Published in Am J Hum Genet on January 01, 2010
Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Transethnic meta-analysis of genomewide association studies. Genet Epidemiol (2011) 2.53
New approaches to disease mapping in admixed populations. Nat Rev Genet (2011) 2.22
Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet (2011) 1.94
Integrating functional data to prioritize causal variants in statistical fine-mapping studies. PLoS Genet (2014) 1.91
Integrative approaches for large-scale transcriptome-wide association studies. Nat Genet (2016) 1.90
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75
Ancestry-shift refinement mapping of the C6orf97-ESR1 breast cancer susceptibility locus. PLoS Genet (2010) 1.74
Identifying causal variants at loci with multiple signals of association. Genetics (2014) 1.41
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. Genes Brain Behav (2010) 1.35
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol (2012) 1.34
High trans-ethnic replicability of GWAS results implies common causal variants. PLoS Genet (2013) 1.32
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics (2014) 1.31
Intersection of population variation and autoimmunity genetics in human T cell activation. Science (2014) 1.27
Multiethnic genetic association studies improve power for locus discovery. PLoS One (2010) 1.23
An optimal weighted aggregated association test for identification of rare variants involved in common diseases. Genetics (2011) 1.21
Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies. Am J Hum Genet (2015) 1.03
Progress and promise in understanding the genetic basis of common diseases. Proc Biol Sci (2015) 1.02
Trans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations. Genome Med (2014) 1.02
Re-ranking sequencing variants in the post-GWAS era for accurate causal variant identification. PLoS Genet (2013) 1.00
Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Lancet Neurol (2015) 0.98
Identification of causal genes for complex traits. Bioinformatics (2015) 0.94
Dissecting the causal genetic mechanisms of coronary heart disease. Curr Atheroscler Rep (2014) 0.93
Exploring genetic susceptibility to cancer in diverse populations. Curr Opin Genet Dev (2010) 0.93
Fine-mapping of genome-wide association study-identified risk loci for colorectal cancer in African Americans. Hum Mol Genet (2013) 0.92
Trans-ethnic study design approaches for fine-mapping. Eur J Hum Genet (2016) 0.89
Genetic variations in colorectal cancer risk and clinical outcome. World J Gastroenterol (2014) 0.86
Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions. Hum Mol Genet (2015) 0.85
Power of single- vs. multi-marker tests of association. Genet Epidemiol (2012) 0.85
Catecholamine pathway gene variation is associated with norepinephrine and epinephrine concentrations at rest and after exercise. Pharmacogenet Genomics (2012) 0.84
Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine. Circ Cardiovasc Genet (2011) 0.84
Multiple testing correction in linear mixed models. Genome Biol (2016) 0.84
Determining causality and consequence of expression quantitative trait loci. Hum Genet (2014) 0.84
Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome. Crit Care (2016) 0.83
Colocalization of GWAS and eQTL Signals Detects Target Genes. Am J Hum Genet (2016) 0.81
Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. Eur J Hum Genet (2016) 0.81
Transethnic replication of association of CTG18.1 repeat expansion of TCF4 gene with Fuchs' corneal dystrophy in Chinese implies common causal variant. Invest Ophthalmol Vis Sci (2014) 0.81
Comparison of genome-wide association methods in analyses of admixed populations with complex familial relationships. PLoS One (2014) 0.81
Fine mapping of type 2 diabetes susceptibility loci. Curr Diab Rep (2014) 0.81
Genetic risk score for prediction of newborn adiposity and large-for-gestational-age birth. J Clin Endocrinol Metab (2014) 0.81
Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet (2016) 0.81
Atrial Fibrillation and Race - A Contemporary Review. Curr Cardiovasc Risk Rep (2013) 0.80
Dissecting the genetics of complex traits using summary association statistics. Nat Rev Genet (2016) 0.80
Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations. Am J Hum Genet (2017) 0.79
Matrix gla protein gene polymorphism is associated with increased coronary artery calcification progression. Arterioscler Thromb Vasc Biol (2013) 0.79
Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. Hum Mol Genet (2015) 0.78
Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise. Physiol Genomics (2015) 0.77
Meta-Analysis of Rare Variant Association Tests in Multiethnic Populations. Genet Epidemiol (2015) 0.77
Systematic fine-mapping of association with BMI and type 2 diabetes at the FTO locus by integrating results from multiple ethnic groups. PLoS One (2014) 0.76
Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities. Breast Cancer Res (2016) 0.75
Pure and Confounded Effects of Causal SNPs on Longevity: Insights for Proper Interpretation of Research Findings in GWAS of Populations with Different Genetic Structures. Front Genet (2016) 0.75
Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology. PLoS Genet (2017) 0.75
