Published in Hippocampus on July 20, 2012
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry (2014) 1.09
Neurotrophic natural products: chemistry and biology. Angew Chem Int Ed Engl (2013) 0.96
Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels. PLoS One (2013) 0.89
The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment. Neurotherapeutics (2015) 0.84
St. John's Wort enhances the synaptic activity of the nucleus of the solitary tract. Nutrition (2014) 0.79
Modeling autism spectrum disorders with human neurons. Brain Res (2016) 0.78
The mechanisms of action of St. John's wort: an update. Wien Med Wochenschr (2015) 0.78
TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways. Sci Rep (2016) 0.77
CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation. PLoS One (2016) 0.77
Shuganjieyu capsule increases neurotrophic factor expression in a rat model of depression. Neural Regen Res (2014) 0.76
Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment. J Neurosci (2016) 0.76
Artemisia santolinifolia enhances glutamatergic neurotransmission in the nucleus of the solitary tract. Neurosci Lett (2014) 0.75
Hypericum caprifoliatum and Hypericum connatum affect human trophoblast-like cells differentiation and Ca(2+) influx. Asian Pac J Trop Biomed (2014) 0.75
Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion. Front Physiol (2017) 0.75
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (2003) 16.14
A simple method for organotypic cultures of nervous tissue. J Neurosci Methods (1991) 14.18
Global burden of depressive disorders in the year 2000. Br J Psychiatry (2004) 9.25
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci (2000) 9.12
TRP channels. Annu Rev Biochem (2007) 8.09
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature (1999) 6.85
Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation. J Neurosci (1992) 5.37
Structure-stability-function relationships of dendritic spines. Trends Neurosci (2003) 4.80
Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. J Neurosci (1999) 4.59
Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology (2007) 4.38
Anatomical and physiological plasticity of dendritic spines. Annu Rev Neurosci (2007) 3.75
St John's wort for major depression. Cochrane Database Syst Rev (2008) 3.27
Organotypic monolayer cultures of nervous tissue. J Neurosci Methods (1981) 3.19
Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry (2003) 2.82
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature (2005) 2.78
BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends Neurosci (2004) 2.76
Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology (2009) 2.63
BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. J Neurosci (2001) 2.51
TRPC channels promote cerebellar granule neuron survival. Nat Neurosci (2007) 2.47
Role of neurotrophic factors in depression. Curr Opin Pharmacol (2006) 2.39
Formation of novel TRPC channels by complex subunit interactions in embryonic brain. J Biol Chem (2003) 2.29
Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. J Neurosci (2002) 2.21
Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. Neuron (1999) 2.15
A longitudinal study of hippocampal volume, cortisol levels, and cognition in older depressed subjects. Am J Psychiatry (2004) 2.12
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons. Learn Mem (2004) 1.99
Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Med (2004) 1.94
Neuronal transfection in brain slices using particle-mediated gene transfer. Neuron (1994) 1.87
TRP ion channels in the nervous system. Curr Opin Neurobiol (2004) 1.78
Pathophysiology of depression: the concept of synaptic plasticity. Eur Psychiatry (2002) 1.75
The small pyramidal neuron of the rat cerebral cortex. The synapses upon dendritic spines. Z Zellforsch Mikrosk Anat (1969) 1.69
Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones. J Physiol (2003) 1.67
Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations. Neurobiol Dis (2009) 1.66
Antidepressants and neuroplasticity. Bipolar Disord (2002) 1.66
TRPC3 channels are necessary for brain-derived neurotrophic factor to activate a nonselective cationic current and to induce dendritic spine formation. J Neurosci (2007) 1.56
An image analysis algorithm for dendritic spines. Neural Comput (2002) 1.48
St John's wort for depression: meta-analysis of randomised controlled trials. Br J Psychiatry (2005) 1.40
Hyperforin--a key constituent of St. John's wort specifically activates TRPC6 channels. FASEB J (2007) 1.31
Ageing abolishes the effects of fluoxetine on neurogenesis. Mol Psychiatry (2009) 1.28
Amygdala and hippocampal volumes in familial early onset major depressive disorder. Biol Psychiatry (2007) 1.25
Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus. Eur J Neurosci (2005) 1.24
Critical role of TRPC6 channels in the formation of excitatory synapses. Nat Neurosci (2008) 1.22
Hyperforin represents the neurotransmitter reuptake inhibiting constituent of hypericum extract. Pharmacopsychiatry (1998) 1.22
Neural connections between the lateral geniculate nucleus and visual cortex in vitro. Science (1989) 1.18
Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression. Biol Psychiatry (2008) 1.16
Dendritic spines, synaptic plasticity and neuronal survival: activity shapes dendritic spines to enhance neuronal viability. Eur J Neurosci (2010) 1.12
BDNF induces calcium elevations associated with IBDNF, a nonselective cationic current mediated by TRPC channels. J Neurophysiol (2007) 1.08
TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway. J Cell Sci (2008) 1.07
Activity-dependent release of endogenous BDNF from mossy fibers evokes a TRPC3 current and Ca2+ elevations in CA3 pyramidal neurons. J Neurophysiol (2010) 1.06
