Published in Genes Dev on January 15, 2010
Signals to promote myelin formation and repair. Nat Rev Neurol (2010) 1.95
MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. PLoS Biol (2013) 1.45
Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Neuron (2012) 1.18
Central nervous system dysfunction in a mouse model of FA2H deficiency. Glia (2011) 1.05
Intrinsic and extrinsic control of oligodendrocyte development. Curr Opin Neurobiol (2013) 1.01
Fine-Tuning Oligodendrocyte Development by microRNAs. Front Neurosci (2012) 0.89
Novel endogenous angiogenesis inhibitors and their therapeutic potential. Acta Pharmacol Sin (2015) 0.87
Zfp488 promotes oligodendrocyte differentiation of neural progenitor cells in adult mice after demyelination. Sci Rep (2011) 0.86
New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development. BMC Neurosci (2014) 0.84
TGFβ signaling regulates the timing of CNS myelination by modulating oligodendrocyte progenitor cell cycle exit through SMAD3/4/FoxO1/Sp1. J Neurosci (2014) 0.83
Tcf7l2 is tightly controlled during myelin formation. Cell Mol Neurobiol (2011) 0.82
Interplay between transcriptional control and chromatin regulation in the oligodendrocyte lineage. Glia (2015) 0.80
The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS. Cell Death Dis (2015) 0.78
Regulation of the timing of oligodendrocyte differentiation: mechanisms and perspectives. Neurosci Bull (2013) 0.78
The endogenous zinc finger transcription factor, ZNF24, modulates the angiogenic potential of human microvascular endothelial cells. FASEB J (2014) 0.78
Identification of a functional nuclear localization signal mediating nuclear import of the zinc finger transcription factor ZNF24. PLoS One (2013) 0.77
Transcriptional Fingerprint of Hypomyelination in Zfp191null and Shiverer (Mbpshi) Mice. ASN Neuro (2016) 0.75
A zinc finger protein that regulates oligodendrocyte specification, migration and myelination in zebrafish. Development (2015) 0.75
DNA methylation in oligodendroglial cells during developmental myelination and in disease. Neurogenesis (Austin) (2017) 0.75
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci (2008) 17.27
Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. Proc Natl Acad Sci U S A (1997) 7.42
Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell (2002) 5.64
Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiol Rev (2001) 5.50
Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nat Genet (2003) 5.43
The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell (2002) 5.35
Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med (2002) 3.68
Notch receptor activation inhibits oligodendrocyte differentiation. Neuron (1998) 3.30
Long-range disruption of gene expression by a selectable marker cassette. Proc Natl Acad Sci U S A (1996) 2.83
Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain (2008) 2.83
Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system. Neuron (2008) 2.74
Functional genomic analysis of oligodendrocyte differentiation. J Neurosci (2006) 2.64
Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Development (2001) 2.43
BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin. Nat Genet (1999) 2.40
Oligodendrocyte wars. Nat Rev Neurosci (2006) 2.39
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron (2007) 2.38
Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice. J Neurosci (2005) 2.27
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell (2009) 2.18
A role for the helix-loop-helix protein Id2 in the control of oligodendrocyte development. Neuron (2001) 1.92
The Id4 HLH protein and the timing of oligodendrocyte differentiation. EMBO J (2000) 1.79
The chemokine receptor CXCR2 controls positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. Cell (2002) 1.73
Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma. J Cell Biol (2005) 1.69
Further observations on hippocampal neurons in dispersed cell culture. J Comp Neurol (1979) 1.59
Olig1 and Sox10 interact synergistically to drive myelin basic protein transcription in oligodendrocytes. J Neurosci (2007) 1.58
Quantitative effects on gene silencing by allelic variation at a tetranucleotide microsatellite. Hum Mol Genet (2001) 1.54
A matter of identity: transcriptional control in oligodendrocytes. J Mol Neurosci (2007) 1.47
An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development (2006) 1.43
Mzf1 controls cell proliferation and tumorigenesis. Genes Dev (2001) 1.43
The SCAN domain family of zinc finger transcription factors. Gene (2005) 1.34
Identification of a novel oligodendrocyte cell adhesion protein using gene expression profiling. J Neurosci (2006) 1.32
Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex. Nat Neurosci (2001) 1.26
Nur7 is a nonsense mutation in the mouse aspartoacylase gene that causes spongy degeneration of the CNS. J Neurosci (2008) 1.23
