Chemical characterization of products of the H-2 complex.

Analysis of H-2 and Ia molecules by two-dimensional gel electrophoresis. J Exp Med (1977) 3.26

Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules. J Exp Med (1982) 2.15

Murine Ia and human DR antigens: homology of amino-terminal sequences. Proc Natl Acad Sci U S A (1978) 1.70

Structure of murine Ia antigens: partial NH2-terminal amino acid sequences of products of the I-E or I-C subregion. Proc Natl Acad Sci U S A (1977) 1.56

Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex. Proc Natl Acad Sci U S A (1977) 1.09

Complete amino acid sequence of pooled papain-solubilized HLA-A, -B, and -C antigens: relatedness to immunoglobulins and internal homologies. Proc Natl Acad Sci U S A (1980) 1.06

Immunochemical evidence for three Ia loci in the I-region of the H-2 complex. J Exp Med (1977) 0.96

Amino acid sequence of an immunoglobulin-like HLA antigen heavy chain domain. Proc Natl Acad Sci U S A (1979) 0.92

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

A common language for physical mapping of the human genome. Science (1989) 17.36

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science (2001) 17.11

The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum (1987) 14.21

A physical map of the human genome. Nature (2001) 12.39

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. Cell (1980) 10.35

Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways. Cell (1980) 9.86

DNA diagnostics--molecular techniques and automation. Science (1988) 8.85

Gene families: the taxonomy of protein paralogs and chimeras. Science (1997) 8.80

A new approach to decoding life: systems biology. Annu Rev Genomics Hum Genet (2001) 7.79

A ligase-mediated gene detection technique. Science (1988) 7.61

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet (1997) 6.66

Two mRNAs with different 3' ends encode membrane-bound and secreted forms of immunoglobulin mu chain. Cell (1980) 6.32

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody. Cell (1981) 5.87

Genome sequence of Halobacterium species NRC-1. Proc Natl Acad Sci U S A (2000) 5.87

The organization, expression, and evolution of antibody genes and other multigene families. Annu Rev Genet (1975) 5.87

A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Cell (1981) 5.43

High survival rates of kidney transplants from spousal and living unrelated donors. N Engl J Med (1995) 5.41

A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature (1982) 5.12

Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes. Cell (1981) 4.95

Pairwise end sequencing: a unified approach to genomic mapping and sequencing. Genomics (1995) 4.83

Clusters of genes encoding mouse transplantation antigens. Cell (1982) 4.71

Antibody diversity: somatic hypermutation of rearranged VH genes. Cell (1981) 4.65

A new strategy for genome sequencing. Nature (1996) 4.61

Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell (1993) 4.59

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell (1988) 4.47

Genes of the major histocompatibility complex of the mouse. Annu Rev Immunol (1983) 4.44

An immunoglobulin heavy-chain gene is formed by at least two recombinational events. Nature (1980) 3.99

Striking sequence similarity over almost 100 kilobases of human and mouse T-cell receptor DNA. Nat Genet (1994) 3.88

IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts. Nature (1981) 3.86

Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. Cancer Res (1999) 3.79

Confidence limits for estimates of gene linkage based on analysis of recombinant inbred strains. J Hered (1986) 3.68

Silkmoth chorion proteins: sequence analysis of the products of a multigene family. Proc Natl Acad Sci U S A (1978) 3.60

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry (1993) 3.54

Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase. Cell (1986) 3.51

Large-scale and automated DNA sequence determination. Science (1991) 3.45

Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha. Proc Natl Acad Sci U S A (1984) 3.43

The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene. Cell (1984) 3.41

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity (1996) 3.33

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity (1997) 3.33

T cell antigen receptors and the immunoglobulin supergene family. Cell (1985) 3.23

Cell-cell interaction in prostate gene regulation and cytodifferentiation. Proc Natl Acad Sci U S A (1997) 3.22

Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions. Proc Natl Acad Sci U S A (1979) 3.19

The structure, rearrangement and expression of D beta gene segments of the murine T-cell antigen receptor. Nature (1984) 3.18

DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen. Science (1982) 3.17

Mechanism of antibody diversity: germ line basis for variability. Science (1970) 3.05

Predominant use of a V alpha gene segment in mouse T-cell receptors for cytochrome c. Nature (1987) 2.99

