Published in Arch Intern Med on October 11, 2010
The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab (2010) 13.29
Dietary supplements and mortality rate in older women: the Iowa Women's Health Study. Arch Intern Med (2011) 6.69
Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 5.25
Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 4.40
Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals. Am J Clin Nutr (2014) 2.81
Influence of nitrous oxide anesthesia, B-vitamins, and MTHFR gene polymorphisms on perioperative cardiac events: the vitamins in nitrous oxide (VINO) randomized trial. Anesthesiology (2013) 2.39
Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50,000 individuals. Lancet (2013) 2.37
Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial. Lancet Neurol (2012) 2.19
Paradoxical absence of a prothrombotic phenotype in a mouse model of severe hyperhomocysteinemia. Blood (2011) 2.02
Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial. BMJ (2010) 1.89
Sex/gender differences in cardiovascular disease prevention: what a difference a decade makes. Circulation (2011) 1.88
Effects of oxidative stress on fatty acid- and one-carbon-metabolism in psychiatric and cardiovascular disease comorbidity. Acta Psychiatr Scand (2014) 1.65
A prospective controlled study of kidney donors: baseline and 6-month follow-up. Am J Kidney Dis (2013) 1.55
A prospective controlled study of living kidney donors: three-year follow-up. Am J Kidney Dis (2015) 1.48
Folic acid food fortification-its history, effect, concerns, and future directions. Nutrients (2011) 1.46
Folate and vitamin B-12 biomarkers in NHANES: history of their measurement and use. Am J Clin Nutr (2011) 1.33
Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med (2012) 1.27
Maternal nutritional status, C(1) metabolism and offspring DNA methylation: a review of current evidence in human subjects. Proc Nutr Soc (2011) 1.25
Cancer risk with folic acid supplements: a systematic review and meta-analysis. BMJ Open (2012) 1.20
Limitations of observational evidence: implications for evidence-based dietary recommendations. Adv Nutr (2014) 1.19
Homocysteine imbalance: a pathological metabolic marker. Adv Nutr (2012) 1.14
Vitamin and mineral supplements: do we really need them? Int J Prev Med (2012) 1.14
Dietary micronutrient intakes are associated with markers of inflammation but not with markers of subclinical atherosclerosis. J Nutr (2011) 1.10
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr (2013) 1.08
Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease. EMBO Mol Med (2014) 1.04
Epigenetic mechanisms in anti-cancer actions of bioactive food components--the implications in cancer prevention. Br J Pharmacol (2012) 1.03
Homocysteine and vascular disease: review of published results of the homocysteine-lowering trials. J Inherit Metab Dis (2010) 0.98
Biomarkers of Nutrition for Development-Folate Review. J Nutr (2015) 0.98
Neural tube defects, folic acid and methylation. Int J Environ Res Public Health (2013) 0.95
Folate and Alzheimer: when time matters. J Neural Transm (Vienna) (2012) 0.93
Folic acid supplementation promotes mammary tumor progression in a rat model. PLoS One (2014) 0.92
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease. Atherosclerosis (2014) 0.90
Effect of folic acid supplementation in pregnancy on preeclampsia: the folic acid clinical trial study. J Pregnancy (2013) 0.89
Why do young people with chronic kidney disease die early? World J Nephrol (2014) 0.87
Revised D-A-CH intake recommendations for folate: how much is needed? Eur J Clin Nutr (2014) 0.85
Nutrient intake values for folate during pregnancy and lactation vary widely around the world. Nutrients (2013) 0.85
Plasma homocysteine level and hepatic sulfur amino acid metabolism in mice fed a high-fat diet. Eur J Nutr (2012) 0.84
Stroke and nutrition: a review of studies. Int J Prev Med (2013) 0.83
Folate intake and incidence of hypertension among American young adults: a 20-y follow-up study. Am J Clin Nutr (2012) 0.83
Multivitamin-mineral use is associated with reduced risk of cardiovascular disease mortality among women in the United States. J Nutr (2015) 0.83
Press releases issued by supplements industry organisations and non-industry organisations in response to publication of clinical research findings: a case-control study. PLoS One (2014) 0.82
Preventing aggressive prostate cancer with proven cardiovascular disease preventive methods. Asian J Androl (2015) 0.81
Homocysteine and familial longevity: the Leiden Longevity Study. PLoS One (2011) 0.81
Water-soluble vitamins in people with low glomerular filtration rate or on dialysis: a review. Semin Dial (2013) 0.80
Fortification of corn masa flour with folic acid in the United States. Am J Public Health (2011) 0.80
Dietary supplements and risk of cause-specific death, cardiovascular disease, and cancer: a protocol for a systematic review and network meta-analysis of primary prevention trials. Syst Rev (2015) 0.80
The Molecular and Cellular Effect of Homocysteine Metabolism Imbalance on Human Health. Int J Mol Sci (2016) 0.80
Derivation and validation of homocysteine score in u.s. Men and women. J Nutr (2014) 0.79
Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios. J Transl Med (2013) 0.79
Global epidemiology of obesity, vegetarian dietary patterns, and noncommunicable disease in Asian Indians. Am J Clin Nutr (2014) 0.79
Multi-Level Models of Internalizing Disorders and Translational Developmental Science: Seeking Etiological Insights that can Inform Early Intervention Strategies. J Abnorm Child Psychol (2015) 0.79
