Effects of controlled RAD52 expression on repair and recombination in Saccharomyces cerevisiae.

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Published in Mol Cell Biol on April 01, 1991

Authors

K J Dornfeld1, D M Livingston

Author Affiliations

1: Department of Biochemistry, University of Minnesota, Minneapolis 55455.

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Biological and biochemical studies of cells transformed by simian virus 40 temperature-sensitive gene A mutants and A mutant revertants. J Virol (1977) 1.64

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