Published in Behav Brain Res on March 06, 2013
Acute brain slice methods for adult and aging animals: application of targeted patch clamp analysis and optogenetics. Methods Mol Biol (2014) 1.14
Defining inhibitory neurone function in respiratory circuits: opportunities with optogenetics? J Physiol (2014) 0.95
Neuroanatomy goes viral! Front Neuroanat (2015) 0.93
Improved methods for chronic light-based motor mapping in mice: automated movement tracking with accelerometers, and chronic EEG recording in a bilateral thin-skull preparation. Front Neural Circuits (2013) 0.89
Optogenetic approaches for functional mouse brain mapping. Front Neurosci (2013) 0.86
Suppression of motor cortical excitability in anesthetized rats by low frequency repetitive transcranial magnetic stimulation. PLoS One (2014) 0.86
Differences in social interaction- vs. cocaine reward in mouse vs. rat. Front Behav Neurosci (2014) 0.85
Genetic dissection of GABAergic neural circuits in mouse neocortex. Front Cell Neurosci (2014) 0.84
Transgenic labeling of parvalbumin-expressing neurons with tdTomato. Neuroscience (2015) 0.83
Controlling feeding behavior by chemical or gene-directed targeting in the brain: what's so spatial about our methods? Front Neurosci (2013) 0.82
A murine toolbox for imaging the neurovascular unit. Microcirculation (2015) 0.81
Optogenetic Approaches for Controlling Seizure Activity. Brain Stimul (2016) 0.78
Single body parts are processed by individual neurons in the mouse dorsolateral striatum. Brain Res (2016) 0.77
Optogenetic Modulation of Urinary Bladder Contraction for Lower Urinary Tract Dysfunction. Sci Rep (2017) 0.75
Optogenetic activation of the excitatory neurons expressing CaMKIIα in the ventral tegmental area upregulates the locomotor activity of free behaving rats. Biomed Res Int (2014) 0.75
A Chronically Implantable Bidirectional Neural Interface for Non-human Primates. Front Neurosci (2017) 0.75
Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci (2005) 28.08
Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron (2000) 22.02
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci (2009) 21.94
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature (2003) 16.48
Multimodal fast optical interrogation of neural circuitry. Nature (2007) 14.68
Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature (2009) 10.79
Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science (2009) 8.76
Germ-line transformation of mice. Annu Rev Genet (1986) 8.67
Molecular and cellular approaches for diversifying and extending optogenetics. Cell (2010) 8.43
High-performance genetically targetable optical neural silencing by light-driven proton pumps. Nature (2010) 8.37
Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature (2011) 8.25
Subregion- and cell type-restricted gene knockout in mouse brain. Cell (1996) 8.02
Optical deconstruction of parkinsonian neural circuitry. Science (2009) 7.80
In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2. Neuron (2007) 7.59
Control of memory formation through regulated expression of a CaMKII transgene. Science (1996) 7.56
Optogenetics in neural systems. Neuron (2011) 7.56
Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry. Nature (2010) 7.35
Rapid modification of bacterial artificial chromosomes by ET-recombination. Nucleic Acids Res (1999) 6.85
The development and application of optogenetics. Annu Rev Neurosci (2011) 6.84
Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nat Biotechnol (1997) 6.29
Targeting and readout strategies for fast optical neural control in vitro and in vivo. J Neurosci (2007) 6.28
Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice. Nature (2008) 6.08
Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin. Proc Natl Acad Sci U S A (2005) 5.95
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci U S A (1996) 5.93
Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J Neurosci (2007) 5.87
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (2010) 5.48
High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. Proc Natl Acad Sci U S A (2007) 5.42
Amygdala circuitry mediating reversible and bidirectional control of anxiety. Nature (2011) 5.41
Optogenetic stimulation of a hippocampal engram activates fear memory recall. Nature (2012) 5.32
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training. Nat Neurosci (2010) 4.94
A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing. Nat Neurosci (2012) 4.87
Ultrafast optogenetic control. Nat Neurosci (2010) 4.73
Bi-stable neural state switches. Nat Neurosci (2008) 4.69
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures. Nat Protoc (2010) 4.69
Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature (2011) 4.58
Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri. Nat Neurosci (2008) 4.52
Genetic dissection of an amygdala microcircuit that gates conditioned fear. Nature (2010) 4.34
Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins. Nat Methods (2011) 4.27
A disinhibitory microcircuit for associative fear learning in the auditory cortex. Nature (2011) 4.12
Dynamics of retrieval strategies for remote memories. Cell (2011) 4.04
Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function. Nat Methods (2011) 4.02
Functional identification of an aggression locus in the mouse hypothalamus. Nature (2011) 3.88
Deconstruction of a neural circuit for hunger. Nature (2012) 3.62
Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Res (2002) 3.61
eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications. Brain Cell Biol (2008) 3.60
Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron (2005) 3.54
Tuning arousal with optogenetic modulation of locus coeruleus neurons. Nat Neurosci (2010) 3.50
Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron (2011) 3.49
Cholinergic interneurons control local circuit activity and cocaine conditioning. Science (2010) 3.15
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature (2012) 3.15
Overexpression of growth-associated proteins in the neurons of adult transgenic mice. J Neurosci Methods (1997) 2.97
Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature (2012) 2.88
Crystal structure of the channelrhodopsin light-gated cation channel. Nature (2012) 2.83
Activation of VTA GABA neurons disrupts reward consumption. Neuron (2012) 2.80
A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex. Front Syst Neurosci (2011) 2.72
High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels. Proc Natl Acad Sci U S A (2011) 2.67
A wirelessly powered and controlled device for optical neural control of freely-behaving animals. J Neural Eng (2011) 2.39
Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. J Neurosci (2011) 2.37
Habenula "cholinergic" neurons co-release glutamate and acetylcholine and activate postsynaptic neurons via distinct transmission modes. Neuron (2011) 2.14
Automated light-based mapping of motor cortex by photoactivation of channelrhodopsin-2 transgenic mice. Nat Methods (2009) 2.13
Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biol (2008) 2.12
The columnar and laminar organization of inhibitory connections to neocortical excitatory cells. Nat Neurosci (2010) 1.98
Two-photon single-cell optogenetic control of neuronal activity by sculpted light. Proc Natl Acad Sci U S A (2010) 1.97
Fast synaptic subcortical control of hippocampal circuits. Science (2009) 1.93
Perception of sniff phase in mouse olfaction. Nature (2011) 1.89
Functional connectome of the striatal medium spiny neuron. J Neurosci (2011) 1.89
Visual function in mice with photoreceptor degeneration and transgenic expression of channelrhodopsin 2 in ganglion cells. J Neurosci (2010) 1.87
Mapping brain networks in awake mice using combined optical neural control and fMRI. J Neurophysiol (2010) 1.87
Non-redundant odor coding by sister mitral cells revealed by light addressable glomeruli in the mouse. Nat Neurosci (2010) 1.86
Leptin regulates the reward value of nutrient. Nat Neurosci (2011) 1.83
Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles. Nat Neurosci (2011) 1.74
Optogenetic silencing strategies differ in their effects on inhibitory synaptic transmission. Nat Neurosci (2012) 1.64
Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion. Nat Neurosci (2010) 1.63
Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice. J Neurosci (2011) 1.58
Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors. J Neurosci (2009) 1.53
Orderly recruitment of motor units under optical control in vivo. Nat Med (2010) 1.43
Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons. J Neurosci (2009) 1.38
Activation of adult-born neurons facilitates learning and memory. Nat Neurosci (2012) 1.35
Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter. PLoS One (2009) 1.33
Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. Nat Protoc (2010) 1.33
Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement. PLoS One (2012) 1.32
Optogenetic activation of basal forebrain cholinergic neurons modulates neuronal excitability and sensory responses in the main olfactory bulb. J Neurosci (2012) 1.32
In vivo Large-Scale Cortical Mapping Using Channelrhodopsin-2 Stimulation in Transgenic Mice Reveals Asymmetric and Reciprocal Relationships between Cortical Areas. Front Neural Circuits (2012) 1.30
Visual map development depends on the temporal pattern of binocular activity in mice. Nat Neurosci (2011) 1.29
Optogenetic manipulation of neural circuitry in vivo. Curr Opin Neurobiol (2011) 1.29
Temporal control of immediate early gene induction by light. PLoS One (2009) 1.26
A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. Nat Neurosci (2010) 1.25
Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity. Neuron (2012) 1.25
