Published in Proc Natl Acad Sci U S A on November 04, 2013
Mechanisms of antibiotic resistance in enterococci. Expert Rev Anti Infect Ther (2014) 0.97
Retrocyclins neutralize bacterial toxins by potentiating their unfolding. Biochem J (2015) 0.85
Visualizing attack of Escherichia coli by the antimicrobial peptide human defensin 5. Biochemistry (2015) 0.84
Lights, Camera, Action! Antimicrobial Peptide Mechanisms Imaged in Space and Time. Trends Microbiol (2015) 0.81
Amplifying renal immunity: the role of antimicrobial peptides in pyelonephritis. Nat Rev Nephrol (2015) 0.80
A bacterial mutant library as a tool to study the attack of a defensin peptide. Chembiochem (2014) 0.80
Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA. J Clin Invest (2016) 0.78
Focal Targeting of the Bacterial Envelope by Antimicrobial Peptides. Front Cell Dev Biol (2016) 0.78
Antimicrobial Peptides Targeting Gram-Positive Bacteria. Pharmaceuticals (Basel) (2016) 0.77
PrgU: A Suppressor of Sex Pheromone Toxicity in Enterococcus faecalis. Mol Microbiol (2016) 0.77
Comprehensive analysis of phospholipids and glycolipids in the opportunistic pathogen Enterococcus faecalis. PLoS One (2017) 0.75
Oligopolyphenylenevinylene-conjugated oligoelectrolyte membrane insertion molecules selectively disrupt cell envelopes of Gram-positive bacteria. Appl Environ Microbiol (2015) 0.75
Dual defensin strategy for targeting Enterococcus faecalis. Proc Natl Acad Sci U S A (2013) 0.75
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol (2005) 13.69
Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol (2003) 11.11
Induced cell aggregation and mating in Streptococcus faecalis: evidence for a bacterial sex pheromone. Proc Natl Acad Sci U S A (1978) 9.67
Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic. Science (1999) 5.30
Cytokinesis in bacteria. Microbiol Mol Biol Rev (2003) 5.29
Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine. J Exp Med (2001) 5.06
Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria. Microbiol Mol Biol Rev (2006) 4.88
The co-evolution of host cationic antimicrobial peptides and microbial resistance. Nat Rev Microbiol (2006) 4.29
Bacterial cell wall synthesis: new insights from localization studies. Microbiol Mol Biol Rev (2005) 3.72
Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J Clin Invest (1998) 3.51
Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections. Proc Natl Acad Sci U S A (2000) 3.46
An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II. Science (2006) 3.05
Lipid II as a target for antibiotics. Nat Rev Drug Discov (2006) 3.01
Visualization of phospholipid domains in Escherichia coli by using the cardiolipin-specific fluorescent dye 10-N-nonyl acridine orange. J Bacteriol (2000) 2.64
Subcellular sites for bacterial protein export. Mol Microbiol (2004) 2.50
Spatial control of bacterial division-site placement. Nat Rev Microbiol (2005) 2.43
Quantitative genome-scale analysis of protein localization in an asymmetric bacterium. Proc Natl Acad Sci U S A (2009) 2.33
Cardiolipin domains in Bacillus subtilis marburg membranes. J Bacteriol (2004) 1.98
PSICIC: noise and asymmetry in bacterial division revealed by computational image analysis at sub-pixel resolution. PLoS Comput Biol (2008) 1.88
Antimicrobial peptide resistance mechanisms of human bacterial pathogens. Curr Issues Mol Biol (2006) 1.87
A microdomain for protein secretion in Gram-positive bacteria. Science (2004) 1.84
Phosphatidylglycerol is involved in protein translocation across Escherichia coli inner membranes. Nature (1988) 1.71
RNA-dependent lipid remodeling by bacterial multiple peptide resistance factors. Proc Natl Acad Sci U S A (2008) 1.70
The MprF protein is required for lysinylation of phospholipids in listerial membranes and confers resistance to cationic antimicrobial peptides (CAMPs) on Listeria monocytogenes. Mol Microbiol (2006) 1.68
Human defensins. J Mol Med (Berl) (2005) 1.66
Signal sequence directs localized secretion of bacterial surface proteins. Nature (2006) 1.57
Human beta-defensin 3 inhibits cell wall biosynthesis in Staphylococci. Infect Immun (2010) 1.48
Induction of group A Streptococcus virulence by a human antimicrobial peptide. Proc Natl Acad Sci U S A (2008) 1.45
Development of a mariner-based transposon and identification of Listeria monocytogenes determinants, including the peptidyl-prolyl isomerase PrsA2, that contribute to its hemolytic phenotype. J Bacteriol (2009) 1.31
The action of cardiolipin on the bacterial translocon. Proc Natl Acad Sci U S A (2010) 1.30
Nisin-induced changes in Bacillus morphology suggest a paradigm of antibiotic action. Proc Natl Acad Sci U S A (2006) 1.30
Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice. Infect Immun (2005) 1.26
Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II. FEBS Lett (2010) 1.26
Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis. J Bacteriol (2009) 1.23
Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content. PLoS One (2012) 1.23
Sortase A localizes to distinct foci on the Streptococcus pyogenes membrane. Proc Natl Acad Sci U S A (2008) 1.20
Anionic lipids enriched at the ExPortal of Streptococcus pyogenes. J Bacteriol (2006) 1.14
Phosphatidic acid and N-acylphosphatidylethanolamine form membrane domains in Escherichia coli mutant lacking cardiolipin and phosphatidylglycerol. J Biol Chem (2008) 1.12
Broad range amino acid specificity of RNA-dependent lipid remodeling by multiple peptide resistance factors. J Biol Chem (2009) 1.10
The Bacillus anthracis protein MprF is required for synthesis of lysylphosphatidylglycerols and for resistance to cationic antimicrobial peptides. J Bacteriol (2008) 1.05
Acyl enzyme intermediates in sortase-catalyzed pilus morphogenesis in gram-positive bacteria. J Bacteriol (2009) 1.04
The role of lipids in membrane insertion and translocation of bacterial proteins. Biochim Biophys Acta (2004) 1.02
Different subcellular locations of secretome components of Gram-positive bacteria. Microbiology (2006) 0.97
Sec translocase and sortase A are colocalised in a locus in the cytoplasmic membrane of Streptococcus mutans. Arch Oral Biol (2007) 0.94
Impairment of innate immune killing mechanisms by bacteriostatic antibiotics. FASEB J (2007) 0.94
Cationic antimicrobial peptides disrupt the Streptococcus pyogenes ExPortal. Mol Microbiol (2012) 0.89
Role of mprF1 and mprF2 in the pathogenicity of Enterococcus faecalis. PLoS One (2012) 0.86
SecA localization and SecA-dependent secretion occurs at new division septa in group B Streptococcus. PLoS One (2013) 0.80
Intracellular bacterial biofilm-like pods in urinary tract infections. Science (2003) 7.10
Role of Escherichia coli curli operons in directing amyloid fiber formation. Science (2002) 5.58
Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. Proc Natl Acad Sci U S A (2006) 5.13
Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A (2004) 4.12
Mitochondrial transcription factor A regulates mtDNA copy number in mammals. Hum Mol Genet (2004) 4.11
The biology and future prospects of antivirulence therapies. Nat Rev Microbiol (2008) 3.83
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet (2002) 3.78
An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps. Curr Biol (2006) 3.69
Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med (2007) 3.54
Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract. Proc Natl Acad Sci U S A (2006) 3.36
Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol Microbiol (2002) 3.26
Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome. Cell Metab (2009) 3.06
Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin. Science (2004) 3.06
Clinical and microbiological characteristics of severe Streptococcus pyogenes disease in Europe. J Clin Microbiol (2009) 2.80
MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell (2007) 2.76
Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell (2008) 2.69
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences. Proc Natl Acad Sci U S A (2014) 2.63
Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell (2002) 2.54
Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med (2002) 2.53
Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol (2009) 2.52
Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili. Cell Microbiol (2007) 2.48
Bacterial adhesins in host-microbe interactions. Cell Host Microbe (2009) 2.43
Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli. J Biol Chem (2001) 2.34
Bacterial strategies for overcoming host innate and adaptive immune responses. Nat Immunol (2002) 2.33
Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients. Blood (2007) 2.32
Morphological plasticity as a bacterial survival strategy. Nat Rev Microbiol (2008) 2.28
Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli. Infect Immun (2002) 2.20
Structural biology of the chaperone-usher pathway of pilus biogenesis. Nat Rev Microbiol (2009) 2.19
The Salmonella enterica subspecies I specific centisome 7 genomic island encodes novel protein families present in bacteria living in close contact with eukaryotic cells. Res Microbiol (2002) 2.18
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17
Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci Transl Med (2011) 2.16
Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A (2006) 2.15
A murine model of urinary tract infection. Nat Protoc (2009) 2.15
Secretion of curli fibre subunits is mediated by the outer membrane-localized CsgG protein. Mol Microbiol (2006) 2.14
Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation. Infect Immun (2006) 2.11
Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies. J Exp Med (2007) 2.11
Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization. Infect Immun (2005) 2.10
