Published in Gut on July 11, 2013
The gut microbiota and host health: a new clinical frontier. Gut (2015) 1.91
Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer. Nat Commun (2014) 1.47
Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis. Gut (2015) 1.17
Gut microbiota imbalance and colorectal cancer. World J Gastroenterol (2016) 0.99
Fusobacterium and Enterobacteriaceae: important players for CRC? Immunol Lett (2014) 0.98
Microbial imbalance and intestinal pathologies: connections and contributions. Dis Model Mech (2014) 0.96
Escherichia coli from Crohn's disease patient displays virulence features of enteroinvasive (EIEC), enterohemorragic (EHEC), and enteroaggregative (EAEC) pathotypes. Gut Pathog (2015) 0.95
Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease. Sci Rep (2015) 0.90
Escherichia coli in chronic inflammatory bowel diseases: An update on adherent invasive Escherichia coli pathogenicity. World J Gastrointest Pathophysiol (2014) 0.88
Bacterial Genotoxins: Merging the DNA Damage Response into Infection Biology. Biomolecules (2015) 0.86
The therapeutic value of targeting inflammation in gastrointestinal cancers. Trends Pharmacol Sci (2014) 0.86
Pathogenesis of Crohn's disease: Bug or no bug. World J Gastrointest Pathophysiol (2015) 0.84
Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer. Infect Agent Cancer (2016) 0.83
Maternally acquired genotoxic Escherichia coli alters offspring's intestinal homeostasis. Gut Microbes (2014) 0.83
The detection of the methylated Wif-1 gene is more accurate than a fecal occult blood test for colorectal cancer screening. PLoS One (2014) 0.80
Recent advancement in understanding colitis-associated tumorigenesis. Inflamm Bowel Dis (2014) 0.79
Pathogenesis of human diffusely adhering Escherichia coli expressing Afa/Dr adhesins (Afa/Dr DAEC): current insights and future challenges. Clin Microbiol Rev (2014) 0.79
Diet, Microbiota, Obesity, and NAFLD: A Dangerous Quartet. Int J Mol Sci (2016) 0.78
A Preliminary Study Examining the Binding Capacity of Akkermansia muciniphila and Desulfovibrio spp., to Colonic Mucin in Health and Ulcerative Colitis. PLoS One (2015) 0.77
From promotion to management: the wide impact of bacteria on cancer and its treatment. Bioessays (2014) 0.76
Dietary Emulsifier-Induced Low-Grade Inflammation Promotes Colon Carcinogenesis. Cancer Res (2016) 0.75
Association of colorectal cancer with pathogenic Escherichia coli: Focus on mechanisms using optical imaging. World J Clin Oncol (2016) 0.75
Killing of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D. Inflamm Bowel Dis (2015) 0.75
Increased Enterococcus faecalis infection is associated with clinically active Crohn disease. Medicine (Baltimore) (2016) 0.75
Revealing potential molecular targets bridging colitis and colorectal cancer based on multidimensional integration strategy. Oncotarget (2015) 0.75
Current Hypothesis for the Relationship between Dietary Rice Bran Intake, the Intestinal Microbiota and Colorectal Cancer Prevention. Nutrients (2016) 0.75
Association of oncogenic bacteria with colorectal cancer in South China. Oncotarget (2016) 0.75
Clonal evolution of colorectal cancer in IBD. Nat Rev Gastroenterol Hepatol (2017) 0.75
Escherichia coli-host macrophage interactions in the pathogenesis of inflammatory bowel disease. World J Gastroenterol (2014) 0.75
Commensal bacterial internalization by epithelial cells: An alternative portal for gut leakiness. Tissue Barriers (2015) 0.75
Cancer associated faecal microbial markers in colorectal cancer detection. Int J Cancer (2017) 0.75
Alteration of Esophageal Microbiome by Antibiotic Treatment Does Not Affect Incidence of Rat Esophageal Adenocarcinoma. Dig Dis Sci (2016) 0.75
Epithelial-mesenchymal transitions in development and disease. Cell (2009) 39.17
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell (2004) 15.82
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat Immunol (2001) 11.07
Mucosal flora in inflammatory bowel disease. Gastroenterology (2002) 8.42
Intestinal inflammation targets cancer-inducing activity of the microbiota. Science (2012) 7.54
Patterns of adherence of diarrheagenic Escherichia coli to HEp-2 cells. Pediatr Infect Dis J (1987) 7.15
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology (2004) 5.94
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science (2007) 5.54
Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease. Gastroenterology (1998) 5.02
Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer. Gastroenterology (2004) 4.89
Molecular characterization of a fimbrial adhesin, F1845, mediating diffuse adherence of diarrhea-associated Escherichia coli to HEp-2 cells. J Bacteriol (1989) 4.37
Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. Nature (2009) 3.18
Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflamm Bowel Dis (2009) 2.85