Simple 2,4-diacylphloroglucinols as classic transient receptor potential-6 activators--identification of a novel pharmacophore. Mol Pharmacol (2009) 1.05
Current St John's wort research from mode of action to clinical efficacy. Pharmacol Res (2003) 1.04
Age-dependent decline in hippocampal neurogenesis is not altered by chronic treatment with fluoxetine. Brain Res (2008) 1.02
Chronic fluoxetine treatment induces structural plasticity and selective changes in glutamate receptor subunits in the rat cerebral cortex. Neuroscience (2010) 0.98
The spine apparatus, synaptopodin, and dendritic spine plasticity. Neuroscientist (2010) 0.95
Optical imaging of cytosolic calcium, electrophysiology, and ultrastructure in pyramidal neurons of organotypic slice cultures from rat hippocampus. Neuroimage (1993) 0.95
Hyperforin, a major antidepressant constituent of St. John's Wort, inhibits serotonin uptake by elevating free intracellular Na+1. J Pharmacol Exp Ther (1999) 0.91
Synaptic adaptations of CA1 pyramidal neurons induced by a highly effective combinational antidepressant therapy. Biol Psychiatry (2010) 0.89
Changes in rat hippocampal CA1 synapses following imipramine treatment. Hippocampus (2008) 0.88
Hyperforin activates nonselective cation channels (NSCCs). Br J Pharmacol (2005) 0.84
Inhibition of synaptosomal uptake of 3H-L-glutamate and 3H-GABA by hyperforin, a major constituent of St. John's Wort: the role of amiloride sensitive sodium conductive pathways. Neuropsychopharmacology (2000) 0.82
Diacylglycerol analogues activate second messenger-operated calcium channels exhibiting TRPC-like properties in cortical neurons. J Neurochem (2009) 0.82
Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Genome-wide analysis of estrogen receptor binding sites. Nat Genet (2006) 18.63
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell (2005) 14.32
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell (2008) 14.18
Model-based analysis of tiling-arrays for ChIP-chip. Proc Natl Acad Sci U S A (2006) 13.68
Genome-wide association studies of 14 agronomic traits in rice landraces. Nat Genet (2010) 8.75
The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci U S A (2005) 8.60
Model-based analysis of two-color arrays (MA2C). Genome Biol (2007) 7.28
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell (2009) 7.09
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol (2010) 7.00
PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res (2008) 6.73
iPS cells produce viable mice through tetraploid complementation. Nature (2009) 6.51
Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. Lancet (2013) 6.10
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Mol Cell (2007) 5.99
BSMAP: whole genome bisulfite sequence MAPping program. BMC Bioinformatics (2009) 5.67
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell (2002) 5.20
Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med (2003) 4.98
Cardiovascular risk and events in 17 low-, middle-, and high-income countries. N Engl J Med (2014) 4.88
Association of urinary sodium and potassium excretion with blood pressure. N Engl J Med (2014) 4.86
Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet (2011) 4.85
A G protein-coupled receptor is a plasma membrane receptor for the plant hormone abscisic acid. Science (2007) 4.61
RSeQC: quality control of RNA-seq experiments. Bioinformatics (2012) 4.31
Productivity is a poor predictor of plant species richness. Science (2011) 4.21
A novel influenza A (H1N1) vaccine in various age groups. N Engl J Med (2009) 4.20
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Res (2008) 4.08
A broadly implementable research course in phage discovery and genomics for first-year undergraduate students. MBio (2014) 3.93
TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res (2009) 3.79
Receptor-like cytoplasmic kinases integrate signaling from multiple plant immune receptors and are targeted by a Pseudomonas syringae effector. Cell Host Microbe (2010) 3.73
Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nat Biotechnol (2013) 3.65
Meta-analysis of traditional Chinese patent medicine for ischemic stroke. Stroke (2007) 3.46
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat Genet (2009) 3.46
The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients. J Hypertens (2005) 3.27
CEAS: cis-regulatory element annotation system. Nucleic Acids Res (2006) 3.15
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
Analysis of the human endogenous coregulator complexome. Cell (2011) 2.97
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature (2012) 2.96
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc Natl Acad Sci U S A (2009) 2.95
CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model. Nucleic Acids Res (2013) 2.88
Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization. Nature (2008) 2.88
Right ventricular function in adults with repaired tetralogy of Fallot assessed with cardiovascular magnetic resonance imaging: detrimental role of right ventricular outflow aneurysms or akinesia and adverse right-to-left ventricular interaction. J Am Coll Cardiol (2002) 2.87
Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates. Nat Med (2006) 2.83
Function annotation of the rice transcriptome at single-nucleotide resolution by RNA-seq. Genome Res (2010) 2.73
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell (2012) 2.69
A C. elegans model of nicotine-dependent behavior: regulation by TRP-family channels. Cell (2006) 2.68
Genome-wide genetic changes during modern breeding of maize. Nat Genet (2012) 2.60
