Published in J Natl Cancer Inst on April 15, 2011
Statin Therapy Versus Placebo Prior to Prostatectomy | NCT00572468
Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors. PLoS One (2012) 1.89
Statin use and risk of prostate cancer: a meta-analysis of observational studies. PLoS One (2012) 1.74
Cholesterol and prostate cancer. Curr Opin Pharmacol (2012) 1.28
Statin use and fatal prostate cancer: a matched case-control study. Cancer (2011) 1.28
Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1. Cancer Res (2012) 1.10
Shared common variants in prostate cancer and blood lipids. Int J Epidemiol (2014) 1.06
Statin use in relation to prostate cancer outcomes in a population-based patient cohort study. Prostate (2013) 1.06
Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis. Proc Natl Acad Sci U S A (2012) 0.99
Obesity and cancer: mechanistic insights from transdisciplinary studies. Endocr Relat Cancer (2015) 0.96
Statin use as a moderator of metformin effect on risk for prostate cancer among type 2 diabetic patients. Diabetes Care (2012) 0.94
Automated identification of surveillance colonoscopy in inflammatory bowel disease using natural language processing. Dig Dis Sci (2012) 0.92
Serum lipid profile and risk of prostate cancer recurrence: Results from the SEARCH database. Cancer Epidemiol Biomarkers Prev (2014) 0.92
Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites. PLoS One (2011) 0.89
Statin drug use is not associated with prostate cancer risk in men who are regularly screened. J Urol (2014) 0.83
Validation of Case Finding Algorithms for Hepatocellular Cancer From Administrative Data and Electronic Health Records Using Natural Language Processing. Med Care (2016) 0.81
Statins and Finasteride Use Differentially Modify the Impact of Metformin on Prostate Cancer Incidence in Men with Type 2 Diabetes. Ann Transl Med Epidemiol (2015) 0.80
Oral simvastatin administration delays castration-resistant progression and reduces intratumoral steroidogenesis of LNCaP prostate cancer xenografts. Prostate Cancer Prostatic Dis (2015) 0.78
LDL-lowering therapy and the risk of prostate cancer: a meta-analysis of 6 randomized controlled trials and 36 observational studies. Sci Rep (2016) 0.77
Cholesterol and prostate cancer risk: a long-term prospective cohort study. BMC Cancer (2016) 0.77
Racial Differences in the Association Between Preoperative Serum Cholesterol and Prostate Cancer Recurrence: Results from the SEARCH Database. Cancer Epidemiol Biomarkers Prev (2016) 0.77
Statin use and risk of prostate cancer in the prospective Osteoporotic Fractures in Men (MrOS) Study. Cancer Epidemiol Biomarkers Prev (2012) 0.76
Does metabolic syndrome or its components associate with prostate cancer when diagnosed on biopsy? Ther Adv Med Oncol (2015) 0.76
Cholesterol Metabolism and Prostate Cancer Lethality. Cancer Res (2016) 0.75
Statin Use in Prostate Cancer: An Update. Nutr Metab Insights (2016) 0.75
Current and Emerging Uses of Statins in Clinical Therapeutics: A Review. Lipid Insights (2016) 0.75
Low-density lipoprotein receptors play an important role in the inhibition of prostate cancer cell proliferation by statins. Prostate Int (2016) 0.75
Prostate cancer chemoprevention in men of African descent: current state of the art and opportunities for future research. Cancer Causes Control (2013) 0.75
Effects of statin use on the response duration to androgen deprivation therapy in metastatic prostate cancer. Korean J Urol (2015) 0.75
A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med (2005) 17.32
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2008) 13.35
Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 12.09
Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2011) 11.02
Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 9.03
Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 8.32
C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men. Circulation (2008) 7.33
Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Intern Med (2010) 6.48
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation (2007) 6.34
Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med (2007) 6.29
Results of multivariable logistic regression, propensity matching, propensity adjustment, and propensity-based weighting under conditions of nonuniform effect. Am J Epidemiol (2005) 6.20
