Published in EMBO Mol Med on July 23, 2012
Induction of entosis by epithelial cadherin expression. Cell Res (2014) 1.13
Rapid reuptake of granzyme B leads to emperitosis: an apoptotic cell-in-cell death of immune killer cells inside tumor cells. Cell Death Dis (2013) 1.01
Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining. Oncotarget (2015) 0.91
Modeling cell-in-cell structure into its biological significance. Cell Death Dis (2013) 0.90
Entosis, a key player in cancer cell competition. Cell Res (2014) 0.88
Fluorescence-Activated Cell Sorting Analysis of Heterotypic Cell-in-Cell Structures. Sci Rep (2015) 0.86
Impaired formation of homotypic cell-in-cell structures in human tumor cells lacking alpha-catenin expression. Sci Rep (2015) 0.83
Autophagy proteins regulate cell engulfment mechanisms that participate in cancer. Semin Cancer Biol (2013) 0.83
Mechanisms and consequences of entosis. Cell Mol Life Sci (2016) 0.83
Cancer cells enter dormancy after cannibalizing mesenchymal stem/stromal cells (MSCs). Proc Natl Acad Sci U S A (2016) 0.83
Prognostic Value of Homotypic Cell Internalization by Nonprofessional Phagocytic Cancer Cells. Biomed Res Int (2015) 0.81
Cell-in-cell phenomenon: A New Paradigm in Life Sciences. Curr Mol Med (2015) 0.79
Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation. Sci Rep (2015) 0.76
Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1. J Cell Physiol (2015) 0.75
Engulfing losers by winners in cancer: do cancer stem cells catch eat-me signals from noncancer stem cells? Future Oncol (2014) 0.75
Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance. Med Res Rev (2016) 0.75
"Stealth dissemination" of macrophage-tumor cell fusions cultured from blood of patients with pancreatic ductal adenocarcinoma. PLoS One (2017) 0.75
Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91
Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
Epithelial-mesenchymal transitions in development and disease. Cell (2009) 39.17
affy--analysis of Affymetrix GeneChip data at the probe level. Bioinformatics (2004) 32.08
Controlling the false discovery rate in behavior genetics research. Behav Brain Res (2001) 21.82
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development (2002) 12.21
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes Dev (2003) 8.27
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A (2006) 5.90
Biological interaction between lymphocytes and other cells. Br J Haematol (1956) 4.70
A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion. Cell (2007) 3.97
Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes. Nat Cell Biol (2011) 3.45
Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells. Cancer Res (2006) 2.77
affylmGUI: a graphical user interface for linear modeling of single channel microarray data. Bioinformatics (2006) 2.74
Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation. Cancer Res (2001) 2.29
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death. Cell Res (2009) 2.07
The cell biology of cell-in-cell structures. Nat Rev Mol Cell Biol (2008) 1.96
Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth. J Biol Chem (1997) 1.67
Clinical significance of "cannibalism" in urinary cytology of bladder cancer. Acta Cytol (1998) 1.59
Expression of a novel factor in human breast cancer cells with metastatic potential. Cancer Res (1999) 1.57
miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells. Int J Cancer (2011) 1.53
Cannibalism: a way to feed on metastatic tumors. Cancer Lett (2007) 1.42
Basics of TGF-beta and pancreatic cancer. Pancreatology (2007) 1.42
p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I. J Biol Chem (2003) 1.35
Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. J Clin Invest (2012) 1.33
Expression of a novel factor, com1, is regulated by 1,25-dihydroxyvitamin D3 in breast cancer cells. Cancer Res (2000) 1.27
TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system. Int J Cancer (2001) 1.24
Cell cannibalism in ductal carcinoma of breast. Cytopathology (2006) 1.24
Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate. Genesis (2007) 1.23
Colitis and colitis-associated cancer are exacerbated in mice deficient for tumor protein 53-induced nuclear protein 1. Mol Cell Biol (2007) 1.22
Tumors of the pancreas with osteoclast-like and pleomorphic giant cells: an immunohistochemical and ploidy study. Arch Pathol Lab Med (1998) 1.16
Nupr1: the Swiss-knife of cancer. J Cell Physiol (2011) 1.15
Cloning and expression of the human p8, a nuclear protein with mitogenic activity. Eur J Biochem (1999) 1.14
p8 is a new target of gemcitabine in pancreatic cancer cells. Clin Cancer Res (2006) 1.11
The human homologue of Dictyostelium discoideum phg1A is expressed by human metastatic melanoma cells. EMBO Rep (2009) 1.06
Cell cannibalism: diagnostic marker of malignancy. Diagn Cytopathol (2003) 1.06
Epithelial-to-mesenchymal transition in pancreatic adenocarcinoma. ScientificWorldJournal (2010) 1.05
