Published in J Exp Med on December 01, 1977
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T-cell-specific murine Ia antigens: serology of I-J and I-E subregion specificities. J Exp Med (1978) 1.12
Regulatory mechanisms in cell-mediated immune responses. VII. Presence of I-C subregion determinants on mixed leukocyte reaction suppressor factor. J Exp Med (1979) 1.07
Evidence for two homologous, but nonidentical, Ia molecules determined by the I-EC subregion. J Exp Med (1979) 0.96
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Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
High resolution two-dimensional electrophoresis of proteins. J Biol Chem (1975) 133.45
Selective enzyme purification by affinity chromatography. Proc Natl Acad Sci U S A (1968) 10.63
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A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes. J Exp Med (1976) 6.11
Isolation of glycoproteins from pig lymphocyte plasma membrane using Lens culinaris phytohemagglutinin. Biochem Biophys Res Commun (1972) 3.05
Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes. J Exp Med (1976) 2.94
Structural and serological properties of murine Ia alloantigens. Transplant Rev (1976) 2.35
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Serologic and genetic aspects of murine Ia antigens. Transplant Rev (1976) 2.02
Serological and functional evidence for further subdivision of the I regions of the H-2 gene complex. Cold Spring Harb Symp Quant Biol (1977) 1.91
Evidence for more than one Ia antigenic specificity on molecules determined by the I-A subregion of the mouse major histocompatibility complex. J Immunol (1976) 1.49
Serologic and biochemical studies of the Ia system of the mouse H-2 gene complex. Further evidence for I-C subregion. J Immunol (1975) 1.36
Chemical characterization of products of the H-2 complex. Cold Spring Harb Symp Quant Biol (1977) 1.11
Histocompatibility-linked immune response genes. Science (1972) 16.79
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Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci U S A (1997) 6.99
G protein signaling events are activated at the leading edge of chemotactic cells. Cell (1998) 6.60
Association of high-molecular-weight proteins with microtubules and their role in microtubule assembly in vitro. Proc Natl Acad Sci U S A (1975) 6.35
A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes. J Exp Med (1976) 6.11
Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell (1988) 5.73
HL-A, immune-response genes, and disease. Lancet (1974) 5.67
Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol Today (1995) 5.32
Purification of tubulin and associated high molecular weight proteins from porcine brain and characterization of microtubule assembly in vitro. Ann N Y Acad Sci (1975) 5.26
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature (1993) 5.10
Microtubules: evidence for 13 protofilaments. J Cell Biol (1973) 4.91
Two-gene control of the expression of a murine Ia antigen. J Exp Med (1978) 4.79
Genetic control of the antibody response: relationship between immune response and histocompatibility (H-2) type. Science (1969) 4.53
Genetic control of the immune response. Mapping of the Ir-1 locus. J Exp Med (1972) 3.96
Monoclonal antibody against an Ir gene product? J Exp Med (1980) 3.88
Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat Med (2001) 3.56
Genetic control of the antibody response in inbred mice. Transfer of response by spleen cells and linkage to the major histocompatibility (H-2) locus. J Exp Med (1968) 3.52
Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis. Nature (1988) 3.46
On the complexity of self. Nature (1991) 3.43
A sensitive radioimmunoassay for detecting products translated from cloned DNA fragments. Cell (1978) 3.30
The localization of antigen in relation to specific antibody-producing cells. I. Use of a synthetic polypeptide [(T,G)-A--L] labelled with iodine-125. Immunology (1966) 3.09
Analysis of HLA-D region-associated molecules with monoclonal antibody. Proc Natl Acad Sci U S A (1979) 3.06
Genetic control of the immune response. The effect of thymectomy on the primary and secondary antibody response of mice to poly-L(tyr, glu)-poly-D, L-ala--poly-L-lys. J Exp Med (1972) 3.06
CD8(+) T cell-mediated spontaneous diabetes in neonatal mice. J Immunol (1996) 3.02
Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes. J Exp Med (1976) 2.94
In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon. J Exp Med (1987) 2.93
Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci U S A (1990) 2.88
The murine E alpha immune response gene. Cell (1983) 2.86
Detection of a common polypeptide chain in I--A and I--E sub-region immunoprecipitates. Mol Immunol (1979) 2.86
Endotoxin-induced uveitis in rats as a model for human disease. Nature (1980) 2.85
Contrasuppression. A novel immunoregulatory activity. J Exp Med (1981) 2.84
Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes. Proc Natl Acad Sci U S A (1983) 2.84
Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation. J Cell Biol (1997) 2.78
Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell (1989) 2.77
The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique. Proc Natl Acad Sci U S A (1987) 2.77
Histocompatibility (HL-A) antigens associated with systemic lupus erythematosus. A possible genetic predisposition to disease. N Engl J Med (1971) 2.69
Correlation of grain counts with radioactivity (125I and tritium) in autoradiography. Exp Cell Res (1966) 2.62
Protein clinical manifestations of primary tumors of the heart. Am J Med (1972) 2.61