A complete sequence of the T. tengcongensis genome. Genome Res (2002) 2.60
A new Mycobacterium species causing diffuse lepromatous leprosy. Am J Clin Pathol (2008) 2.59
Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J Biol Chem (2010) 2.59
Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell (2003) 2.54
DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression. Genome Res (2008) 2.48
Mutations in U4atac snRNA, a component of the minor spliceosome, in the developmental disorder MOPD I. Science (2011) 2.47
A drinking water crisis in Lake Taihu, China: linkage to climatic variability and lake management. Environ Manage (2010) 2.45
Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway. Diabetes (2002) 2.44
Early use of noninvasive positive pressure ventilation for acute lung injury: a multicenter randomized controlled trial. Crit Care Med (2012) 2.43
GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis. Nucleic Acids Res (2008) 2.35
Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations. Hum Mol Genet (2009) 2.34
Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing. BMC Genomics (2005) 2.34
Hemorrhagic fever caused by a novel Bunyavirus in China: pathogenesis and correlates of fatal outcome. Clin Infect Dis (2011) 2.34
Parallel processing in two transmitter microenvironments at the cone photoreceptor synapse. Neuron (2006) 2.34
Role of hydrogen sulfide in the development of atherosclerotic lesions in apolipoprotein E knockout mice. Arterioscler Thromb Vasc Biol (2008) 2.29
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Mol Cell (2011) 2.27
ElliPro: a new structure-based tool for the prediction of antibody epitopes. BMC Bioinformatics (2008) 2.26
A phase II trial of Xeloda and oxaliplatin (XELOX) neo-adjuvant chemotherapy followed by surgery for advanced gastric cancer patients with para-aortic lymph node metastasis. Cancer Chemother Pharmacol (2014) 2.26
Derepression of ethylene-stabilized transcription factors (EIN3/EIL1) mediates jasmonate and ethylene signaling synergy in Arabidopsis. Proc Natl Acad Sci U S A (2011) 2.25
Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation. Proc Natl Acad Sci U S A (2003) 2.25
The Drosophila melanogaster transcriptome by paired-end RNA sequencing. Genome Res (2010) 2.25
Identification of drought-induced microRNAs in rice. Biochem Biophys Res Commun (2007) 2.24
The ecology, genetic diversity, and phylogeny of Huaiyangshan virus in China. J Virol (2011) 2.23
Oxysterols direct immune cell migration via EBI2. Nature (2011) 2.19
Ventricular fibrosis suggested by cardiovascular magnetic resonance in adults with repaired tetralogy of fallot and its relationship to adverse markers of clinical outcome. Circulation (2006) 2.18
Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients. JACC Cardiovasc Imaging (2012) 2.17
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A (2006) 2.16
An oligonucleotide microarray for microRNA expression analysis based on labeling RNA with quantum dot and nanogold probe. Nucleic Acids Res (2005) 2.15
Hemorrhagic fever caused by a novel tick-borne Bunyavirus in Huaiyangshan, China. Zhonghua Liu Xing Bing Xue Za Zhi (2011) 2.15
The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism. FEBS J (2005) 2.12
EuPathDB: a portal to eukaryotic pathogen databases. Nucleic Acids Res (2009) 2.11
Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects. Proc Natl Acad Sci U S A (2002) 2.11
Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiation. Cell (2012) 2.02
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons. Learn Mem (2004) 1.99
Symbol "&" suture to control atonic postpartum hemorrhage with placenta previa accreta. Arch Gynecol Obstet (2014) 1.99
High-field (9.4 T) MRI of brain dysmyelination by quantitative mapping of magnetic susceptibility. Neuroimage (2011) 1.98
Middle cerebral artery stenosis: stenting is one of the options: yes. Stroke (2007) 1.97
Job-related burnout and the relationship to quality of life among Chinese medical college staff. Arch Environ Occup Health (2015) 1.97
Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex. Nat Struct Mol Biol (2011) 1.95
Recurrent chimeric RNAs enriched in human prostate cancer identified by deep sequencing. Proc Natl Acad Sci U S A (2011) 1.94
Homo- and heteromeric assembly of TRPV channel subunits. J Cell Sci (2005) 1.93
In vivo evidence for a novel pathway of vitamin D₃ metabolism initiated by P450scc and modified by CYP27B1. FASEB J (2012) 1.92
The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type. Proc Natl Acad Sci U S A (2012) 1.92
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. J Biol Chem (2009) 1.91
Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory response. J Infect Dis (2009) 1.89
Transforming growth factor alpha (TGFalpha)-stimulated secretion of HSP90alpha: using the receptor LRP-1/CD91 to promote human skin cell migration against a TGFbeta-rich environment during wound healing. Mol Cell Biol (2008) 1.88
Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication. Circulation (2005) 1.85
Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc. FEBS J (2008) 1.84
Molecular engineering of DNA: molecular beacons. Angew Chem Int Ed Engl (2009) 1.84
Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice. Gastroenterology (2010) 1.83
Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity. PLoS One (2010) 1.83
The status of glycemic control: A cross-sectional study of outpatients with type 2 diabetes mellitus across primary, secondary, and tertiary hospitals in the Jiangsu province of China. Clin Ther (2010) 1.83
Strontium-doped perovskites rival platinum catalysts for treating NOx in simulated diesel exhaust. Science (2010) 1.82