The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter. J Cell Sci (2009) 1.01
Expression of p8 in human pancreatic cancer. Clin Cancer Res (2001) 1.01
Transforming growth factor beta-1 enhances Smad transcriptional activity through activation of p8 gene expression. Biochem J (2001) 1.00
Morphological evidence of neutrophil-tumor cell phagocytosis (cannibalism) in human gastric adenocarcinomas. Ultrastruct Pathol (2002) 0.99
Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function. Mol Biol Cell (2010) 0.99
p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth. Mol Cancer (2003) 0.96
Overexpression of p8 is inversely correlated with apoptosis in pancreatic cancer. Clin Cancer Res (2001) 0.96
ArgBP2-dependent signaling regulates pancreatic cell migration, adhesion, and tumorigenicity. Cancer Res (2008) 0.95
Mice with targeted disruption of p8 gene show increased sensitivity to lipopolysaccharide and DNA microarray analysis of livers reveals an aberrant gene expression response. BMC Gastroenterol (2003) 0.94
Xeno-cannibalism as an exacerbation of self-cannibalism: a possible fruitful survival strategy for cancer cells. Curr Pharm Des (2008) 0.93
Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth. Cell Death Differ (2010) 0.92
p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage. J Cell Physiol (2009) 0.92
p8 expression controls pancreatic cancer cell migration, invasion, adhesion, and tumorigenesis. J Cell Physiol (2011) 0.89
Serum-dependent "cannibalism" and autodestruction in cultures of human small cell carcinoma of the lung. Cancer Res (1984) 0.88
Cytologic findings of medulloblastoma in crush smears. Acta Cytol (2001) 0.84
Expression of p8 protein in breast carcinoma; an inverse relationship with apoptosis. Anticancer Res (2005) 0.84
Xeno-cannibalism: a survival "escamotage". Autophagy (2007) 0.84
Emperipolesis of hematopoietic cells in myelocytic leukemia. Electron microscopic and phase contrast microscopic studies. Virchows Arch B Cell Pathol Incl Mol Pathol (1981) 0.84
Stress proteins and pancreatic cancer metastasis. ScientificWorldJournal (2010) 0.82
Tumor cell-tumor cell emperipolesis. Exp Cell Res (1967) 0.77
Fine-needle aspiration biopsy of pleomorphic (giant cell) carcinoma of the pancreas. Cytologic, immunocytochemical, and ultrastructural findings. Am J Clin Pathol (1988) 0.77
Signet ring carcinoma of the pancreas, a rare variant with very high CEA values. Immunohistologic comparison with adenocarcinoma. Dig Dis Sci (1984) 0.76
Autophagy in the pathogenesis of disease. Cell (2008) 34.68
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol (2007) 15.47
The hallmarks of aging. Cell (2013) 14.29
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med (2007) 13.90
The pathophysiology of mitochondrial cell death. Science (2004) 13.87
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J (2007) 11.72
Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med (2006) 10.54
Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol (2005) 10.27
Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol (2010) 9.06
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med (2009) 6.73
Immunological aspects of cancer chemotherapy. Nat Rev Immunol (2008) 6.61
Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol (2006) 6.13
Current development of mTOR inhibitors as anticancer agents. Nat Rev Drug Discov (2006) 5.99
Regulation of autophagy by cytoplasmic p53. Nat Cell Biol (2008) 5.97
Autophagy and aging. Cell (2011) 5.96
Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice. Science (2011) 5.62
Sp1- and Krüppel-like transcription factors. Genome Biol (2003) 5.42
Cytoplasmic functions of the tumour suppressor p53. Nature (2009) 5.23
Induction of autophagy by spermidine promotes longevity. Nat Cell Biol (2009) 5.00
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85
Cell death by mitotic catastrophe: a molecular definition. Oncogene (2004) 4.75
Cell death by necrosis: towards a molecular definition. Trends Biochem Sci (2006) 4.67
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science (2013) 4.60
Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy (2008) 4.42
An immunosurveillance mechanism controls cancer cell ploidy. Science (2012) 4.35
Immunogenic and tolerogenic cell death. Nat Rev Immunol (2009) 4.34
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death. J Exp Med (2005) 4.32
Targeting mitochondria for cancer therapy. Nat Rev Drug Discov (2010) 4.07
Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. Proc Natl Acad Sci U S A (2007) 4.04
The anticancer immune response: indispensable for therapeutic success? J Clin Invest (2008) 4.01
The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death. J Cell Sci (2005) 3.93
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell (2007) 3.82
Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science (2011) 3.74
Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. Immunity (2013) 3.73