Migraine and risk of cardiovascular disease in women. JAMA (2006) 6.16
Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med (2009) 6.16
C-reactive protein and the risk of developing hypertension. JAMA (2003) 5.75
Laboratory-based versus non-laboratory-based method for assessment of cardiovascular disease risk: the NHANES I Follow-up Study cohort. Lancet (2008) 5.49
Measures of obesity and cardiovascular risk among men and women. J Am Coll Cardiol (2008) 5.28
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89
Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 4.40
A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial. Ann Intern Med (2012) 4.10
New models for large prospective studies: is there a better way? Am J Epidemiol (2012) 3.85
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis. Lancet Oncol (2008) 3.62
Comparison of self-report, hospital discharge codes, and adjudication of cardiovascular events in the Women's Health Initiative. Am J Epidemiol (2004) 3.53
The association between statins and cancer incidence in a veterans population. J Natl Cancer Inst (2008) 3.40
A randomized factorial trial of vitamins C and E and beta carotene in the secondary prevention of cardiovascular events in women: results from the Women's Antioxidant Cardiovascular Study. Arch Intern Med (2007) 3.37
A prospective study of plasma selenium levels and prostate cancer risk. J Natl Cancer Inst (2004) 3.32
Relationship of physical activity vs body mass index with type 2 diabetes in women. JAMA (2004) 3.31
Overcoming barriers to NLP for clinical text: the role of shared tasks and the need for additional creative solutions. J Am Med Inform Assoc (2011) 3.14
Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer. J Natl Cancer Inst (2002) 3.03
Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT). J Natl Cancer Inst (2005) 2.99
Body mass index and the risk of stroke in men. Arch Intern Med (2002) 2.90
Relation between modifiable lifestyle factors and lifetime risk of heart failure. JAMA (2009) 2.90
A prospective cohort study of cancer incidence following the diagnosis of Parkinson's disease. Cancer Epidemiol Biomarkers Prev (2007) 2.77
Prospective study of body mass index and risk of stroke in apparently healthy women. Circulation (2005) 2.73
Inhibition of clinical benefits of aspirin on first myocardial infarction by nonsteroidal antiinflammatory drugs. Circulation (2003) 2.73
Proton pump inhibitors and risk for recurrent Clostridium difficile infection. Arch Intern Med (2010) 2.71
Exceptional longevity in men: modifiable factors associated with survival and function to age 90 years. Arch Intern Med (2008) 2.67
Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health Study. Am J Clin Nutr (2008) 2.61
Genome-wide association study identifies new prostate cancer susceptibility loci. Hum Mol Genet (2011) 2.51
Migraine and risk of cardiovascular disease in men. Arch Intern Med (2007) 2.49
Migraine, vascular risk, and cardiovascular events in women: prospective cohort study. BMJ (2008) 2.48
Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent. Arch Intern Med (2011) 2.43
A prospective study of body mass index and the risk of developing hypertension in men. Am J Hypertens (2007) 2.43
Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50,000 individuals. Lancet (2013) 2.37
Practitioner-level determinants of inappropriate prostate-specific antigen screening. Arch Intern Med (2007) 2.34
Effect of combined folic acid, vitamin B6, and vitamin B12 on cancer risk in women: a randomized trial. JAMA (2008) 2.32
Association between body mass index and CKD in apparently healthy men. Am J Kidney Dis (2005) 2.30
Dietary omega-3 fatty acids and fish consumption and risk of type 2 diabetes. Am J Clin Nutr (2010) 2.25
A prospective study of plasma C-peptide and colorectal cancer risk in men. J Natl Cancer Inst (2004) 2.22
A prospective study of plasma vitamin D metabolites, vitamin D receptor polymorphisms, and prostate cancer. PLoS Med (2007) 2.20
A randomized trial of beta carotene supplementation and cognitive function in men: the Physicians' Health Study II. Arch Intern Med (2007) 2.20
Body mass index and vigorous physical activity and the risk of heart failure among men. Circulation (2008) 2.19
Fish consumption, omega-3 fatty acids and risk of heart failure: a meta-analysis. Clin Nutr (2012) 2.14