Reversible online control of habitual behavior by optogenetic perturbation of medial prefrontal cortex. Proc Natl Acad Sci U S A (2012) 1.24
Application of an optogenetic byway for perturbing neuronal activity via glial photostimulation. Proc Natl Acad Sci U S A (2012) 1.17
Integration of light-controlled neuronal firing and fast circuit imaging. Curr Opin Neurobiol (2007) 1.16
Generation of transgenic mice. Methods Mol Med (2004) 1.14
Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep (2012) 1.08
Light-evoked somatosensory perception of transgenic rats that express channelrhodopsin-2 in dorsal root ganglion cells. PLoS One (2012) 1.03
Long-term channelrhodopsin-2 (ChR2) expression can induce abnormal axonal morphology and targeting in cerebral cortex. Front Neural Circuits (2013) 0.95
Opto-fMRI analysis for exploring the neuronal connectivity of the hippocampal formation in rats. Neurosci Res (2012) 0.94
Dual GABAergic synaptic response of fast excitation and slow inhibition in the medial habenula of rat epithalamus. J Neurophysiol (2007) 0.84
Identification of optogenetically activated striatal medium spiny neurons by Npas4 expression. PLoS One (2012) 0.80
Optopatcher--an electrode holder for simultaneous intracellular patch-clamp recording and optical manipulation. J Neurosci Methods (2013) 0.78
Gene targeting in the mouse. Methods Mol Biol (2011) 0.77
Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature (2002) 11.85
In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2. Neuron (2007) 7.59
A transcription activator-like effector toolbox for genome engineering. Nat Protoc (2012) 6.81
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature (2011) 5.62
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. Nature (2007) 4.59
Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function. Nat Methods (2011) 4.02
Next-generation optical technologies for illuminating genetically targeted brain circuits. J Neurosci (2006) 3.95
Sustained axon regeneration induced by co-deletion of PTEN and SOCS3. Nature (2011) 3.18
Dynamic remodeling of dendritic arbors in GABAergic interneurons of adult visual cortex. PLoS Biol (2005) 2.61
Genetic evidence that relative synaptic efficacy biases the outcome of synaptic competition. Nature (2003) 2.51
Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors. Science (2013) 2.21
Habenula "cholinergic" neurons co-release glutamate and acetylcholine and activate postsynaptic neurons via distinct transmission modes. Neuron (2011) 2.14
Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biol (2008) 2.12
Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. Nat Neurosci (2003) 2.03
The primordial, blue-cone color system of the mouse retina. J Neurosci (2005) 1.94
Visual function in mice with photoreceptor degeneration and transgenic expression of channelrhodopsin 2 in ganglion cells. J Neurosci (2010) 1.87
Synaptic dynamism measured over minutes to months: age-dependent decline in an autonomic ganglion. Nat Neurosci (2003) 1.77
Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles. Nat Neurosci (2011) 1.74
The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming. J Biol Chem (2007) 1.70
Two-photon imaging reveals somatodendritic chloride gradient in retinal ON-type bipolar cells expressing the biosensor Clomeleon. Neuron (2006) 1.63
Calcium channel alpha2delta1 subunit mediates spinal hyperexcitability in pain modulation. Pain (2006) 1.61
Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures. J Neurosci (2010) 1.50
Single-neuron labeling with inducible Cre-mediated knockout in transgenic mice. Nat Neurosci (2008) 1.43
The chloride transporter Na(+)-K(+)-Cl- cotransporter isoform-1 contributes to intracellular chloride increases after in vitro ischemia. J Neurosci (2006) 1.42
Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures. Neuron (2009) 1.42
Imaging neural activity using Thy1-GCaMP transgenic mice. Neuron (2012) 1.40
Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. Neuron (2009) 1.31
Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex. Neuron (2004) 1.28
PSD93 regulates synaptic stability at neuronal cholinergic synapses. J Neurosci (2004) 1.26
Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease. Cell Rep (2012) 1.25
Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse. J Comp Neurol (2004) 1.25
Imaging synaptic inhibition in transgenic mice expressing the chloride indicator, Clomeleon. Brain Cell Biol (2008) 1.21
ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains. J Neurosci (2013) 1.20
Acute brain slice methods for adult and aging animals: application of targeted patch clamp analysis and optogenetics. Methods Mol Biol (2014) 1.14
Functional consequences of mutations in postsynaptic scaffolding proteins and relevance to psychiatric disorders. Annu Rev Neurosci (2012) 1.13
Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes. Hepatology (2002) 1.13