A haplotype map of the human genome. Nature (2005) 105.70
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data. Genetics (2003) 17.73
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet (2006) 17.36
Linkage disequilibrium in humans: models and data. Am J Hum Genet (2001) 14.97
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet (2009) 8.44
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2008) 7.65
Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip. PLoS Genet (2009) 6.61
So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests. Am J Hum Genet (2007) 6.26
1000 Genomes project. Nat Biotechnol (2008) 5.73
'Racial' differences in genetic effects for complex diseases. Nat Genet (2004) 5.15
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Proc Natl Acad Sci U S A (2008) 4.76
Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls. Hum Genet (2007) 3.92
FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation. Hum Mol Genet (2009) 2.62
Rapid and accurate multiple testing correction and power estimation for millions of correlated markers. PLoS Genet (2009) 2.30
Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants. Genome Res (2005) 1.25
Linkage effects and analysis of finite sample errors in the HapMap. Hum Hered (2009) 0.96
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet (2006) 12.45
Identifying personal genomes by surname inference. Science (2013) 10.79
The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med (2003) 7.94
Estimating local ancestry in admixed populations. Am J Hum Genet (2008) 5.90
Categorization of humans in biomedical research: genes, race and disease. Genome Biol (2002) 4.84
Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene. PLoS Genet (2009) 3.60
Leveraging the HapMap correlation structure in association studies. Am J Hum Genet (2007) 3.57
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health (2005) 3.50
Genetic ancestry in lung-function predictions. N Engl J Med (2010) 3.30
Population stratification confounds genetic association studies among Latinos. Hum Genet (2005) 3.19
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal. Cell Cycle (2011) 3.11
Admixture mapping of white cell count: genetic locus responsible for lower white blood cell count in the Health ABC and Jackson Heart studies. Am J Hum Genet (2008) 3.06
Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol (2005) 3.03
Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels. Am J Hum Genet (2007) 2.91
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell (2009) 2.79
Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma. Nat Genet (2009) 2.73
Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am J Respir Crit Care Med (2004) 2.62
Genomic privacy and limits of individual detection in a pool. Nat Genet (2009) 2.60
Inference of locus-specific ancestry in closely related populations. Bioinformatics (2009) 2.54
Mammographic breast density and the Gail model for breast cancer risk prediction in a screening population. Breast Cancer Res Treat (2005) 2.53
CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues. Cancer Discov (2012) 2.51
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45
Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet (2005) 2.41
Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma. Am J Respir Crit Care Med (2003) 2.39
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32. Nat Genet (2010) 2.37
PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genet (2007) 2.36
Prevention of breast cancer in postmenopausal women: approaches to estimating and reducing risk. J Natl Cancer Inst (2009) 2.35
Fast and accurate inference of local ancestry in Latino populations. Bioinformatics (2012) 2.30
Comparing genetic ancestry and self-described race in african americans born in the United States and in Africa. Cancer Epidemiol Biomarkers Prev (2008) 2.29
On the inference of ancestries in admixed populations. Genome Res (2008) 2.27
Are breast density and bone mineral density independent risk factors for breast cancer? J Natl Cancer Inst (2005) 2.21
Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations. Hum Genet (2005) 2.19
A model-based approach for analysis of spatial structure in genetic data. Nat Genet (2012) 2.02
The genetics of human longevity. Am J Med (2004) 1.97
Efficient reconstruction of haplotype structure via perfect phylogeny. J Bioinform Comput Biol (2003) 1.96
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet (2011) 1.92
Genetic ancestry, population sub-structure, and cardiovascular disease-related traits among African-American participants in the CARDIA Study. Hum Genet (2007) 1.91
Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region. Hum Genet (2008) 1.81
Ancestry-related assortative mating in Latino populations. Genome Biol (2009) 1.79
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet (2012) 1.77
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas. PLoS Genet (2012) 1.74
A randomization test for controlling population stratification in whole-genome association studies. Am J Hum Genet (2007) 1.73
Accurate estimation of expression levels of homologous genes in RNA-seq experiments. J Comput Biol (2011) 1.69