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. J Biol Chem (2005) 2.06
Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells. J Exp Med (2003) 2.05
Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2003) 2.02
Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol (2007) 2.02
A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis. Proc Natl Acad Sci U S A (2006) 2.01
Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps. Cell Microbiol (2007) 1.99
Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli. Microbes Infect (2010) 1.95
Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity. Am J Hum Genet (2012) 1.94
Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Mol Microbiol (2005) 1.90
LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs. EMBO J (2011) 1.89
Fiber assembly by the chaperone-usher pathway. Biochim Biophys Acta (2004) 1.89
Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury. J Invest Dermatol (2010) 1.89
Genomic diversity and fitness of E. coli strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection. Sci Transl Med (2013) 1.88
Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. PLoS Pathog (2010) 1.88
Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A (2006) 1.87
Clinical utility of PCR for common viruses in acute respiratory illness. Pediatrics (2014) 1.86
Patterns of virulence gene expression differ between biofilm and tissue communities of Streptococcus pyogenes. Mol Microbiol (2005) 1.86
Intraclonal variations among Streptococcus pneumoniae isolates influence the likelihood of invasive disease in children. J Infect Dis (2013) 1.84
Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli. PLoS Pathog (2009) 1.83
Polynucleotide phosphorylase is a global regulator of virulence and persistency in Salmonella enterica. Proc Natl Acad Sci U S A (2002) 1.83
Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein. J Urol (2004) 1.82
Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Mol Cell (2006) 1.81
Epidemiology of severe Streptococcus pyogenes disease in Europe. J Clin Microbiol (2008) 1.81
Neutrophil extracellular traps: casting the NET over pathogenesis. Curr Opin Microbiol (2007) 1.80
A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. J Infect Dis (2013) 1.76
Comparative functional analysis of the lac operons in Streptococcus pyogenes. Mol Microbiol (2007) 1.74
Epidermal EGFR controls cutaneous host defense and prevents inflammation. Sci Transl Med (2013) 1.69
The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis. Endocrinology (2005) 1.69
MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome. Cell Metab (2011) 1.68
Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature (2011) 1.67
The frequency and rate of pilin antigenic variation in Neisseria gonorrhoeae. Mol Microbiol (2005) 1.65
Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration. Proc Natl Acad Sci U S A (2002) 1.65
Functional genomic studies of uropathogenic Escherichia coli and host urothelial cells when intracellular bacterial communities are assembled. J Biol Chem (2007) 1.64
Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection. Infect Immun (2012) 1.64
Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium. Proc Natl Acad Sci U S A (2002) 1.63
Clinical and pathological characterization of Mesoamerican nephropathy: a new kidney disease in Central America. Am J Kidney Dis (2013) 1.62
Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection. Cell Microbiol (2006) 1.62
Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis. Trends Microbiol (2004) 1.62
Emergence of hypervirulent mutants resistant to early clearance during systemic serotype 1 pneumococcal infection in mice and humans. J Infect Dis (2014) 1.62
Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice. Cell Microbiol (2005) 1.59
The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A (2005) 1.58
Maturation of intracellular Escherichia coli communities requires SurA. Infect Immun (2006) 1.56
Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding. Proc Natl Acad Sci U S A (2009) 1.56
Vitrification versus controlled-rate freezing in cryopreservation of human ovarian tissue. Hum Reprod (2009) 1.55
Production of endogenous antibiotics in articular cartilage. Arthritis Rheum (2004) 1.55
Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli. Infect Immun (2005) 1.55
Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiol Rev (2012) 1.55
A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts. Proc Natl Acad Sci U S A (2004) 1.53
Virulence in mice of pneumococcal clonal types with known invasive disease potential in humans. J Infect Dis (2005) 1.51
Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection. Cell Host Microbe (2009) 1.51
Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle. FEBS Lett (2007) 1.50