Choline metabolites: gene by diet interactions. Curr Opin Lipidol (2016) 0.78
Notorious oxide. Anesthesiology (2012) 0.78
Polyunsaturated fatty acids in serum and homocysteine concentrations in Japanese men and women: a cross-sectional study. Nutr Metab (Lond) (2013) 0.78
Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials. J Am Heart Assoc (2016) 0.78
The vital amines: too much of a good thing?: comment on "Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality". Arch Intern Med (2010) 0.78
Heart healthy equals prostate healthy and statins, aspirin, and/or metformin (S.A.M.) are the ideal recommendations for prostate cancer prevention. Asian J Androl (2015) 0.78
Folate consumption and cancer risk: a confirmation and some reassurance, but we're not out of the woods quite yet. Am J Clin Nutr (2011) 0.78
Homocysteine levels and treatment effect in the PROspective Study of Pravastatin in the Elderly at Risk. J Am Geriatr Soc (2014) 0.78
Response of serum and red blood cell folate concentrations to folic acid supplementation depends on methylenetetrahydrofolate reductase C677T genotype: results from a crossover trial. Mol Nutr Food Res (2013) 0.78
Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRα/c-SRC/ERK1/2/NFκB/TP53 pathway: in vitro and in vivo studies. Sci Rep (2015) 0.77
Net improvement of correct answers to therapy questions after pubmed searches: pre/post comparison. J Med Internet Res (2013) 0.77
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats. Nutrients (2015) 0.77
The association between circulating total folate and folate vitamers with overall survival after postmenopausal breast cancer diagnosis. Nutr Cancer (2015) 0.76
Predictors of residual cardiovascular risk in patients on statin therapy for primary prevention. Cardiology (2011) 0.76
Herbal, vitamin, and mineral supplement use in patients enrolled in a cardiac rehabilitation program. J Cardiopulm Rehabil Prev (2012) 0.76
Interactions between plasma homocysteine and arterial stiffness in chronic kidney disease in community-dwelling individuals: The Maine-Syracuse Study. J Hum Hypertens (2015) 0.76
Folic acid in pregnancy and mortality from cancer and cardiovascular disease: further follow-up of the Aberdeen folic acid supplementation trial. J Epidemiol Community Health (2015) 0.76
Update on the NCEP ATP-III emerging cardiometabolic risk factors. BMC Med (2014) 0.76
No effect of folic acid supplementation on cardiovascular events, cancer or mortality after 5 years in people at increased cardiovascular risk, although homocysteine levels are reduced. Evid Based Med (2011) 0.76
Association between B vitamins supplementation and risk of cardiovascular outcomes: a cumulative meta-analysis of randomized controlled trials. PLoS One (2014) 0.76
Daily multivitamins to reduce mortality, cardiovascular disease, and cancer. Can Fam Physician (2013) 0.76
Childhood Leukemia and Primary Prevention. Curr Probl Pediatr Adolesc Health Care (2016) 0.76
New insights into the metabolic and nutritional determinants of severe combined immunodeficiency. Rare Dis (2015) 0.76
The end of evidence-based medicine? Inflammopharmacology (2012) 0.76
Decreased incidence of myelomeningocele at birth: effect of folic acid recommendations or prenatal diagnostics? Childs Nerv Syst (2011) 0.75
Determinants of neural tube defect (NTD)-protective circulating concentrations of folate in women of child-bearing age in the US post-folic acid fortification era. Nutr Res Pract (2013) 0.75
Lowering homocysteine of limited benefit? Nutr Rev (2010) 0.75
Dietary Supplements and Risk of Cause-Specific Death, Cardiovascular Disease, and Cancer: A Systematic Review and Meta-Analysis of Primary Prevention Trials. Adv Nutr (2017) 0.75
Prevention: B vitamins and CVD--failure to find a simple solution. Nat Rev Cardiol (2010) 0.75
Approaches for the identification of genetic modifiers of nutrient dependent phenotypes: examples from folate. Front Nutr (2014) 0.75
Association of MTHFR genetic polymorphisms with venous thromboembolism in Uyghur population in Xinjiang, China. Int J Clin Exp Med (2015) 0.75
The risk of atrial fibrillation in patients with gout: a nationwide population-based study. Sci Rep (2016) 0.75
The Pediatric Methionine Requirement Should Incorporate Remethylation Potential and Transmethylation Demands. Adv Nutr (2016) 0.75
Trends in clinical laboratory homocysteine testing from 1997 to 2010: the impact of evidence on clinical practice at a single institution. Clin Chem Lab Med (2013) 0.75
Severe hyperhomocysteinemia due to cystathionine β-synthase deficiency, and Factor V Leiden mutation in a patient with recurrent venous thrombosis. Thromb J (2014) 0.75
Is there a causal role for homocysteine concentration in blood pressure? A Mendelian randomization study. Am J Clin Nutr (2015) 0.75
Effect of vitamin B supplementation on cancer incidence, death due to cancer, and total mortality: A PRISMA-compliant cumulative meta-analysis of randomized controlled trials. Medicine (Baltimore) (2016) 0.75
Time to Think About Nutrient Needs in Chronic Disease. JAMA Intern Med (2016) 0.75
Association between plasma homocysteine and myocardial SPECT abnormalities in patients referred for suspected myocardial ischaemia. Cardiovasc J Afr (2012) 0.75
Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats. Nutrients (2016) 0.75
A review of the effect of diet on cardiovascular calcification. Int J Mol Sci (2015) 0.75
The Role of Emerging Risk Factors in Cardiovascular Outcomes. Curr Atheroscler Rep (2017) 0.75
Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia. PLoS One (2017) 0.75
Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation. Vasc Health Risk Manag (2014) 0.75
