cell 2005 2.44
56 Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome. Mol Cell Biol 2004 2.43
57 Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage. Mol Cell 2010 2.39
58 A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell 2004 2.27
59 Drosophila Paf1 modulates chromatin structure at actively transcribed genes. Mol Cell Biol 2006 2.16
60 Chromatin higher-order structures and gene regulation. Curr Opin Genet Dev 2011 2.08
61 The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate. J Biol Chem 2009 2.06
62 Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. J Biol Chem 2009 2.02
63 The constantly changing face of chromatin. Sci Aging Knowledge Environ 2003 2.02
64 Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II. Proc Natl Acad Sci U S A 2004 2.01
65 PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells. Nat Struct Mol Biol 2013 2.01
66 Recent highlights of RNA-polymerase-II-mediated transcription. Curr Opin Cell Biol 2004 1.91
67 PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription. Genes Dev 2012 1.81
68 Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity. Cell 2012 1.78
69 Human Elongator facilitates RNA polymerase II transcription through chromatin. Proc Natl Acad Sci U S A 2002 1.75
70 Methylation-acetylation interplay activates p53 in response to DNA damage. Mol Cell Biol 2007 1.75
71 The program for processing newly synthesized histones H3.1 and H4. Nat Struct Mol Biol 2010 1.71
72 CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53. Genes Dev 2014 1.62
73 Functional analysis of the subunits of the chromatin assembly factor RSF. Mol Cell Biol 2003 1.56
74 Functional characterization of core promoter elements: DPE-specific transcription requires the protein kinase CK2 and the PC4 coactivator. Mol Cell 2005 1.52
75 MBT domain proteins in development and disease. Semin Cell Dev Biol 2009 1.49
76 Functional characterization of core promoter elements: the downstream core element is recognized by TAF1. Mol Cell Biol 2005 1.46
77 Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality. Genome Res 2013 1.45
78 Calorie restriction and the exercise of chromatin. Genes Dev 2009 1.44
79 A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes Dev 2011 1.43
80 The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation. J Biol Chem 2010 1.41
81 The mediator coactivator complex: functional and physical roles in transcriptional regulation. J Cell Sci 2003 1.41
82 Facts about FACT and transcript elongation through chromatin. Curr Opin Genet Dev 2004 1.40
83 Human Spt6 stimulates transcription elongation by RNA polymerase II in vitro. Mol Cell Biol 2004 1.38
84 ASAP, a novel protein complex involved in RNA processing and apoptosis. Mol Cell Biol 2003 1.34
85 L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure. Mol Cell 2011 1.32
86 Histone chaperone FACT action during transcription through chromatin by RNA polymerase II. Proc Natl Acad Sci U S A 2013 1.32
87 Methods and tips for the purification of human histone methyltransferases. Methods 2003 1.31
88 Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo. J Biol Chem 2009 1.28
89 Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding. PLoS Genet 2012 1.27
90 FCP1, a phosphatase specific for the heptapeptide repeat of the largest subunit of RNA polymerase II, stimulates transcription elongation. Mol Cell Biol 2002 1.26
91 The role of PR-Set7 in replication licensing depends on Suv4-20h. Genes Dev 2012 1.22
92 Facile synthesis of site-specifically acetylated and methylated histone proteins: reagents for evaluation of the histone code hypothesis. Proc Natl Acad Sci U S A 2003 1.20
93 Epigenetic inheritance: uncontested? Cell Res 2011 1.19
94 Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4. Genes Dev 2012 1.19
95 Transcription through chromatin: understanding a complex FACT. Biochim Biophys Acta 2004 1.15
96 SIRT3 functions in the nucleus in the control of stress-related gene expression. Mol Cell Biol 2012 1.12
97 Processing the H3K36me3 signature. Nat Genet 2009 1.10
98 Highly compacted chromatin formed in vitro reflects the dynamics of transcription activation in vivo. Mol Cell 2010 1.08
99 Beyond histone methyl-lysine binding: how malignant brain tumor (MBT) protein L3MBTL1 impacts chromatin structure. Cell Cycle 2008 1.08
100 EZH2 couples pancreatic regeneration to neoplastic progression. Genes Dev 2012 1.07
101 New chaps in the histone chaperone arena. Genes Dev 2010 1.06
102 Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin. Genes Dev 2013 1.04
103 Histone deposition and chromatin assembly by RSF. Methods 2003 1.03
104 Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome. Elife 2013 1.00
105 Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1. Science 2002 0.99
106 Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30. PLoS One 2012 0.99
107 A chromatin link to caste identity in the carpenter ant Camponotus floridanus. Genome Res 2012 0.99
108 Tips in analyzing antibodies directed against specific histone tail modifications. Methods Enzymol 2004 0.98
109 SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors. Genes Dev 2013 0.97
110 Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication. Science 2014 0.97
111 From chromatin to cancer: a new histone lysine methyltransferase enters the mix. Nat Cell Biol 2004 0.96
112 Histone tails: ideal motifs for probing epigenetics through chemical biology approaches. Chembiochem 2010 0.95
113 Techniques used to study transcription on chromatin templates. Methods Enzymol 2004 0.87
114 BRD4 jump-starts transcription after mitotic silencing. Genome Biol 2011 0.86
115 DNA methylation in social insects: how epigenetics can control behavior and longevity. Annu Rev Entomol 2014 0.85
116 The C-terminal domain phosphatase and transcription elongation activities of FCP1 are regulated by phosphorylation. Proc Natl Acad Sci U S A 2003 0.85
117 Fcp1 dephosphorylation of the RNA polymerase II C-terminal domain is required for efficient transcription of heat shock genes. Mol Cell Biol 2012 0.83
118 Methods to identify and functionally analyze factors that specifically recognize histone lysine methylation. Methods 2006 0.83
119 Epigenome editing. Nat Biotechnol 2013 0.82
120 Stem cells: Escaping fates with open states. Nature 2009 0.80
121 Promoter activation when the ChIPs are down. Nat Struct Mol Biol 2006 0.79
122 Nonradioactive, ultrasensitive site-specific protein-protein photocrosslinking: interactions of alpha-helix 2 of TATA-binding protein with general transcription factor TFIIA and transcriptional repressor NC2. Nucleic Acids Res 2008 0.78
123 Putting a halt on PRC2 in pediatric glioblastoma. Nat Genet 2013 0.77
124 A gateway to study protein lysine methylation. Nat Chem Biol 2008 0.77
125 The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression. J Clin Invest 2017 0.75
126 Corrigendum: CTCF-mediated topological boundaries during development foster appropriate gene regulation. Genes Dev 2017 0.75