Egg consumption and risk of type 2 diabetes in men and women. Diabetes Care (2008) 2.14
Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trial. J Natl Cancer Inst (2008) 2.07
Healthy lifestyle and the risk of stroke in women. Arch Intern Med (2006) 2.02
Incidence of cardiovascular disease and cancer in advanced age: prospective cohort study. BMJ (2008) 2.01
Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer. Cancer Res (2005) 1.98
Vitamin supplement use in a low-risk population of US male physicians and subsequent cardiovascular mortality. Arch Intern Med (2002) 1.97
Alcohol consumption and the risk of hypertension in women and men. Hypertension (2008) 1.96
Genome-wide association study of glioma and meta-analysis. Hum Genet (2012) 1.96
An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation. BMC Bioinformatics (2004) 1.95
Geographic patterns in overall and specific cardiovascular disease incidence in apparently healthy men in the United States. Stroke (2007) 1.91
A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen. Clin Trials (2011) 1.91
Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan). Arch Intern Med (2010) 1.88
Nut consumption and risk of hypertension in US male physicians. Clin Nutr (2008) 1.88
Cholesterol and the risk of renal dysfunction in apparently healthy men. J Am Soc Nephrol (2003) 1.87
Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility. Proc Natl Acad Sci U S A (2009) 1.81
Relation of vigorous exercise to risk of atrial fibrillation. Am J Cardiol (2009) 1.79
Flavonoid intake and the risk of cardiovascular disease in women. Am J Clin Nutr (2003) 1.79
Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study. Arch Ophthalmol (2008) 1.74
Nut consumption and decreased risk of sudden cardiac death in the Physicians' Health Study. Arch Intern Med (2002) 1.73
Alcohol consumption and risk of heart failure in the Physicians' Health Study I. Circulation (2006) 1.68
Genome-wide association study of survival in patients with pancreatic adenocarcinoma. Gut (2012) 1.66
Randomized clinical trial of quick-release bromocriptine among patients with type 2 diabetes on overall safety and cardiovascular outcomes. Diabetes Care (2010) 1.65
Smoking and risk of hemorrhagic stroke in women. Stroke (2003) 1.63
Age-related cataract in a randomized trial of vitamins E and C in men. Arch Ophthalmol (2010) 1.60
Statin use and fracture risk: study of a US veterans population. Arch Intern Med (2005) 1.58
Chronic disease in men with newly diagnosed cancer: a nested case-control study. Am J Epidemiol (2010) 1.58
Dyslipidemia and the risk of incident hypertension in men. Hypertension (2005) 1.54
Comparison of interleukin-6 and C-reactive protein for the risk of developing hypertension in women. Hypertension (2006) 1.53
Change in use of gadolinium-enhanced magnetic resonance studies in kidney disease patients after US Food and Drug Administration warnings: a cross-sectional study of Veterans Affairs Health Care System data from 2005-2008. Am J Kidney Dis (2010) 1.52
Incidence and remaining lifetime risk of Parkinson disease in advanced age. Neurology (2009) 1.48
A meta-analysis of omega-3 fatty acids and incidence of atrial fibrillation. J Am Coll Nutr (2012) 1.47
Effect of treating erectile dysfunction on management of systolic hypertension. Am J Cardiol (2007) 1.46
Alcohol consumption and mortality in men with preexisting cerebrovascular disease. Arch Intern Med (2003) 1.45
Plasma carotenoids and tocopherols and risk of myocardial infarction in a low-risk population of US male physicians. Circulation (2003) 1.44
Type 2 diabetes mellitus and cognitive decline in two large cohorts of community-dwelling older adults. J Am Geriatr Soc (2008) 1.44
Thrombocytopenia and bleeding in veterans with non-hepatitis C-related chronic liver disease. Dig Dis Sci (2012) 1.42
Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3. PLoS One (2011) 1.41
Development of a risk score for colorectal cancer in men. Am J Med (2007) 1.39
Phase III trial of selenium to prevent prostate cancer in men with high-grade prostatic intraepithelial neoplasia: SWOG S9917. Cancer Prev Res (Phila) (2011) 1.38
Analgesic use and change in kidney function in apparently healthy men. Am J Kidney Dis (2003) 1.37
Prescription opioid analgesics increase the risk of depression. J Gen Intern Med (2013) 1.37