Neurobiology of obsessive-compulsive disorder: insights into neural circuitry dysfunction through mouse genetics. Curr Opin Neurobiol (2011) 1.07
3D-reconstruction and functional properties of GFP-positive and GFP-negative granule cells in the fascia dentata of the Thy1-GFP mouse. Hippocampus (2008) 1.06
Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors. J Biol Chem (2005) 1.05
Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder. Genome Biol (2014) 1.04
Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction. J Cell Biol (2007) 1.04
Cellular and synaptic network defects in autism. Curr Opin Neurobiol (2012) 1.02
Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses. J Neurosci (2011) 1.02
Normal midbrain dopaminergic neuron development and function in miR-133b mutant mice. J Neurosci (2012) 1.02
Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity. J Neurosci (2011) 1.02
Labeling neurons in vivo for morphological and functional studies. Curr Opin Neurobiol (2004) 1.02
Next-generation transgenic mice for optogenetic analysis of neural circuits. Front Neural Circuits (2013) 1.01
Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon. Brain Cell Biol (2008) 0.99
Cortical control of affective networks. J Neurosci (2013) 0.97
Genetic perturbation of postsynaptic activity regulates synapse elimination in developing cerebellum. Proc Natl Acad Sci U S A (2009) 0.96
Glutamatergic Synaptic Dysfunction and Obsessive-Compulsive Disorder. Curr Chem Genomics (2008) 0.95
Fluorescent labeling of newborn dentate granule cells in GAD67-GFP transgenic mice: a genetic tool for the study of adult neurogenesis. PLoS One (2010) 0.95
Optical inhibition of motor nerve and muscle activity in vivo. Muscle Nerve (2013) 0.94
Lamina-specific distribution of Synaptopodin, an actin-associated molecule essential for the spine apparatus, in identified principal cell dendrites of the mouse hippocampus. J Comp Neurol (2005) 0.93
Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and behavioral hypersensitivity. Mol Pain (2009) 0.91
Intersectional Cre driver lines generated using split-intein mediated split-Cre reconstitution. Sci Rep (2012) 0.88
LNX1 is a perisynaptic Schwann cell specific E3 ubiquitin ligase that interacts with ErbB2. Mol Cell Neurosci (2005) 0.87
In vivo imaging of juxtaglomerular neuron turnover in the mouse olfactory bulb. Proc Natl Acad Sci U S A (2006) 0.87
Pulse labeling and long-term tracing of newborn neurons in the adult subgranular zone. Cell Res (2010) 0.87
Imaging synaptic inhibition with the genetically encoded chloride indicator Clomeleon. Cold Spring Harb Protoc (2011) 0.86
Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders. J Child Psychol Psychiatry (2011) 0.84
Corrigendum: Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures. Nat Commun (2016) 0.80
SnapShot: Autism and the synapse. Cell (2011) 0.79
Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism. J Clin Invest (2017) 0.78
Complete deletion of all alpha-dystrobrevin isoforms does not reveal new neuromuscular junction phenotype. Gene Expr (2007) 0.77
Striatal magnetic resonance spectroscopy abnormalities in young adult SAPAP3 knockout mice. Biol Psychiatry Cogn Neurosci Neuroimaging (2016) 0.76
Bactericidal thurincin H causes unique morphological changes in Bacillus cereus F4552 without affecting membrane permeability. FEMS Microbiol Lett (2014) 0.76
Neuroscience: When lights take the circuits out. Nature (2011) 0.75
Unfolding neurodevelopmental disorders: found in translation. Nat Med (2011) 0.75
Addendum: A viral strategy for targeting and manipulating interneurons across vertebrate species. Nat Neurosci (2017) 0.75
[One-stage surgical treatment of congenital blepharophimosis syndrome]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2007) 0.75
[Application of facial tissue expander fibrous envelope for tension reduction]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2012) 0.75
Corrigendum: Opportunities and challenges in modeling human brain disorders in transgenic primates. Nat Neurosci (2017) 0.75
[An experimental study on chemically induced animal model of goat cleft palate in uterus]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2011) 0.75
[Effect of in-utero surgical repair at different stages on mid-facial development of goats with cleft palate]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2011) 0.75
Reduction of patulin in apple cider by UV radiation. J Food Prot (2010) 0.75
[Adhesive deformity from the upper eyelid fold formation and its treatment]. Zhonghua Zheng Xing Wai Ke Za Zhi (2002) 0.75
[Animal model of goat cleft palate made by uterine cavitary operations]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2010) 0.75
Corrigendum: A viral strategy for targeting and manipulating interneurons across vertebrate species. Nat Neurosci (2017) 0.75