Molecular characterization of rectal mucosa-associated bacterial flora in inflammatory bowel disease. Inflamm Bowel Dis (2005) 2.47
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Invest (2007) 2.44
High prevalence of Escherichia coli belonging to the B2+D phylogenetic group in inflammatory bowel disease. Gut (2006) 2.43
Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis. Inflamm Bowel Dis (2006) 2.38
Genetic organization of the afimbrial adhesin operon and nucleotide sequence from a uropathogenic Escherichia coli gene encoding an afimbrial adhesin. J Bacteriol (1985) 2.32
Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death. Infect Immun (2001) 2.28
Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared. Trends Mol Med (2002) 2.24
Association between intraepithelial Escherichia coli and colorectal cancer. Gastroenterology (1998) 2.15
Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae. J Clin Invest (2011) 2.10
Adhesion and entry of uropathogenic Escherichia coli. Cell Microbiol (2002) 1.97
Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease. Inflamm Bowel Dis (2009) 1.88
Identification of GP2, the major zymogen granule membrane glycoprotein, as the autoantigen of pancreatic antibodies in Crohn's disease. Gut (2009) 1.86
Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers. Gut (2010) 1.77
Complete genome sequence of Crohn's disease-associated adherent-invasive E. coli strain LF82. PLoS One (2010) 1.69
Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease. Inflamm Bowel Dis (2007) 1.63
Evidence for a role of epithelial mesenchymal transition during pathogenesis of fistulae in Crohn's disease. Inflamm Bowel Dis (2008) 1.61
Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J Biol Chem (2010) 1.58
Pathogenesis of Afa/Dr diffusely adhering Escherichia coli. Clin Microbiol Rev (2005) 1.51
M cells as ports of entry for enteroinvasive pathogens: mechanisms of interaction, consequences for the disease process. Semin Immunol (1999) 1.51
High prevalence of mucosa-associated E. coli producing cyclomodulin and genotoxin in colon cancer. PLoS One (2013) 1.50
VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer. J Exp Med (2010) 1.45
Dr fimbriae operon of uropathogenic Escherichia coli mediate microtubule-dependent invasion to the HeLa epithelial cell line. J Infect Dis (1997) 1.43
Bacterial DNA within granulomas of patients with Crohn's disease--detection by laser capture microdissection and PCR. Am J Gastroenterol (2004) 1.21
Characterization of AfaE adhesins produced by extraintestinal and intestinal human Escherichia coli isolates: PCR assays for detection of Afa adhesins that do or do not recognize Dr blood group antigens. J Clin Microbiol (2001) 1.06
Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. Antimicrob Agents Chemother (2007) 1.01
Decay-accelerating factor (DAF, CD55) in normal colorectal mucosa, adenomas and carcinomas. Br J Cancer (1992) 0.99
Nonlethal adherence to human neutrophils mediated by Dr antigen-specific adhesins of Escherichia coli. Infect Immun (1995) 0.98
HIF-1alpha mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-like behaviour. Cell Microbiol (2009) 0.97
The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing. J Bacteriol (2007) 0.97
Expression of cell membrane complement regulatory glycoproteins along the normal and diseased human gastrointestinal tract. Gut (1998) 0.96
Diffusely adherent Escherichia coli strains expressing Afa/Dr adhesins (Afa/Dr DAEC): hitherto unrecognized pathogens. FEMS Microbiol Lett (2006) 0.96
Characterization of Escherichia coli isolated from gut biopsies of newly diagnosed patients with inflammatory bowel disease. Inflamm Bowel Dis (2010) 0.96
HtrA stress protein is involved in intramacrophagic replication of adherent and invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease. Infect Immun (2005) 0.94
Increased rate of apoptosis and diminished phagocytic ability of human neutrophils infected with Afa/Dr diffusely adhering Escherichia coli strains. Infect Immun (2004) 0.90
Bacteria in the pathogenesis of inflammatory bowel disease. Biochem Soc Trans (2011) 0.89
Early vascular changes in Crohn's disease: an endoscopic fluorescence study. Endoscopy (2000) 0.82
Characterization of lymphoid follicles with red ring signs as first manifestation of early Crohn's disease by conventional histopathology and confocal laser endomicroscopy. Int J Clin Exp Pathol (2012) 0.81
Abnormal CEACAM6 expression in Crohn disease patients favors gut colonization and inflammation by adherent-invasive E. coli. Virulence (2010) 0.79
Genome sequence of the human malaria parasite Plasmodium falciparum. Nature (2002) 37.89
Accurate determination of microbial diversity from 454 pyrosequencing data. Nat Methods (2009) 15.25
The genome of the African trypanosome Trypanosoma brucei. Science (2005) 11.48
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature (2005) 8.55