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation. J Exp Med (2005) 3.64
The secret ally: immunostimulation by anticancer drugs. Nat Rev Drug Discov (2012) 3.60
Decoding cell death signals in inflammation and immunity. Cell (2010) 3.41
Immune parameters affecting the efficacy of chemotherapeutic regimens. Nat Rev Clin Oncol (2011) 3.41
Mitotic catastrophe: a mechanism for avoiding genomic instability. Nat Rev Mol Cell Biol (2011) 3.40
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells. Immunity (2013) 3.26
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest (2009) 3.23
Does autophagy contribute to cell death? Autophagy (2005) 3.21
A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21
Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties. Cell Cycle (2006) 3.21
AIF deficiency compromises oxidative phosphorylation. EMBO J (2004) 3.19
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L). Autophagy (2007) 3.08
Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med (2011) 3.03
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy. Immunol Rev (2007) 2.96
Stimulation of autophagy by the p53 target gene Sestrin2. Cell Cycle (2009) 2.72
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. EMBO J (2009) 2.72
Platelet formation is the consequence of caspase activation within megakaryocytes. Blood (2002) 2.62
Necroptosis: a specialized pathway of programmed necrosis. Cell (2008) 2.61
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J Exp Med (2003) 2.56
Autophagy regulation by p53. Curr Opin Cell Biol (2010) 2.56
Can autophagy promote longevity? Nat Cell Biol (2010) 2.55
Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome. Gastroenterology (2002) 2.52
Cell death assays for drug discovery. Nat Rev Drug Discov (2011) 2.51
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J Cell Biol (2002) 2.47
The IKK complex contributes to the induction of autophagy. EMBO J (2009) 2.41
Fatty acids trigger mitochondrion-dependent necrosis. Cell Cycle (2010) 2.37
Complex inhibitory effects of nitric oxide on autophagy. Mol Cell (2011) 2.36
An AIF orthologue regulates apoptosis in yeast. J Cell Biol (2004) 2.33
Metabolic targets for cancer therapy. Nat Rev Drug Discov (2013) 2.32
Defining the critical hurdles in cancer immunotherapy. J Transl Med (2011) 2.32
A study of candidate genotypes associated with dyspepsia in a U.S. community. Am J Gastroenterol (2006) 2.30
Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway. Clin Cancer Res (2010) 2.29
Mitochondria: master regulators of danger signalling. Nat Rev Mol Cell Biol (2012) 2.28
miR-181a and miR-630 regulate cisplatin-induced cancer cell death. Cancer Res (2010) 2.24
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome. J Cell Biol (2011) 2.23
Viral control of mitochondrial apoptosis. PLoS Pathog (2008) 2.21
Nonapoptotic role for Apaf-1 in the DNA damage checkpoint. Mol Cell (2007) 2.20
Prognostic and predictive impact of intra- and peritumoral immune infiltrates. Cancer Res (2011) 2.16
Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity. Mol Cell (2012) 2.14
Alternative cell death mechanisms in development and beyond. Genes Dev (2010) 2.14
Type III procollagen is a reliable marker of ARDS-associated lung fibroproliferation. Intensive Care Med (2014) 2.12
Evidence for the existence of an HP1-mediated subcode within the histone code. Nat Cell Biol (2006) 2.11
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene (2003) 2.09
TGF-β: duality of function between tumor prevention and carcinogenesis. J Natl Cancer Inst (2014) 2.08
[Accuracy of intraoperative frozen section diagnosis in non palpable breast lesions: a series of 791 cases]. Bull Cancer (2003) 2.08
Involvement of p38alpha in the mitotic progression of p53(-/-) tetraploid cells. Cell Cycle (2010) 2.08
The Heterochromatin Protein 1 family. Genome Biol (2006) 2.05
Sin3: master scaffold and transcriptional corepressor. Biochim Biophys Acta (2009) 2.05
Decoding cell death signals in liver inflammation. J Hepatol (2013) 2.05
To die or not to die: that is the autophagic question. Curr Mol Med (2008) 2.05
Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J Exp Med (2011) 2.04
Methods for the assessment of mitochondrial membrane permeabilization in apoptosis. Apoptosis (2007) 2.04
Mutant p53 protein localized in the cytoplasm inhibits autophagy. Cell Cycle (2008) 2.03
A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy (2011) 2.02
Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis. Cancer Cell (2005) 2.01
A comprehensive glossary of autophagy-related molecules and processes. Autophagy (2010) 2.00
The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells. J Biol Chem (2007) 1.99
PAP/HIP protein is an obesogenic factor. J Cell Physiol (2014) 1.98
Methods for assessing autophagy and autophagic cell death. Methods Mol Biol (2008) 1.96
Chemotherapy and radiotherapy: cryptic anticancer vaccines. Semin Immunol (2010) 1.94
Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition. Cell Cycle (2013) 1.94