Regeneration of adult axons in white matter tracts of the central nervous system. Nature (1998) 2.94

Understanding the adaptation of Halobacterium species NRC-1 to its extreme environment through computational analysis of its genome sequence. Genome Res (2001) 2.92

Tumor antigens induced by nontransforming mutants of polyoma virus. Cell (1978) 2.92

Positive selection of natural autoreactive B cells. Science (1999) 2.91

Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. Genome Res (1996) 2.91

Automated DNA diagnostics using an ELISA-based oligonucleotide ligation assay. Proc Natl Acad Sci U S A (1990) 2.88

Genes of the major histocompatibility complex in mouse and man. Science (1983) 2.88

Rearrangement of genetic information may produce immunoglobulin diversity. Nature (1979) 2.84

Mechanism of antibody synthesis: size differences between mouse kappa chains. Science (1967) 2.77

Zinc-dependent structure of a single-finger domain of yeast ADR1. Science (1988) 2.76

DNA sequence determination by hybridization: a strategy for efficient large-scale sequencing. Science (1993) 2.76

Clonal predominance of T cell receptors within the CD8+ CD45RO+ subset in normal human subjects. J Immunol (1993) 2.73

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes. J Neurosci (1991) 2.73

From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proc Natl Acad Sci U S A (2001) 2.66

Dynorphin-(1-13), an extraordinarily potent opioid peptide. Proc Natl Acad Sci U S A (1979) 2.66

Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord. J Neurosci (1999) 2.64

The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. Science (1996) 2.62

Statistical considerations for linkage analysis using recombinant inbred strains and backcrosses. Proc Natl Acad Sci U S A (1986) 2.60

Mouse Cmu heavy chain immunoglobulin gene segment contains three intervening sequences separating domains. Nature (1980) 2.52

Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate. EMBO J (1990) 2.52

Transplantation of kidneys from donors whose hearts have stopped beating. N Engl J Med (1998) 2.48

Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer. Nature (1982) 2.48

Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas. Gene (1999) 2.45

Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma. J Neurosci (1999) 2.43

Messenger RNA translation state: the second dimension of high-throughput expression screening. Proc Natl Acad Sci U S A (1999) 2.42

Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. Science (1982) 2.40

Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. Nature (1985) 2.40

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer (2009) 2.39

Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans. Blood (1998) 2.33

Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements. Nature (1986) 2.33

Rearrangement and transcription of the beta-chain genes of the T-cell antigen receptor in different types of murine lymphocytes. Nature (1985) 2.29

Expression of a myelin basic protein gene in transgenic shiverer mice: correction of the dysmyelinating phenotype. Cell (1987) 2.29

The joining of V and J gene segments creates antibody diversity. Nature (1980) 2.28

Antigen-presenting capabilities of human monocytes correlates with their expression of HLA-DS, an Ia determinant distinct from HLA-DR. J Immunol (1983) 2.25

The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. Immunity (1998) 2.23

Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins. Oncogene (1999) 2.21

Diversity and structure of human T-cell receptor beta-chain variable region genes. Proc Natl Acad Sci U S A (1986) 2.19

Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro. Exp Neurol (1990) 2.19

HIV-associated nephropathy in transgenic mice expressing HIV-1 genes. Virology (1991) 2.16

Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules. J Exp Med (1982) 2.15

Rearranged beta T cell receptor genes in a helper T cell clone specific for lysozyme: no correlation between V beta and MHC restriction. Cell (1985) 2.14

Anticipation in Crohn's disease may be influenced by gender and ethnicity of the transmitting parent. Am J Gastroenterol (1998) 2.14

The relative effects of FK506 and cyclosporine on short- and long-term kidney graft survival. Transplantation (1995) 2.13

Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine. J Intern Med (2012) 2.13

Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell (1984) 2.12

Equitable allocation of HLA-compatible kidneys for local pools and minorities. N Engl J Med (1994) 2.12

Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d. Science (1983) 2.12

Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36. Am J Hum Genet (1999) 2.12

Nanoliter scale PCR with TaqMan detection. Nucleic Acids Res (1997) 2.11

Survival of nationally shared, HLA-matched kidney transplants from cadaveric donors. The UNOS Scientific Renal Transplant Registry. N Engl J Med (1992) 2.09

Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat. J Clin Invest (1986) 2.07