Intestinal inflammation targets cancer-inducing activity of the microbiota. Science (2012) 7.54
Gut microbiota composition correlates with diet and health in the elderly. Nature (2012) 6.94
GeneDB: a resource for prokaryotic and eukaryotic organisms. Nucleic Acids Res (2004) 6.30
Analysis of the bread wheat genome using whole-genome shotgun sequencing. Nature (2012) 5.67
Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry. Nature (2002) 5.48
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med (2009) 5.43
Comparative genomics of trypanosomatid parasitic protozoa. Science (2005) 5.37
The genome of the protist parasite Entamoeba histolytica. Nature (2005) 5.33
Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci U S A (2010) 5.02
Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine. PLoS One (2009) 4.93
Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer. Gastroenterology (2004) 4.89
Regulation of sexual development of Plasmodium by translational repression. Science (2006) 4.15
Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk. Gut (2011) 3.42
An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm. Proc Natl Acad Sci U S A (2005) 3.06
Pseudomonas genomes: diverse and adaptable. FEMS Microbiol Rev (2011) 2.96
Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease. J Clin Microbiol (2006) 2.93
Pseudomonas aeruginosa population diversity and turnover in cystic fibrosis chronic infections. Am J Respir Crit Care Med (2011) 2.88
Antagonistic coevolution accelerates molecular evolution. Nature (2010) 2.80
Diversity of bifidobacteria within the infant gut microbiota. PLoS One (2012) 2.71
Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes. Science (2005) 2.71
Randomised placebo-controlled trial of rituximab (anti-CD20) in active ulcerative colitis. Gut (2011) 2.68
A transcriptomic analysis of the phylum Nematoda. Nat Genet (2004) 2.68
A randomized controlled trial of Licartin for preventing hepatoma recurrence after liver transplantation. Hepatology (2007) 2.66
Comparative genomics of transcriptional control in the human malaria parasite Plasmodium falciparum. Genome Res (2004) 2.66
A bacterial driver-passenger model for colorectal cancer: beyond the usual suspects. Nat Rev Microbiol (2012) 2.56
Genome of the host-cell transforming parasite Theileria annulata compared with T. parva. Science (2005) 2.55
Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome. Proc Natl Acad Sci U S A (2008) 2.53
Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses. Biol Psychiatry (2008) 2.52
Towards the human colorectal cancer microbiome. PLoS One (2011) 2.30
Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared. Trends Mol Med (2002) 2.24
Transcript-specific, single-nucleotide polymorphism discovery and linkage analysis in hexaploid bread wheat (Triticum aestivum L.). Plant Biotechnol J (2011) 2.13
Plasmodium falciparum variant surface antigen expression patterns during malaria. PLoS Pathog (2005) 2.13
Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae. J Clin Invest (2011) 2.10
Distribution of type III secretion gene clusters in Burkholderia pseudomallei, B. thailandensis and B. mallei. J Med Microbiol (2002) 2.06
A Plasmodium whole-genome synteny map: indels and synteny breakpoints as foci for species-specific genes. PLoS Pathog (2005) 2.05
Divergent, coexisting Pseudomonas aeruginosa lineages in chronic cystic fibrosis lung infections. Am J Respir Crit Care Med (2015) 2.00
Application of next-generation sequencing technologies in virology. J Gen Virol (2012) 1.98
The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults. Front Cell Infect Microbiol (2013) 1.87
Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion. J Biol Chem (2006) 1.84
Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers. Gut (2010) 1.77
A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. J Bacteriol (2005) 1.74
Horizontal gene transfer facilitated the evolution of plant parasitic mechanisms in the oomycetes. Proc Natl Acad Sci U S A (2011) 1.71
Micro-eukaryotic diversity of the human distal gut microbiota: qualitative assessment using culture-dependent and -independent analysis of faeces. ISME J (2008) 1.70
Metabonomic and microbiological analysis of the dynamic effect of vancomycin-induced gut microbiota modification in the mouse. J Proteome Res (2008) 1.67
Analysis of tissue-specific differentially methylated regions (TDMs) in humans. Genomics (2006) 1.60
Inferring the human microRNA functional similarity and functional network based on microRNA-associated diseases. Bioinformatics (2010) 1.59
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development. BMC Genomics (2011) 1.56
Human methanogen diversity and incidence in healthy and diseased colonic groups using mcrA gene analysis. BMC Microbiol (2008) 1.56
Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk. Cell Metab (2012) 1.55