Isolation and characterization of immature oligodendrocyte lineage cells. Methods (1998) 1.21
Current concepts of PLP and its role in the nervous system. Microsc Res Tech (1998) 1.17
The SCAN domain defines a large family of zinc finger transcription factors. Gene (2003) 1.10
The SCAN domain mediates selective oligomerization. J Biol Chem (2000) 1.10
Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal. Development (2003) 0.98
The SCAN domain of ZNF174 is a dimer. J Biol Chem (2001) 0.94
Structure of the SCAN domain from the tumor suppressor protein MZF1. J Mol Biol (2006) 0.92
The zinc finger transcription factor 191 is required for early embryonic development and cell proliferation. Exp Cell Res (2006) 0.90
Zinc finger protein 191 (ZNF191/Zfp191) is necessary to maintain neural cells as cycling progenitors. Stem Cells (2009) 0.88
Expression of the transcription factor Zfp191 during embryonic development in the mouse. Gene Expr Patterns (2007) 0.86
Characterization of the target DNA sequence for the DNA-binding domain of zinc finger protein 191. Acta Biochim Biophys Sin (Shanghai) (2008) 0.81
Isolation, cloning, and expression of a new murine zinc finger encoding gene. Biochim Biophys Acta (1999) 0.81
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci (2008) 17.27
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell (2003) 15.12
Projection of an immunological self shadow within the thymus by the aire protein. Science (2002) 12.15
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A (2003) 9.14
The classical complement cascade mediates CNS synapse elimination. Cell (2007) 9.06
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell (2006) 8.48
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis. Cell (2005) 7.41
Telomere dysfunction induces metabolic and mitochondrial compromise. Nature (2011) 6.36
The differential effects of mutant p53 alleles on advanced murine lung cancer. Cancer Res (2005) 5.93
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron (2012) 5.84
Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature (2010) 5.47
Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. Cancer Cell (2005) 4.14
Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A (2004) 3.74
Genomic analysis of reactive astrogliosis. J Neurosci (2012) 3.62
Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells. Science (2002) 3.54
High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene. Cancer Cell (2004) 3.46
Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis. Cell (2009) 3.46
Architecture and activity-mediated refinement of axonal projections from a mosaic of genetically identified retinal ganglion cells. Neuron (2008) 3.41
Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron (2010) 3.37
NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes. Neuron (2004) 3.24
Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis. Proc Natl Acad Sci U S A (2009) 3.17
Genetic identification of an On-Off direction-selective retinal ganglion cell subtype reveals a layer-specific subcortical map of posterior motion. Neuron (2009) 3.13
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain. Science (2014) 3.11
Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins. Mol Ther (2011) 3.10
Stage-specific sensitivity to p53 restoration during lung cancer progression. Nature (2010) 3.03
Regulation of synaptic connectivity by glia. Nature (2010) 3.02
Microglia: scapegoat, saboteur, or something else? Science (2013) 2.94
Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta. Cell Metab (2006) 2.82
Neuroscience: Glia - more than just brain glue. Nature (2009) 2.76
Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system. Neuron (2008) 2.74
Why is Wallerian degeneration in the CNS so slow? Annu Rev Neurosci (2007) 2.70
NS21: re-defined and modified supplement B27 for neuronal cultures. J Neurosci Methods (2008) 2.68
Astrocyte heterogeneity: an underappreciated topic in neurobiology. Curr Opin Neurobiol (2010) 2.68
Functional genomic analysis of oligodendrocyte differentiation. J Neurosci (2006) 2.64
Generation of oligodendroglial cells by direct lineage conversion. Nat Biotechnol (2013) 2.64
Signaling between glia and neurons: focus on synaptic plasticity. Curr Opin Neurobiol (2005) 2.62
Constitutively active Akt induces enhanced myelination in the CNS. J Neurosci (2008) 2.60
The complement system: an unexpected role in synaptic pruning during development and disease. Annu Rev Neurosci (2012) 2.53
Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer. Prostate (2004) 2.49
Emerging roles of astrocytes in neural circuit development. Nat Rev Neurosci (2013) 2.45
Retinal ganglion cells do not extend axons by default: promotion by neurotrophic signaling and electrical activity. Neuron (2002) 2.41
Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes. Proc Natl Acad Sci U S A (2002) 2.28
Astrocytes and disease: a neurodevelopmental perspective. Genes Dev (2012) 2.28
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. Nature (2003) 2.28
Axon degeneration: molecular mechanisms of a self-destruction pathway. J Cell Biol (2012) 2.26
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. J Clin Invest (2011) 2.25
Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene. J Neurosci (2007) 2.23
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell (2009) 2.18
Role for glia in synaptogenesis. Glia (2004) 2.15
TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity. Proc Natl Acad Sci U S A (2009) 2.13
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse. EMBO J (2008) 2.08
Modifier loci condition autoimmunity provoked by Aire deficiency. J Exp Med (2005) 2.08
Inducible site-specific recombination in myelinating cells. Genesis (2003) 2.07
The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells. PLoS One (2010) 2.06
Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina. Neuron (2005) 2.06
Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus. J Clin Invest (2016) 2.06
Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2. Proc Natl Acad Sci U S A (2002) 2.04
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility. EMBO J (2003) 1.98
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc Natl Acad Sci U S A (2008) 1.98
Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor. J Biol Chem (2002) 1.95
Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope. J Exp Med (2011) 1.94
Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity. EMBO J (2009) 1.94
An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. J Exp Med (2006) 1.94
Development of a method for the purification and culture of rodent astrocytes. Neuron (2011) 1.92
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors. Nature (2012) 1.92
Endogenous T cell responses to antigens expressed in lung adenocarcinomas delay malignant tumor progression. Cancer Cell (2011) 1.89
Between the sheets: a molecular sieve makes myelin membranes. Dev Cell (2011) 1.87
TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex. Mol Cell Biol (2007) 1.86
Know thy mouse. Trends Genet (2006) 1.86
Importance of intrinsic mechanisms in cell fate decisions in the developing rat retina. Neuron (2003) 1.86
Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation. J Clin Invest (2011) 1.84
The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis. Genes Dev (2006) 1.79
Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress. Brain (2006) 1.78
Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells. Cancer Res (2008) 1.77
Transgenic mice reveal unexpected diversity of on-off direction-selective retinal ganglion cell subtypes and brain structures involved in motion processing. J Neurosci (2011) 1.77
Endoplasmic reticulum stress in disorders of myelinating cells. Nat Neurosci (2009) 1.76
The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage. J Clin Invest (2007) 1.74
Neuronal pentraxins mediate synaptic refinement in the developing visual system. J Neurosci (2006) 1.71
Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma. J Cell Biol (2005) 1.69
Paranodal junction formation and spermatogenesis require sulfoglycolipids. Proc Natl Acad Sci U S A (2002) 1.68
Cadherin-6 mediates axon-target matching in a non-image-forming visual circuit. Neuron (2011) 1.67
Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC. Proc Natl Acad Sci U S A (2011) 1.65
Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23. EMBO J (2004) 1.63
Synergy between PPARgamma ligands and platinum-based drugs in cancer. Cancer Cell (2007) 1.60
Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke. J Cereb Blood Flow Metab (2008) 1.59
LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival. Nat Med (2002) 1.57
The mouse as a model for understanding chronic diseases of aging: the histopathologic basis of aging in inbred mice. Pathobiol Aging Age Relat Dis (2011) 1.56
Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development. Oncogene (2003) 1.56
PAK4 kinase is essential for embryonic viability and for proper neuronal development. Mol Cell Biol (2003) 1.55
Mouse model of subretinal neovascularization with choroidal anastomosis. Retina (2003) 1.52
A myelin galactolipid, sulfatide, is essential for maintenance of ion channels on myelinated axon but not essential for initial cluster formation. J Neurosci (2002) 1.51
Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes. Sci Transl Med (2012) 1.49
Glucosinolate and amino acid biosynthesis in Arabidopsis. Plant Physiol (2004) 1.47
Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. Cancer Discov (2011) 1.46
MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. PLoS Biol (2013) 1.45