Regions of allelic hypervariability in the murine A alpha immune response gene. Cell (1983) 2.53
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice. J Exp Med (1993) 2.47
Genetic control of the antibody response. II. Further analysis of the specificity of determinant-specific control, and genetic analysis of the response to (H,G)-A--L in CBA and C57 mice. J Exp Med (1967) 2.41
Histocompatibility-linked genetic control of disease susceptibility. Murine lymphocytic choriomeningitis virus infection. J Exp Med (1973) 2.39
Role of tubulin-associated proteins in microtubule nucleation and elongation. J Mol Biol (1977) 2.38
Monoclonal antibodies specific for Ia glycoproteins raised by immunization with activated T cells: possible role of T cellbound Ia antigens as targets of immunoregulatory T cells. J Immunol (1984) 2.35
A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines. Eur J Immunol (1989) 2.33
Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor. Cell (1990) 2.33
Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J Exp Med (1994) 2.33
A sequential model for peptide binding and transport by the transporters associated with antigen processing. Immunity (1994) 2.26
Autoimmune diseases: the failure of self tolerance. Science (1990) 2.24
Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation. J Immunol (1989) 2.24
The role of microtubules in the movement of pigment granules in teleost melanophores. J Cell Biol (1974) 2.21
Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci U S A (1988) 2.19
Genetic and functional analysis of the Ia antigens: their possible role in regulating the immune response. Transplant Rev (1976) 2.15
Genetic control of the antibody response to poly-L(Tyr,Glu)-poly-D,L-Ala--poly-L-Lys in C3H--CWB tetraparental mice. J Exp Med (1974) 2.14
Variable synthesis and expression of E alpha and Ae (E beta) Ia polypeptide chains in mice of different H-2 haplotypes. Immunogenetics (1981) 2.13
Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. Proc Natl Acad Sci U S A (1990) 2.13
A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. Immunity (1994) 2.09
Identity and polymerization-stimulatory activity of the nontubulin proteins associated with microtubules. Biochemistry (1977) 2.07
The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity (1996) 2.05
T cell recognition as the target for immune intervention in autoimmune disease. Cell (1989) 2.04
In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis. Proc Natl Acad Sci U S A (1981) 2.00
Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis. Arthritis Rheum (1977) 1.95
Genetic control of the antibody response. 3. Qualitative and quantitative characterization of the antibody response to (T,G)-A--L in CBA and C57 mice. J Immunol (1968) 1.94
Insulin-dependent diabetes mellitus: the initial lesion. N Engl J Med (1981) 1.93
Allelic variation in the DR subregion of the human major histocompatibility complex. Proc Natl Acad Sci U S A (1987) 1.92
Complete nucleotide sequence of a gene encoding a functional human class I histocompatibility antigen (HLA-CW3). EMBO J (1984) 1.92
Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling. J Exp Med (1997) 1.92
Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis. J Exp Med (1988) 1.89
Isolation of a 45-kDa fragment from the kinesin heavy chain with enhanced ATPase and microtubule-binding activities. J Biol Chem (1989) 1.88
Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis. Proc Natl Acad Sci U S A (1996) 1.85
Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors. Proc Natl Acad Sci U S A (1989) 1.84
Treatment of (NZB x NZW)F1 disease with anti-I-A monoclonal antibodies. J Exp Med (1983) 1.79
CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice. J Immunol (1997) 1.79
The nature of the antigenic determinant in a genetic control of the antibody response. J Exp Med (1969) 1.74
Characterization of HLA-D-region antigens by two-dimensional gel electrophoresis. Molecular-genotyping. J Exp Med (1980) 1.73
Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-beta receptor-IgG1 fusion protein. Proc Natl Acad Sci U S A (1996) 1.71
The murine Ia alpha chains, E alpha and A alpha, show a surprising degree of sequence homology. Proc Natl Acad Sci U S A (1983) 1.69
Selective turnover and shedding of H-2K and H-2D antigens is controlled by the major histocompatibility complex. Implications for H-2-restricted recognition. J Exp Med (1980) 1.68
Gene conversion between murine class II major histocompatibility complex loci. Functional and molecular evidence from the bm 12 mutant. J Exp Med (1984) 1.66
Mapping of the class II region of the human major histocompatibility complex by pulsed-field gel electrophoresis. Nature (1986) 1.64
Tla types of H-2 congenic and recombinant mice. Transplantation (1974) 1.62
Two subsets of epithelial cells in the thymic medulla. J Exp Med (1992) 1.59
Cross-reactivity between H-2K and H-2D products. I. Evidence for extensive and reciprocal serological cross-reactivity. J Exp Med (1975) 1.58
The genetic control of antibody specificity. J Exp Med (1969) 1.58
Structure of murine Ia antigens: partial NH2-terminal amino acid sequences of products of the I-E or I-C subregion. Proc Natl Acad Sci U S A (1977) 1.56
Genetic control of the immune response. Frequency and characteristics of antigen-binding cells in high and low responder mice. J Exp Med (1973) 1.55
Isolation and characterization of a cDNA clone for the murine I-E beta polypeptide chain. Proc Natl Acad Sci U S A (1983) 1.54
Genetic control of radiation leukemia virus-induced tumorigenesis. I. Role of the major murine histocompatibility complex, H-2. J Exp Med (1977) 1.54