The intestinal protozoan parasite Entamoeba histolytica contains 20 cysteine protease genes, of which only a small subset is expressed during in vitro cultivation. Eukaryot Cell (2003) 1.51
Transposon-aided capture (TRACA) of plasmids resident in the human gut mobile metagenome. Nat Methods (2006) 1.50
HAb18G/CD147 functions in invasion and metastasis of hepatocellular carcinoma. Mol Cancer Res (2007) 1.48
Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury. Circulation (2006) 1.48
Escherichia coli-mediated impairment of ureteric contractility is uropathogenic E. coli specific. J Infect Dis (2012) 1.48
Transmissible strains of Pseudomonas aeruginosa in cystic fibrosis lung infections. Eur Respir J (2012) 1.46
Novel mutations of the FRMD7 gene in X-linked congenital motor nystagmus. Mol Vis (2007) 1.45
Retracted Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy. Diabetes (2007) 1.44
Microbiomic analysis of the bifidobacterial population in the human distal gut. ISME J (2009) 1.43
Widespread pyocyanin over-production among isolates of a cystic fibrosis epidemic strain. BMC Microbiol (2007) 1.43
Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis. Environ Microbiol (2008) 1.42
Fluctuations in phenotypes and genotypes within populations of Pseudomonas aeruginosa in the cystic fibrosis lung during pulmonary exacerbations. J Med Microbiol (2009) 1.41
A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome. Dig Dis Sci (2009) 1.39
Oral contraceptives and Crohn's disease. Gut (2013) 1.39
Complete Genome Sequence of the Arcobacter butzleri Cattle Isolate 7h1h. Genome Announc (2013) 1.39
Gene synteny and evolution of genome architecture in trypanosomatids. Mol Biochem Parasitol (2004) 1.36
Targeted re-sequencing of the allohexaploid wheat exome. Plant Biotechnol J (2012) 1.35
Sex differences in experimental autoimmune encephalomyelitis in multiple murine strains. J Neuroimmunol (2004) 1.34
The genetic map and comparative analysis with the physical map of Trypanosoma brucei. Nucleic Acids Res (2005) 1.33
Insight into the genome of Aspergillus fumigatus: analysis of a 922 kb region encompassing the nitrate assimilation gene cluster. Fungal Genet Biol (2004) 1.33
Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse. Diabetes (2010) 1.32
Marine metagenomics: strategies for the discovery of novel enzymes with biotechnological applications from marine environments. Microb Cell Fact (2008) 1.32
The genome of model malaria parasites, and comparative genomics. Curr Issues Mol Biol (2005) 1.32
Culture-independent analysis of desulfovibrios in the human distal colon of healthy, colorectal cancer and polypectomized individuals. FEMS Microbiol Ecol (2009) 1.31
Isolation and analysis of bacteria with antimicrobial activities from the marine sponge Haliclona simulans collected from Irish waters. Mar Biotechnol (NY) (2008) 1.30
Species variation in the fecal metabolome gives insight into differential gastrointestinal function. J Proteome Res (2007) 1.30
RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model. Am J Physiol Heart Circ Physiol (2008) 1.29
Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii. Genome Res (2006) 1.28
GeMInA, Genomic Metadata for Infectious Agents, a geospatial surveillance pathogen database. Nucleic Acids Res (2009) 1.27
Persistent and aggressive bacteria in the lungs of cystic fibrosis children. Br Med Bull (2002) 1.27
Liver transplantation as a cure for acute intermittent porphyria. Lancet (2004) 1.26
Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface. Cancer Res (2009) 1.26
Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis. Mol Cancer (2010) 1.23
The diversity of Rab GTPases in Entamoeba histolytica. Exp Parasitol (2005) 1.23
Targeting radioimmunotherapy of hepatocellular carcinoma with iodine (131I) metuximab injection: clinical phase I/II trials. Int J Radiat Oncol Biol Phys (2006) 1.23
Unique organisation of tRNA genes in Entamoeba histolytica. Mol Biochem Parasitol (2005) 1.22
A case for a Glossina genome project. Trends Parasitol (2005) 1.22
Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium. Clin Cancer Res (2011) 1.21
Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages. J Bacteriol (2009) 1.21
Diversity of microbes associated with the marine sponge, Haliclona simulans, isolated from Irish waters and identification of polyketide synthase genes from the sponge metagenome. Environ Microbiol (2008) 1.20
The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei. Mol Biochem Parasitol (2002) 1.20
A new, expressed multigene family containing a hot spot for insertion of retroelements is associated with polymorphic subtelomeric regions of Trypanosoma brucei. Eukaryot Cell (2002) 1.19
Arabidopsis thaliana leaf form evolved via loss of KNOX expression in leaves in association with a selective sweep. Curr Biol (2010) 1.19