Published in PLoS One on February 01, 2013
Redox and Src family kinase signaling control leukocyte wound attraction and neutrophil reverse migration. J Cell Biol (2014) 0.85
Regulation of Monocyte Adhesion and Migration by Nox4. PLoS One (2013) 0.84
Group VIA phospholipase A2 mediates enhanced macrophage migration in diabetes mellitus by increasing expression of nicotinamide adenine dinucleotide phosphate oxidase 4. Arterioscler Thromb Vasc Biol (2014) 0.82
Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8. PLoS One (2015) 0.81
CSF1 Overexpression Promotes High-Grade Glioma Formation without Impacting the Polarization Status of Glioma-Associated Microglia and Macrophages. Cancer Res (2016) 0.78
Propofol reduces lipopolysaccharide-induced, NADPH oxidase (NOX 2) mediated TNF- α and IL-6 production in macrophages. Clin Dev Immunol (2013) 0.78
Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell Nox2 on Blood Pressure. Circulation (2017) 0.76
The complex roles of NADPH oxidases in fungal infection. Cell Microbiol (2014) 0.76
Endotoxin Disrupts Circadian Rhythms in Macrophages via Reactive Oxygen Species. PLoS One (2016) 0.75
NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury. Oxid Med Cell Longev (2017) 0.75
Rho GTPases in cell biology. Nature (2002) 22.81
NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol (2004) 12.93
NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res (2000) 8.62
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol Cell Biol (2002) 4.50
A Rac switch regulates random versus directionally persistent cell migration. J Cell Biol (2005) 4.40
Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J Biol Chem (1998) 4.05
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. J Cell Biol (2003) 4.02
Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation. Biochemistry (1998) 3.90
A role for Cdc42 in macrophage chemotaxis. J Cell Biol (1998) 3.88
Redox regulation of PI 3-kinase signalling via inactivation of PTEN. EMBO J (2003) 3.58
Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol (2006) 3.13
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res (2012) 3.02
Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol (2000) 3.01
Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation (2002) 2.57
Retracted Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circ Res (2002) 2.56
Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy. Circ Res (2003) 2.50
Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways. J Cell Sci (2003) 2.49
Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src. EMBO J (2000) 2.44
Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains? Protein Sci (1996) 2.40
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox). Nat Cell Biol (2001) 2.39
NAD(P)H oxidase mediates angiotensin II-induced vascular macrophage infiltration and medial hypertrophy. Arterioscler Thromb Vasc Biol (2003) 2.30
Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling. J Biol Chem (2001) 2.16
Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arterioscler Thromb Vasc Biol (2009) 2.01
Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice. Am J Physiol Heart Circ Physiol (2009) 2.00
Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR. J Biol Chem (2001) 1.95
Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase. FASEB J (2006) 1.90
Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration. J Cell Sci (2004) 1.88
Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Mol Cell (2004) 1.86
NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts. J Am Soc Nephrol (2009) 1.80
Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Circulation (2006) 1.72
Nox1 mediates basic fibroblast growth factor-induced migration of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2007) 1.65
PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration. Curr Biol (2007) 1.62
Redox changes of cultured endothelial cells and actin dynamics. Circ Res (2000) 1.59
Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation. Sci Signal (2009) 1.56
Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis. Circ Res (2005) 1.52
Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2. Hypertension (2010) 1.45
The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology (2011) 1.33
PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics. J Cell Sci (2008) 1.32
p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: role in NAD(P)H oxidase regulation by angiotensin II. Arterioscler Thromb Vasc Biol (2004) 1.26
Atherosclerosis is attenuated by limiting superoxide generation in both macrophages and vessel wall cells. Arterioscler Thromb Vasc Biol (2007) 1.24
Do phosphoinositide 3-kinases direct lymphocyte navigation? Trends Immunol (2004) 1.23
NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion. Circ Res (2001) 1.22