Genotype is a stronger determinant than sex of the mouse gut microbiota. Microb Ecol (2010) 1.63
Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean. Br J Haematol (2008) 1.61
Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma. PLoS One (2008) 1.61
Genetic ancestry and risk of breast cancer among U.S. Latinas. Cancer Res (2008) 1.58
Genotype error detection using Hidden Markov Models of haplotype diversity. J Comput Biol (2008) 1.57
Tracing sub-structure in the European American population with PCA-informative markers. PLoS Genet (2008) 1.56
A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. PLoS Genet (2012) 1.53
History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One (2011) 1.50
ADAM33 is not associated with asthma in Puerto Rican or Mexican populations. Am J Respir Crit Care Med (2003) 1.47
Genetic determinants of serum testosterone concentrations in men. PLoS Genet (2011) 1.45
Ancestry-environment interactions and asthma risk among Puerto Ricans. Am J Respir Crit Care Med (2006) 1.42
miRNAkey: a software for microRNA deep sequencing analysis. Bioinformatics (2010) 1.41
Probabilistic inference of viral quasispecies subject to recombination. J Comput Biol (2013) 1.40
European ancestry is positively associated with breast cancer risk in Mexican women. Cancer Epidemiol Biomarkers Prev (2010) 1.37
CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma. Am J Respir Crit Care Med (2005) 1.34
Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations. Hum Genet (2005) 1.27
Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. Blood (2012) 1.26
A generic coalescent-based framework for the selection of a reference panel for imputation. Genet Epidemiol (2010) 1.26
Genetic admixture, adipocytokines, and adiposity in Black Americans: the Health, Aging, and Body Composition study. Hum Genet (2007) 1.25
Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma. Pharmacogenet Genomics (2009) 1.24
An admixture scan in 1,484 African American women with breast cancer. Cancer Epidemiol Biomarkers Prev (2009) 1.22
Dissecting complex diseases in complex populations: asthma in latino americans. Proc Am Thorac Soc (2007) 1.21
Heterogeneity in genetic admixture across different regions of Argentina. PLoS One (2012) 1.20
A New Stress-Based Model of Political Extremism: Personal Exposure to Terrorism, Psychological Distress, and Exclusionist Political Attitudes. J Conflict Resolut (2009) 1.17
Highly scalable genotype phasing by entropy minimization. IEEE/ACM Trans Comput Biol Bioinform (2008) 1.14
A review of cancer in U.S. Hispanic populations. Cancer Prev Res (Phila) (2012) 1.11
Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics (2013) 1.11
Matrin 3 binds and stabilizes mRNA. PLoS One (2011) 1.11
Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas. Hum Mol Genet (2012) 1.11
Moderate-intensity physical activity ameliorates the breast cancer risk in diabetic women. Diabetes Care (2012) 1.06
Inference and analysis of haplotypes from combined genotyping studies deposited in dbSNP. Genome Res (2005) 1.05
The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Chest (2011) 1.02
African ancestry, socioeconomic status, and kidney function in elderly African Americans: a genetic admixture analysis. J Am Soc Nephrol (2006) 1.02
Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study. Atherosclerosis (2007) 1.01
Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults. Exp Gerontol (2009) 1.00
Estrogen receptor alpha haplotypes and breast cancer risk in older Caucasian women. Breast Cancer Res Treat (2007) 0.99
HAPLOPOOL: improving haplotype frequency estimation through DNA pools and phylogenetic modeling. Bioinformatics (2007) 0.98
Clinical and biomarker predictors of side effects from tamoxifen. Breast Cancer Res Treat (2011) 0.98
Serum insulin-like growth factor-1 binding proteins 1 and 2 and mortality in older adults: the Health, Aging, and Body Composition Study. J Am Geriatr Soc (2009) 0.98
Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. Hum Mol Genet (2013) 0.97
Dynamic network topology changes in functional modules predict responses to oxidative stress in yeast. Mol Biosyst (2009) 0.96
Genetic ancestry modifies the association between genetic risk variants and breast cancer risk among Hispanic and non-Hispanic white women. Carcinogenesis (2013) 0.95
Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment. Genome Med (2011) 0.94
A note on phasing long genomic regions using local haplotype predictions. J Bioinform Comput Biol (2006) 0.93
Joint analysis of multiple metagenomic samples. PLoS Comput Biol (2012) 0.93
Haplotype reconstruction using perfect phylogeny and sequence data. BMC Bioinformatics (2012) 0.93
Algorithms for efficient near-perfect phylogenetic tree reconstruction in theory and practice. IEEE/ACM Trans Comput Biol Bioinform (2007) 0.92
Association of estrogen receptor alpha polymorphisms with breast cancer risk in older Caucasian women. Int J Cancer (2005) 0.92
Pedigree reconstruction using identity by descent. J Comput Biol (2011) 0.91
Population differences in breast cancer severity. Pharmacogenomics (2008) 0.91
Presymptomatic risk assessment for chronic non-communicable diseases. PLoS One (2010) 0.90