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 56.72
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 41.47
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet (2002) 40.37
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95
Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet (2009) 26.09
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ (2004) 24.88
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med (2005) 17.32
Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet (2007) 15.27
Risk of ischemic heart disease in women after radiotherapy for breast cancer. N Engl J Med (2013) 13.92
MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet (2003) 13.69
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet (2009) 13.64
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2008) 13.35
The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab (2010) 13.29
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 12.44
Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09
Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 12.09
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet (2009) 11.81
Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA (2004) 11.69
Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2011) 11.02
Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J (2006) 10.77
Major lipids, apolipoproteins, and risk of vascular disease. JAMA (2009) 10.58
Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA (2007) 10.50
A nationally representative case-control study of smoking and death in India. N Engl J Med (2008) 10.21
Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA (2003) 10.05
Effects of extended-release niacin with laropiprant in high-risk patients. N Engl J Med (2014) 9.25
A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med (2003) 9.24
Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet (2011) 9.07
Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 9.03
Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med (2006) 8.73
Genetic variants associated with Lp(a) lipoprotein level and coronary disease. N Engl J Med (2009) 8.73
Adiposity as compared with physical activity in predicting mortality among women. N Engl J Med (2004) 8.63
Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 8.32
Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascular Medicine. J Am Soc Echocardiogr (2008) 7.91
Adult and child malaria mortality in India: a nationally representative mortality survey. Lancet (2010) 7.89
21st-century hazards of smoking and benefits of cessation in the United States. N Engl J Med (2013) 7.77
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care (2003) 7.40
C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men. Circulation (2008) 7.33
Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med (2002) 7.32
Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med (2013) 7.29
The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UK. Lancet (2012) 7.28
Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA (2010) 7.12
Vitamin A supplementation every 6 months with retinol in 1 million pre-school children in north India: DEVTA, a cluster-randomised trial. Lancet (2013) 7.04
Atrial fibrillation in patients with cryptogenic stroke. N Engl J Med (2014) 6.73
Calcium/vitamin D supplementation and cardiovascular events. Circulation (2007) 6.63
Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation (2003) 6.62
Smoking and mortality from tuberculosis and other diseases in India: retrospective study of 43000 adult male deaths and 35000 controls. Lancet (2003) 6.58
Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 6.51
Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen. J Clin Oncol (2009) 6.51
Body-mass index and mortality among adults with incident type 2 diabetes. N Engl J Med (2014) 6.51
Tobacco use in 3 billion individuals from 16 countries: an analysis of nationally representative cross-sectional household surveys. Lancet (2012) 6.49
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation (2007) 6.34
Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med (2007) 6.29
Results of multivariable logistic regression, propensity matching, propensity adjustment, and propensity-based weighting under conditions of nonuniform effect. Am J Epidemiol (2005) 6.20
Migraine and risk of cardiovascular disease in women. JAMA (2006) 6.16
Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med (2009) 6.16
UK health performance: findings of the Global Burden of Disease Study 2010. Lancet (2013) 6.11
2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the adult. Can J Cardiol (2013) 5.97
Unravelling the fetal origins hypothesis: is there really an inverse association between birthweight and subsequent blood pressure? Lancet (2002) 5.91
Inflammatory markers and the risk of coronary heart disease in men and women. N Engl J Med (2004) 5.86
C-reactive protein and the risk of developing hypertension. JAMA (2003) 5.75
Low-fat dietary pattern and weight change over 7 years: the Women's Health Initiative Dietary Modification Trial. JAMA (2006) 5.75
Social inequalities in male mortality, and in male mortality from smoking: indirect estimation from national death rates in England and Wales, Poland, and North America. Lancet (2006) 5.70
Coffee consumption and risk for type 2 diabetes mellitus. Ann Intern Med (2004) 5.67
2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult - 2009 recommendations. Can J Cardiol (2009) 5.65
Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA (2009) 5.63
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA (2005) 5.60