The non-provitamin A carotenoid, lutein, inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: role of H(2)O(2) in NF-kappaB activation. Free Radic Biol Med (2008) 1.19
Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells. Circ Res (2007) 1.17
NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation. Hepatology (2011) 1.15
Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species. J Biol Chem (2004) 1.09
Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors. Bioessays (2005) 1.03
Role of the actin cytoskeleton during respiratory burst in chemoattractant-stimulated neutrophils. Cell Biol Int (2006) 0.94
LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action. Immunobiology (2005) 0.93
Pulling back to move forward. Cell (2004) 0.87
Actin enhances the activation of human neutrophil NADPH oxidase in a cell-free system. Biochem Biophys Res Commun (1997) 0.83
NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation. Surgery (2003) 0.82
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science (2013) 10.87
Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc Natl Acad Sci U S A (2010) 7.77
Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Sci Transl Med (2013) 4.74
Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase. Circ Res (2012) 4.19
Bayesian localization microscopy reveals nanoscale podosome dynamics. Nat Methods (2011) 4.16
Increased myocardial NADPH oxidase activity in human heart failure. J Am Coll Cardiol (2003) 3.73
Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology. Am J Physiol Regul Integr Comp Physiol (2004) 3.27
Increased neuronal nitric oxide synthase-derived NO production in the failing human heart. Lancet (2004) 3.07
Redox signaling in cardiac physiology and pathology. Circ Res (2012) 2.98
NADPH oxidases in cardiovascular health and disease. Antioxid Redox Signal (2006) 2.95
Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha. Circ Res (2002) 2.79
Regulation of cardiac contractile function by troponin I phosphorylation. Cardiovasc Res (2005) 2.79
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration. PLoS Biol (2010) 2.72
Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation (2002) 2.57
Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy. Circ Res (2003) 2.50
Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo. Arterioscler Thromb Vasc Biol (2011) 2.44
NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis. Proc Natl Acad Sci U S A (2010) 2.36
Oxidative stress and redox signalling in cardiac hypertrophy and heart failure. Heart (2006) 2.28
Activation of NADPH oxidase during progression of cardiac hypertrophy to failure. Hypertension (2002) 2.20
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4. J Biol Chem (2011) 2.20
Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex. Nat Cell Biol (2007) 2.18
Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells. J Biol Chem (2002) 2.05
Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med (2012) 2.02
P-Rex1 regulates neutrophil function. Curr Biol (2005) 1.97
Changing characteristics and mode of death associated with chronic heart failure caused by left ventricular systolic dysfunction: a study across therapeutic eras. Circ Heart Fail (2011) 1.96
Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase. FASEB J (2006) 1.90
Activation of p38 mitogen-activated protein kinase contributes to the early cardiodepressant action of tumor necrosis factor. J Am Coll Cardiol (2006) 1.89
NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure. Cardiovasc Res (2006) 1.88
Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction. Basic Res Cardiol (2011) 1.87
Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation? Basic Res Cardiol (2011) 1.81
Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circ Res (2013) 1.81
Leptin is an endothelial-independent vasodilator in humans with coronary artery disease: Evidence for tissue specificity of leptin resistance. Eur Heart J (2006) 1.81
Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia. Blood (2006) 1.80
Nox4 and nox2 NADPH oxidases mediate distinct cellular redox signaling responses to agonist stimulation. Arterioscler Thromb Vasc Biol (2008) 1.77
The leukocyte podosome. Eur J Cell Biol (2005) 1.72
Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. J Cell Sci (2006) 1.70
Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction. Hypertension (2008) 1.68
Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane. Blood (2013) 1.65
Smooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular grafts. Circ Res (2013) 1.62
Redox signaling in cardiac myocytes. Free Radic Biol Med (2011) 1.62
Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail (2009) 1.61
Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit. J Biol Chem (2003) 1.60
Role of phosphoinositide 3-kinase {alpha}, protein kinase C, and L-type Ca2+ channels in mediating the complex actions of angiotensin II on mouse cardiac contractility. Hypertension (2010) 1.59
NADPH oxidase and endothelial cell function. Clin Sci (Lond) (2005) 1.58
IGF-binding protein-2 protects against the development of obesity and insulin resistance. Diabetes (2007) 1.56
PTEN couples Sema3A signalling to growth cone collapse. J Cell Sci (2006) 1.54
Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes. J Physiol (2002) 1.54
Effect of endothelium-specific insulin resistance on endothelial function in vivo. Diabetes (2008) 1.52
Pathological cardiac hypertrophy alters intracellular targeting of phosphodiesterase type 5 from nitric oxide synthase-3 to natriuretic peptide signaling. Circulation (2012) 1.51
Regulation of breast cancer cell chemotaxis by the phosphoinositide 3-kinase p110delta. Cancer Res (2003) 1.51
Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction. Diabetes (2013) 1.51
Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: role of p47phox phosphorylation and binding to TRAF4. Mol Cell Biol (2005) 1.50
Strain-dependent variation in vascular responses to nitric oxide in the isolated murine heart. J Mol Cell Cardiol (2002) 1.49
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia. J Exp Med (2007) 1.49
Predicting death due to progressive heart failure in patients with mild-to-moderate chronic heart failure. J Am Coll Cardiol (2002) 1.47
Inhibition of calpain stabilises podosomes and impairs dendritic cell motility. J Cell Sci (2006) 1.47
The association between saphenous vein endothelial function, systemic inflammation, and statin therapy in patients undergoing coronary artery bypass surgery. J Thorac Cardiovasc Surg (2007) 1.46
Peroxidasin-like protein: a novel peroxidase homologue in the human heart. Cardiovasc Res (2013) 1.46
ROS generation by nonphagocytic NADPH oxidase: potential relevance in diabetic nephropathy. J Am Soc Nephrol (2003) 1.45
Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse. Circ Res (2008) 1.44
WIP regulates the stability and localization of WASP to podosomes in migrating dendritic cells. Curr Biol (2006) 1.43
The emerging importance of group II PAKs. Biochem J (2010) 1.42
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail (2011) 1.40
NADPH oxidase-derived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes. Am J Pathol (2006) 1.39
Protection against endotoxemia-induced contractile dysfunction in mice with cardiac-specific expression of slow skeletal troponin I. FASEB J (2005) 1.38
A PAK4-LIMK1 pathway drives prostate cancer cell migration downstream of HGF. Cell Signal (2008) 1.38
Signalling to cancer cell invasion through PAK family kinases. Front Biosci (Landmark Ed) (2011) 1.36
Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury. Circulation (2012) 1.36
Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein. Blood (2004) 1.35
Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy. Cancer Res (2010) 1.35
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo. Circulation (2008) 1.34
Involvement of the nicotinamide adenosine dinucleotide phosphate oxidase isoform Nox2 in cardiac contractile dysfunction occurring in response to pressure overload. J Am Coll Cardiol (2006) 1.34
Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation. Circulation (2004) 1.31
Wiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cells. J Pathol (2004) 1.31
Cardiomyocytes as effectors of nitric oxide signalling. Cardiovasc Res (2007) 1.31
Maturation of DC is associated with changes in motile characteristics and adherence. Cell Motil Cytoskeleton (2004) 1.31
Role of Nox4 in murine models of kidney disease. Free Radic Biol Med (2012) 1.28
WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption. Blood (2004) 1.28
NADPH oxidases in heart failure: poachers or gamekeepers? Antioxid Redox Signal (2012) 1.27
Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo. Circulation (2009) 1.27
Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4. J Biol Chem (2011) 1.26
Involvement of NADPH oxidase in age-associated cardiac remodeling. J Mol Cell Cardiol (2010) 1.25
Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice. Nat Commun (2012) 1.25
Vascular dysfunction and reduced circulating endothelial progenitor cells in young healthy UK South Asian men. Arterioscler Thromb Vasc Biol (2007) 1.24
Cell migration in development and disease. Dev Cell (2002) 1.23
NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies. Basic Res Cardiol (2011) 1.23
Oxidative stress and endothelial dysfunction in aortas of aged spontaneously hypertensive rats by NOX1/2 is reversed by NADPH oxidase inhibition. Hypertension (2010) 1.23
Evidence for altered interleukin 18 (IL)-18 pathway in human heart failure. FASEB J (2004) 1.22